sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2w2x | GSP | Ras-related C3 botulinum toxin substrate 2 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2w2x | GSP | Ras-related C3 botulinum toxin substrate 2 | / | 1.000 | |
| 1kmq | GNP | Transforming protein RhoA | / | 0.600 | |
| 2gcp | GSP | Rho-related GTP-binding protein RhoC | / | 0.569 | |
| 1cxz | GSP | Transforming protein RhoA | / | 0.567 | |
| 1yzq | GNP | Ras-related protein Rab-6A | / | 0.567 | |
| 3eg5 | GNP | Cell division control protein 42 homolog | / | 0.560 | |
| 1m7b | GTP | Rho-related GTP-binding protein RhoE | / | 0.554 | |
| 4js0 | GNP | Cell division control protein 42 homolog | / | 0.546 | |
| 2fju | GSP | Ras-related C3 botulinum toxin substrate 1 | / | 0.543 | |
| 1a2b | GSP | Transforming protein RhoA | / | 0.542 | |
| 3a58 | GNP | GTP-binding protein RHO1 | / | 0.542 | |
| 4xoi | GTP | Transforming protein RhoA | / | 0.542 | |
| 2ov2 | GCP | Ras-related C3 botulinum toxin substrate 3 | / | 0.540 | |
| 3kz1 | GSP | Transforming protein RhoA | / | 0.536 | |
| 4gzm | GSP | Ras-related C3 botulinum toxin substrate 1 | / | 0.536 | |
| 1xtr | GNP | GTP-binding protein Rheb | / | 0.533 | |
| 1zc4 | GNP | Ras-related protein Ral-A | / | 0.533 | |
| 2gil | GTP | Ras-related protein Rab-6A | / | 0.533 | |
| 1gwn | GTP | Rho-related GTP-binding protein RhoE | / | 0.529 | |
| 3oes | GNP | GTPase RhebL1 | / | 0.529 | |
| 3tnf | GNP | Ras-related protein Rab-8A | / | 0.527 | |
| 1g17 | GNP | Ras-related protein SEC4 | / | 0.518 | |
| 1zc3 | GNP | Ras-related protein Ral-A | / | 0.512 | |
| 2qme | GCP | Ras-related C3 botulinum toxin substrate 3 | / | 0.511 | |
| 3bbp | GTP | Ras-related protein Rab-6A | / | 0.507 | |
| 3e5h | GNP | Ras-related protein Rab-28 | / | 0.505 | |
| 5dha | GNP | GTP-binding nuclear protein Ran | / | 0.505 | |
| 2ffq | GSP | Ras-related protein Rab-6B | / | 0.503 | |
| 4dvg | GSP | Rho family GTPase | / | 0.502 | |
| 3sbe | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.500 | |
| 1xts | GTP | GTP-binding protein Rheb | / | 0.499 | |
| 4nyi | GNP | GTPase HRas | / | 0.497 | |
| 5hpy | GDP | Transforming protein RhoA | / | 0.496 | |
| 3rab | GNP | Ras-related protein Rab-3A | / | 0.494 | |
| 1mh1 | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.493 | |
| 3v4f | GNP | GTPase HRas | / | 0.491 | |
| 1t91 | GTP | Ras-related protein Rab-7a | / | 0.490 | |
| 3ddc | GNP | GTPase HRas | / | 0.490 | |
| 1zbd | GTP | Ras-related protein Rab-3A | / | 0.489 | |
| 1s1c | GNP | Transforming protein RhoA | / | 0.488 | |
| 2cls | GTP | Rho-related GTP-binding protein Rho6 | / | 0.488 | |
| 5b2z | GNP | GTPase HRas | / | 0.487 | |
| 3oiv | GNP | GTPase HRas | / | 0.485 | |
| 3lbn | GNP | GTPase HRas | / | 0.483 | |
| 1vg8 | GNP | Ras-related protein Rab-7a | / | 0.482 | |
| 4dlt | GNP | GTPase HRas | / | 0.481 | |
| 1e96 | GTP | Ras-related C3 botulinum toxin substrate 1 | / | 0.480 | |
| 3sbd | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.478 | |
| 2zet | GTP | Ras-related protein Rab-27B | / | 0.477 | |
| 3nbz | GTP | GTP-binding nuclear protein Ran | / | 0.476 | |
| 4gzl | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.475 | |
| 1yhn | GTP | Ras-related protein Rab-7a | / | 0.474 | |
| 3tgp | GNP | GTPase HRas | / | 0.474 | |
| 3tkl | GTP | Ras-related protein Rab-1A | / | 0.474 | |
| 4qxa | GTP | Ras-related protein Rab-9A | / | 0.474 | |
| 3law | GNP | Ras-related protein Rab-7a | / | 0.473 | |
| 2rge | GNP | GTPase HRas | / | 0.472 | |
| 1z2c | GNP | Rho-related GTP-binding protein RhoC | / | 0.471 | |
| 4nyj | GNP | GTPase HRas | / | 0.471 | |
| 4cym | GCP | Ras-related protein Rab-32 | / | 0.468 | |
| 3a6p | GTP | GTP-binding nuclear protein Ran | / | 0.466 | |
| 4lhw | GNP | Ras-related protein Rab-8A | / | 0.464 | |
| 5jlj | GNP | GTP-binding nuclear protein Ran | / | 0.464 | |
| 3oiu | GNP | GTPase HRas | / | 0.461 | |
| 1ibr | GNP | GTP-binding nuclear protein Ran | / | 0.459 | |
| 3bc1 | GNP | Ras-related protein Rab-27A | / | 0.459 | |
| 3rs7 | GNP | GTPase HRas | / | 0.459 | |
| 3th5 | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.459 | |
| 3kko | GNP | Ras-related protein M-Ras | / | 0.458 | |
| 3w3z | GTP | GTP-binding nuclear protein Ran | / | 0.458 | |
| 4o25 | GTP | GTP-binding protein Rheb | / | 0.458 | |
| 2x19 | GTP | GTP-binding nuclear protein GSP1/CNR1 | / | 0.457 | |
| 4kvg | GTP | Ras-related protein Rap-1A | / | 0.457 | |
| 3i3s | GNP | GTPase HRas | / | 0.456 | |
| 4oi2 | ADP | Protein clpf-1 | / | 0.455 | |
| 2c5l | GTP | GTPase HRas | / | 0.453 | |
| 3rs5 | GNP | GTPase HRas | / | 0.453 | |
| 4k81 | GTP | GTPase HRas | / | 0.451 | |
| 2fe4 | GDP | Ras-related protein Rab-6B | / | 0.450 | |
| 4hdo | GNP | Ras-related protein Rap-1b | / | 0.449 | |
| 2rgg | GNP | GTPase HRas | / | 0.448 | |
| 2rgc | GNP | GTPase HRas | / | 0.447 | |
| 4dso | GSP | GTPase KRas | / | 0.446 | |
| 4mit | GTP | Rho-related protein racC | / | 0.443 | |
| 3tso | GNP | Ras-related protein Rab-25 | / | 0.441 | |
| 2rgb | GNP | GTPase HRas | / | 0.440 |