Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2xto | GDP | GTPase IMAP family member 2 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2xto | GDP | GTPase IMAP family member 2 | / | 1.000 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.503 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.502 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.497 | |
| 3bb3 | GDP | Translocase of chloroplast 33, chloroplastic | 3.6.5 | 0.496 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.493 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.490 | |
| 3vwe | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.489 | |
| 1jnz | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.488 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.487 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.485 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.483 | |
| 2xtn | GTP | GTPase IMAP family member 2 | / | 0.482 | |
| 5a3c | NAD | SIR2 family protein | / | 0.480 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.479 | |
| 2r26 | CMC | Citrate synthase | 2.3.3.16 | 0.479 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.479 | |
| 4kuh | CAA | 3-hydroxybutyryl-CoA dehydrogenase | / | 0.479 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.478 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.478 | |
| 4z24 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.478 | |
| 1cg6 | MTA | S-methyl-5'-thioadenosine phosphorylase | / | 0.477 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.477 | |
| 4z63 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.475 | |
| 3kpk | FAD | Sulfide-quinone reductase | / | 0.474 | |
| 3t4n | ADP | 5'-AMP-activated protein kinase subunit gamma | / | 0.474 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.473 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.472 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.471 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.471 | |
| 2fiw | ACO | GCN5-related N-acetyltransferase:Aminotransferase, class-II | / | 0.471 | |
| 4eb7 | PLP | Cysteine desulfurase IscS 2 | / | 0.471 | |
| 1jue | FMN | Dihydroorotate dehydrogenase A (fumarate) | 1.3.98.1 | 0.469 | |
| 2fja | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.468 | |
| 3uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.468 | |
| 4u0m | GTP | Cyclic GMP-AMP synthase | / | 0.467 | |
| 1fm7 | DFV | Chalcone--flavonone isomerase 1 | 5.5.1.6 | 0.466 | |
| 1qrp | HH0 | Pepsin A-4 | 3.4.23.1 | 0.466 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.466 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.466 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.466 | |
| 3cge | COA | Coenzyme A disulfide reductase | / | 0.466 | |
| 3h5s | H5S | Genome polyprotein | 2.7.7.48 | 0.466 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.465 | |
| 1tys | DHF | Thymidylate synthase | / | 0.465 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.465 | |
| 2vmy | FFO | Serine hydroxymethyltransferase | / | 0.465 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.464 | |
| 2o7p | NAP | Riboflavin biosynthesis protein RibD | / | 0.464 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.464 | |
| 4cjx | 9L9 | C-1-tetrahydrofolate synthase, cytoplasmic, putative | / | 0.464 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.463 | |
| 3jqp | A2P | Ferredoxin--NADP reductase, apicoplast | / | 0.463 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.463 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.463 | |
| 3uyl | TYD | Probable NDP-rhamnosyltransferase | / | 0.463 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.462 | |
| 3koy | Z97 | D-ornithine 4,5-aminomutase subunit beta | / | 0.462 | |
| 4u9y | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.462 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.462 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.461 | |
| 2c3q | GTX | Glutathione S-transferase theta-1 | 2.5.1.18 | 0.461 | |
| 3i59 | N6S | CRP-like cAMP-activated global transcriptional regulator | / | 0.461 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.461 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.460 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.460 | |
| 1rby | GAR | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.460 | |
| 2bd0 | NAP | Sepiapterin reductase | / | 0.460 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.460 | |
| 3bbt | FMM | Receptor tyrosine-protein kinase erbB-4 | 2.7.10.1 | 0.460 | |
| 3ha5 | SFG | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.460 | |
| 3sgt | P09 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | / | 0.460 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.460 | |
| 1txz | APR | Probable ADP-ribose 1''-phosphate phosphatase YML087W | 3.1.3.84 | 0.459 | |
| 3ad9 | NAD | Subunit alpha of sarocosine oxidase | / | 0.459 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.459 | |
| 3qwb | NDP | Probable quinone oxidoreductase | 1.6.5.5 | 0.459 | |
| 5doz | NDP | JamJ | / | 0.459 | |
| 5fm7 | ADP | RuvB-like helicase | / | 0.459 | |
| 1dc6 | NAD | Glyceraldehyde-3-phosphate dehydrogenase A | / | 0.458 | |
| 1knr | FAD | L-aspartate oxidase | 1.4.3.16 | 0.458 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.458 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.458 | |
| 3aw9 | NAD | NAD-dependent epimerase/dehydratase | / | 0.458 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 4qi5 | FAD | Cellobiose dehydrogenase | / | 0.458 | |
| 1k6t | XN1 | Gag-Pol polyprotein | 3.4.23.16 | 0.457 | |
| 1mg5 | NAI | Alcohol dehydrogenase | 1.1.1.1 | 0.457 | |
| 1yqx | NAP | Sinapyl alcohol dehydrogenase | / | 0.457 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.457 | |
| 2w71 | L23 | Biotin carboxylase | 6.3.4.14 | 0.457 | |
| 2xaa | NAD | Secondary alcohol dehydrogenase | / | 0.457 | |
| 3cgb | COA | Coenzyme A disulfide reductase | / | 0.457 | |
| 3dds | 26B | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.457 | |
| 4irn | FAD | AnaB | / | 0.457 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.457 | |
| 4z26 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.457 | |
| 5a88 | ADP | Riboflavin biosynthesis protein RibF | 2.7.1.26 | 0.457 | |
| 1ae1 | NAP | Tropinone reductase 1 | / | 0.456 | |
| 1tj0 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.456 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.456 | |
| 1z6t | ADP | Apoptotic protease-activating factor 1 | / | 0.456 | |
| 2ew5 | Y12 | Peptide deformylase | / | 0.456 | |
| 2hrb | NAP | Carbonyl reductase [NADPH] 3 | 1.1.1.184 | 0.456 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 3i59 | N6R | CRP-like cAMP-activated global transcriptional regulator | / | 0.456 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.456 | |
| 3uwl | FOZ | Thymidylate synthase | / | 0.456 | |
| 3w8f | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.456 | |
| 4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.456 | |
| 5dp2 | NAP | CurF | / | 0.456 | |
| 1e5q | NDP | Saccharopine dehydrogenase [NADP(+), L-glutamate-forming] | 1.5.1.10 | 0.455 | |
| 2ch6 | ADP | N-acetyl-D-glucosamine kinase | 2.7.1.59 | 0.455 | |
| 2jfg | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.455 | |
| 2rgo | FAD | Alpha-Glycerophosphate Oxidase | / | 0.455 | |
| 2xvq | 9DS | Serum albumin | / | 0.455 | |
| 3f3s | NAD | Lambda-crystallin homolog | / | 0.455 | |
| 4if5 | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.455 | |
| 4jlk | 1NO | Deoxycytidine kinase | 2.7.1.74 | 0.455 | |
| 4wdg | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.455 | |
| 5kgh | ACO | Predicted acetyltransferase | / | 0.455 | |
| 1ftl | DNQ | Glutamate receptor 2 | / | 0.454 | |
| 2c54 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.454 | |
| 2cvz | NDP | 3-hydroxyisobutyrate dehydrogenase | / | 0.454 | |
| 2in6 | 839 | Wee1-like protein kinase | 2.7.10.2 | 0.454 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 3mgd | ACO | Predicted acetyltransferase | / | 0.454 | |
| 3say | OFT | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.454 | |
| 4h80 | 04T | Aldehyde dehydrogenase, dimeric NADP-preferring | / | 0.454 | |
| 4mk7 | 28O | Genome polyprotein | 2.7.7.48 | 0.454 | |
| 5l3r | GCP | Cell division protein FtsY homolog, chloroplastic | / | 0.454 | |
| 1ib6 | NAD | Malate dehydrogenase | / | 0.453 | |
| 1piw | NAP | NADP-dependent alcohol dehydrogenase 6 | 1.1.1.2 | 0.453 | |
| 1rkx | NAD | CDP-D-glucose-4,6-dehydratase | / | 0.453 | |
| 1ykf | NAP | NADP-dependent isopropanol dehydrogenase | 1.1.1.80 | 0.453 | |
| 3bi6 | 396 | Wee1-like protein kinase | 2.7.10.2 | 0.453 | |
| 3lki | ATP | Fructokinase | / | 0.453 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.453 | |
| 3wle | NAD | (R)-specific carbonyl reductase | / | 0.453 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.453 | |
| 4z64 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.453 | |
| 5a3b | APR | SIR2 family protein | / | 0.453 | |
| 1cjc | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.452 | |
| 1ijh | FAD | Cholesterol oxidase | 1.1.3.6 | 0.452 | |
| 1ot7 | IU5 | Bile acid receptor | / | 0.452 | |
| 1pr9 | NAP | L-xylulose reductase | 1.1.1.10 | 0.452 | |
| 1ygj | RMC | Pyridoxal kinase | 2.7.1.35 | 0.452 | |
| 2e16 | SAH | Diphthine synthase | / | 0.452 | |
| 2jkv | NAP | 6-phosphogluconate dehydrogenase, decarboxylating | 1.1.1.44 | 0.452 | |
| 2o12 | FMN | Chorismate synthase | / | 0.452 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.452 | |
| 3e2s | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.452 | |
| 3frq | ERY | Erythromycin resistance repressor protein | / | 0.452 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.452 | |
| 3ggo | NAI | Prephenate dehydrogenase | / | 0.452 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.452 | |
| 3jzm | ATP | Circadian clock protein kinase KaiC | 2.7.11.1 | 0.452 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.452 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 4dc1 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.452 | |
| 4i5e | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.452 | |
| 4opi | FDA | Conserved Archaeal protein | / | 0.452 | |
| 4qai | FMN | NADPH dehydrogenase | / | 0.452 | |
| 4rvu | NDP | Probable quinone reductase Qor (NADPH:quinone reductase) (Zeta-crystallin homolog protein) | / | 0.452 | |
| 4u2l | SFD | Cholesterol oxidase | 1.1.3.6 | 0.452 | |
| 4yau | FAD | NADPH--cytochrome P450 reductase | / | 0.452 | |
| 5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.452 | |
| 1osv | CHC | Bile acid receptor | / | 0.451 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.451 | |
| 2cvw | GDP | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.451 | |
| 2fjd | SFD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.451 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.451 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.451 | |
| 2uxu | NAR | HTH-type transcriptional regulator TtgR | / | 0.451 | |
| 2ylz | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.451 | |
| 3clb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.451 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.451 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 3nx4 | NAP | Putative oxidoreductase | / | 0.451 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 3r5z | F42 | Uncharacterized protein | / | 0.451 | |
| 3sdk | P3N | Proteasome subunit beta type-5 | 3.4.25.1 | 0.451 | |
| 3sdk | P3N | Proteasome subunit beta type-6 | 3.4.25.1 | 0.451 | |
| 3t1k | ANP | Heat shock protein HSP 90-alpha | / | 0.451 | |
| 3w32 | W32 | Epidermal growth factor receptor | 2.7.10.1 | 0.451 | |
| 3zbz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.451 | |
| 4feh | FAD | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.451 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.451 | |
| 4is3 | NAD | 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2 | 1.17.98.1 | 0.451 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.451 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.451 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.451 | |
| 1e6w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.450 | |
| 1kqu | BR4 | Phospholipase A2, membrane associated | / | 0.450 | |
| 2g8a | UMP | Thymidylate synthase | / | 0.450 | |
| 2hck | QUE | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.450 | |
| 2xb5 | I7T | Tetracycline repressor protein class D | / | 0.450 | |
| 3c0i | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.450 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.450 | |
| 3ls8 | AJZ | Phosphatidylinositol 3-kinase catalytic subunit type 3 | 2.7.1.137 | 0.450 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 4anw | O92 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.450 | |
| 4bkj | STI | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.450 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.450 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.450 | |
| 4ktl | 1CQ | Cytochrome P450 | / | 0.450 | |
| 4o0l | NDP | NADPH-dependent 3-quinuclidinone reductase | / | 0.450 | |
| 4zla | BES | Cytosol aminopeptidase | 3.4.11.1 | 0.450 | |
| 5kgj | ACO | Predicted acetyltransferase | / | 0.450 | |
| 1b16 | NAQ | Alcohol dehydrogenase | 1.1.1.1 | 0.449 | |
| 1h73 | ANP | Homoserine kinase | 2.7.1.39 | 0.449 | |
| 1tdu | CB3 | Thymidylate synthase | / | 0.449 | |
| 1x8b | 824 | Wee1-like protein kinase | 2.7.10.2 | 0.449 | |
| 2fzm | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.449 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.449 | |
| 2hqp | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 3bhr | THG | Thymidylate synthase | / | 0.449 | |
| 3cgc | COA | Coenzyme A disulfide reductase | / | 0.449 | |
| 3cgd | COA | Coenzyme A disulfide reductase | / | 0.449 | |
| 3eyh | IZA | Tyrosine-protein kinase JAK1 | / | 0.449 | |
| 3ioc | A5D | Pantothenate synthetase | 6.3.2.1 | 0.449 | |
| 3qof | GDP | Atlastin-1 | 3.6.5 | 0.449 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.449 | |
| 4knz | CB3 | Thymidylate synthase | / | 0.449 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.449 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.449 | |
| 5hwr | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.449 | |
| 1dfo | FFO | Serine hydroxymethyltransferase | 2.1.2.1 | 0.448 | |
| 1ork | ATC | Tetracycline repressor protein class D | / | 0.448 | |
| 1ra3 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1rc4 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 2cmj | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.448 | |
| 2f4j | VX6 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.448 | |
| 2hq9 | FAD | Mll6688 protein | / | 0.448 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.448 | |
| 3m13 | FAD | Monomeric sarcosine oxidase | 1.5.3.1 | 0.448 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 3pe2 | E1B | Casein kinase II subunit alpha | 2.7.11.1 | 0.448 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.448 | |
| 3zbn | COA | 3-ketoacyl-CoA thiolase-like protein | / | 0.448 | |
| 4b65 | FAD | L-ornithine N(5)-monooxygenase | / | 0.448 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.448 | |
| 4g2f | C07 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.448 | |
| 4i6a | HMG | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.448 | |
| 4nbu | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.448 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.447 | |
| 1il0 | CAA | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.447 | |
| 2ewm | NAD | (S)-1-Phenylethanol dehydrogenase | 1.1.1.311 | 0.447 | |
| 2gfd | RDA | Endoplasmin | / | 0.447 | |
| 2jiz | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.447 | |
| 3bv2 | P38 | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.447 | |
| 3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.447 | |
| 3ox1 | 695 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.447 | |
| 3t3c | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.447 | |
| 4eb5 | PLP | Cysteine desulfurase IscS 2 | / | 0.447 | |
| 4iah | 1DX | Alr2278 protein | / | 0.447 | |
| 4qxp | 1YE | Stimulator of interferon genes protein | / | 0.447 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.447 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.447 | |
| 1dgh | NDP | Catalase | 1.11.1.6 | 0.446 | |
| 1dor | FMN | Dihydroorotate dehydrogenase A (fumarate) | 1.3.98.1 | 0.446 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.446 | |
| 1kp2 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.446 | |
| 1okz | UCN | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.446 | |
| 1qlh | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.446 | |
| 1ty8 | ADP | Probable ADP-ribose 1''-phosphate phosphatase YML087W | 3.1.3.84 | 0.446 | |
| 1ya3 | STR | Mineralocorticoid receptor | / | 0.446 | |
| 2fto | CB3 | Thymidylate synthase | / | 0.446 | |
| 2fzw | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.446 | |
| 2g2h | P16 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.446 | |
| 2yph | QQY | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.446 | |
| 3dvl | ATP | Circadian clock protein kinase KaiC | 2.7.11.1 | 0.446 | |
| 3ids | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.446 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.446 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.446 | |
| 3oqu | A8S | Abscisic acid receptor PYL9 | / | 0.446 | |
| 3qrw | NDP | Putative ketoacyl reductase | 1.3.1 | 0.446 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.446 | |
| 4jlc | SU6 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.446 | |
| 4l4x | NDP | AmphI | / | 0.446 | |
| 4pan | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.446 | |
| 4ubt | COA | Steroid 3-ketoacyl-CoA thiolase | / | 0.446 | |
| 4xvq | GNP | GTPase HRas | / | 0.446 | |
| 4ynt | FDA | Glucose oxidase, putative | / | 0.446 | |
| 4z44 | FAD | Flavin-dependent tryptophan halogenase PrnA | 1.14.19.9 | 0.446 | |
| 1equ | EQI | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.445 | |
| 1m52 | P17 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.445 | |
| 1ma0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.445 | |
| 1u4o | NDD | L-lactate dehydrogenase | 1.1.1.27 | 0.445 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.445 | |
| 1xzq | FON | tRNA modification GTPase MnmE | 3.6.5 | 0.445 | |
| 2gcg | NDP | Glyoxylate reductase/hydroxypyruvate reductase | 1.1.1.79 | 0.445 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.445 | |
| 2zjm | F1M | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 3bi2 | FAD | Polyamine oxidase FMS1 | / | 0.445 | |
| 3fsk | RO6 | Mitogen-activated protein kinase 14 | / | 0.445 | |
| 3jzi | JZL | Biotin carboxylase | 6.3.4.14 | 0.445 | |
| 3lqs | PSZ | D-alanine aminotransferase | 2.6.1.21 | 0.445 | |
| 3tqh | NDP | Quinone oxidoreductase | / | 0.445 | |
| 4ozn | ATP | Ammonium transporter | / | 0.445 | |
| 2bx8 | AZQ | Serum albumin | / | 0.444 | |
| 2dwb | ANP | Aurora kinase A | 2.7.11.1 | 0.444 | |
| 2hr8 | SAH | Diphthine synthase | / | 0.444 | |
| 2p9c | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.444 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.444 | |
| 2wdz | NAD | Galactitol dehydrogenase | / | 0.444 | |
| 2zja | ACP | ATP-dependent DNA helicase Hel308 | / | 0.444 | |
| 3b9l | AZZ | Serum albumin | / | 0.444 | |
| 3bnk | FMN | Flavoredoxin | / | 0.444 | |
| 3nhp | HGZ | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.444 | |
| 3vqs | JT1 | Genome polyprotein | / | 0.444 | |
| 4b4d | FAD | Ferredoxin-NADP reductase | / | 0.444 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.444 | |
| 4d86 | ADP | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.444 | |
| 4dh6 | 0KN | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 4e8y | IHA | D-beta-D-heptose 7-phosphate kinase | / | 0.444 | |
| 5fkl | TDC | Tetracycline repressor protein class D | / | 0.444 | |
| 5lc1 | NAD | L-threonine 3-dehydrogenase | / | 0.444 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.444 | |
| 1d9i | 00P | Prothrombin | 3.4.21.5 | 0.443 | |
| 1g4p | FQP | Thiamine-phosphate synthase | / | 0.443 | |
| 1mew | XMP | Inosine-5'-monophosphate dehydrogenase | / | 0.443 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.443 | |
| 1tl7 | ONM | Adenylate cyclase type 2 | / | 0.443 | |
| 1tl7 | ONM | Adenylate cyclase type 5 | / | 0.443 | |
| 1xq6 | NAP | Uncharacterized protein At5g02240 | / | 0.443 | |
| 2y99 | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | 1.3.1.56 | 0.443 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.443 | |
| 3a4o | STU | Tyrosine-protein kinase Lyn | 2.7.10.2 | 0.443 | |
| 3c14 | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.443 | |
| 3etg | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.443 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.443 | |
| 3kyb | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.443 | |
| 3nhj | A2Z | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.443 | |
| 3thr | C2F | Glycine N-methyltransferase | 2.1.1.20 | 0.443 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.443 | |
| 4do3 | 0LA | Fatty-acid amide hydrolase 1 | 3.5.1.99 | 0.443 | |
| 4fhf | 0TT | Spore photoproduct lyase | / | 0.443 | |
| 4fj0 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.443 | |
| 4hjo | AQ4 | Epidermal growth factor receptor | 2.7.10.1 | 0.443 | |
| 4jld | ADP | Adenylate kinase | / | 0.443 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.443 | |
| 4tkg | 09L | Tankyrase-2 | 2.4.2.30 | 0.443 | |
| 5br7 | FAD | UDP-galactopyranose mutase | / | 0.443 | |
| 5cts | CMC | Citrate synthase, mitochondrial | 2.3.3.1 | 0.443 | |
| 1f8g | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.442 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.442 | |
| 1hnc | GDN | Glutathione S-transferase Mu 2 | 2.5.1.18 | 0.442 | |
| 1qor | NDP | Quinone oxidoreductase 1 | / | 0.442 | |
| 1suw | NAP | NAD kinase | / | 0.442 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 1xu7 | CPS | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.442 | |
| 2b8j | ADN | Class B acid phosphatase | 3.1.3.2 | 0.442 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 3d2p | COA | Amino-acid acetyltransferase | / | 0.442 | |
| 3d7k | D7K | Benzaldehyde lyase | / | 0.442 | |
| 3q3c | NAD | NAD-dependent L-serine dehydrogenase | / | 0.442 | |
| 3syi | FAD | Sulfide-quinone reductase | / | 0.442 | |
| 3w0g | W07 | Vitamin D3 receptor | / | 0.442 | |
| 4jlm | 1NN | Deoxycytidine kinase | 2.7.1.74 | 0.442 | |
| 4jx1 | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 4kp7 | 1UQ | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic | 1.1.1.267 | 0.442 | |
| 4pd6 | URI | Nucleoside permease | / | 0.442 | |
| 4pl0 | ANP | Microcin-J25 export ATP-binding/permease protein McjD | / | 0.442 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 5fs7 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.442 | |
| 4s0v | SUV | Orexin receptor type 2 | / | 0.442 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1n5d | NDP | Carbonyl reductase [NADPH] 1 | / | 0.441 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.441 | |
| 2g5c | NAD | Prephenate dehydrogenase | / | 0.441 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.441 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.441 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.441 | |
| 2q0k | NAP | Thioredoxin reductase | 1.8.1.9 | 0.441 | |
| 2r04 | W71 | Genome polyprotein | / | 0.441 | |
| 2rbe | ZMG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
| 3ajr | NAD | NDP-sugar epimerase | / | 0.441 | |
| 3ch6 | 311 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
| 3ds6 | A17 | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.441 | |
| 3hk1 | B64 | Fatty acid-binding protein, adipocyte | / | 0.441 | |
| 3i4b | Z48 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.441 | |
| 3ol5 | SAW | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 3p8z | SAH | Genome polyprotein | 2.1.1.56 | 0.441 | |
| 3q71 | AR6 | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.441 | |
| 3rj9 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.441 | |
| 3rud | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.441 | |
| 3uax | NOS | Purine nucleoside phosphorylase DeoD-type | / | 0.441 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.441 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.441 | |
| 4c58 | 824 | Cyclin-G-associated kinase | 2.7.11.1 | 0.441 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 0.441 | |
| 4dpw | AGS | Mevalonate diphosphate decarboxylase | / | 0.441 | |
| 4dx9 | SER_ALA_VAL_THR | Integrin beta-1 | / | 0.441 | |
| 4dx9 | SER_ALA_VAL_THR | Integrin beta-1-binding protein 1 | / | 0.441 | |
| 4gdp | FAD | Polyamine oxidase FMS1 | / | 0.441 | |
| 4gyy | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.441 | |
| 4nd4 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.441 | |
| 4rf2 | NAP | NADPH dependent R-specific alcohol dehydrogenase | / | 0.441 | |
| 4ri1 | ACO | UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase | 2.3.1.202 | 0.441 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.441 | |
| 4xgi | NAD | Glutamate dehydrogenase | / | 0.441 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.441 | |
| 1b4v | FAD | Cholesterol oxidase | 1.1.3.6 | 0.440 | |
| 1f4g | TP4 | Thymidylate synthase | / | 0.440 | |
| 1fxs | NAP | GDP-L-fucose synthase | / | 0.440 | |
| 1s5k | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.440 | |
| 1tdu | DUR | Thymidylate synthase | / | 0.440 | |
| 1wvg | APR | CDP-glucose 4,6-dehydratase | 4.2.1.45 | 0.440 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.440 | |
| 1y7l | ASN_LEU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.440 | |
| 2bgj | FAD | NADPH:ferredoxin reductase | / | 0.440 | |
| 2gn8 | NAP | UDP-N-acetylglucosamine 4,6-dehydratase (inverting) | 4.2.1.115 | 0.440 | |
| 2gvd | FKP | Adenylate cyclase type 2 | / | 0.440 | |
| 2gvd | FKP | Adenylate cyclase type 5 | / | 0.440 | |
| 2nq8 | ZID | Enoyl-ACP reductase | / | 0.440 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.440 | |
| 2q2q | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.440 | |
| 2rew | REW | Peroxisome proliferator-activated receptor alpha | / | 0.440 | |
| 2x7j | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.440 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.440 | |
| 2zts | ADP | Uncharacterized protein | / | 0.440 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.440 | |
| 3dge | ADP | Sensor histidine kinase | / | 0.440 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3elu | SAM | Methyltransferase | / | 0.440 | |
| 3hky | IX6 | Genome polyprotein | 2.7.7.48 | 0.440 | |
| 3kga | LX9 | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.440 | |
| 3kjr | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.440 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.440 | |
| 3ndv | AIC | Beta-peptidyl aminopeptidase BapA | / | 0.440 | |
| 3uay | ADN | Purine nucleoside phosphorylase DeoD-type | / | 0.440 | |
| 3v9y | 24L | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 4a9u | A9U | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.440 | |
| 4b5p | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.440 | |
| 4c9o | CAM | Cytochrome P450 | / | 0.440 | |
| 4gs4 | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.440 | |
| 4l7f | 1V5 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.440 | |
| 4n8i | COA | Putative 4-hydroxybutyrate coenzyme A transferase | / | 0.440 | |
| 4nd2 | A3D | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.440 | |
| 5e5h | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.440 | |
| 5ein | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.440 | |
| 5idw | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.440 | |
| 5iqe | GNP | Bifunctional AAC/APH | 2.3.1 | 0.440 | |
| 5kf2 | ACO | Predicted acetyltransferase | / | 0.440 |