sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2w3w | VG9 | Dihydrofolate reductase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2w3w | VG9 | Dihydrofolate reductase | / | 1.000 | |
| 1vj3 | TAB | Dihydrofolate reductase | 1.5.1.3 | 0.577 | |
| 1cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.571 | |
| 3eek | 53S | Uncharacterized protein | / | 0.552 | |
| 4dp3 | MMV | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.552 | |
| 1rx3 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.550 | |
| 4h98 | 14Q | Uncharacterized protein | / | 0.547 | |
| 4fgg | 0U5 | Dihydrofolate reductase | 1.5.1.3 | 0.544 | |
| 3fre | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.542 | |
| 3i8a | N22 | Dihydrofolate reductase | 1.5.1.3 | 0.542 | |
| 3qfx | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.537 | |
| 2fzh | DH1 | Dihydrofolate reductase | 1.5.1.3 | 0.528 | |
| 1df7 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.527 | |
| 2w3v | TOP | Dihydrofolate reductase | / | 0.527 | |
| 1klk | PMD | Dihydrofolate reductase | 1.5.1.3 | 0.526 | |
| 2fzi | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.525 | |
| 3eel | 53T | Uncharacterized protein | / | 0.523 | |
| 3srq | Q19 | Dihydrofolate reductase | 1.5.1.3 | 0.523 | |
| 4ixf | IXF | Dihydrofolate reductase | 1.5.1.3 | 0.522 | |
| 1dg5 | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.519 | |
| 3qlz | QLZ | Uncharacterized protein | / | 0.519 | |
| 4ixg | IXG | Dihydrofolate reductase | 1.5.1.3 | 0.519 | |
| 3sa2 | 7DR | Dihydrofolate reductase | / | 0.517 | |
| 2bl9 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.516 | |
| 1jol | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.515 | |
| 4x5g | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.515 | |
| 3sai | 9DR | Dihydrofolate reductase | / | 0.514 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.513 | |
| 3rg9 | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.513 | |
| 1j3i | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.512 | |
| 3inv | C50 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.511 | |
| 4xe6 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.509 | |
| 4p66 | MTX | Dihydrofolate reductase | / | 0.508 | |
| 3kjs | DQ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.507 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.506 | |
| 1dg7 | WRB | Dihydrofolate reductase | 1.5.1.3 | 0.504 | |
| 3dga | RJ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.502 | |
| 3cse | N22 | Uncharacterized protein | / | 0.501 | |
| 4m2x | TMQ | Dihydrofolate reductase | 1.5.1.3 | 0.499 | |
| 3sa1 | 6DR | Dihydrofolate reductase | / | 0.498 | |
| 2cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.497 | |
| 3ia4 | MTX | Dihydrofolate reductase | / | 0.496 | |
| 4h95 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.496 | |
| 1ia1 | TQ3 | Dihydrofolate reductase | 1.5.1.3 | 0.494 | |
| 3qlx | QLR | Uncharacterized protein | / | 0.494 | |
| 3qlw | N22 | Dihydrofolate reductase | 1.5.1.3 | 0.493 | |
| 4dph | P65 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.493 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.492 | |
| 3eej | 53R | Uncharacterized protein | / | 0.492 | |
| 3td8 | D2R | Dihydrofolate reductase | 1.5.1.3 | 0.492 | |
| 3dau | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.491 | |
| 3qgt | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.490 | |
| 3qg2 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.489 | |
| 1j3j | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.488 | |
| 3nxv | D2F | Dihydrofolate reductase | 1.5.1.3 | 0.487 | |
| 3tk3 | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.487 | |
| 4x5f | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.487 | |
| 1rf7 | DHF | Dihydrofolate reductase | 1.5.1.3 | 0.486 | |
| 3ml8 | ML8 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.486 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.486 | |
| 1aoe | GW3 | Dihydrofolate reductase | 1.5.1.3 | 0.485 | |
| 3jw5 | TOP | Dihydrofolate reductase | / | 0.485 | |
| 4dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.485 | |
| 5ccc | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.485 | |
| 1hfp | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.484 | |
| 1m78 | CLZ | Dihydrofolate reductase | 1.5.1.3 | 0.484 | |
| 4g8z | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.484 | |
| 4gg7 | 0J8 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.484 | |
| 4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.482 | |
| 4h96 | 14Q | Dihydrofolate reductase | 1.5.1.3 | 0.482 | |
| 4nkv | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.482 | |
| 1m7a | MQU | Dihydrofolate reductase | 1.5.1.3 | 0.481 | |
| 2hw2 | RFP | Rifampin ADP-ribosyl transferase | / | 0.481 | |
| 1lud | TRR | Dihydrofolate reductase | 1.5.1.3 | 0.480 | |
| 1rx8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.480 | |
| 3eem | 53V | Uncharacterized protein | / | 0.480 | |
| 3kjm | 245 | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.480 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.480 | |
| 1rx2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.479 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.479 | |
| 4v12 | POG | MaoC like domain protein | / | 0.479 | |
| 4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.478 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.478 | |
| 4kjj | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.478 | |
| 3t3r | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.477 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.477 | |
| 1boz | PRD | Dihydrofolate reductase | 1.5.1.3 | 0.475 | |
| 1dyr | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.475 | |
| 2gtn | LIE | Mitogen-activated protein kinase 14 | / | 0.475 | |
| 3u8l | 09Q | Acetylcholine-binding protein | / | 0.475 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
| 2drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
| 3ibd | CPZ | Cytochrome P450 2B6 | 1.14.13 | 0.474 | |
| 3qlr | QLR | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
| 1dz4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.473 | |
| 1fml | RTL | Retinol dehydratase | / | 0.473 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.473 | |
| 3nxy | D2H | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
| 1dyj | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.472 | |
| 2w6o | OA3 | Biotin carboxylase | 6.3.4.14 | 0.472 | |
| 3jzi | JZL | Biotin carboxylase | 6.3.4.14 | 0.472 | |
| 1db4 | 8IN | Phospholipase A2, membrane associated | / | 0.471 | |
| 1vce | SAH | Diphthine synthase | / | 0.471 | |
| 3a4p | DFQ | Hepatocyte growth factor receptor | 2.7.10.1 | 0.471 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.471 | |
| 3nxr | D2D | Dihydrofolate reductase | 1.5.1.3 | 0.471 | |
| 3qly | 55V | Uncharacterized protein | / | 0.471 | |
| 4c3y | ANB | 3-ketosteroid dehydrogenase | / | 0.471 | |
| 4cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.471 | |
| 5a3c | NAD | SIR2 family protein | / | 0.471 | |
| 1cjt | FOK | Adenylate cyclase type 2 | / | 0.470 | |
| 1cjt | FOK | Adenylate cyclase type 5 | / | 0.470 | |
| 1qzf | FOL | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.470 | |
| 2j9g | ANP | Biotin carboxylase | 6.3.4.14 | 0.470 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.470 | |
| 3tq9 | MTX | Dihydrofolate reductase | / | 0.470 | |
| 2bra | FAD | [F-actin]-methionine sulfoxide oxidase MICAL1 | 1.14.13 | 0.469 | |
| 2om9 | AJA | Peroxisome proliferator-activated receptor gamma | / | 0.469 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.469 | |
| 4ib4 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.469 | |
| 4nx6 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 1daj | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.468 | |
| 3ql3 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 3um6 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.468 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.467 | |
| 1qxl | FR8 | Adenosine deaminase | 3.5.4.4 | 0.467 | |
| 2o65 | MYF | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.467 | |
| 3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.467 | |
| 3fy8 | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 3lu8 | IQX | Serum albumin | / | 0.467 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.467 | |
| 4nx7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 2qbo | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.466 | |
| 3t3q | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.466 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.465 | |
| 1kqu | BR4 | Phospholipase A2, membrane associated | / | 0.465 | |
| 1w1r | ZEA | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.465 | |
| 3iro | 2CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.465 | |
| 3w5r | LOA | Vitamin D3 receptor | / | 0.465 | |
| 4b72 | 2FB | Beta-secretase 1 | 3.4.23.46 | 0.465 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.464 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.464 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.464 | |
| 3cd2 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 3fwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.464 | |
| 3jsu | KA5 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.464 | |
| 1dyi | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.463 | |
| 2a1n | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.463 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.463 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.463 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.463 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.463 | |
| 3mtl | FEF | Cyclin-dependent kinase 16 | 2.7.11.22 | 0.463 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.463 | |
| 4yer | ADP | Antibiotic ABC transporter, ATP-binding protein, putative | / | 0.463 | |
| 1nq2 | 4HY | Thyroid hormone receptor beta | / | 0.462 | |
| 1ra2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 1re7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 1suo | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.462 | |
| 2ejz | SAH | Diphthine synthase | / | 0.462 | |
| 2v58 | LZJ | Biotin carboxylase | 6.3.4.14 | 0.462 | |
| 2xpu | TDC | Tetracycline repressor protein class D | / | 0.462 | |
| 2y98 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.462 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.462 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.462 | |
| 4ejh | 0QA | Cytochrome P450 2A13 | 1.14.14.1 | 0.462 | |
| 4j6b | PLO | Cytochrome P450 monooxygenase | / | 0.462 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.461 | |
| 2q5g | 1FA | Peroxisome proliferator-activated receptor delta | / | 0.461 | |
| 2rkv | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.461 | |
| 2vd0 | D27 | Hematopoietic prostaglandin D synthase | / | 0.461 | |
| 2x7j | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.461 | |
| 3w0g | W07 | Vitamin D3 receptor | / | 0.461 | |
| 4ge7 | 0K5 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.461 | |
| 2cdu | FAD | NADH oxidase | / | 0.460 | |
| 3fwf | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.460 | |
| 3v8w | 0G2 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.460 | |
| 4ap7 | F47 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.460 | |
| 4kp5 | E1F | Carbonic anhydrase 12 | 4.2.1.1 | 0.460 | |
| 4l4x | NDP | AmphI | / | 0.460 | |
| 4u97 | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.460 | |
| 1wxy | FRK | Adenosine deaminase | 3.5.4.4 | 0.459 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.459 | |
| 3crz | FAD | Ferredoxin--NADP+ reductase | / | 0.459 | |
| 4oh4 | ANP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.459 | |
| 1gvv | 0GM | Endothiapepsin | 3.4.23.22 | 0.458 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.458 | |
| 1uml | FR4 | Adenosine deaminase | 3.5.4.4 | 0.458 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.458 | |
| 3r9d | X6B | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.458 | |
| 3tq8 | TOP | Dihydrofolate reductase | / | 0.458 | |
| 4at3 | LTI | BDNF/NT-3 growth factors receptor | 2.7.10.1 | 0.458 | |
| 4hnc | 0UT | Mandelate racemase | / | 0.458 | |
| 2blc | CP7 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.457 | |
| 2nn7 | M29 | Carbonic anhydrase 1 | 4.2.1.1 | 0.457 | |
| 2vnk | FAD | NADPH:ferredoxin reductase | / | 0.457 | |
| 3jwm | 5WB | Dihydrofolate reductase | / | 0.457 | |
| 3zy6 | GFB | GDP-fucose protein O-fucosyltransferase 1 | 2.4.1.221 | 0.457 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.457 | |
| 7dfr | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 1tez | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.456 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.456 | |
| 2w9s | TOP | Dihydrofolate reductase type 1 from Tn4003 | 1.5.1.3 | 0.456 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.456 | |
| 3clr | FAD | Electron transfer flavoprotein subunit alpha | / | 0.456 | |
| 3frd | DHF | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 3jpu | TY4 | Transcriptional activator protein LasR | / | 0.456 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.456 | |
| 4gg5 | 0J3 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.456 | |
| 1ia2 | TQ4 | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1ly3 | COG | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1zz2 | B11 | Mitogen-activated protein kinase 14 | / | 0.455 | |
| 2fsz | OHT | Estrogen receptor beta | / | 0.455 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.455 | |
| 2zax | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
| 2zza | FOL | Dihydrofolate reductase | / | 0.455 | |
| 3c1x | CKK | Hepatocyte growth factor receptor | 2.7.10.1 | 0.455 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.455 | |
| 3lfc | Z86 | Mitogen-activated protein kinase 14 | / | 0.455 | |
| 3qls | 55V | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 3sh2 | 5DR | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 3zux | TCH | Transporter | / | 0.455 | |
| 4nc3 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.455 | |
| 4oal | 245 | Cytokinin dehydrogenase 4 | / | 0.455 | |
| 4xr9 | NAD | CalS8 | / | 0.455 | |
| 1owo | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.454 | |
| 1v79 | FR7 | Adenosine deaminase | 3.5.4.4 | 0.454 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.454 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.454 | |
| 3inx | JZC | Heat shock protein HSP 90-alpha | / | 0.454 | |
| 3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.454 | |
| 3sqy | Q11 | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 3um5 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.454 | |
| 4fhb | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 4fjy | FJY | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.454 | |
| 4g09 | 0VD | Histidinol dehydrogenase | / | 0.454 | |
| 4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.454 | |
| 4xiw | AZM | Carbonic anhydrase, alpha type | / | 0.454 | |
| 2fhn | BNI | Avidin-related protein 4/5 | / | 0.453 | |
| 2q66 | ATP | Poly(A) polymerase | 2.7.7.19 | 0.453 | |
| 3bgr | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.453 | |
| 3ddw | 055 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.453 | |
| 3och | 2MX | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.453 | |
| 4ure | 1PS | Cyclohexanol dehydrogenase | / | 0.453 | |
| 4y3z | F41 | Endothiapepsin | 3.4.23.22 | 0.453 | |
| 1ao8 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1e26 | GPB | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1e7q | NAP | GDP-L-fucose synthase | / | 0.452 | |
| 1e90 | MYC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.452 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.452 | |
| 1um0 | FMN | Chorismate synthase | / | 0.452 | |
| 2j14 | GNI | Peroxisome proliferator-activated receptor delta | / | 0.452 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.452 | |
| 3sgy | 06W | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.452 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.452 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.452 | |
| 4ejg | NCT | Cytochrome P450 2A13 | 1.14.14.1 | 0.452 | |
| 4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.452 | |
| 4mq2 | 2C4 | Dual specificity tyrosine-phosphorylation-regulated kinase 1A | 2.7.12.1 | 0.452 | |
| 4rrh | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.452 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.451 | |
| 1nuu | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.451 | |
| 1owp | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.451 | |
| 1u0h | FOK | Adenylate cyclase type 2 | / | 0.451 | |
| 1u0h | FOK | Adenylate cyclase type 5 | / | 0.451 | |
| 2i9p | NAD | 3-hydroxyisobutyrate dehydrogenase, mitochondrial | 1.1.1.31 | 0.451 | |
| 2uxp | CLM | HTH-type transcriptional regulator TtgR | / | 0.451 | |
| 2yn8 | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.451 | |
| 2znp | K55 | Peroxisome proliferator-activated receptor delta | / | 0.451 | |
| 3dt1 | P40 | Mitogen-activated protein kinase 14 | / | 0.451 | |
| 3l9l | L9L | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.451 | |
| 3maa | FKP | Adenylate cyclase type 2 | / | 0.451 | |
| 3maa | FKP | Adenylate cyclase type 5 | / | 0.451 | |
| 3r33 | 6ME | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 3zxz | KRW | Hepatocyte growth factor receptor | 2.7.10.1 | 0.451 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.451 | |
| 4l4c | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 4qmp | DKI | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.451 | |
| 1pag | FMP | Antiviral protein I | 3.2.2.22 | 0.450 | |
| 1qkn | RAL | Estrogen receptor beta | / | 0.450 | |
| 1t87 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 1y57 | MPZ | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.450 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.450 | |
| 2jed | LG8 | Protein kinase C theta type | 2.7.11.13 | 0.450 | |
| 2ouy | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.450 | |
| 2wgj | VGH | Hepatocyte growth factor receptor | 2.7.10.1 | 0.450 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.450 | |
| 3f63 | GTX | Glutathione transferase GST1-4 | / | 0.450 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.450 | |
| 3ijd | C2F | Methylenetetrahydrofolate reductase | / | 0.450 | |
| 3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.450 | |
| 4n4v | 2GY | Tankyrase-1 | 2.4.2.30 | 0.450 | |
| 4o95 | 245 | Cytokinin dehydrogenase 4 | / | 0.450 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 1cs4 | FOK | Adenylate cyclase type 2 | / | 0.449 | |
| 1cs4 | FOK | Adenylate cyclase type 5 | / | 0.449 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.449 | |
| 1rdt | 570 | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 1zgy | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 2pmo | HMD | Protein kinase 7 | / | 0.449 | |
| 2w6m | OA1 | Biotin carboxylase | 6.3.4.14 | 0.449 | |
| 2zsa | ADP | Pantothenate kinase | 2.7.1.33 | 0.449 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.449 | |
| 3kdu | NKS | Peroxisome proliferator-activated receptor alpha | / | 0.449 | |
| 3koz | Z97 | D-ornithine 4,5-aminomutase subunit beta | / | 0.449 | |
| 3rtn | RTN | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 3s7a | 684 | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 3sp9 | IL2 | Peroxisome proliferator-activated receptor delta | / | 0.449 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.449 | |
| 3wd9 | QPC | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.449 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.449 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.449 | |
| 4djw | 0KP | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 4i1n | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 4nh8 | 2LC | Heat shock protein HSP 90-alpha | / | 0.449 | |
| 4qjc | IXE | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 4z64 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.449 | |
| 2dv3 | SAH | Diphthine synthase | / | 0.448 | |
| 2h9i | EAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 2pch | SAH | Diphthine synthase | / | 0.448 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.448 | |
| 2xvv | 9DN | Serum albumin | / | 0.448 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.448 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.448 | |
| 3wrm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 4kak | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 4kto | FAD | Putative isovaleryl-CoA dehydrogenase protein | / | 0.448 | |
| 4l49 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 4qkn | JMS | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.448 | |
| 4r21 | STR | Cytochrome P450 family 17 polypeptide 2 | / | 0.448 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.448 | |
| 5dbg | NAD | Iridoid synthase | 1.3.1.99 | 0.448 | |
| 1fm6 | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 1k7f | IAV | Tryptophan synthase alpha chain | / | 0.447 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1nce | CB3 | Thymidylate synthase | / | 0.447 | |
| 1pdh | FAS | p-hydroxybenzoate hydroxylase | / | 0.447 | |
| 1so2 | 666 | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.447 | |
| 2q59 | 240 | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.447 | |
| 3apf | BMW | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.447 | |
| 3ggg | NAD | Prephenate dehydrogenase | / | 0.447 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.447 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.447 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.447 | |
| 4deg | 0JJ | Hepatocyte growth factor receptor | 2.7.10.1 | 0.447 | |
| 4hyi | 1AO | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.447 | |
| 4jq7 | KJQ | Epidermal growth factor receptor | 2.7.10.1 | 0.447 | |
| 4n6h | EJ4 | Delta-type opioid receptor | / | 0.447 | |
| 4nr4 | 2LK | CREB-binding protein | / | 0.447 | |
| 1qzf | CB3 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.446 | |
| 1t85 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 1uyu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 2chw | 039 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.446 | |
| 2g78 | REA | Cellular retinoic acid-binding protein 2 | / | 0.446 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.446 | |
| 2w0b | CMW | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.446 | |
| 2wpx | ACO | Orf14 | / | 0.446 | |
| 2wuf | KEM | 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase | 3.7.1.17 | 0.446 | |
| 3cge | COA | Coenzyme A disulfide reductase | / | 0.446 | |
| 3f90 | FMN | Flavodoxin | / | 0.446 | |
| 3inw | JZB | Heat shock protein HSP 90-alpha | / | 0.446 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.446 | |
| 3own | 3OW | Renin | 3.4.23.15 | 0.446 | |
| 3q5k | D1U | Heat shock protein 83-1 | / | 0.446 | |
| 3wav | DWV | Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 | 3.1.4.39 | 0.446 | |
| 3wrj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.446 | |
| 4egn | TWO | Cytochrome P450 | / | 0.446 | |
| 4fmx | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.446 | |
| 4gll | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.446 | |
| 4h4o | 506 | Gag-Pol polyprotein | 2.7.7.49 | 0.446 | |
| 4l4d | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 4mr6 | 1K0 | Bromodomain-containing protein 2 | / | 0.446 | |
| 1dra | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1drb | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1s3y | TQT | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1zga | HMK | Isoflavone 4'-O-methyltransferase | / | 0.445 | |
| 2npa | MMB | Peroxisome proliferator-activated receptor alpha | / | 0.445 | |
| 2y4g | TIR | TamL | / | 0.445 | |
| 2z97 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 3akz | GSU | Glutamate--tRNA ligase 2 | / | 0.445 | |
| 3um8 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.445 | |
| 3zw3 | ZW3 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 4e4q | RRH | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 4en4 | ATP | Pyridoxal kinase | 2.7.1.35 | 0.445 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.445 | |
| 4ezk | 0SD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.445 | |
| 4u9a | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.445 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.445 | |
| 5ab6 | CAA | Nonspecific lipid-transfer protein, putative | / | 0.445 | |
| 1juv | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1ot7 | CHC | Bile acid receptor | / | 0.444 | |
| 1qnf | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.444 | |
| 1yrc | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 1yrd | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 2fyp | RDE | Endoplasmin | / | 0.444 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 2pml | ANP | Uncharacterized protein | / | 0.444 | |
| 2qo4 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.444 | |
| 2v59 | LZK | Biotin carboxylase | 6.3.4.14 | 0.444 | |
| 3fzn | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.444 | |
| 3njo | P2M | Abscisic acid receptor PYR1 | / | 0.444 | |
| 3srr | Q20 | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 3tda | PN0 | Cytochrome P450 2D6 | / | 0.444 | |
| 3vn2 | TLS | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 4awo | 99B | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 4fgh | 0U6 | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.444 | |
| 4jub | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.444 | |
| 4mt9 | 2D6 | Tankyrase-1 | 2.4.2.30 | 0.444 | |
| 4nmb | FAD | Bifunctional protein PutA | / | 0.444 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.443 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1ee9 | NAD | Methylenetetrahydrofolate dehydrogenase [NAD(+)] | 1.5.1.15 | 0.443 | |
| 1ezf | IN0 | Squalene synthase | 2.5.1.21 | 0.443 | |
| 1rfv | ADP | Pyridoxal kinase | 2.7.1.35 | 0.443 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 2cib | CM6 | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.443 | |
| 2el0 | SAH | Diphthine synthase | / | 0.443 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.443 | |
| 2i1v | ADP | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 | 2.7.1.105 | 0.443 | |
| 2npn | SAM | Putative cobalamin synthesis related protein | / | 0.443 | |
| 2npx | NAD | NADH peroxidase | 1.11.1.1 | 0.443 | |
| 2ohv | NHL | Glutamate racemase | / | 0.443 | |
| 2ovm | AS0 | Progesterone receptor | / | 0.443 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 2w2l | NAD | D-mandelate dehydrogenase | / | 0.443 | |
| 2x7g | PVB | SRSF protein kinase 2 | 2.7.11.1 | 0.443 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.443 | |
| 3dg8 | RJ6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.443 | |
| 3dol | GWI | Pol protein | / | 0.443 | |
| 3fwg | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 3hx4 | ANP | Calmodulin-domain protein kinase 1 | / | 0.443 | |
| 3iqz | H4M | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.443 | |
| 3l5d | BDV | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 3lsm | SFD | Pyranose 2-oxidase | / | 0.443 | |
| 3nmn | PYV | Abscisic acid receptor PYL1 | / | 0.443 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.443 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.443 | |
| 3q3c | NAD | NAD-dependent L-serine dehydrogenase | / | 0.443 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.443 | |
| 3zkp | ERB | Erythromycin C-12 hydroxylase | 1.14.13.154 | 0.443 | |
| 4ajw | VWN | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | 2.7.1.153 | 0.443 | |
| 4ap1 | NAP | Steroid monooxygenase | / | 0.443 | |
| 4dpy | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.443 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.443 | |
| 4g2f | C07 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.443 | |
| 4nj3 | 2KD | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 4u0k | 744 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 5ej4 | TD6 | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.443 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.443 | |
| 1j3k | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.442 | |
| 1ndz | FR5 | Adenosine deaminase | 3.5.4.4 | 0.442 | |
| 1rx5 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1t2b | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.442 | |
| 1t86 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.442 | |
| 2f2c | AP9 | Cyclin-dependent kinase 6 | 2.7.11.22 | 0.442 | |
| 2fgk | ATP | Alpha-hemolysin translocation ATP-binding protein HlyB | / | 0.442 | |
| 2rg5 | 279 | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 2tsc | CB3 | Thymidylate synthase | / | 0.442 | |
| 2vcx | D26 | Hematopoietic prostaglandin D synthase | / | 0.442 | |
| 2z0y | SAM | Ribosomal RNA small subunit methyltransferase E | / | 0.442 | |
| 3mvm | 39P | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 3vru | YS3 | Vitamin D3 receptor | / | 0.442 | |
| 3vt3 | VDX | Vitamin D3 receptor | / | 0.442 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 4bch | T7Z | Cyclin-dependent kinase 9 | 2.7.11.22 | 0.442 | |
| 4fjz | 4FJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 4y7c | FAD | NADPH--cytochrome P450 reductase | / | 0.442 | |
| 4yau | FAD | NADPH--cytochrome P450 reductase | / | 0.442 | |
| 5d4v | YGP | Uncharacterized protein MJ0489 | / | 0.442 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.441 | |
| 1di8 | DTQ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 1f5f | DHT | Sex hormone-binding globulin | / | 0.441 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.441 | |
| 1ju6 | LYA | Thymidylate synthase | 2.1.1.45 | 0.441 | |
| 1kp2 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.441 | |
| 1n3r | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.441 | |
| 1r0e | DFN | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.441 | |
| 1rdw | LAR | Actin, alpha skeletal muscle | / | 0.441 | |
| 1xuo | LA1 | Integrin alpha-L | / | 0.441 | |
| 1yin | CM3 | Estrogen receptor | / | 0.441 | |
| 2g2z | COZ | Malonyl CoA-acyl carrier protein transacylase | 2.3.1.39 | 0.441 | |
| 2izf | BTN | Streptavidin | / | 0.441 | |
| 2xvf | FAD | Putative flavin-containing monooxygenase | / | 0.441 | |
| 2zui | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 3g5h | YTT | Mycocyclosin synthase | 1.14.21.9 | 0.441 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.441 | |
| 3pll | F06 | Endothiapepsin | 3.4.23.22 | 0.441 | |
| 3pm0 | BHF | Cytochrome P450 1B1 | / | 0.441 | |
| 4bzn | UGX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.441 | |
| 4gxs | 0YS | Glutamate receptor 2 | / | 0.441 | |
| 4o71 | CPB | Bromodomain-containing protein 4 | / | 0.441 | |
| 4xuh | SFI | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 5dju | FMN | NPH1-2 | / | 0.441 | |
| 1buc | FAD | Acyl-CoA dehydrogenase, short-chain specific | 1.3.8.1 | 0.440 | |
| 1cbq | RE9 | Cellular retinoic acid-binding protein 2 | / | 0.440 | |
| 1d2s | DHT | Sex hormone-binding globulin | / | 0.440 | |
| 1j39 | UPG | DNA beta-glucosyltransferase | / | 0.440 | |
| 1k6t | XN1 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.440 | |
| 1nqu | RDL | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.440 | |
| 1owm | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.440 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.440 | |
| 1s7g | NAD | NAD-dependent protein deacylase 2 | / | 0.440 | |
| 1zmc | NAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.440 | |
| 2aaz | CB3 | Thymidylate synthase | 2.1.1.45 | 0.440 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.440 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.440 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
| 2wkm | PFY | Hepatocyte growth factor receptor | 2.7.10.1 | 0.440 | |
| 3d8v | UD1 | Bifunctional protein GlmU | / | 0.440 | |
| 3gnc | QQQ | Glutaryl-CoA dehydrogenase | / | 0.440 | |
| 3hk1 | B64 | Fatty acid-binding protein, adipocyte | / | 0.440 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.440 | |
| 3opd | HIE | Heat shock protein 83 | / | 0.440 | |
| 3pgi | F41 | Endothiapepsin | 3.4.23.22 | 0.440 | |
| 3sru | Q26 | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3zbn | COA | 3-ketoacyl-CoA thiolase-like protein | / | 0.440 | |
| 3zk5 | Z18 | Cytochrome P450 monooxygenase PikC | / | 0.440 | |
| 3zuy | TCH | Transporter | / | 0.440 | |
| 4awp | 99A | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 4fcr | 0TM | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.440 | |
| 4gb9 | 0WR | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 4h4q | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.440 | |
| 4hy6 | FJ1 | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 4itf | TFY | Vitamin D3 receptor | / | 0.440 | |
| 4jq8 | KJ8 | Epidermal growth factor receptor | 2.7.10.1 | 0.440 | |
| 4kko | 1RE | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 4l4f | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.440 | |
| 5dqr | FAD | 7-hydroxymethyl chlorophyll a reductase, chloroplastic | 1.17.7.2 | 0.440 |