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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2vo3M04cAMP-dependent protein kinase catalytic subunit alpha2.7.11.11

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2vo3M04cAMP-dependent protein kinase catalytic subunit alpha2.7.11.111.000
2uw0GVKcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.632
2vo0M03cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.626
2vo7M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.619
1xh5R68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.601
2vo6M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.593
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.589
2vnwM01cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.585
2oh02PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.575
2c1aI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.565
2jdtI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.558
2f7e2EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.557
2gu8796cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.557
1xh9R69cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.555
2ojf4PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.555
4axaRKDcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.555
1vebI05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.554
2uzvSS5cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.554
2uw7GVPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.549
1xh6R94cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.547
2uzuL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.543
3e8eG98cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.543
1q8tY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.542
2f7z6EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.541
1xh7R96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.540
1xhaR68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.540
3vqhIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.538
3zo4QWIcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.536
2uzwSS4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.533
1xh8R55cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.525
3zo1SIJcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.524
1sveI01cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.523
1ydtIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.523
2gnlH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.514
1svhI08cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.510
3e8cG96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.509
1rejB1LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.506
1bx6BA1cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.503
1q8uH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.501
3dfcANPDeath-associated protein kinase 12.7.11.10.501
4gv10XZRAC-alpha serine/threonine-protein kinase2.7.11.10.498
2uw5GVNcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.493
1q8wM77cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.489
2c1bCQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.489
1xh4R69cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.485
3ow3SMYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.484
4ekl0RFRAC-alpha serine/threonine-protein kinase2.7.11.10.482
1jklANPDeath-associated protein kinase 12.7.11.10.480
3kkvB99cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.473
3aglA03cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.472
2gnfY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.471
2uztSS3cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.470
2y9qANPMitogen-activated protein kinase 12.7.11.240.466
4jik1KOSerine/threonine-protein kinase Chk12.7.11.10.466
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.465
3mvhWFERAC-alpha serine/threonine-protein kinase2.7.11.10.465
1ydrIQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.464
2uvzGVJcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.464
5av2KMPDeath-associated protein kinase 12.7.11.10.462
1svgI04cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.459
5av3KMPDeath-associated protein kinase 12.7.11.10.459
3bwjARXcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.458
3v5w8PRBeta-adrenergic receptor kinase 12.7.11.150.458
2uw6GVOcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.456
3gu6ADPDeath-associated protein kinase 12.7.11.10.452
2ijmADPFocal adhesion kinase 12.7.10.20.451
4j95ACPFibroblast growth factor receptor 2/0.451
2gnhH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.450
2j0lANPFocal adhesion kinase 12.7.10.20.450
2yaaATPDeath-associated protein kinase 2/0.450
4mk029XBeta-adrenergic receptor kinase 12.7.11.150.450
4fv5EK9Mitogen-activated protein kinase 12.7.11.240.448
3zokNAD3-dehydroquinate synthase, chloroplastic4.2.3.40.446
1j1bANPGlycogen synthase kinase-3 beta2.7.11.260.442
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.442
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440