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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2v5vFMNFlavodoxin

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
2v5vFMNFlavodoxin/1.000
1fueFMNFlavodoxin/0.514
1yobFMNFlavodoxin 2/0.507
2x7hPFNProstaglandin reductase 310.507
1ia1NDPDihydrofolate reductase1.5.1.30.497
4a81DXCMajor pollen allergen Bet v 1-A/0.490
2c29NAPDihydroflavonol 4-reductase/0.488
3lpgZ78Beta-glucuronidase3.2.1.310.487
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.486
4djaFAD(6-4) photolyase/0.486
3esyFMNFlavodoxin/0.483
1cbqRE9Cellular retinoic acid-binding protein 2/0.482
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.482
2g1o2IGRenin3.4.23.150.482
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.480
1tj0FADBifunctional protein PutA1.5.5.20.479
1ykgFMNSulfite reductase [NADPH] flavoprotein alpha-component/0.479
3gbuATPUncharacterized sugar kinase PH14592.7.10.478
4bb3KKAIsopenicillin N synthase1.21.3.10.478
4jq7KJQEpidermal growth factor receptor2.7.10.10.478
3gdpFAD(R)-mandelonitrile lyase 24.1.2.100.477
1cznFMNFlavodoxin/0.475
2rc6NAPFerredoxin--NADP reductase/0.475
1bp6UMPThymidylate synthase/0.474
2pr2DG1Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.474
3em0CHDFatty acid-binding protein 6, ileal (gastrotropin)/0.474
3il1B5DGlutamate receptor 2/0.474
1l4gNCNNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase2.4.2.210.473
2qn7HBZGlycogen phosphorylase, muscle form2.4.1.10.473
3mt817TGlycogen phosphorylase, muscle form2.4.1.10.473
3oqkS52Renin3.4.23.150.473
4a802ANMajor pollen allergen Bet v 1-A/0.473
4ek1CAMCamphor 5-monooxygenase1.14.15.10.473
4el0D1KGlycogen phosphorylase, muscle form2.4.1.10.473
3qfrNAPNADPH--cytochrome P450 reductase/0.472
1oc1ASVIsopenicillin N synthase1.21.3.10.471
1pq944BOxysterols receptor LXR-beta/0.471
3gyuDL7Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.471
4ku5DCC3-oxoacyl-[ACP] synthase III/0.470
1u7tNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.469
1m78NDPDihydrofolate reductase1.5.1.30.468
1ofvFMNFlavodoxin/0.468
3toxNAPPutative oxidoreductase/0.468
3vri1KXHLA class I histocompatibility antigen, B-57 alpha chain/0.468
4rqzVAL_TYR_GLN_PHESerine endoprotease DegS3.4.21.1070.468
4u8iFDAUDP-galactopyranose mutase/0.468
4xwzFADFructosyl amine:oxygen oxidoreductase/0.468
1g0rTHMGlucose-1-phosphate thymidylyltransferase/0.467
2jcvNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.467
3o03NAPDehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase)/0.467
1njaDCMThymidylate synthase/0.466
2bfqAR6[Protein ADP-ribosylglutamate] hydrolase AF_15213.2.20.466
2ddoATPPyridoxine/pyridoxal/pyridoxamine kinase/0.466
4h8aNAIUreidoglycolate dehydrogenase (NAD(+))1.1.1.3500.466
1l2oADPMyosin heavy chain, striated muscle/0.465
2hpvFMNFMN-dependent NADH-azoreductase1.70.465
2r6gATPMaltose/maltodextrin import ATP-binding protein MalK/0.465
2vprTDCTetracycline repressor protein class H/0.465
2w5uFMNFlavodoxin/0.465
2w6oOA3Biotin carboxylase6.3.4.140.465
3kb1ADPIron-sulfur cluster carrier protein/0.465
3r5yF42Uncharacterized protein/0.465
1r2jFADFkbI/0.464
1u0hONMAdenylate cyclase type 2/0.464
1u0hONMAdenylate cyclase type 5/0.464
2ahrNAPPyrroline-5-carboxylate reductase/0.464
2aq8NAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.464
2xgoZKDUncharacterized protein/0.464
3mykANPMyosin-2 heavy chain/0.464
4itfTFYVitamin D3 receptor/0.464
4kp71UQ1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic1.1.1.2670.464
4m9aFDAAcyl-CoA dehydrogenase/0.464
1xduSFGAclacinomycin 10-hydroxylase RdmB4.1.10.463
2e07SAHDiphthine synthase/0.463
2v59LZKBiotin carboxylase6.3.4.140.463
3aosJH2Hemolymph juvenile hormone binding protein/0.463
3gwfFADCyclohexanone monooxygenase/0.463
3qlrNDPDihydrofolate reductase1.5.1.30.463
4at0FADPossible succinate dehydrogenase/0.463
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.463
5jlaNADPutative short-chain dehydrogenase/reductase/0.463
1ie8KH1Vitamin D3 receptor/0.462
1t57FMNConserved protein/0.462
2bifANP6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 42.7.1.1050.462
2zrvFNRIsopentenyl-diphosphate delta-isomerase/0.462
3adaNADSubunit alpha of sarocosine oxidase/0.462
3bwcSAMSpermidine synthase, putative/0.462
3jv7NADSecondary alcohol dehydrogenase/0.462
1kc1NDPdTDP-4-dehydrorhamnose reductase1.1.1.1330.461
1o8cNDPProbable acrylyl-CoA reductase AcuI1.3.1.840.461
2jb4A14Isopenicillin N synthase1.21.3.10.461
3idsNADGlyceraldehyde-3-phosphate dehydrogenase, glycosomal1.2.1.120.461
4ure1PSCyclohexanol dehydrogenase/0.461
5dp2NAPCurF/0.461
1tehNADAlcohol dehydrogenase class-31.1.1.10.460
1tj1FADBifunctional protein PutA1.5.5.20.460
2a92NAIL-lactate dehydrogenase/0.460
3uzwNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.460
5eccNAPDehydrofolate reductase type I/0.460
1fxsNAPGDP-L-fucose synthase/0.459
3bg7FADPyranose 2-oxidase/0.459
3dv3MEKDual specificity mitogen-activated protein kinase kinase 12.7.12.20.459
3qfrFMNNADPH--cytochrome P450 reductase/0.459
4dreNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.459
4dymIYZActivin receptor type-12.7.11.300.459
4h2dFMNNADPH-dependent diflavin oxidoreductase 1/0.459
4yerADPAntibiotic ABC transporter, ATP-binding protein, putative/0.459
3sn6P0GBeta-2 adrenergic receptor/0.459
1n83CLRNuclear receptor ROR-alpha/0.458
2ed3SAHDiphthine synthase/0.458
2fznFADBifunctional protein PutA1.5.5.20.458
3nx4NAPPutative oxidoreductase/0.458
3vdqNAD3-hydroxybutyrate dehydrogenase/0.458
4ekeD1IGlycogen phosphorylase, muscle form2.4.1.10.458
4q0kGA3Phytohormone-binding protein/0.458
1kqmANPMyosin heavy chain, striated muscle/0.457
1rx1NAPDihydrofolate reductase1.5.1.30.457
1vzaUMPThymidylate synthase/0.457
2a1hGBNBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.457
2b35TCLEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.457
2b4rNADGlyceraldehyde-3-phosphate dehydrogenase/0.457
2cibCM6Lanosterol 14-alpha demethylase1.14.13.700.457
2qn3F55Glycogen phosphorylase, muscle form2.4.1.10.457
3amfFMNFMN-binding protein/0.457
3ms421NGlycogen phosphorylase, muscle form2.4.1.10.457
1kfbIGPTryptophan synthase alpha chain/0.456
1kr2TADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.456
1njbUMPThymidylate synthase/0.456
1svlADPLarge T antigen3.6.40.456
1tj2FADBifunctional protein PutA1.5.5.20.456
2pk3A2RGDP-6-deoxy-D-mannose reductase/0.456
2v13C40Renin3.4.23.150.456
2w6pOA4Biotin carboxylase6.3.4.140.456
2zz0FADThioredoxin reductase 1, cytoplasmic1.8.1.90.456
4a862ANMajor pollen allergen Bet v 1-A/0.456
4c59FEFCyclin-G-associated kinase2.7.11.10.456
4jnkZHKL-lactate dehydrogenase A chain1.1.1.270.456
4rrxLURProstaglandin G/H synthase 21.14.99.10.456
4tuvCPZCytochrome P450 1191.140.456
1blzACVIsopenicillin N synthase1.21.3.10.455
1xl5190Gag-Pol polyprotein3.4.23.160.455
2cftPLPPyridoxal phosphate phosphatase/0.455
2nnlNAPDihydroflavonol 4-reductase1.1.1.2190.455
2vn0TDZCytochrome P450 2C8/0.455
2z7hGG3Geranylgeranyl pyrophosphate synthase/0.455
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.455
4fw8NAI3-oxoacyl-(Acyl-carrier-protein) reductase/0.455
4im01FVSerine/threonine-protein kinase TBK12.7.11.10.455
1e6wNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.454
1fdsESTEstradiol 17-beta-dehydrogenase 11.1.1.620.454
1g63FMNEpidermin decarboxylase4.1.10.454
1p4aPCPPur operon repressor/0.454
1t2cNAIL-lactate dehydrogenase1.1.1.270.454
1w6hTITPlasmepsin-23.4.23.390.454
2o23NAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.454
2xlpFADPutative flavin-containing monooxygenase/0.454
2z52H23Geranylgeranyl pyrophosphate synthase/0.454
3ab1FADFerredoxin--NADP reductase1.18.1.20.454
3p97SAMGenome polyprotein2.1.1.560.454
4b67NAPL-ornithine N(5)-monooxygenase/0.454
4bcrWY1Peroxisome proliferator-activated receptor alpha/0.454
4dpdDHFBifunctional dihydrofolate reductase-thymidylate synthase/0.454
4nd4NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.454
4otyLURProstaglandin G/H synthase 21.14.99.10.454
4xg1LLPDiaminopimelate decarboxylase/0.454
5eaiFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.454
5kjcNAJAlcohol dehydrogenase E chain1.1.1.10.454
1bv9XV6Gag-Pol polyprotein3.4.23.160.453
1nooCAHCamphor 5-monooxygenase1.14.15.10.453
1o76CAMCamphor 5-monooxygenase1.14.15.10.453
1v35NAIEnoyl-ACP reductase/0.453
1z7yAA5Cysteine synthase 12.5.1.470.453
2gmhFADElectron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial1.5.5.10.453
2p20PRXAcetyl-coenzyme A synthetase/0.453
3bgxMEFThymidylate synthase/0.453
3clsFADElectron transfer flavoprotein subunit alpha/0.453
3cz7ACOHistone acetyltransferase RTT1092.3.1.480.453
3p3zP3ZPutative cytochrome P450/0.453
3wb2YGPUncharacterized protein MJ0488/0.453
4ck2NVUIntegrase/0.453
4enhFVXCholesterol 24-hydroxylase/0.453
4qxmNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.453
4x9nFADUncharacterized protein MG039 homolog/0.453
1equEQIEstradiol 17-beta-dehydrogenase 11.1.1.620.452
1ib0FADNADH-cytochrome b5 reductase 31.6.2.20.452
1rw8580TGF-beta receptor type-12.7.11.300.452
2c20NADUDP-glucose 4-epimerase/0.452
2ed4FAD4-hydroxyphenylacetate 3-monooxygenase reductase component1.5.1.360.452
2fcrFMNFlavodoxin/0.452
2ggsNDPdTDP-4-dehydrorhamnose reductase/0.452
2givACOHistone acetyltransferase KAT8/0.452
2j14GNIPeroxisome proliferator-activated receptor delta/0.452
2q7vFADThioredoxin reductase/0.452
2uxpCLMHTH-type transcriptional regulator TtgR/0.452
3c35KAIGlutamate receptor ionotropic, kainate 1/0.452
3gwnFADProbable FAD-linked sulfhydryl oxidase R5961.8.3.20.452
3jziJZLBiotin carboxylase6.3.4.140.452
3koyZ97D-ornithine 4,5-aminomutase subunit beta/0.452
3q33ACOHistone acetyltransferase RTT1092.3.1.480.452
3uptTPPTransketolase/0.452
3vjoANPEpidermal growth factor receptor2.7.10.10.452
4ge40KEKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.452
4iqgNAPShort-chain dehydrogenase/reductase SDR/0.452
6adhNADAlcohol dehydrogenase E chain1.1.1.10.452
1lbcCYZGlutamate receptor 2/0.451
1obnASVIsopenicillin N synthase1.21.3.10.451
1upw444Oxysterols receptor LXR-beta/0.451
2c31TZDOxalyl-CoA decarboxylase4.1.1.80.451
2g8yNADHydroxycarboxylate dehydrogenase B/0.451
2p2bPRXAcetyl-coenzyme A synthetase/0.451
2qlnF59Glycogen phosphorylase, muscle form2.4.1.10.451
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.451
3f3sNADLambda-crystallin homolog/0.451
3qwpSAMHistone-lysine N-methyltransferase SMYD32.1.1.430.451
4n6hEJ4Delta-type opioid receptor/0.451
4oztP1AEcdysone receptor, putative/0.451
4riyADPEpidermal growth factor receptor2.7.10.10.451
4yaiNAIC alpha-dehydrogenase/0.451
5kgjACOPredicted acetyltransferase/0.451
1dirNADDihydropteridine reductase1.5.1.340.450
1jmiUMPThymidylate synthase/0.450
1nzfUPGDNA beta-glucosyltransferase/0.450
1p0pBCHCholinesterase3.1.1.80.450
1phgMYTCamphor 5-monooxygenase1.14.15.10.450
2ejzSAHDiphthine synthase/0.450
2iodMYCDihydroflavonol 4-reductase1.1.1.2190.450
2qs3UBEGlutamate receptor ionotropic, kainate 1/0.450
2uuvFADAlkyldihydroxyacetonephosphate synthase2.5.1.260.450
2vkeTACTetracycline repressor protein class D/0.450
3qlsNDPDihydrofolate reductase1.5.1.30.450
4cjeQ31Integrase/0.450
4eb7PLPCysteine desulfurase IscS 2/0.450
4emtC2EStimulator of interferon genes protein/0.450
4fm5DF0Prostaglandin G/H synthase 21.14.99.10.450
4i6aHMG3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.880.450
4l4xNDPAmphI/0.450
4m6jNDPDihydrofolate reductase1.5.1.30.450
5ifiPRXAcetyl-coenzyme A synthetase/0.450
1jmgUMPThymidylate synthase/0.449
1mjbACOHistone acetyltransferase ESA1/0.449
1nq5NADGlyceraldehyde-3-phosphate dehydrogenase/0.449
2b35NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.449
2q2qNADBeta-D-hydroxybutyrate dehydrogenase/0.449
2xhd7T9Glutamate receptor 2/0.449
2y0mACOHistone acetyltransferase KAT8/0.449
2zatNAPDehydrogenase/reductase SDR family member 41.1.1.1840.449
3iltTRUGlutamate receptor 2/0.449
3otfCMPPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4/0.449
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
4dc0NDPPutative ketoacyl reductase1.3.10.449
4hi0GDPUrease accessory protein UreG/0.449
4nd2A3DLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.449
4yp7NAPNicotinamide-nucleotide adenylyltransferase2.7.7.10.449
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.449
5c8wPCGcGMP-dependent protein kinase 22.7.11.120.449
5f8eSAHPossible transcriptional regulatory protein/0.449
1dgmADNAdenosine kinase2.7.1.200.448
1e3eNAIAlcohol dehydrogenase 41.1.1.10.448
1hb3SCVIsopenicillin N synthase1.21.3.10.448
1vcfFMNIsopentenyl-diphosphate delta-isomerase/0.448
2xw7NDPDihydrofolate reductase/0.448
3b05FNRIsopentenyl-diphosphate delta-isomerase/0.448
3bv7NAP3-oxo-5-beta-steroid 4-dehydrogenase/0.448
3dyqIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.448
3qfsNAPNADPH--cytochrome P450 reductase/0.448
3vi7CBDHematopoietic prostaglandin D synthase/0.448
4a83DXCMajor pollen allergen Bet v 1-A/0.448
4egbNADdTDP-glucose 4,6-dehydratase/0.448
4qvtACOAcetyltransferase YpeA2.3.10.448
4s1iPLPPyridoxal kinase, putative/0.448
4uymVOR14-alpha sterol demethylase Cyp51B/0.448
4wsoNADProbable nicotinate-nucleotide adenylyltransferase/0.448
5hbrCOAAcyl-CoA synthetase (NDP forming)/0.448
1iqrFADDeoxyribodipyrimidine photo-lyase4.1.99.30.447
2ek7SAHDiphthine synthase/0.447
2g9rG27Glycogen phosphorylase, muscle form2.4.1.10.447
2pchSAHDiphthine synthase/0.447
3e8xNAPBH1520 protein/0.447
3i1y33NBifunctional epoxide hydrolase 23.3.2.100.447
3ijoB4DGlutamate receptor 2/0.447
3vucHHERenin3.4.23.150.447
3w2fNADNADH-cytochrome b5 reductase 31.6.2.20.447
4b722FBBeta-secretase 13.4.23.460.447
4c3xFAD3-ketosteroid dehydrogenase/0.447
4cfaWOPIntegrase/0.447
4fgrADPPhosphoribosylaminoimidazole-succinocarboxamide synthase6.3.2.60.447
4kxn6K62'-deoxynucleoside 5'-phosphate N-hydrolase 1/0.447
4p9dTMPDeoxycytidylate deaminase/0.447
4ph9IBPProstaglandin G/H synthase 21.14.99.10.447
4u9yCOAAlpha-tubulin N-acetyltransferase 1/0.447
5c1mCLRMu-type opioid receptor/0.447
1dbvNADGlyceraldehyde-3-phosphate dehydrogenase/0.446
1g4tFTPThiamine-phosphate synthase/0.446
1n2sNAIdTDP-4-dehydrorhamnose reductase1.1.1.1330.446
1ndhFADNADH-cytochrome b5 reductase 31.6.2.20.446
1qorNDPQuinone oxidoreductase 1/0.446
2egsSAHDiphthine synthase/0.446
2w9sTOPDihydrofolate reductase type 1 from Tn40031.5.1.30.446
2x9dITCTetracycline repressor protein class D/0.446
3iaaTYDCalG2/0.446
3lq4TDPPyruvate dehydrogenase E1 component1.2.4.10.446
3pm1ETHTH-type transcriptional regulator QacR/0.446
3rtnRTNBeta-secretase 13.4.23.460.446
3uyk0CXProbable NDP-rhamnosyltransferase/0.446
3w0c6DSVitamin D3 receptor/0.446
3x2fNAIAdenosylhomocysteinase/0.446
4bmoFMNProtein NrdI/0.446
4bmpFMNProtein NrdI/0.446
4c43FADFerredoxin--NADP reductase1.18.1.20.446
4eakATP5'-AMP-activated protein kinase subunit gamma-1/0.446
4ftcH6KSerine/threonine-protein kinase Chk12.7.11.10.446
4hp8NAP2-deoxy-D-gluconate 3-dehydrogenase/0.446
4jq8KJ8Epidermal growth factor receptor2.7.10.10.446
4jr3KJREpidermal growth factor receptor2.7.10.10.446
4q72FADBifunctional protein PutA/0.446
5j60FADThioredoxin reductase/0.446
5k0s0OUMethionine--tRNA ligase/0.446
1bk0ACVIsopenicillin N synthase1.21.3.10.445
1fndA2PFerredoxin--NADP reductase, chloroplastic1.18.1.20.445
1ihxSNDGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.445
1kzjCB3Thymidylate synthase/0.445
1vceSAHDiphthine synthase/0.445
1xddAAYIntegrin alpha-L/0.445
2abbFMNPentaerythritol tetranitrate reductase/0.445
2o7pNAPRiboflavin biosynthesis protein RibD/0.445
2v58LZJBiotin carboxylase6.3.4.140.445
3dmhSAMProbable ribosomal RNA small subunit methyltransferase/0.445
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.445
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.445
4coxIMNProstaglandin G/H synthase 21.14.99.10.445
4dfg0JVGag-Pol polyprotein3.4.23.160.445
4jv81M1Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.445
4q71FADBifunctional protein PutA/0.445
4yaoFMNNADPH--cytochrome P450 reductase/0.445
5dqrFAD7-hydroxymethyl chlorophyll a reductase, chloroplastic1.17.7.20.445
5il2SAHN6-adenosine-methyltransferase 70 kDa subunit/0.445
5jjsSAHGenome polyprotein/0.445
1bduDURThymidylate synthase/0.444
1cf2NAPGlyceraldehyde-3-phosphate dehydrogenase/0.444
1drhNAPDihydrofolate reductase1.5.1.30.444
1ezvUQ6Cytochrome b/0.444
1fduNAPEstradiol 17-beta-dehydrogenase 11.1.1.620.444
1jg0DDTThymidylate synthase/0.444
1jmhUMPThymidylate synthase/0.444
1qvuPRLHTH-type transcriptional regulator QacR/0.444
1r00SAHAclacinomycin 10-hydroxylase RdmB4.1.10.444
1thyUMPThymidylate synthase/0.444
1tqf32PBeta-secretase 13.4.23.460.444
1u33LM2Pancreatic alpha-amylase/0.444
1zemNADXylitol dehydrogenase/0.444
2am22LGUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase/0.444
2bslFMNDihydroorotate dehydrogenase A (fumarate)1.3.98.10.444
2c27ACOMycothiol acetyltransferase2.3.1.1890.444
2gvdFKPAdenylate cyclase type 2/0.444
2gvdFKPAdenylate cyclase type 5/0.444
2ien017Gag-Pol polyprotein3.4.23.160.444
2itpAEEEpidermal growth factor receptor2.7.10.10.444
2j08IRFDeoxyribodipyrimidine photo-lyase4.1.99.30.444
2j5xGSPADP-ribosylation factor 6/0.444
2nr4FMNConserved protein/0.444
2p5uNADUDP-glucose 4-epimerase/0.444
2rc4ACOHistone acetyltransferase KAT6A/0.444
2rehFADNitroalkane oxidase1.7.3.10.444
2xlrFADPutative flavin-containing monooxygenase/0.444
3bnkFMNFlavoredoxin/0.444
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.444
3ha7B32Hydroxymycolate synthase MmaA42.1.10.444
3jynNDPQuinone oxidoreductase/0.444
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.444
3kjrNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.444
3mtfA3FActivin receptor type-12.7.11.300.444
3oq6NAJAlcohol dehydrogenase E chain1.1.1.10.444
3u9eCOALmo1369 protein/0.444
3uicNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.444
3zcsCAWGlycogen phosphorylase, muscle form2.4.1.10.444
4ceqQCHIntegrase/0.444
4jtqNAPAldo-keto reductase family 1 member C2/0.444
4kwhNAPReductase homolog/0.444
4xd2NAIAlcohol dehydrogenase E chain1.1.1.10.444
5cdgNAJAlcohol dehydrogenase E chain1.1.1.10.444
1ahnFMNFlavodoxin 1/0.443
1ie9VDXVitamin D3 receptor/0.443
1lf3EH5Plasmepsin-23.4.23.390.443
1pjcNADAlanine dehydrogenase/0.443
1q12ATPMaltose/maltodextrin import ATP-binding protein MalK/0.443
1txtCAAHMG-CoA synthase/0.443
2bxmIMNSerum albumin/0.443
2ktdPUCProstaglandin-H2 D-isomerase5.3.99.20.443
2q2vNADBeta-D-hydroxybutyrate dehydrogenase/0.443
2wnsOMPUridine 5'-monophosphate synthase2.4.2.100.443
2xk85R1Serine/threonine-protein kinase Nek22.7.11.10.443
3cgdCOACoenzyme A disulfide reductase/0.443
3eluSAMMethyltransferase/0.443
3fp0FP015-O-acetyltransferase/0.443
3fql79ZGenome polyprotein2.7.7.480.443
3o4rNAPDehydrogenase/reductase SDR family member 41.1.1.1840.443
3ojxFMNNADPH--cytochrome P450 reductase/0.443
3p62FMNPentaerythritol tetranitrate reductase/0.443
3tpr5HABeta-secretase 13.4.23.460.443
3up0D7SaceDAF-12/0.443
3vo2FADFerredoxin--NADP reductase/0.443
3vtdTKDVitamin D3 receptor/0.443
4biiPYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.443
4cjp4D2Integrase/0.443
4i02CMPcAMP-activated global transcriptional regulator CRP/0.443
4jlj1NMDeoxycytidine kinase2.7.1.740.443
4l1xNAPAldo-keto reductase family 1 member C2/0.443
4n82FMNRibonucleotide reductase (NrdI family protein), putative/0.443
4nwiCTN7-methylguanosine phosphate-specific 5'-nucleotidase/0.443
4o7uTHFThymidylate synthase/0.443
4trnNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.443
5e8jSAHmRNA cap guanine-N7 methyltransferase2.1.1.560.443
5fx2FMNFlavodoxin/0.443
1ja0FMNNADPH--cytochrome P450 reductase/0.442
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.442
1ot7CHCBile acid receptor/0.442
1qk35GPHypoxanthine-guanine-xanthine phosphoribosyltransferase2.4.2.220.442
2acxANPG protein-coupled receptor kinase 62.7.11.160.442
2bpoNAPNADPH--cytochrome P450 reductase/0.442
2hcdBIVVitamin D3 receptor A/0.442
2nu9COASuccinate--CoA ligase [ADP-forming] subunit alpha6.2.1.50.442
2ylsFADPhenylacetone monooxygenase1.14.13.920.442
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.442
3ekuCY9Actin-5C/0.442
3nxxNDPDihydrofolate reductase1.5.1.30.442
3pce3HPProtocatechuate 3,4-dioxygenase alpha chain1.13.11.30.442
3pce3HPProtocatechuate 3,4-dioxygenase beta chain1.13.11.30.442
3pdnSFGHistone-lysine N-methyltransferase SMYD32.1.1.430.442
3qrwNDPPutative ketoacyl reductase1.3.10.442
3ruhNADUDP-N-acetylglucosamine 4-epimerase/0.442
3w78CBDFMN-dependent NADH-azoreductase/0.442
3wv7ADPHmd co-occurring protein HcgE/0.442
3zc3NAPFerredoxin--NADP reductase1.18.1.20.442
4cdmFADDeoxyribodipyrimidine photolyase/0.442
4fhbFOLDihydrofolate reductase1.5.1.30.442
4frkDWDBeta-secretase 13.4.23.460.442
4jwfSAHtRNA (guanine(9)-N1)-methyltransferase/0.442
4lx9ACON-alpha-acetyltransferase2.3.10.442
4nbtNAD3-oxoacyl-[acyl-carrier-protein] reductase/0.442
4xx0COASuccinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial6.2.1.40.442
4yfy1YJVioF/0.442
5b0oADPFlagellum-specific ATP synthase3.6.3.140.442
5cpbNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
5hq8SAHHistone-lysine N-methyltransferase SMYD32.1.1.430.442
6coxS58Prostaglandin G/H synthase 21.14.99.10.442
1bpjUMPThymidylate synthase/0.441
1ci7UMPThymidylate synthase2.1.1.450.441
1hk4T44Serum albumin/0.441
1uzwCDHIsopenicillin N synthase1.21.3.10.441
2c2aADPSensor histidine kinase/0.441
2d1yNADOxidoreductase, short-chain dehydrogenase/reductase family/0.441
2dv4SAHDiphthine synthase/0.441
2i0zFADNAD(FAD)-utilizing dehydrogenases/0.441
2uzuL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.441
2wa2SAMGenome polyprotein/0.441
2y60M8FIsopenicillin N synthase1.21.3.10.441
3ajrNADNDP-sugar epimerase/0.441
3atyFMNProstaglandin F2a synthase/0.441
3f6rFMNFlavodoxin/0.441
3fu83DMLaccase-11.10.3.20.441
3l7dDK5Glycogen phosphorylase, muscle form2.4.1.10.441
3ntgD72Prostaglandin G/H synthase 21.14.99.10.441
3pndFADFAD:protein FMN transferase/0.441
3zk5Z18Cytochrome P450 monooxygenase PikC/0.441
4c02TAKActivin receptor type-12.7.11.300.441
4cjfRVNIntegrase/0.441
4cjqVXOIntegrase/0.441
4hy6FJ1Heat shock protein HSP 90-alpha/0.441
4jlm1NNDeoxycytidine kinase2.7.1.740.441
4l4dCAMCamphor 5-monooxygenase1.14.15.10.441
4twnB96Ephrin type-A receptor 32.7.10.10.441
4z3dNDPCarbonyl reductase [NADPH] 11.1.1.1840.441
1cbsREACellular retinoic acid-binding protein 2/0.440
1dr3TAPDihydrofolate reductase1.5.1.30.440
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.440
1h62ANBPentaerythritol tetranitrate reductase/0.440
1itzTPPTransketolase, chloroplastic2.2.1.10.440
1lwiNAP3-alpha-hydroxysteroid dehydrogenase1.1.1.500.440
1me6IVSPlasmepsin-23.4.23.390.440
1ozhHE3Acetolactate synthase, catabolic2.2.1.60.440
1x1cSAHC-20 methyltransferase/0.440
2b9wFADPutative aminooxidase/0.440
2eeqSAHDiphthine synthase/0.440
2g1s4IGRenin3.4.23.150.440
2i4pDRHPeroxisome proliferator-activated receptor gamma/0.440
2o1sTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.440
2p5fSAHDiphthine synthase/0.440
2pa3NAID-3-phosphoglycerate dehydrogenase1.1.1.950.440
2q9fC3SCholesterol 24-hydroxylase/0.440
2uxhQUEHTH-type transcriptional regulator TtgR/0.440
3k3ePDBHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.440
3kozZ97D-ornithine 4,5-aminomutase subunit beta/0.440
3ov4EQUSteroid Delta-isomerase5.3.3.10.440
3s1dZIRCytokinin dehydrogenase 11.5.99.120.440
3wbfNAPMeso-diaminopimelate D-dehydrogenase/0.440
4j8tDOGUncharacterized PhzA/B-like protein PA3332/0.440
4y7cFADNADPH--cytochrome P450 reductase/0.440
4ycpFMNtRNA-dihydrouridine(16) synthase/0.440
5cccDDFDihydrofolate reductase1.5.1.30.440
5ch7MD1DMSO reductase family type II enzyme, molybdopterin subunit/0.440
5eioNAP[LysW]-L-2-aminoadipate 6-phosphate reductase/0.440
5hwrCOAHydroxymethylglutaryl-CoA synthase/0.440
5kczNAJAlcohol dehydrogenase E chain1.1.1.10.440