sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2wu5 | CBE | Succinate dehydrogenase iron-sulfur subunit | 1.3.5.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2wu5 | CBE | Succinate dehydrogenase iron-sulfur subunit | 1.3.5.1 | 1.000 | |
| 2wu5 | CBE | Succinate dehydrogenase cytochrome b556 subunit | / | 1.000 | |
| 2wp9 | CBE | Succinate dehydrogenase iron-sulfur subunit | 1.3.5.1 | 0.629 | |
| 2wp9 | CBE | Succinate dehydrogenase cytochrome b556 subunit | / | 0.629 | |
| 2wu2 | CBE | Succinate dehydrogenase iron-sulfur subunit | 1.3.5.1 | 0.610 | |
| 2wu2 | CBE | Succinate dehydrogenase cytochrome b556 subunit | / | 0.610 | |
| 2wdq | CBE | Succinate dehydrogenase iron-sulfur subunit | 1.3.5.1 | 0.580 | |
| 2wdq | CBE | Succinate dehydrogenase cytochrome b556 subunit | / | 0.580 | |
| 1nen | DNT | Succinate dehydrogenase iron-sulfur subunit | 1.3.5.1 | 0.546 | |
| 1nen | DNT | Succinate dehydrogenase cytochrome b556 subunit | / | 0.546 | |
| 3nga | 3NG | Casein kinase II subunit alpha | 2.7.11.1 | 0.526 | |
| 2dxd | ANP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.520 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.512 | |
| 3q8u | ADP | Nucleoside diphosphate kinase | / | 0.509 | |
| 1zoy | UQ1 | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | 1.3.5.1 | 0.507 | |
| 1zoy | UQ1 | Succinate dehydrogenase cytochrome b560 subunit, mitochondrial | / | 0.507 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.505 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.500 | |
| 1d3h | A26 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.499 | |
| 5c3j | UQ1 | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | / | 0.498 | |
| 5c3j | UQ1 | Succinate dehydrogenase cytochrome b560 | / | 0.498 | |
| 3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.497 | |
| 3owk | 18E | Casein kinase II subunit alpha | 2.7.11.1 | 0.497 | |
| 5iqb | GNP | Bifunctional AAC/APH | 2.3.1 | 0.496 | |
| 2fbw | CBE | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | 1.3.5.1 | 0.495 | |
| 2fbw | CBE | Succinate dehydrogenase cytochrome b, large subunit | / | 0.495 | |
| 4y9l | FAD | Acyl-CoA dehydrogenase family member 11 | / | 0.494 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.492 | |
| 4bl5 | GFB | GDP-L-fucose synthase | 1.1.1.271 | 0.492 | |
| 3i5x | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.491 | |
| 4ytn | FD8 | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | / | 0.491 | |
| 4ytn | FD8 | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial | / | 0.491 | |
| 4ytn | FD8 | Succinate dehydrogenase cytochrome b560 | / | 0.491 | |
| 5dju | FMN | NPH1-2 | / | 0.491 | |
| 2bu7 | TF3 | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.489 | |
| 1nhk | CMP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.488 | |
| 3vrb | FTN | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | / | 0.488 | |
| 3vrb | FTN | Cytochrome b-large subunit | / | 0.488 | |
| 3k7m | FAD | 6-hydroxy-L-nicotine oxidase | / | 0.487 | |
| 1p4m | ADP | Riboflavin kinase | 2.7.1.26 | 0.486 | |
| 2hc4 | VDX | Vitamin D3 receptor A | / | 0.485 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.485 | |
| 1fcy | 564 | Retinoic acid receptor gamma | / | 0.484 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.484 | |
| 2tsc | CB3 | Thymidylate synthase | / | 0.483 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.483 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.482 | |
| 3axw | TID | Casein kinase II subunit alpha | 2.7.11.1 | 0.482 | |
| 4o7u | THF | Thymidylate synthase | / | 0.481 | |
| 3vr8 | RQX | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | / | 0.480 | |
| 3vr8 | RQX | Cytochrome b-large subunit | / | 0.480 | |
| 4b5o | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.480 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.480 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.479 | |
| 4g2i | 0VQ | Vitamin D3 receptor | / | 0.479 | |
| 5cu6 | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.479 | |
| 1j39 | UPG | DNA beta-glucosyltransferase | / | 0.478 | |
| 1zs6 | ADP | Nucleoside diphosphate kinase 3 | 2.7.4.6 | 0.478 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.477 | |
| 3eej | 53R | Uncharacterized protein | / | 0.477 | |
| 3x1z | GNP | Ras-related protein Rap-1b | / | 0.477 | |
| 4m9a | FDA | Acyl-CoA dehydrogenase | / | 0.477 | |
| 1fdu | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.476 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.476 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.476 | |
| 4grb | 0XG | Casein kinase II subunit alpha | 2.7.11.1 | 0.476 | |
| 4i4b | 1CV | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.476 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.476 | |
| 4l8g | GDP | GTPase KRas | / | 0.476 | |
| 4rup | H97 | Vitamin D3 receptor A | / | 0.476 | |
| 2bts | U32 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.475 | |
| 2r0p | K2C | Putative FAD-monooxygenase | / | 0.475 | |
| 3eem | 53V | Uncharacterized protein | / | 0.475 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.475 | |
| 3up3 | XCA | aceDAF-12 | / | 0.475 | |
| 4o2r | GDP | GTP-binding protein Rheb | / | 0.475 | |
| 4zas | TYD | CalS13 | / | 0.475 | |
| 5djt | FMN | NPH1-2 | / | 0.475 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
| 4ldj | GDP | GTPase KRas | / | 0.474 | |
| 3ge1 | ADP | Glycerol kinase | / | 0.473 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.473 | |
| 4h9t | HL4 | Phosphotriesterase | / | 0.473 | |
| 4rrv | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.473 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.472 | |
| 1uyk | PUX | Heat shock protein HSP 90-alpha | / | 0.472 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.472 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.472 | |
| 2kce | D16 | Thymidylate synthase | / | 0.472 | |
| 2o4j | VD4 | Vitamin D3 receptor | / | 0.472 | |
| 2xpu | TDC | Tetracycline repressor protein class D | / | 0.472 | |
| 3pd4 | A3G | Threonine--tRNA ligase | 6.1.1.3 | 0.472 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.472 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.472 | |
| 4g20 | 484 | Vitamin D3 receptor A | / | 0.472 | |
| 4hw3 | 19G | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.472 | |
| 4lv6 | GDP | GTPase KRas | / | 0.472 | |
| 5iqi | GNP | Bifunctional AAC/APH | 2.3.1 | 0.472 | |
| 1jmh | UMP | Thymidylate synthase | / | 0.471 | |
| 2fpc | SCG | Strictosidine synthase | 4.3.3.2 | 0.471 | |
| 4g0n | GNP | GTPase HRas | / | 0.471 | |
| 5iqd | GNP | Bifunctional AAC/APH | 2.3.1 | 0.471 | |
| 1dd6 | MCI | Metallo-beta-lactamase type 2 | / | 0.470 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
| 1zp9 | ATP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.470 | |
| 3m13 | FAD | Monomeric sarcosine oxidase | 1.5.3.1 | 0.470 | |
| 4b2w | BZ0 | Glucose-1-phosphate thymidylyltransferase | / | 0.470 | |
| 4d0l | GSP | Ras-related protein Rab-11A | / | 0.470 | |
| 2ch6 | ADP | N-acetyl-D-glucosamine kinase | 2.7.1.59 | 0.469 | |
| 4dve | BTN | Biotin transporter BioY | / | 0.469 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.469 | |
| 4nm9 | FAD | Bifunctional protein PutA | / | 0.469 | |
| 4tq9 | GDP | GTPase KRas | / | 0.469 | |
| 4z24 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.469 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.468 | |
| 2qoq | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.468 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.468 | |
| 3sqw | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.468 | |
| 4mv4 | ACP | Biotin carboxylase | 6.3.4.14 | 0.468 | |
| 1g6o | ADP | Cag alpha | / | 0.467 | |
| 1yu9 | GNP | Ras-related protein Rab-4A | / | 0.467 | |
| 2hb8 | MVD | Vitamin D3 receptor | / | 0.467 | |
| 2o4r | VD5 | Vitamin D3 receptor | / | 0.467 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.467 | |
| 3at3 | ATK | Casein kinase II subunit alpha | 2.7.11.1 | 0.467 | |
| 3at4 | CCK | Casein kinase II subunit alpha | 2.7.11.1 | 0.467 | |
| 3r6p | A8S | Abscisic acid receptor PYL10 | / | 0.467 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.467 | |
| 1eji | THF | Serine hydroxymethyltransferase, cytosolic | / | 0.466 | |
| 3nmn | PYV | Abscisic acid receptor PYL1 | / | 0.466 | |
| 3ruv | ANP | Chaperonin | / | 0.466 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.466 | |
| 1osv | CHC | Bile acid receptor | / | 0.465 | |
| 1vza | UMP | Thymidylate synthase | / | 0.465 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.465 | |
| 3ihg | VAK | Aklavinone 12-hydroxylase RdmE | / | 0.465 | |
| 4dsb | A8S | Abscisic acid receptor PYL3 | / | 0.465 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.465 | |
| 5efw | FMN | NPH1-1 | / | 0.465 | |
| 1fdw | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.464 | |
| 1rxh | BNI | Streptavidin | / | 0.464 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.464 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.464 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.464 | |
| 4g2f | C07 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.464 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.463 | |
| 1f5f | DHT | Sex hormone-binding globulin | / | 0.463 | |
| 1g28 | FMN | PHY3 | / | 0.463 | |
| 1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.463 | |
| 1ngs | TPP | Transketolase 1 | 2.2.1.1 | 0.463 | |
| 1x7h | NDP | Putative ketoacyl reductase | 1.3.1 | 0.463 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.463 | |
| 2dxe | GDP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.463 | |
| 2has | C3O | Vitamin D3 receptor | / | 0.463 | |
| 2qd5 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.463 | |
| 3qlx | QLR | Uncharacterized protein | / | 0.463 | |
| 3sgt | P09 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | / | 0.463 | |
| 4bb4 | 32W | Ephrin type-B receptor 4 | 2.7.10.1 | 0.463 | |
| 4rrg | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.463 | |
| 4rrx | LUR | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.463 | |
| 1rkg | VD1 | Vitamin D3 receptor | / | 0.462 | |
| 2ayl | FLP | Prostaglandin G/H synthase 1 | 1.14.99.1 | 0.462 | |
| 2w2l | NAD | D-mandelate dehydrogenase | / | 0.462 | |
| 2zlc | VDX | Vitamin D3 receptor | / | 0.462 | |
| 3fmo | ADP | ATP-dependent RNA helicase DDX19B | 3.6.4.13 | 0.462 | |
| 3k9l | GNP | GTPase HRas | / | 0.462 | |
| 3t3r | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.462 | |
| 3uyk | 0CX | Probable NDP-rhamnosyltransferase | / | 0.462 | |
| 3zc5 | W9Z | Hepatocyte growth factor receptor | 2.7.10.1 | 0.462 | |
| 4d03 | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.462 | |
| 4isk | 1JY | Thymidylate synthase | / | 0.462 | |
| 4rrr | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.462 | |
| 4xw4 | ANP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.462 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 1ot7 | IU5 | Bile acid receptor | / | 0.461 | |
| 1q6t | 600 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.461 | |
| 2abj | CBC | Branched-chain-amino-acid aminotransferase, cytosolic | 2.6.1.42 | 0.461 | |
| 2acl | L05 | Oxysterols receptor LXR-alpha | / | 0.461 | |
| 2c3q | GTX | Glutathione S-transferase theta-1 | 2.5.1.18 | 0.461 | |
| 2c5y | MTW | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.461 | |
| 2fhn | BNI | Avidin-related protein 4/5 | / | 0.461 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.461 | |
| 3ofm | 4B0 | Casein kinase II subunit alpha' | 2.7.11.1 | 0.461 | |
| 4fhi | 0S4 | Vitamin D3 receptor A | / | 0.461 | |
| 4g2h | 0VQ | Vitamin D3 receptor A | / | 0.461 | |
| 4kwh | NAP | Reductase homolog | / | 0.461 | |
| 4tx9 | AMZ | Phosphoribosyl isomerase A | / | 0.461 | |
| 1kzi | THG | Thymidylate synthase | / | 0.460 | |
| 1n4p | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.460 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.460 | |
| 1q3q | ANP | Thermosome subunit alpha | / | 0.460 | |
| 2j5s | KTA | Alr4455 protein | / | 0.460 | |
| 3b03 | VNR | Isopentenyl-diphosphate delta-isomerase | / | 0.460 | |
| 3biy | 01K | Histone acetyltransferase p300 | / | 0.460 | |
| 3ddw | 055 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.460 | |
| 3o96 | IQO | RAC-alpha serine/threonine-protein kinase | 2.7.11.1 | 0.460 | |
| 3w0i | O11 | Vitamin D3 receptor | / | 0.460 | |
| 3x2w | ATP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.460 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.460 | |
| 4dk7 | 0KS | Oxysterols receptor LXR-beta | / | 0.460 | |
| 4l1x | STR | Aldo-keto reductase family 1 member C2 | / | 0.460 | |
| 4n5n | NAP | Acetoacetyl-CoA reductase | 1.1.1.36 | 0.460 | |
| 4nmb | FAD | Bifunctional protein PutA | / | 0.460 | |
| 4xg1 | LLP | Diaminopimelate decarboxylase | / | 0.460 | |
| 5ebu | FMN | Lactate oxidase | / | 0.460 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.459 | |
| 2i0y | 5CN | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.459 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.459 | |
| 2o1x | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.459 | |
| 3ngu | ADP | Nucleoside diphosphate kinase | / | 0.459 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.459 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.459 | |
| 3oiu | GNP | GTPase HRas | / | 0.459 | |
| 4fi1 | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.459 | |
| 4n3c | UD1 | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.459 | |
| 4u9y | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.459 | |
| 1fm7 | DFV | Chalcone--flavonone isomerase 1 | 5.5.1.6 | 0.458 | |
| 1s19 | MC9 | Vitamin D3 receptor | / | 0.458 | |
| 2fg5 | GNP | Ras-related protein Rab-31 | / | 0.458 | |
| 2itw | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.458 | |
| 2v1a | FMN | NPH1-1 | / | 0.458 | |
| 2v3a | FAD | Rubredoxin-NAD(+) reductase | 1.18.1.1 | 0.458 | |
| 3vrv | YSD | Vitamin D3 receptor | / | 0.458 | |
| 3vt3 | VDX | Vitamin D3 receptor | / | 0.458 | |
| 4dsn | GCP | GTPase KRas | / | 0.458 | |
| 4hr2 | ADP | Nucleoside diphosphate kinase | / | 0.458 | |
| 4u07 | ATP | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.458 | |
| 4ymg | SAM | Putative SAM-dependent O-methyltranferase | / | 0.458 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.457 | |
| 1exa | 394 | Retinoic acid receptor gamma | / | 0.457 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.457 | |
| 2bun | FAD | AppA protein | / | 0.457 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.457 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.457 | |
| 2p9g | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.457 | |
| 2vqd | AP2 | Biotin carboxylase | 6.3.4.14 | 0.457 | |
| 3c13 | EMO | Casein kinase II subunit alpha | 2.7.11.1 | 0.457 | |
| 3otu | BI4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.457 | |
| 3pxv | FMN | Nitroreductase | / | 0.457 | |
| 3s3v | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 3vt4 | 5YI | Vitamin D3 receptor | / | 0.457 | |
| 4bhw | 01K | Histone acetyltransferase p300 | / | 0.457 | |
| 4bva | T3 | Ketimine reductase mu-crystallin | 1.5.1.25 | 0.457 | |
| 4zzj | CNA | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.457 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.457 | |
| 1crb | RTL | Retinol-binding protein 1 | / | 0.456 | |
| 1rj6 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.456 | |
| 1rk3 | VDX | Vitamin D3 receptor | / | 0.456 | |
| 1tkb | N1T | Transketolase 1 | 2.2.1.1 | 0.456 | |
| 2b9i | ADP | Mitogen-activated protein kinase FUS3 | 2.7.11.24 | 0.456 | |
| 2i0z | FAD | NAD(FAD)-utilizing dehydrogenases | / | 0.456 | |
| 2ohv | NHL | Glutamate racemase | / | 0.456 | |
| 2p2l | GDP | Ras-related C3 botulinum toxin substrate 1 | / | 0.456 | |
| 3g8d | ADP | Biotin carboxylase | 6.3.4.14 | 0.456 | |
| 3gdp | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.456 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.456 | |
| 3qtz | X42 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
| 4alh | A9P | Bromodomain-containing protein 2 | / | 0.456 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 4o0r | X4Z | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.456 | |
| 4qxa | GTP | Ras-related protein Rab-9A | / | 0.456 | |
| 5h8t | RTL | Retinol-binding protein 1 | / | 0.456 | |
| 2a0y | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.455 | |
| 2b7a | IZA | Tyrosine-protein kinase JAK2 | / | 0.455 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.455 | |
| 2i0v | 6C3 | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.455 | |
| 2v0u | FMN | NPH1-1 | / | 0.455 | |
| 2xc3 | RT8 | Steroid C26-monooxygenase | 1.14.13.141 | 0.455 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.455 | |
| 3sf6 | FDA | Glutaryl-CoA dehydrogenase | / | 0.455 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.455 | |
| 3uim | ANP | BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1 | 2.7.10.1 | 0.455 | |
| 4bgb | ADP | Predicted molecular chaperone distantly related to HSP70-fold metalloproteases | / | 0.455 | |
| 4cid | ANP | EH domain-containing protein 2 | / | 0.455 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.455 | |
| 4epw | GDP | GTPase KRas | / | 0.455 | |
| 4fog | C2F | Thymidylate synthase ThyA | / | 0.455 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.455 | |
| 4xx9 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.455 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.454 | |
| 2g8a | UMP | Thymidylate synthase | / | 0.454 | |
| 2oby | NAP | Quinone oxidoreductase PIG3 | 1 | 0.454 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.454 | |
| 2xtz | GSP | Guanine nucleotide-binding protein alpha-1 subunit | / | 0.454 | |
| 3cph | GDP | Ras-related protein SEC4 | / | 0.454 | |
| 3eld | SFG | Methyltransferase | / | 0.454 | |
| 3kbo | NDP | Glyoxylate/hydroxypyruvate reductase A | / | 0.454 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.454 | |
| 3pyz | ANP | Dihydrofolate synthase/folylpolyglutamate synthase | / | 0.454 | |
| 3qvp | FAD | Glucose oxidase | 1.1.3.4 | 0.454 | |
| 4fjz | 4FJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.454 | |
| 4fm5 | DF0 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.454 | |
| 4hkf | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.454 | |
| 4if5 | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.454 | |
| 4jqe | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.454 | |
| 4lv5 | ADP | Rhoptry protein 5B | / | 0.454 | |
| 4ql3 | GDP | GTPase KRas | / | 0.454 | |
| 4ubv | COA | Steroid 3-ketoacyl-CoA thiolase | / | 0.454 | |
| 4z28 | BTN | Hoefavidin | / | 0.454 | |
| 1avd | BTN | Avidin | / | 0.453 | |
| 1f4g | TP4 | Thymidylate synthase | / | 0.453 | |
| 1mcz | TDP | Benzoylformate decarboxylase | 4.1.1.7 | 0.453 | |
| 1n1e | NDE | Glycerol-3-phosphate dehydrogenase [NAD(+)], glycosomal | 1.1.1.8 | 0.453 | |
| 1nue | GDP | Nucleoside diphosphate kinase B | 2.7.4.6 | 0.453 | |
| 1piw | NAP | NADP-dependent alcohol dehydrogenase 6 | 1.1.1.2 | 0.453 | |
| 1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.453 | |
| 2f02 | ATP | Tagatose-6-phosphate kinase | / | 0.453 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.453 | |
| 2jfh | LK1 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.453 | |
| 2qo7 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.453 | |
| 2zb4 | 5OP | Prostaglandin reductase 2 | 1.3.1.48 | 0.453 | |
| 3n8w | FLP | Prostaglandin G/H synthase 1 | 1.14.99.1 | 0.453 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.453 | |
| 3uu1 | 14B | Anthranilate phosphoribosyltransferase | / | 0.453 | |
| 4epx | GDP | GTPase KRas | / | 0.453 | |
| 4gll | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.453 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.453 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.453 | |
| 4ubu | COA | Steroid 3-ketoacyl-CoA thiolase | / | 0.453 | |
| 4xiw | AZM | Carbonic anhydrase, alpha type | / | 0.453 | |
| 4ydu | ADP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.453 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.453 | |
| 1kqu | BR4 | Phospholipase A2, membrane associated | / | 0.452 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1mrq | STR | Aldo-keto reductase family 1 member C1 | / | 0.452 | |
| 1orr | CDP | CDP-paratose 2-epimerase | / | 0.452 | |
| 1tou | B1V | Fatty acid-binding protein, adipocyte | / | 0.452 | |
| 1zd9 | GDP | ADP-ribosylation factor-like protein 8A | / | 0.452 | |
| 2q4w | FAD | Cytokinin dehydrogenase 7 | 1.5.99.12 | 0.452 | |
| 3apf | BMW | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.452 | |
| 3ely | SAH | Methyltransferase | / | 0.452 | |
| 3hav | ATP | Aminoglycoside phosphotransferase | / | 0.452 | |
| 3kko | GNP | Ras-related protein M-Ras | / | 0.452 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.452 | |
| 3r96 | ACO | MccE protein | / | 0.452 | |
| 3rus | ADP | Chaperonin | / | 0.452 | |
| 3ujl | A8S | Abscisic acid receptor PYL2 | / | 0.452 | |
| 3upt | TPP | Transketolase | / | 0.452 | |
| 3v49 | PK0 | Androgen receptor | / | 0.452 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.452 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.452 | |
| 4m69 | ANP | Receptor-interacting serine/threonine-protein kinase 3 | 2.7.11.1 | 0.452 | |
| 4nhk | PD2 | Prolyl 3,4-dihydroxylase TPA1 | 1.14.11 | 0.452 | |
| 4q02 | GDP | GTPase KRas | / | 0.452 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.451 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1f0x | FAD | D-lactate dehydrogenase | 1.1.1.28 | 0.451 | |
| 1ib0 | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.451 | |
| 1kt8 | ILP | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.451 | |
| 1ot7 | CHC | Bile acid receptor | / | 0.451 | |
| 1psd | NAD | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.451 | |
| 2bxm | IMN | Serum albumin | / | 0.451 | |
| 2czf | XMP | Orotidine 5'-phosphate decarboxylase | 4.1.1.23 | 0.451 | |
| 2e9n | 76A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.451 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.451 | |
| 2j9g | ANP | Biotin carboxylase | 6.3.4.14 | 0.451 | |
| 2jfz | 003 | Glutamate racemase | / | 0.451 | |
| 2rgg | GNP | GTPase HRas | / | 0.451 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 4a0s | CO8 | Octenoyl-CoA reductase/carboxylase | / | 0.451 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.451 | |
| 4h6p | FMN | Chromate reductase | / | 0.451 | |
| 5hbs | RTL | Retinol-binding protein 1 | / | 0.451 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.450 | |
| 1fds | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.450 | |
| 1fml | RTL | Retinol dehydratase | / | 0.450 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1unh | IXM | Cyclin-dependent-like kinase 5 | 2.7.11.1 | 0.450 | |
| 1wkl | ATP | Nucleoside diphosphate kinase | / | 0.450 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.450 | |
| 3b9l | AZZ | Serum albumin | / | 0.450 | |
| 3n5y | XFL | Nitric oxide synthase, brain | 1.14.13.39 | 0.450 | |
| 3w5r | LOA | Vitamin D3 receptor | / | 0.450 | |
| 4f70 | 0ST | Cyclin-dependent kinase 8 | 2.7.11.22 | 0.450 | |
| 4gs4 | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.450 | |
| 4iaf | ADP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.450 | |
| 4j0v | 1H7 | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 4o1m | NAD | Enoyl-acyl carrier reductase | / | 0.450 | |
| 5dx8 | SFG | Histone-arginine methyltransferase CARM1 | / | 0.450 | |
| 5iqa | GNP | Bifunctional AAC/APH | 2.3.1 | 0.450 | |
| 5iqh | GNP | Bifunctional AAC/APH | 2.3.1 | 0.450 | |
| 1dr5 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1e8x | ATP | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.449 | |
| 1eyy | NAP | NADP-dependent fatty aldehyde dehydrogenase | 1.2.1.4 | 0.449 | |
| 1f4f | TP3 | Thymidylate synthase | / | 0.449 | |
| 1ikg | REX | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.449 | |
| 1p0h | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.449 | |
| 1tu3 | GNP | Ras-related protein Rab-5A | / | 0.449 | |
| 1z6t | ADP | Apoptotic protease-activating factor 1 | / | 0.449 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.449 | |
| 2og8 | 1N8 | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.449 | |
| 2wd9 | IBP | Acyl-coenzyme A synthetase ACSM2A, mitochondrial | 6.2.1.2 | 0.449 | |
| 2zl9 | VDA | Vitamin D3 receptor | / | 0.449 | |
| 3ggs | 2FD | Purine nucleoside phosphorylase | 2.4.2.1 | 0.449 | |
| 3hx4 | ANP | Calmodulin-domain protein kinase 1 | / | 0.449 | |
| 3up0 | D7S | aceDAF-12 | / | 0.449 | |
| 3vjo | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.449 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.449 | |
| 4bls | APC | NTPase P4 | / | 0.449 | |
| 4fad | 0TB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.449 | |
| 4g67 | SAH | Uncharacterized ACR, COG1565 superfamily | / | 0.449 | |
| 4ia2 | BIV | Vitamin D3 receptor A | / | 0.449 | |
| 4jau | ADP | Sensor histidine kinase | / | 0.449 | |
| 4m11 | MXM | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.449 | |
| 4pzr | COA | Histone acetyltransferase p300 | / | 0.449 | |
| 4ure | 1PS | Cyclohexanol dehydrogenase | / | 0.449 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.449 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 1f4e | TPR | Thymidylate synthase | / | 0.448 | |
| 1j4j | ACO | Acetyltransferase | 2.3.1 | 0.448 | |
| 1mh1 | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.448 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 1zth | ADP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.448 | |
| 2c7q | SAH | Modification methylase HhaI | 2.1.1.37 | 0.448 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.448 | |
| 2ob0 | ACO | N-alpha-acetyltransferase 50 | / | 0.448 | |
| 2x6t | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.448 | |
| 3bgx | MEF | Thymidylate synthase | / | 0.448 | |
| 3gkj | HC3 | Niemann-Pick C1 protein | / | 0.448 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.448 | |
| 3qcz | ANP | Dihydrofolate synthase/folylpolyglutamate synthase | / | 0.448 | |
| 3qrw | NDP | Putative ketoacyl reductase | 1.3.1 | 0.448 | |
| 3w6u | NAP | 6-phosphogluconate dehydrogenase, NAD-binding protein | / | 0.448 | |
| 4b8z | GDP | GDP-L-fucose synthase | 1.1.1.271 | 0.448 | |
| 4cf7 | ADP | Adenylate kinase | / | 0.448 | |
| 4cje | Q31 | Integrase | / | 0.448 | |
| 4dh5 | ADP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.448 | |
| 4plp | NAD | Homospermidine synthase | 2.5.1.44 | 0.448 | |
| 5ack | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.448 | |
| 5czy | SAM | Eukaryotic huntingtin interacting protein B | / | 0.448 | |
| 1ie9 | VDX | Vitamin D3 receptor | / | 0.447 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.447 | |
| 1om1 | IQA | Casein kinase II subunit alpha | 2.7.11.1 | 0.447 | |
| 1q24 | ATP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.447 | |
| 2fhl | BNI | Avidin-related protein 4/5 | / | 0.447 | |
| 2pg0 | FAD | Acyl-CoA dehydrogenase | / | 0.447 | |
| 3dds | 26B | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.447 | |
| 3ews | ADP | ATP-dependent RNA helicase DDX19B | 3.6.4.13 | 0.447 | |
| 3gbu | ATP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.447 | |
| 3jpu | TY4 | Transcriptional activator protein LasR | / | 0.447 | |
| 3lbn | GNP | GTPase HRas | / | 0.447 | |
| 3up5 | NAP | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.447 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.447 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.447 | |
| 4ajm | 3A6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.447 | |
| 4b4b | GJB | Glucose-1-phosphate thymidylyltransferase | / | 0.447 | |
| 4dgn | LU2 | Casein kinase II subunit alpha | 2.7.11.1 | 0.447 | |
| 4emd | C5P | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.447 | |
| 4ez8 | DHF | Thymidylate synthase | 2.1.1.45 | 0.447 | |
| 4fqs | LYA | Thymidylate synthase ThyA | / | 0.447 | |
| 4fuy | EK2 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.447 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.447 | |
| 5iqe | GNP | Bifunctional AAC/APH | 2.3.1 | 0.447 | |
| 4ej4 | EJ4 | Delta-type opioid receptor | / | 0.447 | |
| 1fdt | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.446 | |
| 1jnz | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.446 | |
| 1opb | RET | Retinol-binding protein 2 | / | 0.446 | |
| 1swt | BTN | Streptavidin | / | 0.446 | |
| 1sxj | ADP | Replication factor C subunit 5 | / | 0.446 | |
| 1tow | CRZ | Fatty acid-binding protein, adipocyte | / | 0.446 | |
| 1w7k | ADP | Dihydrofolate synthase/folylpolyglutamate synthase | 6.3.2.12 | 0.446 | |
| 1y9d | TPP | Pyruvate oxidase | 1.2.3.3 | 0.446 | |
| 1zc3 | GNP | Ras-related protein Ral-A | / | 0.446 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.446 | |
| 2an9 | GDP | Guanylate kinase | 2.7.4.8 | 0.446 | |
| 2e9d | B76 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.446 | |
| 2gvc | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.446 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.446 | |
| 2r4t | ADP | Glycogen synthase | 2.4.1.21 | 0.446 | |
| 2uyw | BTN | Avd protein | / | 0.446 | |
| 2v59 | LZK | Biotin carboxylase | 6.3.4.14 | 0.446 | |
| 2wkm | PFY | Hepatocyte growth factor receptor | 2.7.10.1 | 0.446 | |
| 2yoz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.446 | |
| 3m12 | FAD | Monomeric sarcosine oxidase | 1.5.3.1 | 0.446 | |
| 3uoy | NAP | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.446 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.446 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.446 | |
| 3wth | IM4 | Acetylcholine-binding protein | / | 0.446 | |
| 4ajd | F04 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.446 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 0.446 | |
| 4e9a | QAP | Peptide deformylase | / | 0.446 | |
| 4eiq | KCT | Putative FAD-monooxygenase | / | 0.446 | |
| 4mq1 | 2C3 | Dual specificity tyrosine-phosphorylation-regulated kinase 1A | 2.7.12.1 | 0.446 | |
| 4mwh | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.446 | |
| 4q03 | GDP | GTPase KRas | / | 0.446 | |
| 4rrl | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.446 | |
| 4xvr | GNP | GTPase HRas | / | 0.446 | |
| 5cae | COA | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial | 6.2.1.4 | 0.446 | |
| 1ao0 | 5GP | Amidophosphoribosyltransferase | / | 0.445 | |
| 1be4 | PCG | Nucleoside diphosphate kinase A 2 | 2.7.4.6 | 0.445 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.445 | |
| 1u1g | BBB | Uridine phosphorylase | 2.4.2.3 | 0.445 | |
| 1zio | AP5 | Adenylate kinase | / | 0.445 | |
| 2bfr | ADP | [Protein ADP-ribosylglutamate] hydrolase AF_1521 | 3.2.2 | 0.445 | |
| 2ix5 | FAD | Acyl-coenzyme A oxidase 4, peroxisomal | 1.3.3.6 | 0.445 | |
| 2ooy | ATP | 5'-AMP-activated protein kinase subunit gamma | / | 0.445 | |
| 2r5n | TPP | Transketolase 1 | / | 0.445 | |
| 2rir | NAP | Dipicolinate synthase subunit A | / | 0.445 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 2w98 | P1Z | Prostaglandin reductase 2 | 1.3.1.48 | 0.445 | |
| 2ym1 | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.445 | |
| 3eof | FMN | Putative oxidase | / | 0.445 | |
| 3g1o | RF1 | HTH-type transcriptional regulator EthR | / | 0.445 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.445 | |
| 3img | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.445 | |
| 3rwp | ABQ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.445 | |
| 3sjz | GNP | Translation initiation factor 2 subunit gamma | / | 0.445 | |
| 3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.445 | |
| 3tp0 | FO5 | HTH-type transcriptional regulator EthR | / | 0.445 | |
| 3u8h | BHP | Phospholipase A2, membrane associated | / | 0.445 | |
| 3uba | HC4 | Lactoperoxidase | 1.11.1.7 | 0.445 | |
| 3w0j | T08 | Vitamin D3 receptor | / | 0.445 | |
| 3wnz | ADP | Alanine--anticapsin ligase | / | 0.445 | |
| 4eep | FMN | Phototropin-2 | 2.7.11.1 | 0.445 | |
| 4fg8 | ATP | Calcium/calmodulin-dependent protein kinase type 1 | 2.7.11.17 | 0.445 | |
| 4hpt | ANP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.445 | |
| 4ks7 | X4Z | Serine/threonine-protein kinase PAK 6 | 2.7.11.1 | 0.445 | |
| 4oty | LUR | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.445 | |
| 4u0s | ADP | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.445 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.445 | |
| 1e26 | GPB | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1klk | PMD | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.444 | |
| 1q3s | ADP | Thermosome subunit alpha | / | 0.444 | |
| 1qax | HMG | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.444 | |
| 1udt | VIA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.444 | |
| 1uyf | PU1 | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.444 | |
| 2ilt | NN1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.444 | |
| 2lba | CHO | Fatty acid binding protein 6 | / | 0.444 | |
| 2rtm | IMI | Streptavidin | / | 0.444 | |
| 2uyy | NA7 | Putative oxidoreductase GLYR1 | 1 | 0.444 | |
| 2vf0 | F89 | Thymidylate synthase | / | 0.444 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.444 | |
| 2xvv | 9DN | Serum albumin | / | 0.444 | |
| 3bi6 | 396 | Wee1-like protein kinase | 2.7.10.2 | 0.444 | |
| 3ey4 | 352 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.444 | |
| 3fhi | ANP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.444 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.444 | |
| 3oct | 1N1 | Tyrosine-protein kinase BTK | 2.7.10.2 | 0.444 | |
| 3p8j | FMN | Pentaerythritol tetranitrate reductase | / | 0.444 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.444 | |
| 4a2b | AGS | Cell division protein FtsA | / | 0.444 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.444 | |
| 4gg5 | 0J3 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.444 | |
| 4gyy | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.444 | |
| 4h95 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 4i1i | NAD | Malate dehydrogenase | / | 0.444 | |
| 4k39 | SAM | Anaerobic sulfatase-maturating enzyme | 1.8.98 | 0.444 | |
| 4lrr | CF9 | Thymidylate synthase | / | 0.444 | |
| 4rph | GDU | UDP-galactopyranose mutase | 5.4.99.9 | 0.444 | |
| 4tmc | FMN | Old yellow enzyme | / | 0.444 | |
| 4xfj | ANP | Argininosuccinate synthase | / | 0.444 | |
| 5ch7 | MD1 | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.444 | |
| 5ej9 | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.444 | |
| 1bcp | ATP | Pertussis toxin subunit 4 | / | 0.443 | |
| 1bcp | ATP | Pertussis toxin subunit 5 | / | 0.443 | |
| 1kc1 | NDP | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.443 | |
| 1vrw | NAI | Enoyl-ACP reductase | / | 0.443 | |
| 1xoq | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 1z2n | ADP | Inositol-tetrakisphosphate 1-kinase | 2.7.1.134 | 0.443 | |
| 2dt5 | NAD | Redox-sensing transcriptional repressor Rex | / | 0.443 | |
| 2eba | FAD | Putative glutaryl-CoA dehydrogenase | / | 0.443 | |
| 2g86 | UMP | Thymidylate synthase | / | 0.443 | |
| 2i1m | 5CN | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.443 | |
| 2idz | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 2nq8 | ZID | Enoyl-ACP reductase | / | 0.443 | |
| 2p9c | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.443 | |
| 2q3o | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.443 | |
| 2uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.443 | |
| 2xgs | 44P | Uncharacterized protein | / | 0.443 | |
| 2yg6 | FAD | Putrescine oxidase | / | 0.443 | |
| 3ae4 | N1M | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | 1.3.5.1 | 0.443 | |
| 3ae4 | N1M | Succinate dehydrogenase cytochrome b560 subunit, mitochondrial | / | 0.443 | |
| 3b4y | F42 | F420-dependent glucose-6-phosphate dehydrogenase | / | 0.443 | |
| 3beo | UD1 | UDP-N-acetylglucosamine 2-epimerase | / | 0.443 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.443 | |
| 3ha3 | SAH | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.443 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.443 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.443 | |
| 3srz | UPG | Toxin A | / | 0.443 | |
| 3tgy | ASC | Lactoperoxidase | 1.11.1.7 | 0.443 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.443 | |
| 3zxs | FAD | Deoxyribodipyrimidine photolyase-related protein | / | 0.443 | |
| 4b67 | NAP | L-ornithine N(5)-monooxygenase | / | 0.443 | |
| 4qzu | RTL | Retinol-binding protein 2 | / | 0.443 | |
| 5agy | GTB | Tau class glutathione S-transferase | / | 0.443 | |
| 5epe | SAH | Uncharacterized protein | / | 0.443 | |
| 1h36 | R88 | Squalene--hopene cyclase | 4.2.1.129 | 0.442 | |
| 1jmi | UMP | Thymidylate synthase | / | 0.442 | |
| 1nbm | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.442 | |
| 1nq2 | 4HY | Thyroid hormone receptor beta | / | 0.442 | |
| 1qbq | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.442 | |
| 1qbq | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.442 | |
| 1w2g | THM | Thymidylate kinase | 2.7.4.9 | 0.442 | |
| 1wsv | THH | Aminomethyltransferase, mitochondrial | / | 0.442 | |
| 2c2a | ADP | Sensor histidine kinase | / | 0.442 | |
| 2e98 | B29 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.442 | |
| 2fon | FAD | Acyl-coenzyme A oxidase | / | 0.442 | |
| 2nua | COA | Succinate--CoA ligase [ADP-forming] subunit alpha | 6.2.1.5 | 0.442 | |
| 2uze | C95 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 2v2q | NVG | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.442 | |
| 3c0i | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.442 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 3dwb | RDF | Endothelin-converting enzyme 1 | 3.4.24.71 | 0.442 | |
| 3ix3 | OHN | Transcriptional activator protein LasR | / | 0.442 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.442 | |
| 3qem | QEM | Glutamate receptor ionotropic, NMDA 2B | / | 0.442 | |
| 3qem | QEM | NMDA glutamate receptor subunit | / | 0.442 | |
| 3qly | 55V | Uncharacterized protein | / | 0.442 | |
| 3vrt | YS2 | Vitamin D3 receptor | / | 0.442 | |
| 3wow | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.442 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.442 | |
| 4h6z | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.442 | |
| 4lnb | ED5 | CaaX farnesyltransferase beta subunit Ram1 | / | 0.442 | |
| 4pzt | SOP | Histone acetyltransferase p300 | / | 0.442 | |
| 4xba | 5GP | Aprataxin-like protein | 3 | 0.442 | |
| 4xx0 | COA | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial | 6.2.1.4 | 0.442 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.442 | |
| 5fsx | ADP | Uncharacterized protein | / | 0.442 | |
| 5jtb | ZMA | Adenosine receptor A2a | / | 0.442 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.441 | |
| 1d6w | 00R | Prothrombin | 3.4.21.5 | 0.441 | |
| 1dq8 | COA | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.34 | 0.441 | |
| 1g16 | GDP | Ras-related protein SEC4 | / | 0.441 | |
| 1lhw | ESM | Sex hormone-binding globulin | / | 0.441 | |
| 1men | GAR | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.441 | |
| 1qmz | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 1rx7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1s0z | EB1 | Vitamin D3 receptor | / | 0.441 | |
| 1srf | MTB | Streptavidin | / | 0.441 | |
| 1tdu | CB3 | Thymidylate synthase | / | 0.441 | |
| 1ve3 | SAM | Uncharacterized protein | / | 0.441 | |
| 1xts | GTP | GTP-binding protein Rheb | / | 0.441 | |
| 2bf7 | HBI | Pteridine reductase 1 | 1.5.1.33 | 0.441 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.441 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.441 | |
| 2oxt | SAM | Genome polyprotein | / | 0.441 | |
| 2psw | COA | N-alpha-acetyltransferase 50 | / | 0.441 | |
| 2q4b | NAP | Uncharacterized protein At5g02240 | / | 0.441 | |
| 2rte | BTN | Streptavidin | / | 0.441 | |
| 2w71 | L23 | Biotin carboxylase | 6.3.4.14 | 0.441 | |
| 2x8g | FAD | Thioredoxin glutathione reductase | / | 0.441 | |
| 2xlr | NAP | Putative flavin-containing monooxygenase | / | 0.441 | |
| 2y6o | 1N1 | Ephrin type-A receptor 4 | 2.7.10.1 | 0.441 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.441 | |
| 3be9 | P04 | Casein kinase II subunit alpha | 2.7.11.1 | 0.441 | |
| 3bgx | TMP | Thymidylate synthase | / | 0.441 | |
| 3cob | ADP | Kinesin heavy chain-like protein | / | 0.441 | |
| 3dme | FAD | Putative conserved exported protein | / | 0.441 | |
| 3fqk | 79Z | Genome polyprotein | 2.7.7.48 | 0.441 | |
| 3frk | TQP | QdtB | / | 0.441 | |
| 3kb6 | NAD | D-lactate dehydrogenase | / | 0.441 | |
| 3pce | 3HP | Protocatechuate 3,4-dioxygenase alpha chain | 1.13.11.3 | 0.441 | |
| 3pce | 3HP | Protocatechuate 3,4-dioxygenase beta chain | 1.13.11.3 | 0.441 | |
| 4a06 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.441 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 4at3 | LTI | BDNF/NT-3 growth factors receptor | 2.7.10.1 | 0.441 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.441 | |
| 4dem | YS4 | Farnesyl pyrophosphate synthase | 2.5.1.10 | 0.441 | |
| 4e5k | NAD | Phosphonate dehydrogenase | 1.20.1.1 | 0.441 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.441 | |
| 4eqx | FAD | Coenzyme A disulfide reductase | / | 0.441 | |
| 4fdn | FAD | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.441 | |
| 4fox | D16 | Thymidylate synthase ThyA | / | 0.441 | |
| 4jr7 | GNP | Casein kinase II subunit alpha | 2.7.11.1 | 0.441 | |
| 4k88 | HFG | Bifunctional glutamate/proline--tRNA ligase | 6.1.1.15 | 0.441 | |
| 4qbj | NHM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.441 | |
| 4rqk | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.441 | |
| 4u7w | NDP | MxaA | / | 0.441 | |
| 4ydd | MD1 | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.441 | |
| 5kj1 | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.441 | |
| 1ddr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1eqh | FLP | Prostaglandin G/H synthase 1 | 1.14.99.1 | 0.440 | |
| 1iid | NHM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.440 | |
| 1lev | CLI | Fructose-1,6-bisphosphatase 1 | 3.1.3.11 | 0.440 | |
| 1luq | BTN | Streptavidin | / | 0.440 | |
| 1m4d | COA | Aminoglycoside 2'-N-acetyltransferase | 2.3.1 | 0.440 | |
| 2az3 | CDP | Nucleoside diphosphate kinase | / | 0.440 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 2b55 | D31 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 2bjf | DXC | Choloylglycine hydrolase | 3.5.1.24 | 0.440 | |
| 2brb | PFQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 2bxq | IMN | Serum albumin | / | 0.440 | |
| 2c96 | ATP | Psp operon transcriptional activator | / | 0.440 | |
| 2cjf | RP4 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.440 | |
| 2g8d | UMP | Thymidylate synthase | / | 0.440 | |
| 2op0 | 7PC | Enoyl-ACP reductase | / | 0.440 | |
| 2pdt | FAD | Vivid PAS protein VVD | / | 0.440 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 2vte | IK4 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.440 | |
| 2w6o | OA3 | Biotin carboxylase | 6.3.4.14 | 0.440 | |
| 2xyd | 3ES | Angiotensin-converting enzyme | 3.2.1 | 0.440 | |
| 2ylt | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.440 | |
| 2yut | NAP | Putative short-chain oxidoreductase | / | 0.440 | |
| 2z2w | 770 | Wee1-like protein kinase | 2.7.10.2 | 0.440 | |
| 3bej | MUF | Bile acid receptor | / | 0.440 | |
| 3da2 | 4MD | Carbonic anhydrase 13 | 4.2.1.1 | 0.440 | |
| 3ewr | APR | Replicase polyprotein 1a | 3.4.22 | 0.440 | |
| 3f63 | GTX | Glutathione transferase GST1-4 | / | 0.440 | |
| 3fgo | CZA | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.440 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3ruk | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.440 | |
| 3tc5 | 3T5 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | 5.2.1.8 | 0.440 | |
| 3ue4 | DB8 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.440 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.440 | |
| 3wv7 | ADP | Hmd co-occurring protein HcgE | / | 0.440 | |
| 3zqt | TES | Androgen receptor | / | 0.440 | |
| 4bwx | AGS | PAB-dependent poly(A)-specific ribonuclease subunit pan3 | / | 0.440 | |
| 4eil | UMP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.440 | |
| 4eiy | ZMA | Adenosine receptor A2a | / | 0.440 | |
| 4ffr | ATP | Uncharacterized protein | / | 0.440 | |
| 4ork | GDP | Bifunctional AAC/APH | 2.3.1 | 0.440 | |
| 4q0a | 4OA | Vitamin D3 receptor A | / | 0.440 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.440 | |
| 4uof | DAT | Nucleoside diphosphate kinase | / | 0.440 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.440 | |
| 5cb3 | APR | O-acetyl-ADP-ribose deacetylase | / | 0.440 | |
| 5dkk | FMN | Predicted protein | / | 0.440 |