scPDB - Distribution of Binding site Similarity values of 2w3m entry / Site 1

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
2w3m	FOL	Dihydrofolate reductase	1.5.1.3

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
2w3m	FOL	Dihydrofolate reductase	1.5.1.3	1.000
4keb	FOL	Dihydrofolate reductase	1.5.1.3	0.649
3ghw	GHW	Dihydrofolate reductase	1.5.1.3	0.626
1u72	MTX	Dihydrofolate reductase	1.5.1.3	0.618
4m6l	21V	Dihydrofolate reductase	1.5.1.3	0.608
2dhf	DZF	Dihydrofolate reductase	1.5.1.3	0.589
3gi2	GHW	Dihydrofolate reductase	1.5.1.3	0.585
4m6k	FOL	Dihydrofolate reductase	1.5.1.3	0.583
1hfr	MOT	Dihydrofolate reductase	1.5.1.3	0.582
2fzj	DH3	Dihydrofolate reductase	1.5.1.3	0.582
3ntz	3TZ	Dihydrofolate reductase	1.5.1.3	0.578
3l3r	OAG	Dihydrofolate reductase	1.5.1.3	0.577
1ohk	COP	Dihydrofolate reductase	1.5.1.3	0.565
4kfj	FOL	Dihydrofolate reductase	1.5.1.3	0.557
3n0h	TOP	Dihydrofolate reductase	1.5.1.3	0.543
1ohj	COP	Dihydrofolate reductase	1.5.1.3	0.542
2w3a	TOP	Dihydrofolate reductase	1.5.1.3	0.539
1dls	MTX	Dihydrofolate reductase	1.5.1.3	0.534
3k45	51P	Dihydrofolate reductase	1.5.1.3	0.533
1kms	LIH	Dihydrofolate reductase	1.5.1.3	0.532
1dhf	FOL	Dihydrofolate reductase	1.5.1.3	0.530
3gyf	51P	Dihydrofolate reductase	1.5.1.3	0.530
3nu0	3TU	Dihydrofolate reductase	1.5.1.3	0.529
4eil	FOL	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.529
3ghv	GHC	Dihydrofolate reductase	1.5.1.3	0.528
3nrr	D16	Bifunctional dihydrofolate reductase-thymidylate synthase	/	0.528
1drf	FOL	Dihydrofolate reductase	1.5.1.3	0.522
4ky4	04J	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.521
1hfq	MOT	Dihydrofolate reductase	1.5.1.3	0.518
1u70	MTX	Dihydrofolate reductase	1.5.1.3	0.518
1hfp	MOT	Dihydrofolate reductase	1.5.1.3	0.508
1pd9	CO4	Dihydrofolate reductase	1.5.1.3	0.508
4kd7	9DR	Dihydrofolate reductase	1.5.1.3	0.508
1mvt	DTM	Dihydrofolate reductase	1.5.1.3	0.503
1kmv	LII	Dihydrofolate reductase	1.5.1.3	0.502
1s3u	TQD	Dihydrofolate reductase	1.5.1.3	0.495
3d80	Q22	Dihydrofolate reductase	1.5.1.3	0.492
3nxt	D2E	Dihydrofolate reductase	1.5.1.3	0.488
4kak	06U	Dihydrofolate reductase	1.5.1.3	0.483
3nxv	D2F	Dihydrofolate reductase	1.5.1.3	0.473
1pd8	CO4	Dihydrofolate reductase	1.5.1.3	0.466
4dpd	DHF	Bifunctional dihydrofolate reductase-thymidylate synthase	/	0.465
1mvs	DTM	Dihydrofolate reductase	1.5.1.3	0.464
4kbn	25U	Dihydrofolate reductase	1.5.1.3	0.461
4kfj	1R0	Dihydrofolate reductase	1.5.1.3	0.459
1s3v	TQD	Dihydrofolate reductase	1.5.1.3	0.455
4ixe	IXE	Dihydrofolate reductase	1.5.1.3	0.455
3qly	55V	Uncharacterized protein	/	0.454
3nxr	D2D	Dihydrofolate reductase	1.5.1.3	0.452
2vbp	VB1	Isopenicillin N synthase	1.21.3.1	0.451
2y6f	M9F	Isopenicillin N synthase	1.21.3.1	0.450
1blz	ACV	Isopenicillin N synthase	1.21.3.1	0.448
2fm5	M99	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.445
3eig	MTX	Dihydrofolate reductase	1.5.1.3	0.443
3s7a	684	Dihydrofolate reductase	1.5.1.3	0.441