sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2xd6 | XD6 | ATP-dependent molecular chaperone HSP82 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2xd6 | XD6 | ATP-dependent molecular chaperone HSP82 | / | 1.000 | |
| 2iwx | M1S | ATP-dependent molecular chaperone HSP82 | / | 0.643 | |
| 3hyz | 42C | Heat shock protein HSP 90-alpha | / | 0.617 | |
| 4ce3 | L4V | ATP-dependent molecular chaperone HSP82 | / | 0.617 | |
| 2wer | RDC | ATP-dependent molecular chaperone HSP82 | / | 0.613 | |
| 2iwu | NP5 | ATP-dependent molecular chaperone HSP82 | / | 0.612 | |
| 2bre | KJ2 | ATP-dependent molecular chaperone HSP82 | / | 0.609 | |
| 4ce1 | 7FK | ATP-dependent molecular chaperone HSP82 | / | 0.604 | |
| 2gqp | PA7 | Endoplasmin | / | 0.597 | |
| 1bgq | RDC | ATP-dependent molecular chaperone HSP82 | / | 0.588 | |
| 2qg0 | A94 | Heat shock protein HSP 90-alpha | / | 0.585 | |
| 2wi6 | ZZ6 | Heat shock protein HSP 90-alpha | / | 0.584 | |
| 3r4p | FU7 | Heat shock protein HSP 90-alpha | / | 0.584 | |
| 1am1 | ADP | ATP-dependent molecular chaperone HSP82 | / | 0.582 | |
| 1qy5 | NEC | Endoplasmin | / | 0.582 | |
| 2xx4 | 13I | ATP-dependent molecular chaperone HSP82 | / | 0.579 | |
| 1uy8 | PU5 | Heat shock protein HSP 90-alpha | / | 0.576 | |
| 1u0z | RDC | Endoplasmin | / | 0.575 | |
| 1byq | ADP | Heat shock protein HSP 90-alpha | / | 0.573 | |
| 2gfd | RDA | Endoplasmin | / | 0.573 | |
| 3ekr | PY9 | Heat shock protein HSP 90-alpha | / | 0.573 | |
| 4ce2 | BO5 | ATP-dependent molecular chaperone HSP82 | / | 0.571 | |
| 1uy7 | PU4 | Heat shock protein HSP 90-alpha | / | 0.570 | |
| 3eko | PYU | Heat shock protein HSP 90-alpha | / | 0.569 | |
| 3hek | BD0 | Heat shock protein HSP 90-alpha | / | 0.569 | |
| 2wep | ADP | ATP-dependent molecular chaperone HSP82 | / | 0.568 | |
| 3vha | VHA | Heat shock protein HSP 90-alpha | / | 0.567 | |
| 1uyk | PUX | Heat shock protein HSP 90-alpha | / | 0.565 | |
| 1uym | PU3 | Heat shock protein HSP 90-beta | / | 0.565 | |
| 4bqj | XKL | Heat shock protein HSP 90-alpha | / | 0.563 | |
| 3k97 | 4CD | Heat shock protein HSP 90-alpha | / | 0.562 | |
| 2bz5 | AB4 | Heat shock protein HSP 90-alpha | / | 0.560 | |
| 3rlr | 3RR | Heat shock protein HSP 90-alpha | / | 0.558 | |
| 2iws | NP4 | ATP-dependent molecular chaperone HSP82 | / | 0.557 | |
| 2xk2 | ADP | Heat shock protein HSP 90-alpha | / | 0.556 | |
| 3hhu | 819 | Heat shock protein HSP 90-alpha | / | 0.556 | |
| 2xx2 | 13C | ATP-dependent molecular chaperone HSP82 | / | 0.555 | |
| 2yee | 2EC | Heat shock protein HSP 90-alpha | / | 0.555 | |
| 2bt0 | CT5 | Heat shock protein HSP 90-alpha | / | 0.552 | |
| 2fwz | H71 | Heat shock protein HSP 90-alpha | / | 0.552 | |
| 3c11 | GDM | ATP-dependent molecular chaperone HSP82 | / | 0.552 | |
| 1qy8 | RDI | Endoplasmin | / | 0.551 | |
| 1yc1 | 4BC | Heat shock protein HSP 90-alpha | / | 0.551 | |
| 3r4n | FU5 | Heat shock protein HSP 90-alpha | / | 0.551 | |
| 3ft8 | MOJ | Heat shock protein HSP 90-alpha | / | 0.548 | |
| 1uye | PU9 | Heat shock protein HSP 90-alpha | / | 0.545 | |
| 4as9 | 4QS | ATP-dependent molecular chaperone HSP82 | / | 0.545 | |
| 4gqt | ADP | Heat shock protein 90 | / | 0.545 | |
| 4jql | VJ6 | Heat shock protein HSP 90-alpha | / | 0.545 | |
| 2fwy | H64 | Heat shock protein HSP 90-alpha | / | 0.544 | |
| 4egi | B2J | Heat shock protein HSP 90-alpha | / | 0.543 | |
| 1ysz | NEC | Endoplasmin | / | 0.542 | |
| 2h55 | DZ8 | Heat shock protein HSP 90-alpha | / | 0.542 | |
| 3r4o | FU3 | Heat shock protein HSP 90-alpha | / | 0.542 | |
| 4fcr | 0TM | Heat shock protein HSP 90-alpha | / | 0.541 | |
| 2vw5 | BC6 | ATP-dependent molecular chaperone HSP82 | / | 0.538 | |
| 2yef | ANP | Heat shock protein HSP 90-alpha | / | 0.538 | |
| 3t10 | ACP | Heat shock protein HSP 90-alpha | / | 0.538 | |
| 3hz1 | 42C | Heat shock protein HSP 90-alpha | / | 0.537 | |
| 1uy9 | PU6 | Heat shock protein HSP 90-alpha | / | 0.536 | |
| 1uyi | PUZ | Heat shock protein HSP 90-alpha | / | 0.536 | |
| 3inw | JZB | Heat shock protein HSP 90-alpha | / | 0.536 | |
| 2wi7 | 2KL | Heat shock protein HSP 90-alpha | / | 0.535 | |
| 2brc | CT5 | ATP-dependent molecular chaperone HSP82 | / | 0.534 | |
| 1uyd | PU8 | Heat shock protein HSP 90-alpha | / | 0.533 | |
| 1uyf | PU1 | Heat shock protein HSP 90-alpha | / | 0.533 | |
| 1yet | GDM | Heat shock protein HSP 90-alpha | / | 0.531 | |
| 2qg2 | A91 | Heat shock protein HSP 90-alpha | / | 0.530 | |
| 3inx | JZC | Heat shock protein HSP 90-alpha | / | 0.530 | |
| 4nh8 | 2LC | Heat shock protein HSP 90-alpha | / | 0.530 | |
| 2xhr | C0P | Heat shock protein HSP 90-alpha | / | 0.528 | |
| 3hz5 | Z64 | Heat shock protein HSP 90-alpha | / | 0.528 | |
| 1amw | ADP | ATP-dependent molecular chaperone HSP82 | / | 0.527 | |
| 4egk | RDC | Heat shock protein HSP 90-alpha | / | 0.527 | |
| 1y4s | ADP | Chaperone protein HtpG | / | 0.526 | |
| 3t2s | AGS | Heat shock protein HSP 90-alpha | / | 0.526 | |
| 2ykj | YKJ | Heat shock protein HSP 90-alpha | / | 0.525 | |
| 3o0i | P54 | Heat shock protein HSP 90-alpha | / | 0.525 | |
| 3opd | HIE | Heat shock protein 83 | / | 0.523 | |
| 3ied | AN2 | HSP90 | / | 0.522 | |
| 3rlq | 3RQ | Heat shock protein HSP 90-alpha | / | 0.521 | |
| 1u0y | PA7 | Endoplasmin | / | 0.520 | |
| 2fxs | RDA | ATP-dependent molecular chaperone HSP82 | / | 0.520 | |
| 2fyp | RDE | Endoplasmin | / | 0.520 | |
| 3omu | IBD | Heat shock protein 83 | / | 0.519 | |
| 4asf | 62U | ATP-dependent molecular chaperone HSP82 | / | 0.519 | |
| 1osf | KOS | Heat shock protein HSP 90-alpha | / | 0.518 | |
| 1yc4 | 43P | Heat shock protein HSP 90-alpha | / | 0.518 | |
| 4efu | EFU | Heat shock protein HSP 90-alpha | / | 0.518 | |
| 1u2o | NEC | Endoplasmin | / | 0.516 | |
| 4eft | EFT | Heat shock protein HSP 90-alpha | / | 0.516 | |
| 2byh | 2D7 | Heat shock protein HSP 90-alpha | / | 0.515 | |
| 2cgf | P2N | ATP-dependent molecular chaperone HSP82 | / | 0.515 | |
| 2yeg | XQG | Heat shock protein HSP 90-alpha | / | 0.514 | |
| 2wi5 | ZZ5 | Heat shock protein HSP 90-alpha | / | 0.513 | |
| 2xjx | XJX | Heat shock protein HSP 90-alpha | / | 0.513 | |
| 1uyc | PU7 | Heat shock protein HSP 90-alpha | / | 0.512 | |
| 3k98 | 1RC | Heat shock protein HSP 90-alpha | / | 0.512 | |
| 2exl | GDM | Endoplasmin | / | 0.511 | |
| 2xab | VHD | Heat shock protein HSP 90-alpha | / | 0.510 | |
| 4ipe | ANP | TNF receptor-associated protein 1 | / | 0.510 | |
| 4xcl | AGS | Heat shock cognate 90 kDa protein | / | 0.510 | |
| 4xdm | GDM | Heat shock cognate 90 kDa protein | / | 0.509 | |
| 4asg | 814 | ATP-dependent molecular chaperone HSP82 | / | 0.508 | |
| 3b28 | B2X | Heat shock protein HSP 90-alpha | / | 0.507 | |
| 2byi | 2DD | Heat shock protein HSP 90-alpha | / | 0.506 | |
| 3wha | WHA | Heat shock protein HSP 90-alpha | / | 0.506 | |
| 2yei | XQI | Heat shock protein HSP 90-alpha | / | 0.505 | |
| 3t1k | ANP | Heat shock protein HSP 90-alpha | / | 0.505 | |
| 2ykc | YKC | Heat shock protein HSP 90-alpha | / | 0.504 | |
| 1uyh | PU0 | Heat shock protein HSP 90-alpha | / | 0.503 | |
| 2ior | ADP | Chaperone protein HtpG | / | 0.503 | |
| 3q5k | D1U | Heat shock protein 83-1 | / | 0.501 | |
| 1yc3 | 4BC | Heat shock protein HSP 90-alpha | / | 0.500 | |
| 2vcj | 2EQ | Heat shock protein HSP 90-alpha | / | 0.498 | |
| 3o6o | 94M | Heat shock protein 83 | / | 0.498 | |
| 2qfo | A13 | Heat shock protein HSP 90-alpha | / | 0.497 | |
| 2wi4 | ZZ4 | Heat shock protein HSP 90-alpha | / | 0.497 | |
| 5f5r | ANP | Heat shock protein 75 kDa, mitochondrial | / | 0.497 | |
| 1nhh | ANP | DNA mismatch repair protein MutL | / | 0.494 | |
| 2xjj | L81 | Heat shock protein HSP 90-alpha | / | 0.493 | |
| 2hg1 | N5O | Endoplasmin | / | 0.492 | |
| 2yej | ZZ3 | Heat shock protein HSP 90-alpha | / | 0.492 | |
| 2esa | GDM | Endoplasmin | / | 0.490 | |
| 4b7p | 9UN | Heat shock protein HSP 90-alpha | / | 0.490 | |
| 2ykb | YKB | Heat shock protein HSP 90-alpha | / | 0.489 | |
| 2vwc | BC2 | ATP-dependent molecular chaperone HSP82 | / | 0.488 | |
| 2xcm | ADP | Cytosolic heat shock protein 90 | / | 0.488 | |
| 2vci | 2GJ | Heat shock protein HSP 90-alpha | / | 0.487 | |
| 4xc0 | ACP | Heat shock cognate 90 kDa protein | / | 0.486 | |
| 4xcj | ADP | Heat shock cognate 90 kDa protein | / | 0.485 | |
| 3ozc | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.484 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.484 | |
| 2xx5 | 13N | ATP-dependent molecular chaperone HSP82 | / | 0.483 | |
| 2zkj | ADP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | 2.7.11.2 | 0.483 | |
| 2bu8 | ADP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.482 | |
| 2brb | PFQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.481 | |
| 2bsm | BSM | Heat shock protein HSP 90-alpha | / | 0.481 | |
| 4bqg | 50Q | Heat shock protein HSP 90-alpha | / | 0.481 | |
| 1nvq | UCN | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.480 | |
| 2oh0 | 2PY | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.480 | |
| 2yk2 | YJW | Heat shock protein HSP 90-alpha | / | 0.480 | |
| 2p6k | SAH | Diphthine synthase | / | 0.479 | |
| 3k99 | PFT | Heat shock protein HSP 90-alpha | / | 0.479 | |
| 3mnr | SD1 | Heat shock protein HSP 90-alpha | / | 0.479 | |
| 2e0a | ANP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | 2.7.11.2 | 0.478 | |
| 4awo | 99B | Heat shock protein HSP 90-alpha | / | 0.477 | |
| 1ydt | IQB | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.476 | |
| 2ye4 | 2FY | Heat shock protein HSP 90-alpha | / | 0.476 | |
| 3d2r | ADP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | 2.7.11.2 | 0.476 | |
| 2hch | N5A | Endoplasmin | / | 0.475 | |
| 2o1u | ANP | Endoplasmin | / | 0.475 | |
| 4z1f | H71 | Heat shock protein 75 kDa, mitochondrial | / | 0.475 | |
| 2wi2 | ZZ3 | Heat shock protein HSP 90-alpha | / | 0.474 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.474 | |
| 3qdd | 94M | Heat shock protein HSP 90-alpha | / | 0.473 | |
| 2wi1 | ZZ2 | Heat shock protein HSP 90-alpha | / | 0.472 | |
| 2zdy | ADP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | 2.7.11.2 | 0.472 | |
| 2uwd | 2GG | Heat shock protein HSP 90-alpha | / | 0.471 | |
| 2yi5 | YI5 | Heat shock protein HSP 90-alpha | / | 0.471 | |
| 3rlp | 3RP | Heat shock protein HSP 90-alpha | / | 0.471 | |
| 4awp | 99A | Heat shock protein HSP 90-alpha | / | 0.471 | |
| 4egh | 0OY | Heat shock protein HSP 90-alpha | / | 0.471 | |
| 4awq | 592 | Heat shock protein HSP 90-alpha | / | 0.470 | |
| 3tki | S25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.469 | |
| 2uzb | C75 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.467 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.467 | |
| 2cgw | 3C3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.466 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.466 | |
| 3ft5 | MO8 | Heat shock protein HSP 90-alpha | / | 0.466 | |
| 4fsn | A58 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.466 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.465 | |
| 1z59 | ADP | Type 2 DNA topoisomerase 6 subunit B | / | 0.464 | |
| 2qfo | A51 | Heat shock protein HSP 90-alpha | / | 0.463 | |
| 3peh | IBD | Endoplasmin homolog, putative | / | 0.463 | |
| 3pej | BC2 | Endoplasmin homolog, putative | / | 0.463 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.462 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.462 | |
| 4fob | 0US | ALK tyrosine kinase receptor | 2.7.10.1 | 0.462 | |
| 1u59 | STU | Tyrosine-protein kinase ZAP-70 | 2.7.10.2 | 0.461 | |
| 2p6i | SAH | Diphthine synthase | / | 0.461 | |
| 2xjg | XJG | Heat shock protein HSP 90-alpha | / | 0.461 | |
| 4fod | 0UV | ALK tyrosine kinase receptor | 2.7.10.1 | 0.461 | |
| 1zrz | BI1 | Protein kinase C iota type | 2.7.11.13 | 0.460 | |
| 2ic3 | HBY | Gag-Pol polyprotein | 2.7.7.49 | 0.460 | |
| 2q8i | RDC | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial | 2.7.11.2 | 0.460 | |
| 3iqz | H4M | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.460 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.460 | |
| 4fcq | 2N6 | Heat shock protein HSP 90-alpha | / | 0.460 | |
| 1gjv | AGS | [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial | 2.7.11.4 | 0.459 | |
| 2brg | DFY | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.459 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.459 | |
| 4fsw | HK6 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.459 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.458 | |
| 1qnf | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.458 | |
| 2c3k | ABO | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.458 | |
| 3c0g | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.458 | |
| 4eak | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.458 | |
| 4jbq | VX6 | Aurora kinase A | 2.7.11.1 | 0.458 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.457 | |
| 1h1w | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.457 | |
| 1nvs | UCM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.457 | |
| 2ayp | 43A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.457 | |
| 2e8h | SAH | Diphthine synthase | / | 0.457 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.457 | |
| 2ojf | 4PY | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.457 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.457 | |
| 4f07 | FAD | Styrene monooxygenase component 2 | / | 0.457 | |
| 4ia2 | BIV | Vitamin D3 receptor A | / | 0.457 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.456 | |
| 1ol6 | ATP | Aurora kinase A | 2.7.11.1 | 0.456 | |
| 2cch | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
| 2cct | 2E1 | Heat shock protein HSP 90-alpha | / | 0.456 | |
| 2egl | SAH | Diphthine synthase | / | 0.456 | |
| 2f7e | 2EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.456 | |
| 2hkj | RDC | Type 2 DNA topoisomerase 6 subunit B | / | 0.456 | |
| 4ruo | BIV | Vitamin D3 receptor A | / | 0.456 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.455 | |
| 1pkd | UCN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.455 | |
| 1snu | STU | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.455 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.455 | |
| 2hy0 | 306 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.455 | |
| 2i40 | BLZ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.455 | |
| 3say | OFT | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.455 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.455 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 2br1 | PFP | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.454 | |
| 2q7v | FAD | Thioredoxin reductase | / | 0.454 | |
| 2uzd | C85 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 2xht | C0Y | Heat shock protein HSP 90-alpha | / | 0.454 | |
| 3t0z | ATP | Heat shock protein HSP 90-alpha | / | 0.454 | |
| 1xh5 | R68 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.453 | |
| 2cgv | 3B3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.453 | |
| 2ym6 | YM6 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.453 | |
| 2zdx | P4A | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | 2.7.11.2 | 0.453 | |
| 3f7z | 34O | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.453 | |
| 3inv | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.453 | |
| 4acc | 7YG | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.453 | |
| 4ft7 | H3K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.453 | |
| 4fti | H7K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.453 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.453 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.453 | |
| 1nxk | STU | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.452 | |
| 3bwj | ARX | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.452 | |
| 4l9q | 9TP | Serum albumin | / | 0.452 | |
| 4lxj | LAN | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.452 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.452 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.451 | |
| 1eio | GCH | Gastrotropin | / | 0.451 | |
| 1yt0 | ADP | Endoplasmin | / | 0.451 | |
| 2bro | DF2 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.451 | |
| 2egb | SAH | Diphthine synthase | / | 0.451 | |
| 2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.451 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.451 | |
| 2yi7 | BZ8 | Heat shock protein HSP 90-alpha | / | 0.451 | |
| 3aw9 | NAD | NAD-dependent epimerase/dehydratase | / | 0.451 | |
| 3gob | HXX | DdmC | / | 0.451 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.451 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.451 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.451 | |
| 4r21 | STR | Cytochrome P450 family 17 polypeptide 2 | / | 0.451 | |
| 1beu | IPL | Tryptophan synthase alpha chain | / | 0.450 | |
| 1i58 | ACP | Chemotaxis protein CheA | 2.7.13.3 | 0.450 | |
| 1meu | DMP | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
| 1ny3 | ADP | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.450 | |
| 2vo7 | M05 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.450 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 3ruk | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.450 | |
| 1c6z | ROC | Protease | / | 0.449 | |
| 1dhr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.449 | |
| 1sve | I01 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.449 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 2hxl | 422 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.449 | |
| 2q5g | 1FA | Peroxisome proliferator-activated receptor delta | / | 0.449 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.449 | |
| 2ylx | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.449 | |
| 3a0t | ADP | Sensor histidine kinase | / | 0.449 | |
| 4dit | 0KD | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.449 | |
| 5c8w | PCG | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.449 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.448 | |
| 1m13 | HYF | Nuclear receptor subfamily 1 group I member 2 | / | 0.448 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.448 | |
| 2owk | SAH | Diphthine synthase | / | 0.448 | |
| 2owu | SAH | Diphthine synthase | / | 0.448 | |
| 2pch | SAH | Diphthine synthase | / | 0.448 | |
| 2vzm | NRB | Cytochrome P450 monooxygenase PikC | / | 0.448 | |
| 2xne | ASH | Aurora kinase A | 2.7.11.1 | 0.448 | |
| 3aid | ARQ | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 3kb1 | ADP | Iron-sulfur cluster carrier protein | / | 0.448 | |
| 3pgq | GY3 | Acetyl-CoA carboxylase | / | 0.448 | |
| 3v3m | 0EN | Replicase polyprotein 1a | 3.4.19.12 | 0.448 | |
| 4g48 | PZB | Mycocyclosin synthase | 1.14.21.9 | 0.448 | |
| 2c1a | I5S | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.447 | |
| 2ed5 | SAH | Diphthine synthase | / | 0.447 | |
| 2i4z | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 2uzu | L20 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.447 | |
| 3owa | FAD | Acyl-CoA dehydrogenase | / | 0.447 | |
| 4cki | ADN | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.447 | |
| 4duh | RLI | DNA gyrase subunit B | / | 0.447 | |
| 5a9s | NAP | Putative dehydrogenase | / | 0.447 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.446 | |
| 2f7z | 6EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.446 | |
| 2w9s | TOP | Dihydrofolate reductase type 1 from Tn4003 | 1.5.1.3 | 0.446 | |
| 2yec | XQ0 | Heat shock protein HSP 90-alpha | / | 0.446 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.446 | |
| 3tne | RIT | Candidapepsin-1 | 3.4.23.24 | 0.446 | |
| 4ftr | 5HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.446 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.445 | |
| 1stc | STU | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.445 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 2hog | 710 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 2idw | 017 | Protease | / | 0.445 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.445 | |
| 3gub | GUB | Death-associated protein kinase 1 | 2.7.11.1 | 0.445 | |
| 3pj8 | 404 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 3t2y | FAD | Sulfide-quinone reductase | / | 0.445 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.445 | |
| 4h8n | NDP | NADPH-dependent conjugated polyketone reductase C2 | / | 0.445 | |
| 4u9a | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.445 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1nq5 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.444 | |
| 1pjc | NAD | Alanine dehydrogenase | / | 0.444 | |
| 1w2x | RCP | Acetyl-CoA carboxylase | / | 0.444 | |
| 1xh7 | R96 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.444 | |
| 2b53 | D23 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.444 | |
| 3tk3 | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.444 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.444 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.444 | |
| 4fg7 | ATP | Calcium/calmodulin-dependent protein kinase type 1 | 2.7.11.17 | 0.444 | |
| 4ihl | 1F5 | 14-3-3 protein zeta/delta | / | 0.444 | |
| 4iq7 | 1G9 | Mycocyclosin synthase | 1.14.21.9 | 0.444 | |
| 4ktk | KTK | Cytochrome P450 | / | 0.444 | |
| 1cg6 | MTA | S-methyl-5'-thioadenosine phosphorylase | / | 0.443 | |
| 1nqo | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.443 | |
| 2a5k | AZP | Replicase polyprotein 1ab | 3.4.22 | 0.443 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.443 | |
| 2brm | DFZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 2c3l | IDZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 2cx8 | SAH | Ribosomal RNA small subunit methyltransferase E | / | 0.443 | |
| 2e9o | A58 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 2hut | SAH | Diphthine synthase | / | 0.443 | |
| 2o1v | ADP | Endoplasmin | / | 0.443 | |
| 2rhg | IGP | Tryptophan synthase alpha chain | / | 0.443 | |
| 2yjw | YJW | Heat shock protein HSP 90-alpha | / | 0.443 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.443 | |
| 4u97 | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.443 | |
| 4xbo | SAH | tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ | 2.1.1.200 | 0.443 | |
| 4z5w | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.443 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1phe | PIY | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 1u54 | ACP | Activated CDC42 kinase 1 | / | 0.442 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.442 | |
| 1z5a | ADP | Type 2 DNA topoisomerase 6 subunit B | / | 0.442 | |
| 2e16 | SAH | Diphthine synthase | / | 0.442 | |
| 2hfp | NSI | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 2ntv | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.442 | |
| 2w0b | CMW | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.442 | |
| 2wmu | ZYU | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 2ydi | YDI | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 4erw | STU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 4fv7 | E94 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.442 | |
| 4gh2 | HK0 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 1fxs | NAP | GDP-L-fucose synthase | / | 0.441 | |
| 1mp0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.441 | |
| 1oec | AA2 | Fibroblast growth factor receptor 2 | / | 0.441 | |
| 2dv3 | SAH | Diphthine synthase | / | 0.441 | |
| 2p8u | COA | Hydroxymethylglutaryl-CoA synthase, cytoplasmic | 2.3.3.10 | 0.441 | |
| 2pwl | ACP | Fibroblast growth factor receptor 2 | / | 0.441 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.441 | |
| 2rh9 | IGP | Tryptophan synthase alpha chain | / | 0.441 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.441 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.441 | |
| 4djy | 0KR | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4h3y | SAH | tRNA (guanine-N(1)-)-methyltransferase | / | 0.441 | |
| 4hyh | 1AM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.441 | |
| 5eyp | LOC | Tubulin beta chain | / | 0.441 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.440 | |
| 1l4m | NCN | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | 2.4.2.21 | 0.440 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 2p5f | SAH | Diphthine synthase | / | 0.440 | |
| 2vv9 | IM9 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 2y99 | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | 1.3.1.56 | 0.440 | |
| 3cjg | KIM | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.440 | |
| 3she | I85 | MAP kinase-activated protein kinase 3 | 2.7.11.1 | 0.440 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.440 | |
| 4yzc | STU | Serine/threonine-protein kinase/endoribonuclease IRE1 | 2.7.11.1 | 0.440 |