sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2v9c | MRE | FMN-dependent NADH-azoreductase 1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2v9c | MRE | FMN-dependent NADH-azoreductase 1 | / | 1.000 | |
| 3keg | MRE | FMN-dependent NADH-azoreductase 1 | / | 0.500 | |
| 2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.499 | |
| 2xug | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.493 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.488 | |
| 1q83 | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.480 | |
| 2xuf | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.480 | |
| 2xuk | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.478 | |
| 1icq | OPD | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.477 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.475 | |
| 2xuh | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.475 | |
| 2xuj | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.471 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.466 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.463 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.462 | |
| 2gyw | OBI | Acetylcholinesterase | 3.1.1.7 | 0.458 | |
| 2xuq | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.457 | |
| 1c7o | PPG | Hemolysin | / | 0.456 | |
| 4ey7 | E20 | Acetylcholinesterase | 3.1.1.7 | 0.456 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.455 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 2ckm | AA7 | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 1zgc | A2E | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
| 2gyu | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 4b7z | Q4Q | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 4arb | C57 | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.444 | |
| 1ry0 | PG2 | Aldo-keto reductase family 1 member C3 | / | 0.441 | |
| 2aot | 2PM | Histamine N-methyltransferase | 2.1.1.8 | 0.441 | |
| 2jf0 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.440 |