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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2vdyHCYCorticosteroid-binding globulin

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
2vdyHCYCorticosteroid-binding globulin/1.000
4bb2STRCorticosteroid-binding globulin/0.604
4c49HCYCorticosteroid-binding globulin/0.578
2v95HCYCorticosteroid-binding globulin/0.552
1re0AFBADP-ribosylation factor 1/0.524
1re0AFBARF guanine-nucleotide exchange factor 1/0.524
3gncQQQGlutaryl-CoA dehydrogenase/0.521
1zdwFLVPrenyltransferase/0.514
3eon341Glutaryl-CoA dehydrogenase/0.510
4cdmFO1Deoxyribodipyrimidine photolyase/0.509
1pwyAC2Purine nucleoside phosphorylase2.4.2.10.507
1p33MTXPteridine reductase 11.5.1.330.503
3hxbBD5Geranylgeranyl transferase type-2 subunit beta2.5.1.600.503
4gtt7TQGeranylgeranyl transferase type-2 subunit beta2.5.1.600.500
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.499
3qizQI2Botulinum neurotoxin type A3.4.24.690.499
3ziaADPATP synthase subunit beta, mitochondrial3.6.3.140.498
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.496
3gyuDL7Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.496
3zkyWT4Isopenicillin N synthase1.21.3.10.496
2ea4F79Methionine aminopeptidase 2/0.495
3cmfPDN3-oxo-5-beta-steroid 4-dehydrogenase/0.495
4qzuRTLRetinol-binding protein 2/0.495
1obnASVIsopenicillin N synthase1.21.3.10.494
2w6zL21Biotin carboxylase6.3.4.140.494
3c14FOKAdenylate cyclase type 2/0.494
3c14FOKAdenylate cyclase type 5/0.494
1rsgFADPolyamine oxidase FMS1/0.493
3fktSIIBeta-secretase 13.4.23.460.493
4jtqFLPAldo-keto reductase family 1 member C2/0.493
3pz3PZ3Geranylgeranyl transferase type-2 subunit beta2.5.1.600.492
4e0u0MVCyclic dipeptide N-prenyltransferase/0.492
2fb8215Serine/threonine-protein kinase B-raf2.7.11.10.491
3ggs2FDPurine nucleoside phosphorylase2.4.2.10.491
3ppkFNISerine/threonine-protein kinase B-raf2.7.11.10.491
3uzwNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.491
3uzxAOX3-oxo-5-beta-steroid 4-dehydrogenase/0.491
2ed3SAHDiphthine synthase/0.490
2wo7ASVIsopenicillin N synthase1.21.3.10.490
4jsr1NQNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.490
3fsjD7KBenzoylformate decarboxylase4.1.1.70.489
3nxyD2HDihydrofolate reductase1.5.1.30.489
4q0kGA3Phytohormone-binding protein/0.489
1pq944BOxysterols receptor LXR-beta/0.488
3mj4URMUDP-galactopyranose mutase/0.488
4wda2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.488
2h63NAPBiliverdin reductase A1.3.1.240.487
3hxdBD7Geranylgeranyl transferase type-2 subunit beta2.5.1.600.487
3gl2D3MDdmC/0.486
3gwfNAPCyclohexanone monooxygenase/0.486
4b12C23Glycylpeptide N-tetradecanoyltransferase/0.486
4bfxZVXPantothenate kinase2.7.1.330.486
4eqrCOACoenzyme A disulfide reductase/0.486
2xvfFADPutative flavin-containing monooxygenase/0.485
3q9bB3NAcetylpolyamine amidohydrolase/0.485
3vf60H6Glucokinase2.7.1.20.484
4j531J4Serine/threonine-protein kinase PLK12.7.11.210.484
6stdMS2Scytalone dehydratase4.2.1.940.484
1dnpMHFDeoxyribodipyrimidine photo-lyase4.1.99.30.483
1cjuFOKAdenylate cyclase type 2/0.482
1cjuFOKAdenylate cyclase type 5/0.482
1nquRDL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.482
1upw444Oxysterols receptor LXR-beta/0.482
4bbhYBNGlycylpeptide N-tetradecanoyltransferase/0.482
1hb3SCVIsopenicillin N synthase1.21.3.10.481
1s9dAFBCytohesin-2/0.481
1s9dAFBADP-ribosylation factor 1/0.481
3ekuCY9Actin-5C/0.481
3p8iFMNPentaerythritol tetranitrate reductase/0.481
4ise1FWGlucokinase2.7.1.20.481
4isg1FYGlucokinase2.7.1.20.481
4xbfFADLysine-specific histone demethylase 1A10.481
1lkeDOGBilin-binding protein/0.480
1qbqHFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.480
1qbqHFPProtein farnesyltransferase subunit beta2.5.1.580.480
2q7oIMHPurine nucleoside phosphorylase2.4.2.10.480
2vn1FK5Peptidylprolyl isomerase/0.480
2yneYNEGlycylpeptide N-tetradecanoyltransferase/0.480
3lkhLT6Genome polyprotein2.7.7.480.480
3wqmB29Diterpene synthase3.1.7.80.480
4ttiFMCPurine nucleoside phosphorylase DeoD-type/0.480
2gvdFKPAdenylate cyclase type 2/0.479
2gvdFKPAdenylate cyclase type 5/0.479
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.479
2rehFADNitroalkane oxidase1.7.3.10.478
2vbpVB1Isopenicillin N synthase1.21.3.10.478
3a1cACPProbable copper-exporting P-type ATPase A3.6.3.540.478
3kslSZHProtein farnesyltransferase subunit beta2.5.1.580.478
4bfzZVZPantothenate kinase2.7.1.330.478
1k4gAIQQueuine tRNA-ribosyltransferase2.4.2.290.477
1lnmDTXBilin-binding protein/0.477
2fpcSCGStrictosidine synthase4.3.3.20.477
2fvlNAPAldo-keto reductase family 1 member C41.1.1.2250.477
2ourCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.477
2xviFADPutative flavin-containing monooxygenase/0.477
3h3r14HCollagen type IV alpha-3-binding protein/0.477
3uzxAOM3-oxo-5-beta-steroid 4-dehydrogenase/0.477
4gts7TPGeranylgeranyl transferase type-2 subunit beta2.5.1.600.477
1cjtFOKAdenylate cyclase type 2/0.476
1cjtFOKAdenylate cyclase type 5/0.476
1nqvLMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.476
1tysDHFThymidylate synthase/0.476
1ycgFMNNitric oxide reductase10.476
2gv8NDPThiol-specific monooxygenase1.14.130.476
3h3t16HCollagen type IV alpha-3-binding protein/0.476
1v3q2DIPurine nucleoside phosphorylase2.4.2.10.475
2hxzH7JCathepsin S3.4.22.270.475
2y66N04UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.475
3i6qNDPPutative leucoanthocyanidin reductase 1/0.475
3otbDGTProbable tRNA(His) guanylyltransferase2.7.7.790.475
3v2uATPProtein GAL3/0.475
4a959MTGlycylpeptide N-tetradecanoyltransferase/0.475
4f1l0RYPoly [ADP-ribose] polymerase 142.4.2.300.475
4psbGA3Cytokinin-specific binding protein/0.475
1cjvFOKAdenylate cyclase type 2/0.474
1cjvFOKAdenylate cyclase type 5/0.474
1ro98BRcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.474
1rzuADPGlycogen synthase 12.4.1.210.474
1so2666cGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.474
2p8uCOAHydroxymethylglutaryl-CoA synthase, cytoplasmic2.3.3.100.474
4gtv7TRGeranylgeranyl transferase type-2 subunit beta2.5.1.600.474
4l8u9AZSerum albumin/0.474
4la7A1OAbscisic acid receptor PYL2/0.474
4uugPXGBranched-chain amino acid aminotransferase, putative/0.474
1lcwSHMStreptavidin/0.473
1ndzFR5Adenosine deaminase3.5.4.40.473
2vteIK4UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.473
3iktNADRedox-sensing transcriptional repressor Rex/0.473
3jq6DX1Pteridine reductase, putative/0.473
3vkjFNRIsopentenyl-diphosphate delta-isomerase/0.473
3zbsOVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.473
1e2nRCAThymidine kinase/0.472
1x8lOXRRetinol dehydratase/0.472
2ddoATPPyridoxine/pyridoxal/pyridoxamine kinase/0.472
2jfhLK1UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.472
3nx2FERFerulic acid decarboxylase/0.472
3qeoLLTDeoxycytidine kinase2.7.1.740.472
4ddrMMVDihydrofolate reductase1.5.1.30.472
4iaq2GM5-hydroxytryptamine receptor 1B/0.472
2r2lPB9Protein farnesyltransferase subunit beta2.5.1.580.471
2vcmM11Isopenicillin N synthase1.21.3.10.471
3bi2FADPolyamine oxidase FMS1/0.471
3nu03TUDihydrofolate reductase1.5.1.30.471
4a30QMIGlycylpeptide N-tetradecanoyltransferase/0.471
4bfvZVVPantothenate kinase2.7.1.330.471
4eh9IRGMitogen-activated protein kinase 14/0.471
4m9aFDAAcyl-CoA dehydrogenase/0.471
4u150HKMuscarinic acetylcholine receptor M3/0.471
1hfqMOTDihydrofolate reductase1.5.1.30.470
1wp4NDP3-hydroxyisobutyrate dehydrogenase/0.470
2ea2F77Methionine aminopeptidase 2/0.470
2r5nTPPTransketolase 1/0.470
2y01Y00Beta-1 adrenergic receptor/0.470
3hdyGDUUDP-galactopyranose mutase/0.470
3iogSDFMetallo-beta-lactamase type 2/0.470
3jq7DX2Pteridine reductase, putative/0.470
4brdANPEctonucleoside triphosphate diphosphohydrolase I/0.470
4dan2FAPurine nucleoside phosphorylase DeoD-type2.4.2.10.470
4iraFAD4-hydroxyphenylacetate 3-monooxygenase/0.470
1b87ACOAac(6')-Ii protein/0.469
1jraFADFAD-linked sulfhydryl oxidase ERV21.8.3.20.469
1lc3NADBiliverdin reductase A1.3.1.240.469
1osvCHCBile acid receptor/0.469
1qjfACSIsopenicillin N synthase1.21.3.10.469
1rftPXMPyridoxal kinase2.7.1.350.469
2bt4CA23-dehydroquinate dehydratase4.2.1.100.469
2gjnFMNNitronate monooxygenase1.13.12.160.469
2h447CAcGMP-specific 3',5'-cyclic phosphodiesterase/0.469
2v59LZKBiotin carboxylase6.3.4.140.469
3atyFMNProstaglandin F2a synthase/0.469
3bk2U5PRibonuclease J/0.469
3c3xNAPEugenol synthase 11.1.1.3180.469
3jsxCC2NAD(P)H dehydrogenase [quinone] 11.6.5.20.469
3ske054Genome polyprotein2.7.7.480.469
3uzzTES3-oxo-5-beta-steroid 4-dehydrogenase/0.469
3zhuTD8Multifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.469
4b4vL34Bifunctional protein FolD/0.469
4dk70KSOxysterols receptor LXR-beta/0.469
4jq2SUZAldo-keto reductase family 1 member C2/0.469
4lg5A1OAbscisic acid receptor PYL2/0.469
1culFOKAdenylate cyclase type 2/0.468
1culFOKAdenylate cyclase type 5/0.468
1sreHABStreptavidin/0.468
1uagUMAUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.468
1xuoLA1Integrin alpha-L/0.468
1ygjRMCPyridoxal kinase2.7.1.350.468
2h3wHC5Carnitine O-acetyltransferase2.3.1.70.468
2hzqSTRApolipoprotein D/0.468
2iviACWIsopenicillin N synthase1.21.3.10.468
3q7fED2Uncharacterized protein/0.468
4g34924Eukaryotic translation initiation factor 2-alpha kinase 32.7.11.10.468
4lrrCF9Thymidylate synthase/0.468
4o7uTHFThymidylate synthase/0.468
4qa0SHHHistone deacetylase 83.5.1.980.468
5fd8A5APutative carboxypeptidase yocD/0.468
5stdUNNScytalone dehydratase4.2.1.940.468
1pz1NAPGeneral stress protein 69/0.467
1w19T5P6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.467
2iu8UD1UDP-3-O-acylglucosamine N-acyltransferase2.3.10.467
2qw8NAPEugenol synthase 11.1.1.3180.467
2r0pK2CPutative FAD-monooxygenase/0.467
2rtdBTNStreptavidin/0.467
2tscCB3Thymidylate synthase/0.467
2vqoTFGHistone deacetylase 43.5.1.980.467
3b04OOPIsopentenyl-diphosphate delta-isomerase/0.467
3g1rFIT3-oxo-5-beta-steroid 4-dehydrogenase/0.467
3uzzASD3-oxo-5-beta-steroid 4-dehydrogenase/0.467
4b13X25Glycylpeptide N-tetradecanoyltransferase/0.467
4bftZVTPantothenate kinase2.7.1.330.467
4l4xNDPAmphI/0.467
4uymVOR14-alpha sterol demethylase Cyp51B/0.467
1el4CTZObelin/0.466
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.466
1x1bSAHC-20 methyltransferase/0.466
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.466
2fjdSFDAdenylylsulfate reductase, subunit A (AprA)/0.466
2xpc051UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.466
2y60M8FIsopenicillin N synthase1.21.3.10.466
2zfr46UProthrombin3.4.21.50.466
3bv7NAP3-oxo-5-beta-steroid 4-dehydrogenase/0.466
3k1wBFXRenin3.4.23.150.466
4c6zTLE3-oxoacyl-ACP synthase/0.466
4jln18VDeoxycytidine kinase2.7.1.740.466
4rgsV55Repressor protein/0.466
4ubtCOASteroid 3-ketoacyl-CoA thiolase/0.466
1jnrFADAdenylylsulfate reductase, subunit A (AprA)/0.465
1r8qAFBCytohesin-2/0.465
1r8qAFBADP-ribosylation factor 1/0.465
2h94FADLysine-specific histone demethylase 1A10.465
2xveFADPutative flavin-containing monooxygenase/0.465
2y67N21UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.465
2yozOVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.465
3gmd2M3Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.465
3qiyQI1Botulinum neurotoxin type A3.4.24.690.465
4dbc3QPAspartate aminotransferase2.6.1.10.465
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.465
4hu1V13Carbonic anhydrase 134.2.1.10.465
1mczRMNBenzoylformate decarboxylase4.1.1.70.464
1rx5DDFDihydrofolate reductase1.5.1.30.464
1u1f183Uridine phosphorylase2.4.2.30.464
1yhjR6CPyridoxal kinase2.7.1.350.464
2v57PRLTetR family transcriptional regulator/0.464
2xdaJPS3-dehydroquinate dehydratase4.2.1.100.464
2yp0OVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.464
3p67FMNPentaerythritol tetranitrate reductase/0.464
3rdqDTBStreptavidin/0.464
3tfjTHGDimethylsulfonioproprionate demethylase DmdA2.1.1.2690.464
3zv7NHGAcetylcholinesterase3.1.1.70.464
4bb3KKAIsopenicillin N synthase1.21.3.10.464
4brgGNPEctonucleoside triphosphate diphosphohydrolase I/0.464
4kxjP34Nucleoprotein/0.464
4wo5324Serine/threonine-protein kinase B-raf2.7.11.10.464
1enoNADEnoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic1.3.1.90.463
1qiqACCIsopenicillin N synthase1.21.3.10.463
1srgMHBStreptavidin/0.463
2fxuBIDActin, alpha skeletal muscle/0.463
2lfoGCHFatty acid-binding protein, liver/0.463
2uupLK4UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.463
2vz0D64Pteridine reductase/0.463
2wd8VGFPteridine reductase/0.463
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.463
3qviK95HAP protein/0.463
4b144XBGlycylpeptide N-tetradecanoyltransferase/0.463
4dvi2IWTankyrase-12.4.2.300.463
4jlj1NMDeoxycytidine kinase2.7.1.740.463
4jtrIZPAldo-keto reductase family 1 member C2/0.463
4pnmNU1Tankyrase-22.4.2.300.463
1m2xMCOMetallo-beta-lactamase type 2/0.462
1qtiGNTAcetylcholinesterase3.1.1.70.462
1tkaN3TTransketolase 12.2.1.10.462
1wv4FMNPyridoxine/pyridoxamine 5'-phosphate oxidase/0.462
2e95B75Geranylgeranyl pyrophosphate synthase/0.462
2fs4PZ1Renin3.4.23.150.462
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.462
2xlpFADPutative flavin-containing monooxygenase/0.462
2y71CB63-dehydroquinate dehydratase4.2.1.100.462
3h3qH13Collagen type IV alpha-3-binding protein/0.462
3prfFP3Serine/threonine-protein kinase B-raf2.7.11.10.462
4b64NAPL-ornithine N(5)-monooxygenase/0.462
4fm80UQBeta-secretase 13.4.23.460.462
4iarERM5-hydroxytryptamine receptor 1B/0.462
4zzjCNANAD-dependent protein deacetylase sirtuin-13.5.10.462
5c1mCLRMu-type opioid receptor/0.462
5dv2C5PCCR4-NOT transcription complex subunit 6-like3.1.13.40.462
1c7oPPGHemolysin/0.461
1cjkFOKAdenylate cyclase type 2/0.461
1cjkFOKAdenylate cyclase type 5/0.461
1pq6965Oxysterols receptor LXR-beta/0.461
1qs2NADVip2Ac/0.461
1rt9IMHPurine nucleoside phosphorylase2.4.2.10.461
2a1hGBNBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.461
2a4nCOAAac(6')-Ii protein/0.461
2rhrEMOPutative ketoacyl reductase1.3.10.461
3cr0809Wee1-like protein kinase2.7.10.20.461
3d5qT30Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.461
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.461
3gytDL4Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.461
3mjrAC2Deoxycytidine kinase2.7.1.740.461
3mytEQUSteroid Delta-isomerase5.3.3.10.461
3n76CA23-dehydroquinate dehydratase4.2.1.100.461
3phcIM5Purine nucleoside phosphorylase/0.461
4f4dCHDFerrochelatase, mitochondrial4.99.1.10.461
4kc1WS1Histo-blood group ABO system transferase/0.461
4ku7PCGcGMP-dependent protein kinase 12.7.11.120.461
4rh10TTSpore photoproduct lyase/0.461
5kp2COA3-oxoacyl-[acyl-carrier-protein] synthase 3 protein 2/0.461
1cf3FADGlucose oxidase1.1.3.40.460
1ekoI84Aldose reductase1.1.1.210.460
1fx9MJIPhospholipase A2, major isoenzyme3.1.1.40.460
1hb1OCVIsopenicillin N synthase1.21.3.10.460
1ihiIU5Aldo-keto reductase family 1 member C2/0.460
1oltSAMOxygen-independent coproporphyrinogen III oxidase/0.460
1r2jFADFkbI/0.460
2d81RB3Poly(3-hydroxybutyrate) depolymerase/0.460
2izfBTNStreptavidin/0.460
2o7pNAPRiboflavin biosynthesis protein RibD/0.460
2qpyDHTAndrogen receptor/0.460
2wyaHMGHydroxymethylglutaryl-CoA synthase, mitochondrial2.3.3.100.460
3biz61EWee1-like protein kinase2.7.10.20.460
3c72CX1Geranylgeranyl transferase type-2 subunit beta2.5.1.600.460
3zoiM2WIsopenicillin N synthase1.21.3.10.460
4b2gV1NUncharacterized protein/0.460
1fdtESTEstradiol 17-beta-dehydrogenase 11.1.1.620.459
1m67BOAGlycerol-3-phosphate dehydrogenase [NAD(+)], glycosomal1.1.1.80.459
1mxfMTXPutative pteridine reductase 2/0.459
1pwmFIDAldose reductase1.1.1.210.459
1toiHCIAspartate aminotransferase2.6.1.10.459
1xddAAYIntegrin alpha-L/0.459
1xuzMMNCapsule biosynthesis protein/0.459
2fw3BUICarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.459
2re8GSUGlutamine--tRNA ligase6.1.1.180.459
3f3y4OABile salt sulfotransferase2.8.2.140.459
3jqgAX6Pteridine reductase, putative/0.459
3nxrD2DDihydrofolate reductase1.5.1.30.459
3o4rNAPDehydrogenase/reductase SDR family member 41.1.1.1840.459
3sqzCOAPutative hydroxymethylglutaryl-CoA synthase/0.459
4b1fKRHGlutamate racemase/0.459
4dbs0HVAldo-keto reductase family 1 member C3/0.459
4jvnYUGEstrogen sulfotransferase2.8.2.40.459
4mlp2CXCryptochrome-2/0.459
4oztP1AEcdysone receptor, putative/0.459
5cb3APRO-acetyl-ADP-ribose deacetylase/0.459
2yczI32Beta-1 adrenergic receptor/0.459
1efzPRFQueuine tRNA-ribosyltransferase2.4.2.290.458
1sd2MTHS-methyl-5'-thioadenosine phosphorylase/0.458
1sojIBMcGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.458
1tl7FOKAdenylate cyclase type 2/0.458
1tl7FOKAdenylate cyclase type 5/0.458
1u65CP0Acetylcholinesterase3.1.1.70.458
1vkgCRIHistone deacetylase 83.5.1.980.458
2j9fTHV2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial1.2.4.40.458
2j9fTHV2-oxoisovalerate dehydrogenase subunit beta, mitochondrial1.2.4.40.458
2uuoLK3UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.458
2x7hPFNProstaglandin reductase 310.458
3b9oFMNAlkane monoxygenase/0.458
3g70A5TRenin3.4.23.150.458
3u9fCLMChloramphenicol acetyltransferase2.3.1.280.458
3w78CBDFMN-dependent NADH-azoreductase/0.458
3x03ANPPhosphatidylinositol 5-phosphate 4-kinase type-2 beta2.7.1.1490.458
4b117I1Glycylpeptide N-tetradecanoyltransferase/0.458
4bfuZVUPantothenate kinase2.7.1.330.458
4dch4DCGlucokinase2.7.1.20.458
4ddl0JQcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.458
4gabFIDAldo-keto reductase family 1 member B101.1.10.458
4jva1ORcAMP-dependent protein kinase type II-beta regulatory subunit/0.458
4kbyC2EStimulator of interferon genes protein/0.458
4o78SAVBromodomain-containing protein 4/0.458
4tm0NAPKtzI/0.458
1fwmCB3Thymidylate synthase/0.457
1odjGMPPurine nucleoside phosphorylase/0.457
1ot7IU5Bile acid receptor/0.457
1pqc444Oxysterols receptor LXR-beta/0.457
1yciNDFHypoxia-inducible factor 1-alpha inhibitor1.14.11.300.457
1z6tADPApoptotic protease-activating factor 1/0.457
2ij7TPFMycocyclosin synthase1.14.21.90.457
2wnbC5PCMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 12.4.99.40.457
2zsbADPPantothenate kinase2.7.1.330.457
3djlFADPutative acyl-CoA dehydrogenase AidB1.3.990.457
3hxeBD8Geranylgeranyl transferase type-2 subunit beta2.5.1.600.457
3nwlNDPCatalase1.11.1.60.457
3qj0QI3Botulinum neurotoxin type A3.4.24.690.457
3uaxNOSPurine nucleoside phosphorylase DeoD-type/0.457
3ufl508Beta-secretase 13.4.23.460.457
3x025GPPhosphatidylinositol 5-phosphate 4-kinase type-2 beta2.7.1.1490.457
4a6eASEAcetylserotonin O-methyltransferase2.1.1.40.457
4do30LAFatty-acid amide hydrolase 13.5.1.990.457
4eufNADTrans-2-enoyl-CoA reductase [NADH]/0.457
4klaCHDFerrochelatase, mitochondrial4.99.1.10.457
4n3l2FNProthrombin3.4.21.50.457
4ure1PSCyclohexanol dehydrogenase/0.457
4zzi1NSNAD-dependent protein deacetylase sirtuin-13.5.10.457
5hwrCOAHydroxymethylglutaryl-CoA synthase/0.457
1fxoTMPGlucose-1-phosphate thymidylyltransferase/0.456
1h61PDNPentaerythritol tetranitrate reductase/0.456
1itzTPPTransketolase, chloroplastic2.2.1.10.456
1kt3RTLRetinol-binding protein 4/0.456
1t7o152Carnitine O-acetyltransferase2.3.1.70.456
1u1gBBBUridine phosphorylase2.4.2.30.456
1zgv501Prothrombin3.4.21.50.456
2a58RBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.456
2aazCB3Thymidylate synthase2.1.1.450.456
2bu9HFVIsopenicillin N synthase1.21.3.10.456
2ejzSAHDiphthine synthase/0.456
2f2sCOAAcetyl-CoA acetyltransferase, mitochondrial2.3.1.90.456
2g28TDKPyruvate dehydrogenase E1 component1.2.4.10.456
2pitDHTAndrogen receptor/0.456
2po7CHDFerrochelatase, mitochondrial4.99.1.10.456
2vtdLKMUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.456
2xk6EQHSerine/threonine-protein kinase Nek22.7.11.10.456
2xnvVU3Soluble acetylcholine receptor/0.456
3aiqHBO4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1b, chloroplastic3.2.1.1820.456
3atzFMNProstaglandin F2a synthase/0.456
3br3ETHTH-type transcriptional regulator QacR/0.456
3gjwGJWPoly [ADP-ribose] polymerase 12.4.2.300.456
3i8p8403-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.456
3nmpPYVAbscisic acid receptor PYL2/0.456
3pahXDEPhenylalanine-4-hydroxylase1.14.16.10.456
3x04GNPPhosphatidylinositol 5-phosphate 4-kinase type-2 beta2.7.1.1490.456
4ba5PXGProbable aminotransferase/0.456
4bj9UHBTankyrase-22.4.2.300.456
4c717RD3-oxoacyl-ACP synthase/0.456
4u9zCOAAlpha-tubulin N-acetyltransferase 1/0.456
4wdb2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.456
4wh2ADPN-acetylhexosamine 1-kinase2.7.1.1620.456
5d4vYGPUncharacterized protein MJ0489/0.456
5hbrCOAAcyl-CoA synthetase (NDP forming)/0.456
1h51FMNPentaerythritol tetranitrate reductase/0.455
1jtqLY3Thymidylate synthase/0.455
1kyvRBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.455
1kyxCRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.455
1mrqSTRAldo-keto reductase family 1 member C1/0.455
1oc1ASVIsopenicillin N synthase1.21.3.10.455
1q0zAKAAclacinomycin methylesterase RdmC3.1.1.950.455
1xl8152Peroxisomal carnitine O-octanoyltransferase2.3.1.1370.455
2bjsACVIsopenicillin N synthase1.21.3.10.455
2c2bSAMThreonine synthase 1, chloroplastic4.2.3.10.455
2fr0NDP6-deoxyerythronolide-B synthase EryA1, modules 1 and 2/0.455
2pncCLUPrimary amine oxidase, liver isozyme/0.455
3c15FOKAdenylate cyclase type 2/0.455
3c15FOKAdenylate cyclase type 5/0.455
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.455
3i1y33NBifunctional epoxide hydrolase 23.3.2.100.455
3ixp834Ecdysone receptor/0.455
4fhd0TTSpore photoproduct lyase/0.455
4j1k1HGBeta-secretase 13.4.23.460.455
4qe6JN3Bile acid receptor/0.455
4stdBFSScytalone dehydratase4.2.1.940.455
4twnB96Ephrin type-A receptor 32.7.10.10.455
1aiqCB3Thymidylate synthase/0.454
1dpmEBPParathion hydrolase3.1.8.10.454
1fdsESTEstradiol 17-beta-dehydrogenase 11.1.1.620.454
1h60STRPentaerythritol tetranitrate reductase/0.454
1ni12C5Protein farnesyltransferase subunit beta2.5.1.580.454
1swtBTNStreptavidin/0.454
1vbiNADMalate/L-lactate dehydrogenase family protein/0.454
1ygkRRCPyridoxal kinase2.7.1.350.454
2bktRPFRenin3.4.23.150.454
2c42TPPPyruvate synthase/0.454
2dw4FADLysine-specific histone demethylase 1A10.454
2f2kTGGAldose reductase1.1.1.210.454
2flhZEACytokinin-specific binding protein/0.454
2mokFMNFlavodoxin 1/0.454
2vbdV10Isopenicillin N synthase1.21.3.10.454
2w3mFOLDihydrofolate reductase1.5.1.30.454
2x86ADPADP-L-glycero-D-manno-heptose-6-epimerase/0.454
2xytTC9Soluble acetylcholine receptor/0.454
3bl7DD1m7GpppX diphosphatase3.6.1.590.454
3bxxQUEDihydroflavonol 4-reductase1.1.1.2190.454
3c3eFO12-phospho-L-lactate transferase/0.454
3cv9VDXVitamin D3 dihydroxylase/0.454
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.454
3gy9COAGCN5-related N-acetyltransferase/0.454
3jsiWTCHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.454
3mcvMCVPteridine reductase/0.454
3wv9FEGHmd co-occurring protein HcgE/0.454
3zbrNAP2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.454
4a81DXCMajor pollen allergen Bet v 1-A/0.454
4bmpFMNProtein NrdI/0.454
4c73TLH3-oxoacyl-ACP synthase/0.454
1cs4FOKAdenylate cyclase type 2/0.453
1cs4FOKAdenylate cyclase type 5/0.453
1fdwESTEstradiol 17-beta-dehydrogenase 11.1.1.620.453
1h22E10Acetylcholinesterase3.1.1.70.453
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.453
1q4wDQUQueuine tRNA-ribosyltransferase2.4.2.290.453
1z7yAA5Cysteine synthase 12.5.1.470.453
2a9y26AAdenosine kinase2.7.1.200.453
2ab2SNLMineralocorticoid receptor/0.453
2abaSTRPentaerythritol tetranitrate reductase/0.453
2hs8FMN12-oxophytodienoate reductase 31.3.1.420.453
2j9lATPH(+)/Cl(-) exchange transporter 5/0.453
2jb4A14Isopenicillin N synthase1.21.3.10.453
2nmtMIMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.453
2xi4AFTAcetylcholinesterase3.1.1.70.453
2xvhFADPutative flavin-containing monooxygenase/0.453
3b9xNOSPyrimidine-specific ribonucleoside hydrolase RihB3.2.2.80.453
3eksCY9Actin-5C/0.453
3gn73GNPoly [ADP-ribose] polymerase 12.4.2.300.453
3hy310F5-formyltetrahydrofolate cyclo-ligase6.3.3.20.453
3r8hZOMAldo-keto reductase family 1 member C3/0.453
3wznBTNStreptavidin/0.453
4a2zVIQGlycylpeptide N-tetradecanoyltransferase/0.453
4a33PS8Glycylpeptide N-tetradecanoyltransferase/0.453
4gtr7TRProtein farnesyltransferase subunit beta2.5.1.580.453
4k4eK4ETankyrase-12.4.2.300.453
4nh82LCHeat shock protein HSP 90-alpha/0.453
4ocvANPAminoglycoside phosphotransferase/0.453
5dozNDPJamJ/0.453
5hwpCOAHydroxymethylglutaryl-CoA synthase/0.453
2rh1CAUBeta-2 adrenergic receptor/0.453
1a9p9DIPurine nucleoside phosphorylase2.4.2.10.452
1dtpAPUDiphtheria toxin/0.452
1fmlRTLRetinol dehydratase/0.452
1ib0FADNADH-cytochrome b5 reductase 31.6.2.20.452
1kmsLIHDihydrofolate reductase1.5.1.30.452
1mraAPGMandelate racemase/0.452
1rfgGMPPurine nucleoside phosphorylase2.4.2.10.452
1txtCAAHMG-CoA synthase/0.452
1u1d181Uridine phosphorylase2.4.2.30.452
1ychFMNNitric oxide reductase10.452
2e9aB28Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.452
2fhlBNIAvidin-related protein 4/5/0.452
2in6839Wee1-like protein kinase2.7.10.20.452
2iodMYCDihydroflavonol 4-reductase1.1.1.2190.452
2rtgBTNStreptavidin/0.452
2w6oOA3Biotin carboxylase6.3.4.140.452
2w9hTOPDihydrofolate reductase1.5.1.30.452
2ydbNAP2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.452
2yoj8Y6Genome polyprotein2.7.7.480.452
2zevB71Geranylgeranyl pyrophosphate synthase/0.452
3bi6396Wee1-like protein kinase2.7.10.20.452
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.452
3ie3N11Glutathione S-transferase P2.5.1.180.452
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.452
3of3DIHPurine nucleoside phosphorylase DeoD-type 1/0.452
3qe2FMNNADPH--cytochrome P450 reductase/0.452
3tm5SFGUncharacterized protein/0.452
4b4w9L9Bifunctional protein FolD/0.452
4eb5PLPCysteine desulfurase IscS 2/0.452
5fltVJJCarbonic anhydrase 24.2.1.10.452
5il2SAHN6-adenosine-methyltransferase 70 kDa subunit/0.452
1akcPPEAspartate aminotransferase, mitochondrial2.6.1.10.451
1dr4HBIDihydrofolate reductase1.5.1.30.451
1gky5GPGuanylate kinase2.7.4.80.451
1jqdSAHHistamine N-methyltransferase2.1.1.80.451
1jutLYDThymidylate synthase/0.451
1n3sGTPGTP cyclohydrolase 13.5.4.160.451
2ab8MTPAdenosine kinase2.7.1.200.451
2c12FADNitroalkane oxidase1.7.3.10.451
2dsgSAHDiphthine synthase/0.451
2g1s4IGRenin3.4.23.150.451
2j3qTFLAcetylcholinesterase3.1.1.70.451
2jfz003Glutamate racemase/0.451
2oazI96Methionine aminopeptidase 2/0.451
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.451
2zb8IMNProstaglandin reductase 21.3.1.480.451
3dhaC6LN-acyl homoserine lactonase AiiA3.1.1.810.451
3h0bB35Beta-secretase 13.4.23.460.451
3htjETEbrA repressor/0.451
3nn6HNK6-hydroxy-L-nicotine oxidase/0.451
3owuEQUSteroid Delta-isomerase5.3.3.10.451
3q44D50M1 family aminopeptidase3.4.110.451
3ska053Genome polyprotein2.7.7.480.451
3stdMQ0Scytalone dehydratase4.2.1.940.451
4g8bHL6Alpha/beta hydrolase fold protein/0.451
4iilRBFMembrane lipoprotein TpN38(b)/0.451
4jlk1NODeoxycytidine kinase2.7.1.740.451
4k5o1OTM1 family aminopeptidase3.4.110.451
4nieNBHNuclear receptor ROR-gamma/0.451
5epeSAHUncharacterized protein/0.451
4amiG90Beta-1 adrenergic receptor/0.451
1g63FMNEpidermin decarboxylase4.1.10.450
1qyxASDEstradiol 17-beta-dehydrogenase 11.1.1.620.450
1u0wSTLChalcone synthase 22.3.1.740.450
1wuaAP8Actin, alpha skeletal muscle/0.450
2a0xDIHPurine nucleoside phosphorylase2.4.2.10.450
2bn4FADNADPH--cytochrome P450 reductase/0.450
2cleF6FTryptophan synthase alpha chain/0.450
2ga2A19Methionine aminopeptidase 2/0.450
2i65NADADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 13.2.2.60.450
2j5sKTAAlr4455 protein/0.450
2rd2QSIGlutamine--tRNA ligase6.1.1.180.450
3ewkFADSensory box histidine kinase/response regulator/0.450
3fhxPXLPyridoxal kinase2.7.1.350.450
3icpNADNAD-dependent epimerase/dehydratase/0.450
3nrrD16Bifunctional dihydrofolate reductase-thymidylate synthase/0.450
3vmmP0DAlanine--anticapsin ligase/0.450
4a83DXCMajor pollen allergen Bet v 1-A/0.450
4bfyZVYPantothenate kinase2.7.1.330.450
4du6GTPGTP cyclohydrolase 1/0.450
4eu4COASuccinyl-CoA:acetate CoA-transferase/0.450
4fflADPUncharacterized protein/0.450
4j3mAJ8Tankyrase-22.4.2.300.450
4lcw1VYMajor histocompatibility complex class I-related gene protein/0.450
4x28FDAAcyl-CoA dehydrogenase FadE26/0.450
4x28FDAAcyl-CoA dehydrogenase FadE27/0.450
5c6cCMPcGMP-dependent protein kinase 22.7.11.120.450
5k2aZMAAdenosine receptor A2a/0.450
1jdzFMBPurine nucleoside phosphorylase/0.449
1lv89PPPurine nucleoside phosphorylase2.4.2.10.449
1mzcBNEProtein farnesyltransferase subunit beta2.5.1.580.449
1ni1HFPProtein farnesyltransferase subunit beta2.5.1.580.449
1p91SAM23S rRNA (guanine(745)-N(1))-methyltransferase/0.449
1ppjANYCytochrome b/0.449
1pr1FMBPurine nucleoside phosphorylase DeoD-type/0.449
1q23FUAChloramphenicol acetyltransferase2.3.1.280.449
1qtqQSIGlutamine--tRNA ligase6.1.1.180.449
1trkTPPTransketolase 12.2.1.10.449
1xpqFADPolyamine oxidase FMS1/0.449
2cjfRP43-dehydroquinate dehydratase4.2.1.100.449
2huxSAHDiphthine synthase/0.449
2jfgUMAUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.449
2mm3CHOGastrotropin/0.449
2pdyFIDAldose reductase1.1.1.210.449
2uxoTACHTH-type transcriptional regulator TtgR/0.449
3aezGDPPantothenate kinase2.7.1.330.449
3aivHBO4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic3.2.1.1820.449
3em0CHDFatty acid-binding protein 6, ileal (gastrotropin)/0.449
3mauPLRPutative sphingosine-1-phosphate lyase/0.449
3v0n4GWHisto-blood group ABO system transferase/0.449
4d9eLCSD-cysteine desulfhydrase/0.449
4hwkSFYSepiapterin reductase1.1.1.1530.449
4iah1DXAlr2278 protein/0.449
4rrmA3TProbable threonine--tRNA ligase 26.1.1.30.449
4wctFADFructosyl amine:oxygen oxidoreductase/0.449
4zgsNADPutative D-lactate dehydrogenase/0.449
7catNDPCatalase1.11.1.60.449
1efyBZCPoly [ADP-ribose] polymerase 12.4.2.300.448
1nbmADPATP synthase subunit beta, mitochondrial3.6.3.140.448
1qzfCB3Bifunctional dihydrofolate reductase-thymidylate synthase/0.448
1rf7DHFDihydrofolate reductase1.5.1.30.448
1umcTDP2-oxoisovalerate dehydrogenase subunit alpha1.2.4.40.448
1umcTDP2-oxoisovalerate dehydrogenase subunit beta1.2.4.40.448
1x1aSAMC-20 methyltransferase/0.448
1y5xE89Queuine tRNA-ribosyltransferase2.4.2.290.448
1zz1SHHHistone deacetylase-like amidohydrolase3.5.10.448
2cy0NAPShikimate dehydrogenase (NADP(+))/0.448
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.448
2ycwCAUBeta-1 adrenergic receptor/0.448
3akm11DFatty acid-binding protein, intestinal/0.448
3exnACOProbable acetyltransferase/0.448
3fhxPLPPyridoxal kinase2.7.1.350.448
3gluLYS_VAL_METNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.448
3jpuTY4Transcriptional activator protein LasR/0.448
3n0hTOPDihydrofolate reductase1.5.1.30.448
3qge26FGenome polyprotein2.7.7.480.448
3vt8YI3Vitamin D3 receptor/0.448
3zhrTPPMultifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.448
4c2jCOA3-ketoacyl-CoA thiolase, mitochondrial2.3.1.160.448
4eb7PLPCysteine desulfurase IscS 2/0.448
4fk3325Serine/threonine-protein kinase B-raf2.7.11.10.448
4jtqNAPAldo-keto reductase family 1 member C2/0.448
4l7j1W2Beta-secretase 13.4.23.460.448
4n82FMNRibonucleotide reductase (NrdI family protein), putative/0.448
4ubuCOASteroid 3-ketoacyl-CoA thiolase/0.448
5gcnCOAHAT A1/0.448
3uonQNBMuscarinic acetylcholine receptor M2/0.448
1ay0TPPTransketolase 12.2.1.10.447
1gt5BZQOdorant-binding protein/0.447
1pr0NOSPurine nucleoside phosphorylase DeoD-type/0.447
1u1cBAUUridine phosphorylase2.4.2.30.447
1yw8A75Methionine aminopeptidase 2/0.447
2o6hINI6,7-dimethyl-8-ribityllumazine synthase 12.5.1.780.447
2ociTYCValacyclovir hydrolase3.10.447
2p9hIPTLactose operon repressor/0.447
2qboCAMCamphor 5-monooxygenase1.14.15.10.447
2qimZEAClass 10 plant pathogenesis-related protein/0.447
2rd678PPoly [ADP-ribose] polymerase 12.4.2.300.447
2vqbFADPutative flavin-containing monooxygenase/0.447
2xb9XNW3-dehydroquinate dehydratase4.2.1.100.447
3a25SAMtRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase/0.447
3arvSAUChitinase A/0.447
3c35KAIGlutamate receptor ionotropic, kainate 1/0.447
3eq02TSProthrombin3.4.21.50.447
3ho2N323-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.447
3junAKDPhenazine biosynthesis protein A/B/0.447
3o3jBB4Peptide deformylase 1B, chloroplastic/mitochondrial3.5.1.880.447
3oimVZ5Carbonic anhydrase 24.2.1.10.447
3t7vSAM3-methylornithine synthase/0.447
3uayADNPurine nucleoside phosphorylase DeoD-type/0.447
3vilSA0Beta-glucosidase/0.447
4a312CBGlycylpeptide N-tetradecanoyltransferase/0.447
4dz5NAPAldo-keto reductase family 1 member C3/0.447
4fqsLYAThymidylate synthase ThyA/0.447
4g47TZFMycocyclosin synthase1.14.21.90.447
4h6uACOAlpha-tubulin N-acetyltransferase 1/0.447
4j7uYTZSepiapterin reductase1.1.1.1530.447
4p53NAI2-epi-5-epi-valiolone synthase/0.447
4qa2SHHHistone deacetylase 83.5.1.980.447
4udaDEXMineralocorticoid receptor/0.447
5dcyNAPIridoid synthase1.3.1.990.447
7stdCRPScytalone dehydratase4.2.1.940.447
2ycxP32Beta-1 adrenergic receptor/0.447
1blzACVIsopenicillin N synthase1.21.3.10.446
1dr2TAPDihydrofolate reductase1.5.1.30.446
1k9sFM1Purine nucleoside phosphorylase DeoD-type/0.446
1kt7RTLRetinol-binding protein 4/0.446
1nasASESepiapterin reductase1.1.1.1530.446
1ot7CHCBile acid receptor/0.446
1pk92FAPurine nucleoside phosphorylase DeoD-type/0.446
1pkfEPDEpothilone C/D epoxidase1.140.446
1tduCB3Thymidylate synthase/0.446
1tw2ERTCarminomycin 4-O-methyltransferase DnrK2.1.1.2920.446
1zgbA1EAcetylcholinesterase3.1.1.70.446
2feuCAMCamphor 5-monooxygenase1.14.15.10.446
2fr1NDP6-deoxyerythronolide-B synthase EryA1, modules 1 and 2/0.446
2rteBTNStreptavidin/0.446
2v5aLZLBiotin carboxylase6.3.4.140.446
2xlsFADPutative flavin-containing monooxygenase/0.446
2z4sADPChromosomal replication initiator protein DnaA/0.446
3dhcCYKN-acyl homoserine lactonase AiiA3.1.1.810.446
3fr5I4AFatty acid-binding protein, adipocyte/0.446
3k4551PDihydrofolate reductase1.5.1.30.446
3ksqZ96Protein farnesyltransferase subunit beta2.5.1.580.446
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.446
3new3NEMitogen-activated protein kinase 14/0.446
3t82SG4Carbonic anhydrase 24.2.1.10.446
3t8vBTJM1 family aminopeptidase3.4.110.446
3v0o4GWHisto-blood group ABO system transferase/0.446
3zecANPAdenosine monophosphate-protein transferase SoFic2.7.7.n10.446
4a6rTA8Probable aminotransferase/0.446
4bfwZVWPantothenate kinase2.7.1.330.446
4dbuBT9Aldo-keto reductase family 1 member C3/0.446
4eilUMPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.446
4gdaBTNStreptavidin/0.446
4nv10FXFormyl transferase/0.446
4ryvZEAProtein LlR18A/0.446
4u0sADPAdenosine monophosphate-protein transferase FICD2.7.7.n10.446
4y1bNAPAntE/0.446
5bp9SAHPutative methyltransferase protein/0.446
5k2cZMAAdenosine receptor A2a/0.446
1cjvDADAdenylate cyclase type 2/0.445
1cjvDADAdenylate cyclase type 5/0.445
1dr5NAPDihydrofolate reductase1.5.1.30.445
1mvsDTMDihydrofolate reductase1.5.1.30.445
1nceCB3Thymidylate synthase/0.445
1pd9CO4Dihydrofolate reductase1.5.1.30.445
1qoqIGPTryptophan synthase alpha chain/0.445
1qrsATPGlutamine--tRNA ligase6.1.1.180.445
1qv1CZHObelin/0.445
1t4cCOAFormyl-CoA:oxalate CoA-transferase/0.445
1vyrFMNPentaerythritol tetranitrate reductase/0.445
1xmmM7Gm7GpppX diphosphatase3.6.1.590.445
1yvfPH7Polyprotein/0.445
2fxfACODiamine acetyltransferase 1/0.445
2v58LZJBiotin carboxylase6.3.4.140.445
2w6pOA4Biotin carboxylase6.3.4.140.445
2xkdT3MSerine/threonine-protein kinase Nek22.7.11.10.445
3cgtBCDCyclomaltodextrin glucanotransferase2.4.1.190.445
3ch6311Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.445
3dvaTPWPyruvate dehydrogenase E1 component subunit alpha1.2.4.10.445
3dvaTPWPyruvate dehydrogenase E1 component subunit beta1.2.4.10.445
3l63CAMCamphor 5-monooxygenase1.14.15.10.445
3n87N873-dehydroquinate dehydratase4.2.1.100.445
3sfi3SFHTH-type transcriptional regulator EthR/0.445
3uwlFOZThymidylate synthase/0.445
3vtdTKDVitamin D3 receptor/0.445
3x065GPPhosphatidylinositol 5-phosphate 4-kinase type-2 beta2.7.1.1490.445
3zksWZVBeta-secretase 23.4.23.450.445
4b63NAPL-ornithine N(5)-monooxygenase/0.445
4bprFADFerredoxin--NADP reductase1.18.1.20.445
4bqwQNMEgl nine homolog 1/0.445
4e2xTYDMethyltransferase/0.445
4f1yCNIGlutamate receptor 3/0.445
4jtrIBPAldo-keto reductase family 1 member C2/0.445
4l9q9TPSerum albumin/0.445
4n3r2GUTankyrase-12.4.2.300.445
4n4v2GYTankyrase-12.4.2.300.445
4rrdA3TProbable threonine--tRNA ligase 26.1.1.30.445
4xwtU5PRibonuclease J/0.445
5epoTUD7-alpha-hydroxysteroid deydrogenase/0.445
6ctsCICCitrate synthase, mitochondrial2.3.3.10.445
1d3pBT3Prothrombin3.4.21.50.444
1ef92CPMethylmalonyl-CoA decarboxylase4.1.1.410.444
1ex75GPGuanylate kinase2.7.4.80.444
1paxDHQPoly [ADP-ribose] polymerase 12.4.2.300.444
1sriDMBStreptavidin/0.444
1t2cNAIL-lactate dehydrogenase1.1.1.270.444
1u0hFOKAdenylate cyclase type 2/0.444
1u0hFOKAdenylate cyclase type 5/0.444
1ulbGUNPurine nucleoside phosphorylase2.4.2.10.444
1ykdCMPAdenylate cyclase/0.444
2a2dANPN-acetylgalactosamine kinase2.7.1.1570.444
2eklNADD-3-phosphoglycerate dehydrogenase/0.444
2geuCOKPantothenate kinase2.7.1.330.444
2qmzLDPRibosyldihydronicotinamide dehydrogenase [quinone]/0.444
2vb8TLM3-oxoacyl-[acyl-carrier-protein] synthase 12.3.1.410.444
2vq7FADPutative flavin-containing monooxygenase/0.444
2ywvADPPhosphoribosylaminoimidazole-succinocarboxamide synthase/0.444
2zrxFMNIsopentenyl-diphosphate delta-isomerase/0.444
3af1GDPPantothenate kinase2.7.1.330.444
3cotSTR3-oxo-5-beta-steroid 4-dehydrogenase/0.444
3dgeADPSensor histidine kinase/0.444
3g72A6TRenin3.4.23.150.444
3irhDTPHD domain protein/0.444
3n19FNRXenobiotic reductase/0.444
3ngq1PSCCR4-NOT transcription complex subunit 6-like3.1.13.40.444
3qftFADNADPH--cytochrome P450 reductase/0.444
3tfq07MCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.444
3w6hAZMCarbonic anhydrase 14.2.1.10.444
4b6r3DQ3-dehydroquinate dehydratase4.2.1.100.444
4b6s2HN3-dehydroquinate dehydratase4.2.1.100.444
4bgiI4IEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.444
4bqyFNTEgl nine homolog 1/0.444
4dldTZGGlutamate receptor ionotropic, kainate 1/0.444
4e2dFMNDehydrogenase/0.444
4ea2RWZDehydrosqualene synthase/0.444
4fc00T2Serine/threonine-protein kinase B-raf2.7.11.10.444
4h6kFMNNADPH dehydrogenase 11.6.99.10.444
4jq4IMNAldo-keto reductase family 1 member C2/0.444
4ktl1CQCytochrome P450/0.444
4l0qNADAlcohol dehydrogenase class-3/0.444
4lr61XABromodomain-containing protein 4/0.444
4lsaBLDProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.444
4lsjLSJGlucocorticoid receptor/0.444
4qij1HA1,4-dihydroxy-2-naphthoyl-CoA synthase/0.444
5bnw12VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.444
5fsi8DG7,8-dihydro-8-oxoguanine triphosphatase3.6.1.550.444
8catNDPCatalase1.11.1.60.444
4mqt2CUMuscarinic acetylcholine receptor M2/0.444
1gpeFADGlucose oxidase1.1.3.40.443
1kbo340NAD(P)H dehydrogenase [quinone] 11.6.5.20.443
1kkq471Peroxisome proliferator-activated receptor alpha/0.443
1stdBFSScytalone dehydratase4.2.1.940.443
1yryMSGPurine nucleoside phosphorylase2.4.2.10.443
2a2cADPN-acetylgalactosamine kinase2.7.1.1570.443
2abbFMNPentaerythritol tetranitrate reductase/0.443
2bf7HBIPteridine reductase 11.5.1.330.443
2ch2KY1Serine--pyruvate aminotransferase/0.443
2clhF19Tryptophan synthase alpha chain/0.443
2e8sSAHDiphthine synthase/0.443
2f6rACOBifunctional coenzyme A synthase/0.443
2iutAGSDNA translocase FtsK/0.443
2pixDHTAndrogen receptor/0.443
2pksG44Prothrombin3.4.21.50.443
2pl0STITyrosine-protein kinase Lck2.7.10.20.443
2rtoIMIStreptavidin/0.443
2trsPLSTryptophan synthase beta chain4.2.1.200.443
2vkeTACTetracycline repressor protein class D/0.443
3d84NDPDihydrofolate reductase1.5.1.30.443
3da24MDCarbonic anhydrase 134.2.1.10.443
3dufR1TPyruvate dehydrogenase E1 component subunit alpha1.2.4.10.443
3dufR1TPyruvate dehydrogenase E1 component subunit beta1.2.4.10.443
3epsATPIsocitrate dehydrogenase kinase/phosphatase/0.443
3hxcBD6Geranylgeranyl transferase type-2 subunit beta2.5.1.600.443
3i7vB4PAP4A hydrolase/0.443
3ju8NADN-succinylglutamate 5-semialdehyde dehydrogenase1.2.1.710.443
3jzfJZKBiotin carboxylase6.3.4.140.443
3lq2TDPPyruvate dehydrogenase E1 component1.2.4.10.443
3lxeTORCarbonic anhydrase 14.2.1.10.443
3ukfGDUUDP-galactopyranose mutase/0.443
4b68FADL-ornithine N(5)-monooxygenase/0.443
4e2bFMNDehydrogenase/0.443
4gi2NAPCrotonyl-CoA carboxylase/reductase/0.443
4gv4MEJPoly [ADP-ribose] polymerase 32.4.2.300.443
4ha6PXMPyridoxine 4-oxidase/0.443
4p9dTMPDeoxycytidylate deaminase/0.443
4relKMPGlycosyltransferase/0.443
4wdfA2P2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.443
4xt8TMQPossible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reduc/0.443
4zobLGCLin1840 protein/0.443
5cxv0HKMuscarinic acetylcholine receptor M1/0.443
1fduESTEstradiol 17-beta-dehydrogenase 11.1.1.620.442
1g3mPCQEstrogen sulfotransferase2.8.2.40.442
1icpFMN12-oxophytodienoate reductase 11.3.1.420.442
1jf0CZHObelin/0.442
1kw8BPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.442
1n5vNOMActVA 6 protein/0.442
1puaCOAHAT A1/0.442
1q6nP90Tyrosine-protein phosphatase non-receptor type 13.1.3.480.442
1qyw5SDEstradiol 17-beta-dehydrogenase 11.1.1.620.442
1ry0PG2Aldo-keto reductase family 1 member C3/0.442
1srjNABStreptavidin/0.442
1t7mDHTAndrogen receptor/0.442
2b03TUDPhospholipase A2, major isoenzyme3.1.1.40.442
2clfF6FTryptophan synthase alpha chain/0.442
2e0nSAHPrecorrin-2 C20-methyltransferase/0.442
2fa3ACOHydroxymethylglutaryl-CoA synthase/0.442
2g226IGRenin3.4.23.150.442
2j4qTTPdCTP deaminase/0.442
2ouyCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.442
2pdfZSTAldose reductase1.1.1.210.442
2r59PH0Leukotriene A-4 hydrolase3.3.2.60.442
2xuhTZ4Acetylcholinesterase3.1.1.70.442
2zhe13UProthrombin3.4.21.50.442
2zitNADExotoxin A2.4.2.360.442
3akn11DFatty acid-binding protein, intestinal/0.442
3b1dPLSBetaC-S lyase/0.442
3c1tMYCDihydroflavonol 4-reductase1.1.1.2190.442
3cavCI23-oxo-5-beta-steroid 4-dehydrogenase/0.442
3exhTPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.442
3exhTPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.442
3h3sH15Collagen type IV alpha-3-binding protein/0.442
3hkyIX6Genome polyprotein2.7.7.480.442
3hxfBD9Geranylgeranyl transferase type-2 subunit beta2.5.1.600.442
3jq8DX3Pteridine reductase, putative/0.442
3maaFKPAdenylate cyclase type 2/0.442
3maaFKPAdenylate cyclase type 5/0.442
3otwCOAPhosphopantetheine adenylyltransferase/0.442
3up0D7SaceDAF-12/0.442
4bbyFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.442
4bubADPUDP-N-acetylmuramoyl-L-alanyl-D-glutamate--LD-lysine ligase/0.442
4dro0MDPeptidyl-prolyl cis-trans isomerase FKBP55.2.1.80.442
4e960NSBromodomain-containing protein 4/0.442
4ef8FMNDihydroorotate dehydrogenase (fumarate)/0.442
4i13FOLDihydrofolate reductase1.5.1.30.442
4j8tDOGUncharacterized PhzA/B-like protein PA3332/0.442
4jeyPLPAcetylornithine/succinyldiaminopimelate aminotransferase2.6.1.110.442
4jt81NRNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.442
4jxxATPGlutamine--tRNA ligase6.1.1.180.442
4k36SAMAnaerobic sulfatase-maturating enzyme1.8.980.442
4mv1ADPBiotin carboxylase6.3.4.140.442
4rrfA3SThreonine--tRNA ligase6.1.1.30.442
4yp6NAPNicotinamide-nucleotide adenylyltransferase2.7.7.10.442
4zvnFADRibosyldihydronicotinamide dehydrogenase [quinone]/0.442
3qakUKAAdenosine receptor A2a/0.442
1e7aPFLSerum albumin/0.441
1g54FFBCarbonic anhydrase 24.2.1.10.441
1i05LTLMajor urinary protein 6/0.441
1jtuLYBThymidylate synthase/0.441
1kiaSAMGlycine N-methyltransferase2.1.1.200.441
1muuGDXGDP-mannose 6-dehydrogenase1.1.1.1320.441
1n95HFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.441
1n95HFPProtein farnesyltransferase subunit beta2.5.1.580.441
1opbRETRetinol-binding protein 2/0.441
1ps9MDE2,4-dienoyl-CoA reductase1.3.1.340.441
1rszDIHPurine nucleoside phosphorylase2.4.2.10.441
1swpBTQStreptavidin/0.441
1t76DHTAndrogen receptor/0.441
1x1cSAHC-20 methyltransferase/0.441
1y5rC0RCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.441
1z4uPH9Polyprotein/0.441
2a59LMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.441
2izlIMIStreptavidin/0.441
2j62GSZO-GlcNAcase NagJ/0.441
2o1sTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.441
2rtnIMIStreptavidin/0.441
2wn6NDPADP-ribosyltransferase enzymatic component/0.441
2wqpWQPPolysialic acid capsule biosynthesis protein SiaC/0.441
2x9gLYAPteridine reductase/0.441
2yg5FADPutrescine oxidase/0.441
2zgx29UProthrombin3.4.21.50.441
3bi5FADPolyamine oxidase FMS1/0.441
3csdEMOPutative ketoacyl reductase1.3.10.441
3e32ED2Protein farnesyltransferase subunit beta2.5.1.580.441
3fcoIIGCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.441
3fznD7KBenzoylformate decarboxylase4.1.1.70.441
3hl4CDCCholine-phosphate cytidylyltransferase A/0.441
3lz6A0DCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.441
3nmnPYVAbscisic acid receptor PYL1/0.441
3nubUD0UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase2.6.1.980.441
3occDIHPurine nucleoside phosphorylase DeoD-type/0.441
3to3ATPPetrobactin biosynthesis protein AsbB/0.441
3zkuHCVIsopenicillin N synthase1.21.3.10.441
3zr7OR8Progesterone receptor/0.441
4azwATPO-antigen chain terminator bifunctional methyltransferase/kinase WbdD/0.441
4br0AU1Ectonucleoside triphosphate diphosphohydrolase 2/0.441
4kebFOLDihydrofolate reductase1.5.1.30.441
4kuhCAA3-hydroxybutyryl-CoA dehydrogenase/0.441
4kw51W6Decaprenylphosphoryl-beta-D-ribose oxidase/0.441
4mryCEIObelin/0.441
4nbtNAD3-oxoacyl-[acyl-carrier-protein] reductase/0.441
4p5fAR6Inosine-uridine nucleoside N-ribohydrolase/0.441
3pblETQD(3) dopamine receptor/0.441
1b2lNDCAlcohol dehydrogenase1.1.1.10.440
1eiiRTLRetinol-binding protein 2/0.440
1sa4JANProtein farnesyltransferase subunit beta2.5.1.580.440
1sepBIOSepiapterin reductase1.1.1.1530.440
1swpBTNStreptavidin/0.440
1txzAPRProbable ADP-ribose 1''-phosphate phosphatase YML087W3.1.3.840.440
1xu7CPSCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.440
1y52BTNAvidin-related protein 4/5/0.440
1zq5E04Aldo-keto reductase family 1 member C3/0.440
2a57CRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.440
2g8yNADHydroxycarboxylate dehydrogenase B/0.440
2hkoFADLysine-specific histone demethylase 1A10.440
2o8jSAHHistone-lysine N-methyltransferase EHMT2/0.440
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.440
2uxhQUEHTH-type transcriptional regulator TtgR/0.440
2uz2BTNAvd protein/0.440
2xb8XNW3-dehydroquinate dehydratase4.2.1.100.440
2xvv9DNSerum albumin/0.440
2z2w770Wee1-like protein kinase2.7.10.20.440
2zrvFNRIsopentenyl-diphosphate delta-isomerase/0.440
3ed1GA3Gibberellin receptor GID1/0.440
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.440
3ha5SFGHydroxymycolate synthase MmaA42.1.10.440
3kkzSAMUncharacterized protein/0.440
3nhrRZWRibosyldihydronicotinamide dehydrogenase [quinone]/0.440
3q43D66M1 family aminopeptidase3.4.110.440
3rl45GPMetallophosphoesterase MPPED23.10.440
3s3vTOPDihydrofolate reductase1.5.1.30.440
3u5ySCGRaucaffricine-O-beta-D-glucosidase3.2.1.1250.440
3uyk0CXProbable NDP-rhamnosyltransferase/0.440
4bmoFMNProtein NrdI/0.440
4cf6CBDNAD(P)H dehydrogenase [quinone] 11.6.5.20.440
4cukNAID-lactate dehydrogenase/0.440
4hy6FJ1Heat shock protein HSP 90-alpha/0.440
4i6gFADCryptochrome-2/0.440
4i6h1C8Serine/threonine-protein kinase PLK22.7.11.210.440
4iszGAVtRNA-splicing ligase RtcB6.5.10.440
4kp61S1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.440
4ku5DCC3-oxoacyl-[ACP] synthase III/0.440
4rv9SAHD-mycarose 3-C-methyltransferase/0.440
5irnADPNucleotide binding oligomerization domain containing 2/0.440
5d5aCAUBeta-2 adrenergic receptor/0.440