sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2xfs | J01 | Uncharacterized protein |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2xfs | J01 | Uncharacterized protein | / | 1.000 | |
| 2xh9 | J01 | Uncharacterized protein | / | 0.554 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.481 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.469 | |
| 1nuu | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.467 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.465 | |
| 4fm8 | 0UQ | Beta-secretase 1 | 3.4.23.46 | 0.460 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.456 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.449 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.447 | |
| 1nuq | NXX | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.445 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.444 | |
| 4j2w | FAD | Kynurenine 3-monooxygenase | / | 0.444 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.442 | |
| 3c21 | 2BA | DNA integrity scanning protein DisA | / | 0.442 |