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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2xupTZ5Acetylcholinesterase3.1.1.7

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2xupTZ5Acetylcholinesterase3.1.1.71.000
2xuqTZ4Acetylcholinesterase3.1.1.70.716
2xuiTZ5Acetylcholinesterase3.1.1.70.624
2xukTZ5Acetylcholinesterase3.1.1.70.564
2xuhTZ4Acetylcholinesterase3.1.1.70.551
1q84TZ4Acetylcholinesterase3.1.1.70.550
2xujTZ5Acetylcholinesterase3.1.1.70.548
2xuoTZ4Acetylcholinesterase3.1.1.70.540
1q83TZ5Acetylcholinesterase3.1.1.70.530
4m0f1YKAcetylcholinesterase3.1.1.70.525
2j3qTFLAcetylcholinesterase3.1.1.70.517
2xufTZ4Acetylcholinesterase3.1.1.70.513
1zgbA1EAcetylcholinesterase3.1.1.70.512
4arbC57Acetylcholinesterase3.1.1.70.510
4araC56Acetylcholinesterase3.1.1.70.499
1odcA8BAcetylcholinesterase3.1.1.70.496
4ey7E20Acetylcholinesterase3.1.1.70.496
1ut6A8NAcetylcholinesterase3.1.1.70.489
1eveE20Acetylcholinesterase3.1.1.70.483
1u65CP0Acetylcholinesterase3.1.1.70.481
2w6cBM4Acetylcholinesterase3.1.1.70.480
1w4lGL8Acetylcholinesterase3.1.1.70.475
1zgcA2EAcetylcholinesterase3.1.1.70.475
2ckmAA7Acetylcholinesterase3.1.1.70.471
2xugTZ4Acetylcholinesterase3.1.1.70.471
1h22E10Acetylcholinesterase3.1.1.70.469
2ha6SCKAcetylcholinesterase3.1.1.70.463
4b7zQ4QAcetylcholinesterase3.1.1.70.449
2jf0HBPAcetylcholinesterase3.1.1.70.445
2cmfF11Acetylcholinesterase3.1.1.70.441