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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2uyhSAHModification methylase HhaI2.1.1.37

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
2uyhSAHModification methylase HhaI2.1.1.371.000
5mhtSAHModification methylase HhaI2.1.1.370.692
9mhtSAHModification methylase HhaI2.1.1.370.684
8mhtSAHModification methylase HhaI2.1.1.370.665
2c7qSAHModification methylase HhaI2.1.1.370.637
7mhtSAHModification methylase HhaI2.1.1.370.622
2i9kSAHModification methylase HhaI2.1.1.370.614
1skmSAHModification methylase HhaI2.1.1.370.612
3mhtSAHModification methylase HhaI2.1.1.370.608
2zcjSAHModification methylase HhaI2.1.1.370.603
2z6uSAHModification methylase HhaI2.1.1.370.590
1fjxSAHModification methylase HhaI2.1.1.370.578
4mhtSAHModification methylase HhaI2.1.1.370.562
10mhSAHModification methylase HhaI2.1.1.370.531
1mhtSAHModification methylase HhaI2.1.1.370.524
2hmySAMModification methylase HhaI2.1.1.370.514
3qv2SAH5-cytosine DNA methyltransferase/0.472
4h0nSAHDnmt2/0.447
4dkjSAHCytosine-specific methyltransferase/0.442