Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2wzwNDPNitroreductase NfnB

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2wzwNDPNitroreductase NfnB/1.000
4loh1SYStimulator of interferon genes protein/0.484
3hl0NADMaleylacetate reductase/0.478
4f5dC2EStimulator of interferon genes protein/0.473
3mj4URMUDP-galactopyranose mutase/0.470
2gevCOKPantothenate kinase2.7.1.330.469
3b4yF42F420-dependent glucose-6-phosphate dehydrogenase/0.469
3qbjNXZDipeptidyl peptidase 4/0.468
5cflC2EStimulator of interferon genes protein/0.468
1ni1HFPProtein farnesyltransferase subunit beta2.5.1.580.466
4jyzATPGlutamine--tRNA ligase6.1.1.180.466
1fapRAPPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.465
1fapRAPSerine/threonine-protein kinase mTOR2.7.11.10.465
1h50FMNPentaerythritol tetranitrate reductase/0.465
1nupNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.465
3af1GDPPantothenate kinase2.7.1.330.464
1h51FMNPentaerythritol tetranitrate reductase/0.463
3eu5GBOProtein farnesyltransferase subunit beta2.5.1.580.463
3fapARDPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.462
3fapARDSerine/threonine-protein kinase mTOR2.7.11.10.462
4c13UMLUDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase/0.462
1ni12C5Protein farnesyltransferase subunit beta2.5.1.580.460
2g1n1IGRenin3.4.23.150.460
4loi1YCStimulator of interferon genes protein/0.459
1udcUFMUDP-glucose 4-epimerase5.1.3.20.458
4drjRAPSerine/threonine-protein kinase mTOR2.7.11.10.458
4drjRAPPeptidyl-prolyl cis-trans isomerase FKBP45.2.1.80.458
4j4nD44Peptidylprolyl isomerase/0.458
2gv8NDPThiol-specific monooxygenase1.14.130.457
3bk2U5PRibonuclease J/0.457
3gf4UPGUDP-galactopyranose mutase5.4.99.90.457
3p62FMNPentaerythritol tetranitrate reductase/0.456
1q0zAKAAclacinomycin methylesterase RdmC3.1.1.950.455
5kwvANPPantothenate synthetase/0.454
1gtrATPGlutamine--tRNA ligase6.1.1.180.453
2g1r3IGRenin3.4.23.150.453
4nv10FXFormyl transferase/0.453
1w34FADFerredoxin--NADP reductase1.18.1.20.452
3inrGDUUDP-galactopyranose mutase5.4.99.90.452
3tr05GPGuanylate kinase/0.451
1x1aSAMC-20 methyltransferase/0.450
2f3rG5PGuanylate kinase2.7.4.80.450
2vetUMPThymidylate synthase/0.450
3enkUPGUDP-glucose 4-epimerase/0.450
3lqsPSZD-alanine aminotransferase2.6.1.210.450
3rbaCODPhosphopantetheine adenylyltransferase/0.450
5cfpC2EStimulator of interferon genes protein/0.450
1lrjUD1UDP-glucose 4-epimerase5.1.3.20.449
2g1s4IGRenin3.4.23.150.449
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.449
2uxoTACHTH-type transcriptional regulator TtgR/0.449
3wqmB29Diterpene synthase3.1.7.80.449
4h0xNADIota toxin component Ia/0.449
1icsFMN12-oxophytodienoate reductase 11.3.1.420.448
3f03FMNPentaerythritol tetranitrate reductase/0.448
3fr5I4AFatty acid-binding protein, adipocyte/0.448
4hmz18TdTDP-4-dehydro-6-deoxyglucose 3-epimerase5.1.3.270.448
4yaoFMNNADPH--cytochrome P450 reductase/0.448
4yp12BAStimulator of interferon genes protein/0.448
1s63778Protein farnesyltransferase subunit beta2.5.1.580.447
4gv4MEJPoly [ADP-ribose] polymerase 32.4.2.300.447
1ld7U66Protein farnesyltransferase subunit beta2.5.1.580.446
1s4oGDPGlycolipid 2-alpha-mannosyltransferase/0.446
2iyfERYOleandomycin glycosyltransferase2.4.10.446
1eq2ADQADP-L-glycero-D-manno-heptose-6-epimerase/0.445
1kp3ATPArgininosuccinate synthase6.3.4.50.445
1n2hPAJPantothenate synthetase6.3.2.10.445
1qrsATPGlutamine--tRNA ligase6.1.1.180.445
2g226IGRenin3.4.23.150.445
3ukfGDUUDP-galactopyranose mutase/0.445
3hl4CDCCholine-phosphate cytidylyltransferase A/0.444
3opmLUIDipeptidyl peptidase 4/0.444
3p67FMNPentaerythritol tetranitrate reductase/0.444
4bfvZVVPantothenate kinase2.7.1.330.444
4gz612VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.444
4q71FADBifunctional protein PutA/0.444
1tcoFK5Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.443
1tcoFK5Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform3.1.3.160.443
1h63FMNPentaerythritol tetranitrate reductase/0.442
1udbUFGUDP-glucose 4-epimerase5.1.3.20.442
3e34ED1Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.442
3e34ED1Protein farnesyltransferase subunit beta2.5.1.580.442
3kybFMNUDP-galactopyranose mutase5.4.99.90.442
3s87ADPRibonucleoside-diphosphate reductase large chain 11.17.4.10.442
4lutDCSAlanine racemase/0.442
1ib0NADNADH-cytochrome b5 reductase 31.6.2.20.441
1n95HFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.441
1n95HFPProtein farnesyltransferase subunit beta2.5.1.580.441
1nl4HFPProtein farnesyltransferase subunit beta2.5.1.580.441
2g247IGRenin3.4.23.150.441
2qs3UBEGlutamate receptor ionotropic, kainate 1/0.441
2rdn1PL1-deoxypentalenic acid 11-beta-hydroxylase1.14.11.350.441
4jayNAPUDP-N-acetylenolpyruvoylglucosamine reductase/0.441
1bim0QBRenin3.4.23.150.440
2hs8FMN12-oxophytodienoate reductase 31.3.1.420.440
2vyqFADFerredoxin--NADP reductase1.18.1.20.440
3h3qH13Collagen type IV alpha-3-binding protein/0.440
3h3t16HCollagen type IV alpha-3-binding protein/0.440
3q43D66M1 family aminopeptidase3.4.110.440
4egbNADdTDP-glucose 4,6-dehydratase/0.440
4twrNADNAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase/0.440
5czySAMEukaryotic huntingtin interacting protein B/0.440