Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2wd7VGDPteridine reductase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2wd7VGDPteridine reductase/1.000
3jqbDX6Pteridine reductase, putative/0.678
2vz0D64Pteridine reductase/0.658
2yhuWHFPteridine reductase/0.632
3bmqAX5Pteridine reductase/0.631
3bmcFOLPteridine reductase/0.623
3jq9AX1Pteridine reductase, putative/0.623
2x9gLYAPteridine reductase/0.620
3jqgAX6Pteridine reductase, putative/0.618
2x9vTMQPteridine reductase/0.604
1p33MTXPteridine reductase 11.5.1.330.602
3jq7DX2Pteridine reductase, putative/0.599
3mcvMCVPteridine reductase/0.579
2x9nAX3Pteridine reductase/0.573
3jq6DX1Pteridine reductase, putative/0.572
3jq8DX3Pteridine reductase, putative/0.571
1e7wMTXPteridine reductase 11.5.1.330.548
3bmnAX3Pteridine reductase/0.543
1mxfMTXPutative pteridine reductase 2/0.517
2qhxFE1Pteridine reductase 11.5.1.330.497
2bfmTOPPteridine reductase 11.5.1.330.494
2bfpH4BPteridine reductase 11.5.1.330.472
1kyxCRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.470
4wx2F6FTryptophan synthase alpha chain/0.469
4wx2F6FTryptophan synthase beta chain4.2.1.200.469
3h4vDVPPteridine reductase 11.5.1.330.467
1e92HBIPteridine reductase 11.5.1.330.466
1ejbINJ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.456
3jqcJU2Pteridine reductase, putative/0.456
2wd8VGFPteridine reductase/0.455
4f0fACPProbable serine/threonine-protein kinase roco42.7.11.10.454
4fex0TOAminoglycoside 3'-phosphotransferase AphA1-IAB/0.453
3gn2AX8Pteridine reductase/0.450
4f1oACPProbable serine/threonine-protein kinase roco42.7.11.10.446
3biz61EWee1-like protein kinase2.7.10.20.445
2z2w770Wee1-like protein kinase2.7.10.20.444
1nquRDL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.442
2b365PPEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
3cqeP91Wee1-like protein kinase2.7.10.20.440