scPDB - Distribution of Binding site Similarity values of 2vle entry / Site 4

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
2vle	DZN	Aldehyde dehydrogenase, mitochondrial	1.2.1.3

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
2vle	DZN	Aldehyde dehydrogenase, mitochondrial	1.2.1.3	1.000
3inj	BXB	Aldehyde dehydrogenase, mitochondrial	1.2.1.3	0.533
3inl	BXB	Aldehyde dehydrogenase, mitochondrial	1.2.1.3	0.524
3v94	WYQ	Phosphodiesterase	/	0.452
4fr8	TNG	Aldehyde dehydrogenase, mitochondrial	1.2.1.3	0.446