Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2y3p | SM8 | DNA gyrase subunit A |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2y3p | SM8 | DNA gyrase subunit A | / | 1.000 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.506 | |
| 1g2v | TTP | Glucose-1-phosphate thymidylyltransferase | / | 0.503 | |
| 3pce | 3HP | Protocatechuate 3,4-dioxygenase alpha chain | 1.13.11.3 | 0.500 | |
| 3pce | 3HP | Protocatechuate 3,4-dioxygenase beta chain | 1.13.11.3 | 0.500 | |
| 4qxq | 1YE | Stimulator of interferon genes protein | / | 0.497 | |
| 2rl1 | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.491 | |
| 4eak | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.488 | |
| 2pam | TYD | TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase | 5.3.2.3 | 0.487 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.485 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.484 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.483 | |
| 1g0r | THM | Glucose-1-phosphate thymidylyltransferase | / | 0.482 | |
| 1np7 | FAD | Cryptochrome DASH | / | 0.482 | |
| 2bun | FAD | AppA protein | / | 0.480 | |
| 2geu | COK | Pantothenate kinase | 2.7.1.33 | 0.480 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.480 | |
| 4wud | ANP | DNA gyrase subunit B | / | 0.480 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.479 | |
| 4h8n | NDP | NADPH-dependent conjugated polyketone reductase C2 | / | 0.479 | |
| 4n9i | PCG | Catabolite expression activator | / | 0.479 | |
| 1eny | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.476 | |
| 4die | C5P | Cytidylate kinase | / | 0.476 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.476 | |
| 1kqc | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.475 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.475 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.475 | |
| 4jc5 | 1K5 | Stimulator of interferon genes protein | / | 0.475 | |
| 4qxr | 1YE | Stimulator of interferon genes protein | / | 0.474 | |
| 3lfm | 3DT | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.473 | |
| 2bxq | IMN | Serum albumin | / | 0.472 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.472 | |
| 5ijz | NAP | NADP-specific glutamate dehydrogenase | 1.4.1.4 | 0.472 | |
| 1evj | NAD | Glucose--fructose oxidoreductase | 1.1.99.28 | 0.471 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.471 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.471 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.470 | |
| 3enk | UPG | UDP-glucose 4-epimerase | / | 0.470 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.470 | |
| 3c0i | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.469 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.469 | |
| 3qw4 | U5P | Orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative | / | 0.468 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.468 | |
| 1mp0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.467 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.467 | |
| 3swq | EPU | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.467 | |
| 3uyl | TYD | Probable NDP-rhamnosyltransferase | / | 0.467 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.467 | |
| 5d3q | GDP | Dynamin-1 | 3.6.5.5 | 0.466 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.465 | |
| 1qrs | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.465 | |
| 3pch | CHB | Protocatechuate 3,4-dioxygenase beta chain | 1.13.11.3 | 0.465 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.465 | |
| 4qxp | 1YE | Stimulator of interferon genes protein | / | 0.465 | |
| 4u03 | GTP | Cyclic GMP-AMP synthase | / | 0.465 | |
| 4xq6 | FMN | Dihydroorotate dehydrogenase (quinone) | / | 0.465 | |
| 1kr2 | TAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.464 | |
| 2bxm | IMN | Serum albumin | / | 0.464 | |
| 2ewm | NAD | (S)-1-Phenylethanol dehydrogenase | 1.1.1.311 | 0.464 | |
| 2xvv | 9DN | Serum albumin | / | 0.464 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.464 | |
| 3rud | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.464 | |
| 4bjz | FAD | Probable salicylate monooxygenase | / | 0.464 | |
| 4dyp | 0MS | Nucleoprotein | / | 0.464 | |
| 4yaf | 2AM | NADPH--cytochrome P450 reductase | / | 0.464 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.464 | |
| 5fa1 | C5P | Putative N-acetyl glucosaminyl transferase | / | 0.464 | |
| 1p4a | PCP | Pur operon repressor | / | 0.463 | |
| 2wvl | GDD | Mannosyl-3-phosphogylcerate synthase | / | 0.463 | |
| 3lm8 | VIB | Thiamine pyrophosphokinase | 2.7.6.2 | 0.463 | |
| 4u7w | NDP | MxaA | / | 0.463 | |
| 1yre | COA | Uncharacterized protein | / | 0.462 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.462 | |
| 2ep7 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.462 | |
| 2oor | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.462 | |
| 3to3 | ATP | Petrobactin biosynthesis protein AsbB | / | 0.462 | |
| 4a4z | ANP | Antiviral helicase SKI2 | 3.6.4.13 | 0.462 | |
| 4riy | ADP | Epidermal growth factor receptor | 2.7.10.1 | 0.462 | |
| 4xj3 | GTP | Cyclic GMP-AMP synthase | / | 0.462 | |
| 5cfl | C2E | Stimulator of interferon genes protein | / | 0.462 | |
| 1iqr | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.461 | |
| 1u2y | GOX | Pancreatic alpha-amylase | / | 0.461 | |
| 3u4o | 08E | Genome polyprotein | 2.7.7.48 | 0.461 | |
| 3udq | 09E | Beta-secretase 1 | 3.4.23.46 | 0.461 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.460 | |
| 2j5x | GSP | ADP-ribosylation factor 6 | / | 0.460 | |
| 2z9d | FMN | FMN-dependent NADH-azoreductase | / | 0.460 | |
| 3kb6 | NAD | D-lactate dehydrogenase | / | 0.460 | |
| 4e2b | FMN | Dehydrogenase | / | 0.460 | |
| 4e5l | DBH | Polymerase acidic protein | / | 0.460 | |
| 4h2n | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.460 | |
| 4u0o | MTA | Lipoyl synthase 2 | / | 0.460 | |
| 5fm7 | ADP | RuvB-like helicase | / | 0.460 | |
| 5kwv | ANP | Pantothenate synthetase | / | 0.460 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.459 | |
| 2ww4 | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.459 | |
| 3ioc | A5D | Pantothenate synthetase | 6.3.2.1 | 0.459 | |
| 3otf | CMP | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | / | 0.459 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 4cr8 | NAD | N-acylmannosamine 1-dehydrogenase | 1.1.1.233 | 0.459 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.459 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.458 | |
| 1ypk | CCR | Prothrombin | 3.4.21.5 | 0.458 | |
| 2x0r | NAD | Malate dehydrogenase | / | 0.458 | |
| 3c4v | LIP | D-inositol 3-phosphate glycosyltransferase | 2.4.1.250 | 0.458 | |
| 3hgs | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.458 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.457 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 3sxp | NAD | ADP-L-glycero-D-mannoheptose-6-epimerase | / | 0.457 | |
| 3vmm | P0D | Alanine--anticapsin ligase | / | 0.457 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.457 | |
| 4emt | C2E | Stimulator of interferon genes protein | / | 0.457 | |
| 4f5y | C2E | Stimulator of interferon genes protein | / | 0.457 | |
| 4in4 | 4ID | Kelch-like ECH-associated protein 1 | / | 0.457 | |
| 5a88 | ADP | Riboflavin biosynthesis protein RibF | 2.7.1.26 | 0.457 | |
| 5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.457 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 1i24 | UPG | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.456 | |
| 2qn3 | F55 | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.456 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.456 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.456 | |
| 4c13 | UML | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase | / | 0.456 | |
| 4zrn | UPG | UDP-glucose 4-epimerase, putative | / | 0.456 | |
| 5kgp | ACO | Predicted acetyltransferase | / | 0.456 | |
| 2nv6 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.455 | |
| 2w6o | OA3 | Biotin carboxylase | 6.3.4.14 | 0.455 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 3gue | UPG | UTP-glucose-1-phosphate uridylyltransferase 2, putative | / | 0.455 | |
| 3jzd | NAD | Maleylacetate reductase | / | 0.455 | |
| 3ljt | LA3 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.455 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.455 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 0.455 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.455 | |
| 4h0v | NAD | Iota toxin component Ia | / | 0.455 | |
| 4u0m | GTP | Cyclic GMP-AMP synthase | / | 0.455 | |
| 5bsf | NAD | Pyrroline-5-carboxylate reductase | / | 0.455 | |
| 1i59 | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.454 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.454 | |
| 2bvs | 2CE | Prothrombin | 3.4.21.5 | 0.454 | |
| 2ome | NAD | C-terminal-binding protein 2 | / | 0.454 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.454 | |
| 3uhm | RFN | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.454 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.454 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.454 | |
| 4jl5 | ADP | Adenylate kinase | / | 0.454 | |
| 5ftf | ADP | TPR domain protein | / | 0.454 | |
| 1gc5 | ADP | ADP-dependent glucokinase | 2.7.1.147 | 0.453 | |
| 1kqn | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.453 | |
| 1kqo | DND | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.453 | |
| 1ptj | SND | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.453 | |
| 1ryd | NDP | Glucose--fructose oxidoreductase | 1.1.99.28 | 0.453 | |
| 1u1c | BAU | Uridine phosphorylase | 2.4.2.3 | 0.453 | |
| 2i3g | NAP | N-acetyl-gamma-glutamyl-phosphate reductase | 1.2.1.38 | 0.453 | |
| 4b3a | TAC | Tetracycline repressor protein class D | / | 0.453 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.453 | |
| 4nmd | FDA | Bifunctional protein PutA | / | 0.453 | |
| 1kvs | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.452 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.452 | |
| 1u8v | FAD | 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase | / | 0.452 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.452 | |
| 2b36 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.452 | |
| 2fna | ADP | Uncharacterized protein | / | 0.452 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.452 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.452 | |
| 2x0i | NAI | Malate dehydrogenase | / | 0.452 | |
| 3ed1 | GA3 | Gibberellin receptor GID1 | / | 0.452 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.452 | |
| 3tvq | DQH | Multifunctional cyclase-dehydratase-3-O-methyl transferase TcmN | 2.1.1 | 0.452 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.452 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 5c1g | GDU | Histo-blood group ABO system transferase | / | 0.452 | |
| 1d6w | 00R | Prothrombin | 3.4.21.5 | 0.451 | |
| 1ds7 | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.451 | |
| 1dxy | NAD | D-2-hydroxyisocaproate dehydrogenase | 1.1.1 | 0.451 | |
| 1e90 | MYC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.451 | |
| 1tow | CRZ | Fatty acid-binding protein, adipocyte | / | 0.451 | |
| 1udb | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.451 | |
| 1wc4 | APC | Adenylate cyclase | / | 0.451 | |
| 2ou5 | FMN | Pyridoxamine 5'-phosphate oxidase-related FMN-binding protein | / | 0.451 | |
| 2pak | TYD | TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase | 5.3.2.3 | 0.451 | |
| 3dj4 | UD1 | Bifunctional protein GlmU | / | 0.451 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.451 | |
| 4dpy | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.451 | |
| 4zu4 | 4TG | WxcM-like protein | / | 0.451 | |
| 5ftc | ADP | TPR domain protein | / | 0.451 | |
| 5ify | UMP | Glucose-1-phosphate thymidylyltransferase | / | 0.451 | |
| 5kgh | ACO | Predicted acetyltransferase | / | 0.451 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.450 | |
| 1cjt | FOK | Adenylate cyclase type 2 | / | 0.450 | |
| 1cjt | FOK | Adenylate cyclase type 5 | / | 0.450 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 1omo | NAD | Alanine dehydrogenase | / | 0.450 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.450 | |
| 2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.450 | |
| 2w6n | OA2 | Biotin carboxylase | 6.3.4.14 | 0.450 | |
| 2zsd | COA | Pantothenate kinase | 2.7.1.33 | 0.450 | |
| 3kb1 | ADP | Iron-sulfur cluster carrier protein | / | 0.450 | |
| 3wb2 | YGP | Uncharacterized protein MJ0488 | / | 0.450 | |
| 4itm | ATP | Tetraacyldisaccharide 4'-kinase | / | 0.450 | |
| 4kgk | GTP | Uncharacterized protein | / | 0.450 | |
| 4o4e | ATP | Kinase | / | 0.450 | |
| 1k02 | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.449 | |
| 1n2e | APC | Pantothenate synthetase | 6.3.2.1 | 0.449 | |
| 1nm6 | L86 | Prothrombin | 3.4.21.5 | 0.449 | |
| 1rz1 | NAD | Phenol 2-hydroxylase component B | / | 0.449 | |
| 2ekp | NAD | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.449 | |
| 2ges | COK | Pantothenate kinase | 2.7.1.33 | 0.449 | |
| 2get | COK | Pantothenate kinase | 2.7.1.33 | 0.449 | |
| 2ntv | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.449 | |
| 2vtb | FAD | Cryptochrome DASH, chloroplastic/mitochondrial | / | 0.449 | |
| 3b2s | B2S | Trichothecene 3-O-acetyltransferase | / | 0.449 | |
| 3gka | FMN | N-ethylmaleimide reductase | / | 0.449 | |
| 3w2n | ROD | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.449 | |
| 4isu | IKM | Glutamate receptor 2 | / | 0.449 | |
| 1bsv | NDP | GDP-L-fucose synthase | / | 0.448 | |
| 1l7e | NAI | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.448 | |
| 1lrj | UD1 | UDP-glucose 4-epimerase | 5.1.3.2 | 0.448 | |
| 1udc | UFM | UDP-glucose 4-epimerase | 5.1.3.2 | 0.448 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.448 | |
| 2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.448 | |
| 2p2m | PRX | Acetyl-coenzyme A synthetase | / | 0.448 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.448 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.448 | |
| 2xvw | 9NR | Serum albumin | / | 0.448 | |
| 2y3s | TIR | TamL | / | 0.448 | |
| 3aty | FMN | Prostaglandin F2a synthase | / | 0.448 | |
| 3c1y | 2BA | DNA integrity scanning protein DisA | / | 0.448 | |
| 3etg | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.448 | |
| 3ggj | 25H | Hypoxanthine-guanine phosphoribosyltransferase | 2.4.2.8 | 0.448 | |
| 3mvq | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.448 | |
| 3ut5 | LOC | Tubulin beta chain | / | 0.448 | |
| 3v4t | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.448 | |
| 4giu | 636 | Anthranilate phosphoribosyltransferase | / | 0.448 | |
| 4ivg | ANP | TNF receptor-associated protein 1 | / | 0.448 | |
| 5hg0 | SAM | Pantothenate synthetase | / | 0.448 | |
| 1bxk | NAD | dTDP-glucose 4,6-dehydratase 2 | / | 0.447 | |
| 1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.447 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.447 | |
| 1icv | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.447 | |
| 1lol | XMP | Orotidine 5'-phosphate decarboxylase | 4.1.1.23 | 0.447 | |
| 1lwi | NAP | 3-alpha-hydroxysteroid dehydrogenase | 1.1.1.50 | 0.447 | |
| 1n2s | NAI | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.447 | |
| 2bn4 | NAP | NADPH--cytochrome P450 reductase | / | 0.447 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.447 | |
| 2ivn | ANP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.447 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.447 | |
| 2q46 | NAP | Uncharacterized protein At5g02240 | / | 0.447 | |
| 2qbu | SAH | Precorrin-2 methyltransferase | / | 0.447 | |
| 2qoc | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.447 | |
| 2yx6 | ADP | Uncharacterized protein | / | 0.447 | |
| 3fr4 | F8A | Fatty acid-binding protein, adipocyte | / | 0.447 | |
| 3iaa | TYD | CalG2 | / | 0.447 | |
| 3lfc | Z86 | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.447 | |
| 3ska | 053 | Genome polyprotein | 2.7.7.48 | 0.447 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.447 | |
| 4e2d | FMN | Dehydrogenase | / | 0.447 | |
| 4gpb | GFP | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.447 | |
| 4loi | 1YC | Stimulator of interferon genes protein | / | 0.447 | |
| 4qai | FMN | NADPH dehydrogenase | / | 0.447 | |
| 4xgu | ADP | Putative pachytene checkpoint protein 2 | / | 0.447 | |
| 5fs7 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.447 | |
| 1hzj | UD1 | UDP-glucose 4-epimerase | / | 0.446 | |
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.446 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.446 | |
| 2gev | COK | Pantothenate kinase | 2.7.1.33 | 0.446 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.446 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.446 | |
| 2ok7 | FAD | Ferredoxin--NADP reductase, apicoplast | / | 0.446 | |
| 2p9g | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.446 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.446 | |
| 2rd2 | QSI | Glutamine--tRNA ligase | 6.1.1.18 | 0.446 | |
| 2xy3 | DUP | SPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS | 3.6.1.23 | 0.446 | |
| 3cic | 316 | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 3orf | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.446 | |
| 3qiy | QI1 | Botulinum neurotoxin type A | 3.4.24.69 | 0.446 | |
| 3umv | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.446 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.446 | |
| 4dya | 0MF | Nucleoprotein | / | 0.446 | |
| 4fvz | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.446 | |
| 4i1c | 1BE | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.446 | |
| 4loh | 1SY | Stimulator of interferon genes protein | / | 0.446 | |
| 2ahr | NAP | Pyrroline-5-carboxylate reductase | / | 0.445 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.445 | |
| 2udp | UPP | UDP-glucose 4-epimerase | 5.1.3.2 | 0.445 | |
| 2v5a | LZL | Biotin carboxylase | 6.3.4.14 | 0.445 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 2xvq | 9DS | Serum albumin | / | 0.445 | |
| 2zi2 | 24U | Prothrombin | 3.4.21.5 | 0.445 | |
| 3a4o | STU | Tyrosine-protein kinase Lyn | 2.7.10.2 | 0.445 | |
| 3cid | 318 | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3img | BZ3 | Pantothenate synthetase | 6.3.2.1 | 0.445 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.445 | |
| 4a6r | TA8 | Probable aminotransferase | / | 0.445 | |
| 4kgm | ATP | Uncharacterized protein | / | 0.445 | |
| 4wuc | ANP | DNA gyrase subunit B | / | 0.445 | |
| 5f8e | SAH | Possible transcriptional regulatory protein | / | 0.445 | |
| 1h74 | ADP | Homoserine kinase | 2.7.1.39 | 0.444 | |
| 1qrr | UPG | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.444 | |
| 1u0h | FOK | Adenylate cyclase type 2 | / | 0.444 | |
| 1u0h | FOK | Adenylate cyclase type 5 | / | 0.444 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 2xtn | GTP | GTPase IMAP family member 2 | / | 0.444 | |
| 3c35 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.444 | |
| 3mel | TPP | Thiamin pyrophosphokinase family protein | / | 0.444 | |
| 3mt8 | 17T | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.444 | |
| 3oee | ANP | ATP synthase subunit alpha, mitochondrial | / | 0.444 | |
| 3oee | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.444 | |
| 3t1t | GDP | Probable gliding protein mglA | / | 0.444 | |
| 4eso | NAP | Putative oxidoreductase | / | 0.444 | |
| 4feu | 537 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.444 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.444 | |
| 4qms | 1N1 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.444 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.444 | |
| 5cdg | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.444 | |
| 1ek6 | UPG | UDP-glucose 4-epimerase | / | 0.443 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.443 | |
| 1n7h | GDP | GDP-mannose 4,6 dehydratase 2 | 4.2.1.47 | 0.443 | |
| 1nuq | NXX | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.443 | |
| 1p44 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 1u71 | MXA | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 2bri | ANP | Uridylate kinase | 2.7.4.22 | 0.443 | |
| 2rkv | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.443 | |
| 3a1c | ACP | Probable copper-exporting P-type ATPase A | 3.6.3.54 | 0.443 | |
| 3cvy | FAD | RE11660p | / | 0.443 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.443 | |
| 3wfj | NAD | 2-dehydropantoate 2-reductase | / | 0.443 | |
| 3wg6 | NDP | NADPH-dependent conjugated polyketone reductase C1 | / | 0.443 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.443 | |
| 4ge9 | 0L0 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.443 | |
| 4isk | 1JY | Thymidylate synthase | / | 0.443 | |
| 4nm9 | FAD | Bifunctional protein PutA | / | 0.443 | |
| 4xsv | CTP | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.443 | |
| 5a06 | NDP | Glucose-fructose oxidoreductase | / | 0.443 | |
| 1e2n | RCA | Thymidine kinase | / | 0.442 | |
| 1f20 | NAP | Nitric oxide synthase, brain | 1.14.13.39 | 0.442 | |
| 1mew | XMP | Inosine-5'-monophosphate dehydrogenase | / | 0.442 | |
| 1q43 | CMP | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 | / | 0.442 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 1r6u | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.442 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.442 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.442 | |
| 1sny | NAP | LD36273p | / | 0.442 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 2ck3 | ANP | ATP synthase subunit alpha, mitochondrial | / | 0.442 | |
| 2ck3 | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.442 | |
| 2uzf | CAA | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.442 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.442 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.442 | |
| 2y8q | ADP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.442 | |
| 3bl7 | DD1 | m7GpppX diphosphatase | 3.6.1.59 | 0.442 | |
| 3h03 | UBP | Glutamate receptor 2 | / | 0.442 | |
| 3p82 | FMN | Pentaerythritol tetranitrate reductase | / | 0.442 | |
| 3qiz | QI2 | Botulinum neurotoxin type A | 3.4.24.69 | 0.442 | |
| 3zhy | FM6 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.442 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.442 | |
| 4bfy | ZVY | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.442 | |
| 4jql | VJ6 | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 1a5b | IGP | Tryptophan synthase alpha chain | / | 0.441 | |
| 1a9z | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.441 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.441 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.441 | |
| 1hyg | NAP | L-2-hydroxycarboxylate dehydrogenase (NAD(P)(+)) | / | 0.441 | |
| 1kqd | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.441 | |
| 1mzs | 669 | 3-oxoacyl-[acyl-carrier-protein] synthase 3 | / | 0.441 | |
| 1o97 | FAD | Electron transfer flavoprotein subunit alpha | / | 0.441 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.441 | |
| 1xkv | ATP | Phosphoenolpyruvate carboxykinase (ATP) | / | 0.441 | |
| 1ylu | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.441 | |
| 1zgi | 382 | Prothrombin | 3.4.21.5 | 0.441 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.441 | |
| 2fsv | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.441 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.441 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.441 | |
| 2os1 | BB2 | Peptide deformylase | / | 0.441 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.441 | |
| 2x86 | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.441 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 0.441 | |
| 3g2h | KOT | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.441 | |
| 3gep | 24H | Hypoxanthine-guanine phosphoribosyltransferase | 2.4.2.8 | 0.441 | |
| 3ime | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.441 | |
| 3qwc | 98P | Prothrombin | 3.4.21.5 | 0.441 | |
| 3sdk | P3N | Proteasome subunit beta type-5 | 3.4.25.1 | 0.441 | |
| 3sdk | P3N | Proteasome subunit beta type-6 | 3.4.25.1 | 0.441 | |
| 4frk | DWD | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4lk3 | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.441 | |
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.441 | |
| 4nhy | PD2 | Prolyl 3-hydroxylase OGFOD1 | 1.14.11 | 0.441 | |
| 5a3b | APR | SIR2 family protein | / | 0.441 | |
| 5c8w | PCG | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.441 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.440 | |
| 1c9k | 5GP | Bifunctional adenosylcobalamin biosynthesis protein CobU | / | 0.440 | |
| 1d4p | BPP | Prothrombin | 3.4.21.5 | 0.440 | |
| 1kp2 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.440 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.440 | |
| 1oyt | FSN | Prothrombin | 3.4.21.5 | 0.440 | |
| 1s20 | NAD | 2,3-diketo-L-gulonate reductase | 1.1.1.130 | 0.440 | |
| 1toi | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.440 | |
| 1u2g | APR | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.440 | |
| 1ywn | LIF | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.440 | |
| 1zdf | UPG | Glycogenin-1 | 2.4.1.186 | 0.440 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.440 | |
| 2e8u | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.440 | |
| 2iqg | F2I | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 2jh0 | 701 | Prothrombin | 3.4.21.5 | 0.440 | |
| 2rds | 1PL | 1-deoxypentalenic acid 11-beta-hydroxylase | 1.14.11.35 | 0.440 | |
| 2v59 | LZK | Biotin carboxylase | 6.3.4.14 | 0.440 | |
| 2w6q | OA5 | Biotin carboxylase | 6.3.4.14 | 0.440 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 2ym8 | YM8 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 2zc9 | 22U | Prothrombin | 3.4.21.5 | 0.440 | |
| 2zsh | GA3 | Gibberellin receptor GID1A | 3 | 0.440 | |
| 2zsi | GA4 | Gibberellin receptor GID1A | 3 | 0.440 | |
| 3arv | SAU | Chitinase A | / | 0.440 | |
| 3ipk | PMS | Surface protein adhesin | / | 0.440 | |
| 3m2u | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.440 | |
| 3m2v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.440 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.440 | |
| 3w1r | MRO | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.440 | |
| 3x2w | ATP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.440 | |
| 3zia | ATP | ATP synthase subunit alpha, mitochondrial | / | 0.440 | |
| 4aut | FAD | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.440 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.440 | |
| 4dbv | NDP | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.440 | |
| 4dwv | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.440 | |
| 4f5d | C2E | Stimulator of interferon genes protein | / | 0.440 | |
| 4g3s | UD1 | Bifunctional protein GlmU | / | 0.440 | |
| 4kne | 1CY | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 4kp7 | 1UQ | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic | 1.1.1.267 | 0.440 | |
| 4lol | 1YE | Stimulator of interferon genes protein | / | 0.440 | |
| 4rvg | TYD | D-mycarose 3-C-methyltransferase | / | 0.440 |