Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2v6gNAP3-oxo-Delta(4,5)-steroid 5-beta-reductase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2v6gNAP3-oxo-Delta(4,5)-steroid 5-beta-reductase/1.000
5dcyNAPIridoid synthase1.3.1.990.565
5emhNAPIridoid synthase1.3.1.990.550
5dbgNADIridoid synthase1.3.1.990.544
5dbfNDPIridoid synthase1.3.1.990.537
4bmsNAPAlclohol dehydrogenase/short-chain dehydrogenase/0.460
1xkqNDPUncharacterized protein/0.459
1xg5NAPDehydrogenase/reductase SDR family member 11/0.446
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.445
1n5dNDPCarbonyl reductase [NADPH] 1/0.441