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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2vo7M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.11

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2vo7M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.111.000
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.648
2ojf4PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.636
2c1bCQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.634
2f7z6EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.617
2uzuL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.617
2vo6M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.617
2f7e2EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.614
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.605
2uzwSS4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.601
1q8tY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.595
1sveI01cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.585
2oh02PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.585
1vebI05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.582
3vqhIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.581
1ydtIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.570
1xh5R68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.567
2gu8796cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.560
2c1aI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.557
2uw0GVKcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.555
2jdtI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.554
3ow3SMYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.554
2vo3M04cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.553
1xh6R94cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.545
3zo4QWIcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.543
1xhaR68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.541
1xh8R55cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.538
1svhI08cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.536
1svgI04cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.535
1xh7R96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.531
2uzvSS5cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.529
1xh9R69cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.528
4axaRKDcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.528
3e8cG96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.525
2uztSS3cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.519
3bwjARXcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.516
2uw5GVNcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.515
1bx6BA1cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.514
2vo0M03cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.509
2uw7GVPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.507
1xh4R69cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.503
3e8eG98cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.492
2gnhH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.487
3aglA03cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.486
1rejB1LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.483
1ydrIQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.481
1j1cADPGlycogen synthase kinase-3 beta2.7.11.260.477
1q8uH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.477
3l9mL9McAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.477
4gv10XZRAC-alpha serine/threonine-protein kinase2.7.11.10.474
4oh4ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.469
2gnfY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.464
2gnlH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.459
3kkvB99cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.459
4iazADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.458
4qnyANPMitogen activated protein kinase, putative/0.457
1jbpADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.451
3zo1SIJcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.451
4iacACPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.449
4xw4ANPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.449
4fv5EK9Mitogen-activated protein kinase 12.7.11.240.448
2uvzGVJcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.446
4fv6E57Mitogen-activated protein kinase 12.7.11.240.446
4iayADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.443
4iakADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.442
4mk029XBeta-adrenergic receptor kinase 12.7.11.150.442
2jdvL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440
3nieANPMitogen-activated protein kinase/0.440
3x2wATPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440