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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2wgjVGHHepatocyte growth factor receptor2.7.10.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2wgjVGHHepatocyte growth factor receptor2.7.10.11.000
4gg70J8Hepatocyte growth factor receptor2.7.10.10.656
4gg50J3Hepatocyte growth factor receptor2.7.10.10.615
3zze6XPHepatocyte growth factor receptor2.7.10.10.607
4deg0JJHepatocyte growth factor receptor2.7.10.10.602
3a4pDFQHepatocyte growth factor receptor2.7.10.10.594
4ap7F47Hepatocyte growth factor receptor2.7.10.10.590
4aoi4K0Hepatocyte growth factor receptor2.7.10.10.588
3zc5W9ZHepatocyte growth factor receptor2.7.10.10.585
3zxzKRWHepatocyte growth factor receptor2.7.10.10.559
3zbx6XEHepatocyte growth factor receptor2.7.10.10.543
2wkmPFYHepatocyte growth factor receptor2.7.10.10.523
2xikJ60Serine/threonine-protein kinase 252.7.11.10.519
5e8wSTUTGF-beta receptor type-12.7.11.300.518
3iok1P6Tyrosine-protein kinase JAK2/0.515
4dymIYZActivin receptor type-12.7.11.300.515
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.510
4qmpDKISerine/threonine-protein kinase 242.7.11.10.509
4iwd1JCHepatocyte growth factor receptor2.7.10.10.507
3v5j0F2Tyrosine-protein kinase ITK/TSK2.7.10.20.506
4acg6LQGlycogen synthase kinase-3 beta2.7.11.260.506
2j4z626Aurora kinase A2.7.11.10.504
1h1s4SPCyclin-dependent kinase 22.7.11.220.503
1ir3ANPInsulin receptor2.7.10.10.503
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.502
1oi9N20Cyclin-dependent kinase 22.7.11.220.501
2b7aIZATyrosine-protein kinase JAK2/0.501
2uzlC94Cyclin-dependent kinase 22.7.11.220.500
2x1nX1NCyclin-dependent kinase 22.7.11.220.500
4jia1K3Tyrosine-protein kinase JAK2/0.500
3zep1NXTyrosine-protein kinase JAK32.7.10.20.498
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.498
1g5sI17Cyclin-dependent kinase 22.7.11.220.497
2wotZZGTGF-beta receptor type-12.7.11.300.497
3pjcPJCTyrosine-protein kinase JAK32.7.10.20.497
4gfo0X2Non-receptor tyrosine-protein kinase TYK22.7.10.20.497
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.497
1oguST8Cyclin-dependent kinase 22.7.11.220.494
5drdATPAurora kinase A2.7.11.10.494
1xjdSTUProtein kinase C theta type2.7.11.130.493
3iw4LW4Protein kinase C alpha type2.7.11.130.493
4erwSTUCyclin-dependent kinase 22.7.11.220.493
4riyADPEpidermal growth factor receptor2.7.10.10.492
4oacADPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.491
1qcfPP1Tyrosine-protein kinase HCK2.7.10.20.490
1u4dDBQActivated CDC42 kinase 1/0.490
2w1gL0GAurora kinase A2.7.11.10.490
2jkqVG8Focal adhesion kinase 12.7.10.20.489
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.489
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.489
1oirHDYCyclin-dependent kinase 22.7.11.220.488
3a60STURibosomal protein S6 kinase beta-12.7.11.10.488
3i81EBIInsulin-like growth factor 1 receptor2.7.10.10.488
4c61LMMTyrosine-protein kinase JAK2/0.488
4gmy0X5Tyrosine-protein kinase JAK2/0.488
1y91CT9Cyclin-dependent kinase 22.7.11.220.487
1e9hINRCyclin-dependent kinase 22.7.11.220.486
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.486
3e5aVX6Aurora kinase A2.7.11.10.486
3eyhIZATyrosine-protein kinase JAK1/0.486
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.486
4hvh19RTyrosine-protein kinase JAK32.7.10.20.485
2o65MYFSerine/threonine-protein kinase pim-12.7.11.10.484
3zmmF9JTyrosine-protein kinase JAK2/0.484
4wboANWRhodopsin kinase/0.484
3ddpRC8Cyclin-dependent kinase 22.7.11.220.483
3ibqATPPyridoxal kinase/0.483
3r02UNMSerine/threonine-protein kinase pim-12.7.11.10.483
4ewhT77Activated CDC42 kinase 1/0.483
4ivd15TTyrosine-protein kinase JAK1/0.483
1vjy460TGF-beta receptor type-12.7.11.300.482
2j2iLY4Serine/threonine-protein kinase pim-12.7.11.10.482
4l3j5FIRibosomal protein S6 kinase beta-12.7.11.10.482
4lopSB4Mitogen-activated protein kinase 14/0.482
2iw84SPCyclin-dependent kinase 22.7.11.220.481
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.481
4bcoT6QCyclin-dependent kinase 22.7.11.220.481
4qmtH1NSerine/threonine-protein kinase 242.7.11.10.481
1h1r6CPCyclin-dependent kinase 22.7.11.220.480
3lcdBDYMacrophage colony-stimulating factor 1 receptor2.7.10.10.480
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.480
3mtfA3FActivin receptor type-12.7.11.300.479
4qmlANPSerine/threonine-protein kinase 242.7.11.10.479
1aq1STUCyclin-dependent kinase 22.7.11.220.478
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.478
2in6839Wee1-like protein kinase2.7.10.20.478
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.477
2v7a627Tyrosine-protein kinase ABL12.7.10.20.477
3a7jADPSerine/threonine-protein kinase 242.7.11.10.477
4loqSB4Mitogen-activated protein kinase 14/0.477
1bwsNDPGDP-L-fucose synthase/0.476
1kl2FONSerine hydroxymethyltransferase/0.476
2cchATPCyclin-dependent kinase 22.7.11.220.476
2pmoHMDProtein kinase 7/0.476
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.476
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.476
1ke7LS3Cyclin-dependent kinase 22.7.11.220.475
2j0m4STFocal adhesion kinase 12.7.10.20.475
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.475
4gii0X6Non-receptor tyrosine-protein kinase TYK22.7.10.20.475
4hge15VTyrosine-protein kinase JAK2/0.475
1di8DTQCyclin-dependent kinase 22.7.11.220.474
1r2jFADFkbI/0.474
3v5l0G1Tyrosine-protein kinase ITK/TSK2.7.10.20.474
3vf80JETyrosine-protein kinase SYK2.7.10.20.474
2c5nCK8Cyclin-dependent kinase 22.7.11.220.473
2w1fL0FAurora kinase A2.7.11.10.473
3bgqVX2Serine/threonine-protein kinase pim-12.7.11.10.473
3gxlQIGTGF-beta receptor type-12.7.11.300.473
3we45FIRibosomal protein S6 kinase beta-12.7.11.10.473
4eomATPCyclin-dependent kinase 22.7.11.220.473
4eon1ROCyclin-dependent kinase 22.7.11.220.473
4lmuQUESerine/threonine-protein kinase pim-12.7.11.10.473
1u54ACPActivated CDC42 kinase 1/0.472
2i0v6C3Macrophage colony-stimulating factor 1 receptor2.7.10.10.472
2wxvWXVCyclin-dependent kinase 22.7.11.220.472
3k5uPFQAurora kinase A2.7.11.10.472
3l0lHC3Nuclear receptor ROR-gamma/0.472
4bgg844Activin receptor type-12.7.11.300.472
4feq0T8Tyrosine-protein kinase receptor TYRO32.7.10.10.472
4g7gVFVLanosterol 14-alpha-demethylase/0.472
4j95ACPFibroblast growth factor receptor 2/0.472
4krcAGSCyclin-dependent protein kinase PHO852.7.11.220.472
2vagV25Dual specificity protein kinase CLK12.7.12.10.471
3bhtMFRCyclin-dependent kinase 22.7.11.220.471
1bygSTUTyrosine-protein kinase CSK/0.470
1oiyN41Cyclin-dependent kinase 22.7.11.220.470
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.470
3a3yOBNSodium/potassium-transporting ATPase subunit alpha/0.470
3h0sB38Acetyl-CoA carboxylase/0.470
3mtlFEFCyclin-dependent kinase 162.7.11.220.470
3rk708ZCyclin-dependent kinase 22.7.11.220.470
4foc0UUALK tyrosine kinase receptor2.7.10.10.470
2i0y5CNMacrophage colony-stimulating factor 1 receptor2.7.10.10.469
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.469
3c1xCKKHepatocyte growth factor receptor2.7.10.10.469
4f650S9Fibroblast growth factor receptor 1/0.469
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.468
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.468
4eor4SPCyclin-dependent kinase 22.7.11.220.468
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.468
1bsvNDPGDP-L-fucose synthase/0.467
1yi3LY2Serine/threonine-protein kinase pim-12.7.11.10.467
2i0ePDSProtein kinase C beta type2.7.11.130.467
2ovhAS0Progesterone receptor/0.467
2xj1XJ1Serine/threonine-protein kinase pim-12.7.11.10.467
3bheBZNGag-Pol polyprotein3.4.23.160.467
3dcv55ESerine/threonine-protein kinase pim-12.7.11.10.467
3el7PD3Proto-oncogene tyrosine-protein kinase Src2.7.10.20.467
3rk507ZCyclin-dependent kinase 22.7.11.220.467
1yi4ADNSerine/threonine-protein kinase pim-12.7.11.10.466
2pwlACPFibroblast growth factor receptor 2/0.466
2wihP48Cyclin-dependent kinase 22.7.11.220.466
2wpa889Cyclin-dependent kinase 22.7.11.220.466
3qf9NM8Serine/threonine-protein kinase pim-12.7.11.10.466
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.466
3zc6VFCTyrosine-protein kinase JAK32.7.10.20.466
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.466
4e4m0NHTyrosine-protein kinase JAK2/0.466
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.466
3lpbNVBTyrosine-protein kinase JAK2/0.465
3uimANPBRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 12.7.10.10.465
3zh8C58Protein kinase C iota type2.7.11.130.465
3a4vNADNDP-sugar epimerase/0.464
3qu0X40Cyclin-dependent kinase 22.7.11.220.464
3s1dZIRCytokinin dehydrogenase 11.5.99.120.464
4bcpT3CCyclin-dependent kinase 22.7.11.220.464
4ei40Q2Tyrosine-protein kinase JAK1/0.464
4l3l5FIRibosomal protein S6 kinase beta-12.7.11.10.464
5bvw1N1Epithelial discoidin domain-containing receptor 12.7.10.10.464
1ad5ANPTyrosine-protein kinase HCK2.7.10.20.463
1csnATPCasein kinase I homolog 12.7.11.10.463
1uu3LY43-phosphoinositide-dependent protein kinase 12.7.11.10.463
4bbfO19Tyrosine-protein kinase JAK2/0.463
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.463
4dgo0JWCasein kinase II subunit alpha2.7.11.10.463
4eos1ROCyclin-dependent kinase 22.7.11.220.463
4eutBX7Serine/threonine-protein kinase TBK12.7.11.10.463
4k110J9Proto-oncogene tyrosine-protein kinase Src2.7.10.20.463
1rw8580TGF-beta receptor type-12.7.11.300.462
1vyw292Cyclin-dependent kinase 22.7.11.220.462
2bkzSBCCyclin-dependent kinase 22.7.11.220.462
2csnCKICasein kinase I homolog 12.7.11.10.462
2jedLG8Protein kinase C theta type2.7.11.130.462
2w05FRTCyclin-dependent kinase 22.7.11.220.462
2w1eL0EAurora kinase A2.7.11.10.462
2xa4AZ5Tyrosine-protein kinase JAK2/0.462
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.462
2z2w770Wee1-like protein kinase2.7.10.20.462
3nynSGVG protein-coupled receptor kinase 62.7.11.160.462
4i22IREEpidermal growth factor receptor2.7.10.10.462
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.462
4lm5Q17Serine/threonine-protein kinase pim-12.7.11.10.462
4o71CPBBromodomain-containing protein 4/0.462
4yuqKS1Calmodulin-like domain protein kinase/0.462
5dgzL20Serine/threonine-protein kinase pim-12.7.11.10.462
1pkdUCNCyclin-dependent kinase 22.7.11.220.461
1v9aSAHUncharacterized protein/0.461
2iw94SPCyclin-dependent kinase 22.7.11.220.461
2w9sTOPDihydrofolate reductase type 1 from Tn40031.5.1.30.461
3a7hATPSerine/threonine-protein kinase 242.7.11.10.461
3biz61EWee1-like protein kinase2.7.10.20.461
3pe6ZYHMonoglyceride lipase/0.461
3r1yX76Cyclin-dependent kinase 22.7.11.220.461
3t8oATPRhodopsin kinase/0.461
4l9i8PRRhodopsin kinase/0.461
4pkl1GHUncharacterized protein/0.461
4r20AERCytochrome P450 family 17 polypeptide 2/0.461
5dr6SKEAurora kinase A2.7.11.10.461
1u2gAPRNAD(P) transhydrogenase subunit alpha part 11.6.1.20.460
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.460
2izrBRKCasein kinase I isoform gamma-32.7.11.10.460
3bkbSTUTyrosine-protein kinase Fes/Fps2.7.10.20.460
3q9zTXQCasein kinase II subunit alpha2.7.11.10.460
3v8t477Tyrosine-protein kinase ITK/TSK2.7.10.20.460
4i0s1B5Tyrosine-protein kinase SYK2.7.10.20.460
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.459
1xddAAYIntegrin alpha-L/0.459
2c5yMTWCyclin-dependent kinase 22.7.11.220.459
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.459
3ggfGVDSerine/threonine-protein kinase 26/0.459
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.459
3rvg17PTyrosine-protein kinase JAK2/0.459
3sheI85MAP kinase-activated protein kinase 32.7.11.10.459
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.459
4c02TAKActivin receptor type-12.7.11.300.459
4ct2ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.459
4e93GUITyrosine-protein kinase Fes/Fps2.7.10.20.459
4fkr45KCyclin-dependent kinase 22.7.11.220.459
4grb0XGCasein kinase II subunit alpha2.7.11.10.459
4k6z1Q3Tyrosine-protein kinase JAK1/0.459
4kb81QOCasein kinase I isoform delta2.7.11.10.459
2i40BLZCyclin-dependent kinase 22.7.11.220.458
2ijmATPFocal adhesion kinase 12.7.10.20.458
2np8CC3Aurora kinase A2.7.11.10.458
2vgoAD5Aurora kinase B-A2.7.11.10.458
3jxwLXGSerine/threonine-protein kinase pim-12.7.11.10.458
3oqfS51Renin3.4.23.150.458
3qwkX62Cyclin-dependent kinase 22.7.11.220.458
3vbq0F5Serine/threonine-protein kinase pim-12.7.11.10.458
3w2cN15Aurora kinase A2.7.11.10.458
4acm7YGCyclin-dependent kinase 22.7.11.220.458
4dtk7LISerine/threonine-protein kinase pim-12.7.11.10.458
4eol1ROCyclin-dependent kinase 22.7.11.220.458
4fod0UVALK tyrosine kinase receptor2.7.10.10.458
4fx360KCyclin-dependent kinase 22.7.11.220.458
4gj20XHNon-receptor tyrosine-protein kinase TYK22.7.10.20.458
4qmzB49Serine/threonine-protein kinase 242.7.11.10.458
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.458
5aaaVGHALK tyrosine kinase receptor2.7.10.10.458
1oiuN76Cyclin-dependent kinase 22.7.11.220.457
1yhsSTUSerine/threonine-protein kinase pim-12.7.11.10.457
2f2cAP9Cyclin-dependent kinase 62.7.11.220.457
2j0j4STFocal adhesion kinase 12.7.10.20.457
2vmyFFOSerine hydroxymethyltransferase/0.457
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.457
2vu3LZECyclin-dependent kinase 22.7.11.220.457
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.457
3iqfE4MF420-dependent methylenetetrahydromethanopterin dehydrogenase1.5.98.10.457
3oqkS52Renin3.4.23.150.457
3sqq99ZCyclin-dependent kinase 22.7.11.220.457
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.457
4hni16WCasein kinase I isoform epsilon2.7.11.10.457
4ix5ANPUncharacterized protein/0.457
4ix6ADPUncharacterized protein/0.457
4lfiGNPCasein kinase II subunit alpha2.7.11.10.457
1fm4DXCMajor pollen allergen Bet v 1-L/0.456
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.456
2b52D42Cyclin-dependent kinase 22.7.11.220.456
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.456
2cppCAMCamphor 5-monooxygenase1.14.15.10.456
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.456
2uzeC95Cyclin-dependent kinase 22.7.11.220.456
3cr0809Wee1-like protein kinase2.7.10.20.456
3ezrEZRCyclin-dependent kinase 22.7.11.220.456
3s1h56ZCyclin-dependent kinase 22.7.11.220.456
3uixQ17Serine/threonine-protein kinase pim-12.7.11.10.456
4a7cE46Serine/threonine-protein kinase pim-12.7.11.10.456
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.456
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.456
4hgs15GCasein kinase I isoform gamma-32.7.11.10.456
4kioG5KTyrosine-protein kinase ITK/TSK2.7.10.20.456
4n6z2HWSerine/threonine-protein kinase pim-12.7.11.10.456
1unlRRCCyclin-dependent-like kinase 52.7.11.10.455
2io6330Wee1-like protein kinase2.7.10.20.455
2r64740Cyclin-dependent kinase 22.7.11.220.455
3hztJ60Calmodulin-like domain protein kinase isoform 3/0.455
3r7iX9ICyclin-dependent kinase 22.7.11.220.455
3uyt0CKCasein kinase I isoform delta2.7.11.10.455
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.455
4alhA9PBromodomain-containing protein 2/0.455
4aqc88ATyrosine-protein kinase JAK2/0.455
4bznUGXSerine/threonine-protein kinase pim-12.7.11.10.455
4fnyI3KALK tyrosine kinase receptor2.7.10.10.455
5dqrFAD7-hydroxymethyl chlorophyll a reductase, chloroplastic1.17.7.20.455
1h0w207Cyclin-dependent kinase 22.7.11.220.454
1h2bNAJNAD-dependent alcohol dehydrogenase/0.454
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.454
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.454
1ny3ADPMAP kinase-activated protein kinase 22.7.11.10.454
1rfvADPPyridoxal kinase2.7.1.350.454
1wvxBD4Death-associated protein kinase 12.7.11.10.454
1xwsBI1Serine/threonine-protein kinase pim-12.7.11.10.454
2bhhRYUCyclin-dependent kinase 22.7.11.220.454
2i1m5CNMacrophage colony-stimulating factor 1 receptor2.7.10.10.454
3a25SAMtRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase/0.454
3eljGS7Mitogen-activated protein kinase 82.7.11.240.454
3gobHXXDdmC/0.454
3hx4ANPCalmodulin-domain protein kinase 1/0.454
3qd33Q53-phosphoinositide-dependent protein kinase 12.7.11.10.454
3qzhX69Cyclin-dependent kinase 22.7.11.220.454
3vs2VSBTyrosine-protein kinase HCK2.7.10.20.454
4l425FIRibosomal protein S6 kinase beta-12.7.11.10.454
5av3KMPDeath-associated protein kinase 12.7.11.10.454
1eh4IC1Casein kinase I homolog 12.7.11.10.453
1wvgAPRCDP-glucose 4,6-dehydratase4.2.1.450.453
1yvj4STTyrosine-protein kinase JAK32.7.10.20.453
3ddqRRCCyclin-dependent kinase 22.7.11.220.453
3mdvCL6Cholesterol 24-hydroxylase/0.453
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.453
4bieIE6Mitogen-activated protein kinase kinase kinase 52.7.11.250.453
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.453
4dit0KDGlycogen synthase kinase-3 beta2.7.11.260.453
4qnaX11Serine/threonine-protein kinase 242.7.11.10.453
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.453
1rf9DBRCamphor 5-monooxygenase1.14.15.10.452
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.452
2i4pDRHPeroxisome proliferator-activated receptor gamma/0.452
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.452
2v59LZKBiotin carboxylase6.3.4.140.452
2xru400Aurora kinase A2.7.11.10.452
3cy3JN5Serine/threonine-protein kinase pim-12.7.11.10.452
3fz1B98Cyclin-dependent kinase 22.7.11.220.452
3i60E86Mitogen-activated protein kinase 12.7.11.240.452
3jpv1DRSerine/threonine-protein kinase pim-12.7.11.10.452
3l8p0CEAngiopoietin-1 receptor2.7.10.10.452
3r9dX6BCyclin-dependent kinase 22.7.11.220.452
3rni21ZCyclin-dependent kinase 22.7.11.220.452
4acdGR9Glycogen synthase kinase-3 beta2.7.11.260.452
4b7sQLECytochrome P450 monooxygenase PikC/0.452
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.452
4ipw1G7Mycocyclosin synthase1.14.21.90.452
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.452
4k8aK8AFocal adhesion kinase 12.7.10.20.452
5jscFADPutative acyl-CoA dehydrogenase/0.452
1dnaCB3Thymidylate synthase/0.451
1e7qNAPGDP-L-fucose synthase/0.451
1k7fIAVTryptophan synthase alpha chain/0.451
1nzdUPGDNA beta-glucosyltransferase/0.451
1q4u4CA4-hydroxybenzoyl-CoA thioesterase3.1.2.230.451
1r78FMDCyclin-dependent kinase 22.7.11.220.451
2j9mPY8Cyclin-dependent kinase 22.7.11.220.451
2owkSAHDiphthine synthase/0.451
2p5fSAHDiphthine synthase/0.451
2uzbC75Cyclin-dependent kinase 22.7.11.220.451
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.451
2wouZZFTGF-beta receptor type-12.7.11.300.451
3il1B5DGlutamate receptor 2/0.451
3rak03ZCyclin-dependent kinase 22.7.11.220.451
3vw6IM6Mitogen-activated protein kinase kinase kinase 52.7.11.250.451
4ezk0SDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
4fks46KCyclin-dependent kinase 22.7.11.220.451
4ivc1J6Tyrosine-protein kinase JAK1/0.451
4o0sADNAurora kinase A2.7.11.10.451
5aabVGHALK tyrosine kinase receptor2.7.10.10.451
1ol5ADPAurora kinase A2.7.11.10.450
1om1IQACasein kinase II subunit alpha2.7.11.10.450
1u3dFADCryptochrome-1/0.450
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.450
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.450
2uxoTACHTH-type transcriptional regulator TtgR/0.450
2xj2985Serine/threonine-protein kinase pim-12.7.11.10.450
2xlsFADPutative flavin-containing monooxygenase/0.450
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.450
3bu5ATPInsulin receptor2.7.10.10.450
3f03FMNPentaerythritol tetranitrate reductase/0.450
3hmm855TGF-beta receptor type-12.7.11.300.450
3l1sZ92Glycogen synthase kinase-3 beta2.7.11.260.450
4qo9627Serine/threonine-protein kinase 242.7.11.10.450
4wkqIREEpidermal growth factor receptor2.7.10.10.450
4z63ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.450
1o6yACPSerine/threonine-protein kinase PknB2.7.11.10.449
1p44GEQEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.449
1rfuADPPyridoxal kinase2.7.1.350.449
2obyNAPQuinone oxidoreductase PIG310.449
2pvhP19Casein kinase II subunit alpha2.7.11.10.449
2y46MIVMycinamicin IV hydroxylase/epoxidase/0.449
3amaSKEcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.449
3ambVX6cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.449
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.449
3my5RFZCyclin-dependent kinase 22.7.11.220.449
3nwq2NCGag-Pol polyprotein3.4.23.160.449
3plsANPMacrophage-stimulating protein receptor2.7.10.10.449
3r9oZ71Cyclin-dependent kinase 22.7.11.220.449
3s2pPMUCyclin-dependent kinase 22.7.11.220.449
3t2zFADSulfide-quinone reductase/0.449
3vryB43Tyrosine-protein kinase HCK2.7.10.20.449
4at3LTIBDNF/NT-3 growth factors receptor2.7.10.10.449
4ckiADNProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.449
4ek816KCyclin-dependent kinase 22.7.11.220.449
4fko20KCyclin-dependent kinase 22.7.11.220.449
4gu610NFocal adhesion kinase 12.7.10.20.449
4o0wADNAurora kinase A2.7.11.10.449
4oa9ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.449
1m2qMNXCasein kinase II subunit alpha2.7.11.10.448
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.448
2chlDKICasein kinase I isoform gamma-32.7.11.10.448
2puiADPMethylthioribose kinase2.7.1.1000.448
2wmxZY6Serine/threonine-protein kinase Chk12.7.11.10.448
2wyvNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.448
3a62STURibosomal protein S6 kinase beta-12.7.11.10.448
3cqeP91Wee1-like protein kinase2.7.10.20.448
3f69XDRSerine/threonine-protein kinase PknB2.7.11.10.448
3kgaLX9MAP kinase-activated protein kinase 22.7.11.10.448
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.448
4c2yMYAGlycylpeptide N-tetradecanoyltransferase 1/0.448
4f630S7Fibroblast growth factor receptor 1/0.448
4hvi19STyrosine-protein kinase JAK32.7.10.20.448
4mwhATPCasein kinase II subunit alpha2.7.11.10.448
4ocpADPN-acetylhexosamine 1-kinase2.7.1.1620.448
4q5jANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.448
4r8qADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.448
5dr2ATPAurora kinase A2.7.11.10.448
5hs1VORLanosterol 14-alpha demethylase/0.448
1fvv107Cyclin-dependent kinase 22.7.11.220.447
1k6pXN3Gag-Pol polyprotein3.4.23.160.447
1pkgADPMast/stem cell growth factor receptor Kit2.7.10.10.447
1ppjANYCytochrome b/0.447
1qiqACCIsopenicillin N synthase1.21.3.10.447
1tqf32PBeta-secretase 13.4.23.460.447
2c3kABOSerine/threonine-protein kinase Chk12.7.11.10.447
2ckeIQUDeath-associated protein kinase 2/0.447
2jkkBI9Focal adhesion kinase 12.7.10.20.447
2owuSAHDiphthine synthase/0.447
2pulACPMethylthioribose kinase2.7.1.1000.447
2qblCAMCamphor 5-monooxygenase1.14.15.10.447
2y98MIVMycinamicin IV hydroxylase/epoxidase/0.447
3qqkX02Cyclin-dependent kinase 22.7.11.220.447
3wi6YRZMAP kinase-activated protein kinase 22.7.11.10.447
4dgnLU2Casein kinase II subunit alpha2.7.11.10.447
4fic0ULProto-oncogene tyrosine-protein kinase Src2.7.10.20.447
4hvb19PPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
4jqeANPCasein kinase II subunit alpha2.7.11.10.447
4ryvZEAProtein LlR18A/0.447
5av2KMPDeath-associated protein kinase 12.7.11.10.447
5cwa0GAAnthranilate synthase component 14.1.3.270.447
1e7vLY2Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
1gy3ATPCyclin-dependent kinase 22.7.11.220.446
1h1q2A6Cyclin-dependent kinase 22.7.11.220.446
1jpaANPEphrin type-B receptor 22.7.10.10.446
1ykr628Cyclin-dependent kinase 22.7.11.220.446
2b9iADPMitogen-activated protein kinase FUS32.7.11.240.446
2c3qGTXGlutathione S-transferase theta-12.5.1.180.446
2etm7PYFocal adhesion kinase 12.7.10.20.446
2pe039Z3-phosphoinositide-dependent protein kinase 12.7.11.10.446
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.446
2xnbY8LCyclin-dependent kinase 22.7.11.220.446
2zjwREFCasein kinase II subunit alpha2.7.11.10.446
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.446
3nrrD16Bifunctional dihydrofolate reductase-thymidylate synthase/0.446
3p99LNPLanosterol 14-alpha-demethylase/0.446
3pxkPXKFocal adhesion kinase 12.7.10.20.446
3qaiXNNKetohexokinase/0.446
3r7eX88Cyclin-dependent kinase 22.7.11.220.446
3tnwF18Cyclin-dependent kinase 22.7.11.220.446
3vs5VSGTyrosine-protein kinase HCK2.7.10.20.446
4achKDIGlycogen synthase kinase-3 beta2.7.11.260.446
4af3VX6Aurora kinase B2.7.11.10.446
4e1z0MXNon-receptor tyrosine-protein kinase TYK22.7.10.20.446
4ez8DHFThymidylate synthase2.1.1.450.446
4ii5ADPCyclin-dependent kinase 22.7.11.220.446
4k33ACPFibroblast growth factor receptor 32.7.10.10.446
1siqFADGlutaryl-CoA dehydrogenase, mitochondrial1.3.8.60.445
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.445
2hckQUETyrosine-protein kinase HCK2.7.10.20.445
2jkoBIJFocal adhesion kinase 12.7.10.20.445
2pwcG3GGag-Pol polyprotein3.4.23.160.445
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.445
2xngA0HAurora kinase A2.7.11.10.445
3bc3OPTCathepsin L13.4.22.150.445
3bqr4RBDeath-associated protein kinase 3/0.445
3kb1ADPIron-sulfur cluster carrier protein/0.445
3oom507Activin receptor type-12.7.11.300.445
3r374CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.445
3u9eCOALmo1369 protein/0.445
3w32W32Epidermal growth factor receptor2.7.10.10.445
4bcmT7ZCyclin-dependent kinase 22.7.11.220.445
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.445
4fhj0TZPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
4fkw62KCyclin-dependent kinase 22.7.11.220.445
4fob0USALK tyrosine kinase receptor2.7.10.10.445
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.445
4gj30XPNon-receptor tyrosine-protein kinase TYK22.7.10.20.445
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.445
4kzoNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.445
4ockANPN-acetylhexosamine 1-kinase2.7.1.1620.445
4qmySTUSerine/threonine-protein kinase 242.7.11.10.445
5ejaTD62-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.445
2c6lDT4Cyclin-dependent kinase 22.7.11.220.444
2e8qSAHDiphthine synthase/0.444
2om9AJAPeroxisome proliferator-activated receptor gamma/0.444
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.444
2qhn582Serine/threonine-protein kinase Chk12.7.11.10.444
2vn0TDZCytochrome P450 2C8/0.444
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.444
3beaIXHMacrophage colony-stimulating factor 1 receptor2.7.10.10.444
3c1tMYCDihydroflavonol 4-reductase1.1.1.2190.444
3i59N6RCRP-like cAMP-activated global transcriptional regulator/0.444
3r6xX84Cyclin-dependent kinase 22.7.11.220.444
3r71X86Cyclin-dependent kinase 22.7.11.220.444
3rkb12ZCyclin-dependent kinase 22.7.11.220.444
3t2kFADSulfide-quinone reductase/0.444
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
4cztCPSCBL-interacting serine/threonine-protein kinase 232.7.11.10.444
4deaNHIAurora kinase A2.7.11.10.444
4im2BX7Serine/threonine-protein kinase TBK12.7.11.10.444
4k0y1OASerine/threonine-protein kinase pim-12.7.11.10.444
4mcc21XtRNA (guanine-N(1)-)-methyltransferase2.1.1.2280.444
4xgxADPFAD:protein FMN transferase/0.444
5auwQUEDeath-associated protein kinase 12.7.11.10.444
5e8xSTUTGF-beta receptor type-12.7.11.300.444
1bwlFMNNADPH dehydrogenase 11.6.99.10.443
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.443
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
1h63FMNPentaerythritol tetranitrate reductase/0.443
1xl2189Gag-Pol polyprotein3.4.23.160.443
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.443
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.443
2e16SAHDiphthine synthase/0.443
2g20L1ARenin3.4.23.150.443
2v4lABJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.443
2zbaZBATrichothecene 3-O-acetyltransferase/0.443
3c4eC4ESerine/threonine-protein kinase pim-12.7.11.10.443
3hdmMMGSerine/threonine-protein kinase Sgk12.7.11.10.443
3lq5SLQCyclin-dependent kinase 92.7.11.220.443
3lxpIZANon-receptor tyrosine-protein kinase TYK22.7.10.20.443
3qtzX42Cyclin-dependent kinase 22.7.11.220.443
3r8lZ30Cyclin-dependent kinase 22.7.11.220.443
3rpr25ZCyclin-dependent kinase 22.7.11.220.443
4bqpVMYEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.443
4bzo676Serine/threonine-protein kinase pim-12.7.11.10.443
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.443
4ia1BIVVitamin D3 receptor A/0.443
4ibmIR1Insulin receptor2.7.10.10.443
4ijp1EHSerine/threonine-protein kinase PRP4 homolog2.7.11.10.443
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.443
4looSB4Mitogen-activated protein kinase 14/0.443
5bukFADFADH2-dependent halogenase/0.443
5c8wPCGcGMP-dependent protein kinase 22.7.11.120.443
5dt3ATPAurora kinase A2.7.11.10.443
1dz6CAMCamphor 5-monooxygenase1.14.15.10.442
1j7kATPHolliday junction ATP-dependent DNA helicase RuvB/0.442
1mq4ADPAurora kinase A2.7.11.10.442
1q41IXMGlycogen synthase kinase-3 beta2.7.11.260.442
1t87CAMCamphor 5-monooxygenase1.14.15.10.442
1t9gFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.442
1xr1ANPSerine/threonine-protein kinase pim-12.7.11.10.442
2bkkADPAminoglycoside 3'-phosphotransferase2.7.1.950.442
2gdo12CSerine/threonine-protein kinase Chk12.7.11.10.442
2hr8SAHDiphthine synthase/0.442
2izsBRQCasein kinase I isoform gamma-32.7.11.10.442
2jcvNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.442
2jfgUMAUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.442
2ok7FADFerredoxin--NADP reductase, apicoplast/0.442
2p33J07Mitogen-activated protein kinase 102.7.11.240.442
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.442
2yn8STUEphrin type-B receptor 42.7.10.10.442
3clrFADElectron transfer flavoprotein subunit alpha/0.442
3dogNNNCyclin-dependent kinase 22.7.11.220.442
3ezvEZVCyclin-dependent kinase 22.7.11.220.442
3nj0PYVAbscisic acid receptor PYL2/0.442
3qaqQAQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
3qcs3Q13-phosphoinositide-dependent protein kinase 12.7.11.10.442
3uzp0CKCasein kinase I isoform delta2.7.11.10.442
3vrzVRZTyrosine-protein kinase HCK2.7.10.20.442
4b1fKRHGlutamate racemase/0.442
4b99R4LMitogen-activated protein kinase 72.7.11.240.442
4c67L5SBromodomain-containing protein 4/0.442
4cfnJYMCyclin-dependent kinase 22.7.11.220.442
4enyJ19Serine/threonine-protein kinase pim-12.7.11.10.442
4f9c0SXCell division cycle 7-related protein kinase2.7.11.10.442
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.442
4g1z0VPVitamin D3 receptor A/0.442
4gvjADPNon-receptor tyrosine-protein kinase TYK22.7.10.20.442
4j1rI5RGlycogen synthase kinase-3 beta2.7.11.260.442
4jr7GNPCasein kinase II subunit alpha2.7.11.10.442
4mbl26LSerine/threonine-protein kinase pim-12.7.11.10.442
4neuQ1AReceptor-interacting serine/threonine-protein kinase 12.7.11.10.442
4nk92K5Fibroblast growth factor receptor 1/0.442
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.442
1axwMTXThymidylate synthase/0.441
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.441
1zthADPRIO-type serine/threonine-protein kinase Rio12.7.11.10.441
2c6iDT1Cyclin-dependent kinase 22.7.11.220.441
2en5SAHDiphthine synthase/0.441
2h96893Mitogen-activated protein kinase 82.7.11.240.441
2hutSAHDiphthine synthase/0.441
2olcADPMethylthioribose kinase2.7.1.1000.441
2vv9IM9Cyclin-dependent kinase 22.7.11.220.441
2xmyCDKCyclin-dependent kinase 22.7.11.220.441
3c50ADPRhodopsin kinase/0.441
3cxw7CPSerine/threonine-protein kinase pim-12.7.11.10.441
3dds26BGlycogen phosphorylase, liver form2.4.1.10.441
3dxjNE6DNA-directed RNA polymerase subunit beta/0.441
3dxjNE6DNA-directed RNA polymerase subunit beta'/0.441
3emg685Tyrosine-protein kinase SYK2.7.10.20.441
3keuATPPyridoxal kinase2.7.1.350.441
3nbvANPKetohexokinase/0.441
3nr4PYVAbscisic acid receptor PYL2/0.441
3pxyJWSCyclin-dependent kinase 22.7.11.220.441
3qlg1N1Proto-oncogene tyrosine-protein kinase Src2.7.10.20.441
3qruX19Cyclin-dependent kinase 22.7.11.220.441
3qtuX44Cyclin-dependent kinase 22.7.11.220.441
3tm0ANPAminoglycoside 3'-phosphotransferase2.7.1.950.441
3zuyTCHTransporter/0.441
4a83DXCMajor pollen allergen Bet v 1-A/0.441
4a9hTVPBromodomain-containing protein 2/0.441
4awiAQ2Mitogen-activated protein kinase 82.7.11.240.441
4b722FBBeta-secretase 13.4.23.460.441
4c57FEFCyclin-G-associated kinase2.7.11.10.441
4c62XWWTyrosine-protein kinase JAK2/0.441
4dtaADNAPH(2'')-Id/0.441
4eoi1ROCyclin-dependent kinase 22.7.11.220.441
4eok4SPCyclin-dependent kinase 22.7.11.220.441
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.441
4l9kEHFSerum albumin/0.441
4nmbFADBifunctional protein PutA/0.441
4uyf73BBromodomain-containing protein 2/0.441
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.441
5d12G97Proto-oncogene tyrosine-protein kinase Src2.7.10.20.441
5eypLOCTubulin beta chain/0.441
1a72PADAlcohol dehydrogenase E chain1.1.1.10.440
1dnpFADDeoxyribodipyrimidine photo-lyase4.1.99.30.440
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.440
1owmFADDeoxyribodipyrimidine photo-lyase4.1.99.30.440
1pmn984Mitogen-activated protein kinase 102.7.11.240.440
1pxoCK7Cyclin-dependent kinase 22.7.11.220.440
1qnfFADDeoxyribodipyrimidine photo-lyase4.1.99.30.440
2bikBI1Serine/threonine-protein kinase pim-12.7.11.10.440
2eglSAHDiphthine synthase/0.440
2huvSAHDiphthine synthase/0.440
2nq8ZIDEnoyl-ACP reductase/0.440
2x2kX2KProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.440
2yac937Serine/threonine-protein kinase PLK12.7.11.210.440
2yexYEXSerine/threonine-protein kinase Chk12.7.11.10.440
3ddw055Glycogen phosphorylase, liver form2.4.1.10.440
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.440
3kpkFADSulfide-quinone reductase/0.440
3own3OWRenin3.4.23.150.440
3r8zZ63Cyclin-dependent kinase 22.7.11.220.440
3rjc06ZCyclin-dependent kinase 22.7.11.220.440
4fv5EK9Mitogen-activated protein kinase 12.7.11.240.440
4gk2L66Ephrin type-A receptor 32.7.10.10.440
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
4yryFADGlutamate synthase, beta subunit/0.440
5hes032Mitogen-activated protein kinase kinase kinase 202.7.11.250.440