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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2wetFADTryptophan 5-halogenase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2wetFADTryptophan 5-halogenase/1.000
2wesFADTryptophan 5-halogenase/0.639
5hy5FADTryptophan 6-halogenase/0.577
2ardFDAFlavin-dependent tryptophan halogenase PrnA1.14.19.90.572
4z44FADFlavin-dependent tryptophan halogenase PrnA1.14.19.90.557
2ar8FADFlavin-dependent tryptophan halogenase PrnA1.14.19.90.526
2apgFADFlavin-dependent tryptophan halogenase PrnA1.14.19.90.521
2oa1FADFlavin-dependent tryptophan halogenase RebH1.14.19.90.461