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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2uzwSS4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.11

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2uzwSS4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.111.000
1ydtIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.756
2ojf4PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.713
2oh02PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.628
2f7z6EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.627
2uzvSS5cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.625
2uzuL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.623
2f7e2EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.620
1q8tY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.614
2vo7M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.600
3vqhIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.585
2vo6M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.576
2gu8796cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.572
1ydrIQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.567
1sveI01cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.562
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.560
2uztSS3cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.554
2uw5GVNcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.543
3zo4QWIcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.541
1xhaR68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.539
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.539
2uw0GVKcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.538
3ow3SMYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.536
2c1bCQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.526
4axaRKDcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.518
2jdtI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.516
1q8uH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.514
1vebI05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.514
2vo0M03cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.505
2uw7GVPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.502
3e8eG98cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.499
2gnfY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.495
3kkvB99cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.494
1svhI08cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.492
1xh6R94cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.492
1xh8R55cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.491
1xh5R68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.487
2vo3M04cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.482
1xh7R96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.481
4iazADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.481
2c1aI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.479
1q8wM77cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.477
3e8cG96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.477
3zo1SIJcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.475
1svgI04cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.474
1qmzATPCyclin-dependent kinase 22.7.11.220.473
1bx6BA1cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.469
2jdvL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.469
3aglA03cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.469
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.467
3bwjARXcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.466
4iayADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.466
1j1cADPGlycogen synthase kinase-3 beta2.7.11.260.463
1xh9R69cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.463
4qnyANPMitogen activated protein kinase, putative/0.463
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.461
3l9mL9McAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.461
4fv6E57Mitogen-activated protein kinase 12.7.11.240.458
1jbpADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.455
4iakADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.455
1j1bANPGlycogen synthase kinase-3 beta2.7.11.260.454
1xh4R69cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.453
4oh4ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.452
1rejB1LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.450
4fv5EK9Mitogen-activated protein kinase 12.7.11.240.448
2uvzGVJcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
4gv10XZRAC-alpha serine/threonine-protein kinase2.7.11.10.445
3l9lL9LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.444
2gnlH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443
4mk029XBeta-adrenergic receptor kinase 12.7.11.150.442
4j99ACPFibroblast growth factor receptor 2/0.441
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440