sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2xvv | 9DN | Serum albumin |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2xvv | 9DN | Serum albumin | / | 1.000 | |
| 2xvw | 9NR | Serum albumin | / | 0.818 | |
| 3b9l | AZZ | Serum albumin | / | 0.664 | |
| 2bxq | IMN | Serum albumin | / | 0.656 | |
| 2bxm | IMN | Serum albumin | / | 0.603 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.467 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.464 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.461 | |
| 3ddw | 055 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.454 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.453 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.451 | |
| 3dd1 | 25D | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.451 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.443 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.440 | |
| 3lpi | Z74 | Beta-secretase 1 | 3.4.23.46 | 0.440 |