Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2rl5 | 2RL | Vascular endothelial growth factor receptor 2 | 2.7.10.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2rl5 | 2RL | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 1.000 | |
| 3b8q | 900 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.593 | |
| 5bvw | 1N1 | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.575 | |
| 3be2 | RAJ | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.568 | |
| 3ctj | 320 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.566 | |
| 4fny | I3K | ALK tyrosine kinase receptor | 2.7.10.1 | 0.565 | |
| 3oez | STI | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.555 | |
| 3hv3 | R49 | Mitogen-activated protein kinase 14 | / | 0.529 | |
| 2og8 | 1N8 | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.526 | |
| 2oh4 | GIG | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.526 | |
| 2gqg | 1N1 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.525 | |
| 2bak | AQZ | Mitogen-activated protein kinase 14 | / | 0.520 | |
| 4a9y | AQZ | Mitogen-activated protein kinase 14 | / | 0.520 | |
| 2oiq | STI | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.515 | |
| 3gcq | 1BU | Mitogen-activated protein kinase 14 | / | 0.515 | |
| 4tyj | 0LI | Fibroblast growth factor receptor 4 | 2.7.10.1 | 0.513 | |
| 4twn | B96 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.511 | |
| 3prf | FP3 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.510 | |
| 2pl0 | STI | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.509 | |
| 2ofv | 242 | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.506 | |
| 4equ | G6I | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.505 | |
| 2y6o | 1N1 | Ephrin type-A receptor 4 | 2.7.10.1 | 0.504 | |
| 3oct | 1N1 | Tyrosine-protein kinase BTK | 2.7.10.2 | 0.503 | |
| 3eta | 351 | Insulin receptor | 2.7.10.1 | 0.502 | |
| 4eev | L1X | Hepatocyte growth factor receptor | 2.7.10.1 | 0.500 | |
| 3cth | 319 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.499 | |
| 3lfe | Z84 | Mitogen-activated protein kinase 14 | / | 0.498 | |
| 2osc | MUH | Angiopoietin-1 receptor | 2.7.10.1 | 0.497 | |
| 4v01 | 0LI | Fibroblast growth factor receptor 1 (Fms-related tyrosine kinase 2, Pfeiffer syndrome), isoform CRA_b | / | 0.497 | |
| 2g2h | P16 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.496 | |
| 4fk3 | 325 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.496 | |
| 4uxq | 0LI | Fibroblast growth factor receptor 4 | 2.7.10.1 | 0.496 | |
| 2f4j | VX6 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.495 | |
| 2qu5 | 276 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.494 | |
| 3ce3 | 1FN | Hepatocyte growth factor receptor | 2.7.10.1 | 0.493 | |
| 4ase | AV9 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.493 | |
| 4qrc | 0LI | Fibroblast growth factor receptor 4 | 2.7.10.1 | 0.493 | |
| 3vo3 | 0KF | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.492 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.490 | |
| 2hzi | JIN | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.490 | |
| 3ds6 | A17 | Mitogen-activated protein kinase 14 | / | 0.490 | |
| 4dgg | I76 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.490 | |
| 2p2h | 994 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.489 | |
| 3tub | FPU | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.487 | |
| 3b8r | 887 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.486 | |
| 1m17 | AQ4 | Epidermal growth factor receptor | 2.7.10.1 | 0.485 | |
| 4bkj | STI | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.485 | |
| 1m52 | P17 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.484 | |
| 3iw8 | HIZ | Mitogen-activated protein kinase 14 | / | 0.484 | |
| 4ckr | DI1 | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.484 | |
| 4mxx | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.484 | |
| 2dw4 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.483 | |
| 1x8b | 824 | Wee1-like protein kinase | 2.7.10.2 | 0.479 | |
| 2yn8 | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.479 | |
| 3bi6 | 396 | Wee1-like protein kinase | 2.7.10.2 | 0.479 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.479 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.477 | |
| 2xkc | 4VQ | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.477 | |
| 3dko | IHZ | Ephrin type-A receptor 7 | 2.7.10.1 | 0.477 | |
| 4bj9 | UHB | Tankyrase-2 | 2.4.2.30 | 0.477 | |
| 1qpj | STU | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.476 | |
| 3qlg | 1N1 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.476 | |
| 2zm1 | KSF | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.475 | |
| 4ag8 | AXI | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.475 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.475 | |
| 1drf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
| 3ue4 | DB8 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.474 | |
| 3v94 | WYQ | Phosphodiesterase | / | 0.474 | |
| 3vw8 | DF6 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.474 | |
| 4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.474 | |
| 4hni | 16W | Casein kinase I isoform epsilon | 2.7.11.1 | 0.474 | |
| 5iua | 6DX | Adenosine receptor A2a | / | 0.474 | |
| 3qri | 919 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.473 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.472 | |
| 3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.472 | |
| 3l8s | BFF | Mitogen-activated protein kinase 14 | / | 0.472 | |
| 3vrz | VRZ | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.472 | |
| 4feq | 0T8 | Tyrosine-protein kinase receptor TYRO3 | 2.7.10.1 | 0.472 | |
| 1qcf | PP1 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.471 | |
| 3vjo | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.471 | |
| 4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.471 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.470 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
| 3zew | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.470 | |
| 1w83 | L11 | Mitogen-activated protein kinase 14 | / | 0.469 | |
| 1y57 | MPZ | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.469 | |
| 3ac2 | KSE | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.469 | |
| 3biz | 61E | Wee1-like protein kinase | 2.7.10.2 | 0.469 | |
| 3d7z | GK5 | Mitogen-activated protein kinase 14 | / | 0.469 | |
| 4b1f | KRH | Glutamate racemase | / | 0.469 | |
| 4g2f | C07 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.469 | |
| 4i6f | 1C7 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.469 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 1xuo | LA1 | Integrin alpha-L | / | 0.468 | |
| 2vwx | 7X4 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.468 | |
| 3c7q | XIN | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.468 | |
| 3s4q | NK0 | Mitogen-activated protein kinase 14 | / | 0.468 | |
| 4agc | AXI | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.468 | |
| 4jq8 | KJ8 | Epidermal growth factor receptor | 2.7.10.1 | 0.468 | |
| 1s3v | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 2wpx | ACO | Orf14 | / | 0.467 | |
| 1uho | VDN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.466 | |
| 2ivu | ZD6 | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.466 | |
| 3e5a | VX6 | Aurora kinase A | 2.7.11.1 | 0.466 | |
| 3oom | 507 | Activin receptor type-1 | 2.7.11.30 | 0.466 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.466 | |
| 5iu4 | ZMA | Adenosine receptor A2a | / | 0.466 | |
| 2h8h | H8H | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.465 | |
| 2hk5 | 1BM | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.465 | |
| 2itt | AEE | Epidermal growth factor receptor | 2.7.10.1 | 0.465 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.465 | |
| 2z2w | 770 | Wee1-like protein kinase | 2.7.10.2 | 0.465 | |
| 3c1x | CKK | Hepatocyte growth factor receptor | 2.7.10.1 | 0.465 | |
| 3g0f | B49 | Mast/stem cell growth factor receptor Kit | 2.7.10.1 | 0.465 | |
| 3mvm | 39P | Mitogen-activated protein kinase 14 | / | 0.465 | |
| 3w5e | NVW | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.465 | |
| 2a19 | ANP | Interferon-induced, double-stranded RNA-activated protein kinase | 2.7.11.1 | 0.464 | |
| 2dq7 | STU | Tyrosine-protein kinase Fyn | 2.7.10.2 | 0.464 | |
| 3bbt | FMM | Receptor tyrosine-protein kinase erbB-4 | 2.7.10.1 | 0.464 | |
| 3el8 | PD5 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.464 | |
| 3nrr | D16 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.464 | |
| 3qlf | PD5 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.464 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.464 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.464 | |
| 5ajq | DB8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.464 | |
| 5e8x | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.464 | |
| 2ejz | SAH | Diphthine synthase | / | 0.463 | |
| 2hko | FAD | Lysine-specific histone demethylase 1A | 1 | 0.463 | |
| 2nnq | T4B | Fatty acid-binding protein, adipocyte | / | 0.463 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.463 | |
| 2lfo | GCH | Fatty acid-binding protein, liver | / | 0.462 | |
| 3gc9 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.462 | |
| 4c62 | XWW | Tyrosine-protein kinase JAK2 | / | 0.462 | |
| 5uvi | ZMA | Adenosine receptor A2a | / | 0.462 | |
| 1ove | 358 | Mitogen-activated protein kinase 14 | / | 0.461 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.461 | |
| 3d4b | DZD | NAD-dependent protein deacetylase | / | 0.461 | |
| 3itz | P66 | Mitogen-activated protein kinase 14 | / | 0.461 | |
| 4j53 | 1J4 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.461 | |
| 4jq7 | KJQ | Epidermal growth factor receptor | 2.7.10.1 | 0.461 | |
| 2ewa | SB2 | Mitogen-activated protein kinase 14 | / | 0.460 | |
| 2vwz | 7X6 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.460 | |
| 2xk3 | XK3 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.460 | |
| 3cjg | KIM | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.460 | |
| 3vs2 | VSB | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.460 | |
| 2jed | LG8 | Protein kinase C theta type | 2.7.11.13 | 0.459 | |
| 2xyu | Q9G | Ephrin type-A receptor 4 | 2.7.10.1 | 0.459 | |
| 3b2w | 9NH | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.459 | |
| 3hub | 469 | Mitogen-activated protein kinase 14 | / | 0.459 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.459 | |
| 4hvs | 647 | Mast/stem cell growth factor receptor Kit | 2.7.10.1 | 0.459 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.458 | |
| 2i1m | 5CN | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.458 | |
| 2jc6 | QPP | Calcium/calmodulin-dependent protein kinase type 1D | 2.7.11.17 | 0.458 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.458 | |
| 3wg6 | NDP | NADPH-dependent conjugated polyketone reductase C1 | / | 0.458 | |
| 4af3 | VX6 | Aurora kinase B | 2.7.11.1 | 0.458 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.458 | |
| 4g34 | 924 | Eukaryotic translation initiation factor 2-alpha kinase 3 | 2.7.11.1 | 0.458 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.458 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.458 | |
| 4rh1 | 0TT | Spore photoproduct lyase | / | 0.458 | |
| 4xey | 1N1 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.458 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.458 | |
| 3uza | T4G | Adenosine receptor A2a | / | 0.458 | |
| 2io6 | 330 | Wee1-like protein kinase | 2.7.10.2 | 0.457 | |
| 3a4o | STU | Tyrosine-protein kinase Lyn | 2.7.10.2 | 0.457 | |
| 3f82 | 353 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.457 | |
| 3p9t | TCL | Repressor | / | 0.457 | |
| 3tda | PN0 | Cytochrome P450 2D6 | / | 0.457 | |
| 3tvx | PNX | cAMP-specific 3',5'-cyclic phosphodiesterase 4A | 3.1.4.53 | 0.457 | |
| 4bb4 | 32W | Ephrin type-B receptor 4 | 2.7.10.1 | 0.457 | |
| 1uwh | BAX | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.456 | |
| 1xds | DRA | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.456 | |
| 2chw | 039 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.456 | |
| 2jkc | FAD | Flavin-dependent tryptophan halogenase PrnA | 1.14.19.9 | 0.456 | |
| 3bfa | 9OD | Odorant binding protein ASP1 | / | 0.456 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.456 | |
| 3t2k | FAD | Sulfide-quinone reductase | / | 0.456 | |
| 4gi2 | NAP | Crotonyl-CoA carboxylase/reductase | / | 0.456 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.455 | |
| 1q5d | EPB | Epothilone C/D epoxidase | 1.14 | 0.455 | |
| 1trg | CB3 | Thymidylate synthase | / | 0.455 | |
| 2fb8 | 215 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.455 | |
| 2qoq | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.455 | |
| 2xnn | 430 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.455 | |
| 3el7 | PD3 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.455 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.455 | |
| 3up3 | XCA | aceDAF-12 | / | 0.455 | |
| 4j6b | PLO | Cytochrome P450 monooxygenase | / | 0.455 | |
| 4jbt | ASD | Cytochrome P450 monooxygenase | / | 0.455 | |
| 4k9y | K9Y | Focal adhesion kinase 1 | 2.7.10.2 | 0.455 | |
| 4mxo | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.455 | |
| 4wo5 | 324 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.455 | |
| 1vjy | 460 | TGF-beta receptor type-1 | 2.7.11.30 | 0.454 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.454 | |
| 3sl6 | JN8 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.454 | |
| 3sru | Q26 | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 4htx | 19F | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.454 | |
| 5fm7 | ADP | RuvB-like helicase | / | 0.454 | |
| 3rey | XAC | Adenosine receptor A2a | / | 0.454 | |
| 2gtn | LIE | Mitogen-activated protein kinase 14 | / | 0.453 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 3g0e | B49 | Mast/stem cell growth factor receptor Kit | 2.7.10.1 | 0.453 | |
| 3vs4 | VSF | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.453 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.453 | |
| 4gk4 | L90 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.453 | |
| 4jr3 | KJR | Epidermal growth factor receptor | 2.7.10.1 | 0.453 | |
| 4kwi | 1TJ | Reductase homolog | / | 0.453 | |
| 4qmx | H8H | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.453 | |
| 1ezf | IN0 | Squalene synthase | 2.5.1.21 | 0.452 | |
| 1yho | TRR | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 2ph5 | NAD | Homospermidine synthase | / | 0.452 | |
| 4at3 | LTI | BDNF/NT-3 growth factors receptor | 2.7.10.1 | 0.452 | |
| 4bc6 | XZN | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.452 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.452 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.451 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 2xkd | T3M | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.451 | |
| 2zb1 | GK4 | Mitogen-activated protein kinase 14 | / | 0.451 | |
| 3t14 | FAD | Sulfide-quinone reductase | / | 0.451 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.451 | |
| 4i1n | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 4i23 | 1C9 | Epidermal growth factor receptor | 2.7.10.1 | 0.451 | |
| 5f0a | 1FB | cGMP-dependent protein kinase, putative | / | 0.451 | |
| 5iu8 | 6DZ | Adenosine receptor A2a | / | 0.451 | |
| 1fgi | SU1 | Fibroblast growth factor receptor 1 | / | 0.450 | |
| 1r2j | FAD | FkbI | / | 0.450 | |
| 1y2d | 4DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.450 | |
| 2c0o | L2G | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.450 | |
| 2i0e | PDS | Protein kinase C beta type | 2.7.11.13 | 0.450 | |
| 3upk | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.450 | |
| 3vs3 | VSE | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.450 | |
| 3vs6 | VSH | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.450 | |
| 3zh8 | C58 | Protein kinase C iota type | 2.7.11.13 | 0.450 | |
| 4h95 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 4id7 | 1G0 | Activated CDC42 kinase 1 | / | 0.450 | |
| 5dp2 | NAP | CurF | / | 0.450 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1szm | BI4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.449 | |
| 1zg3 | 2HI | Isoflavone 4'-O-methyltransferase | / | 0.449 | |
| 2vx0 | 7X7 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.449 | |
| 2x9f | X9F | Ephrin type-B receptor 4 | 2.7.10.1 | 0.449 | |
| 3aba | FLI | Cytochrome P450 | / | 0.449 | |
| 3cr0 | 809 | Wee1-like protein kinase | 2.7.10.2 | 0.449 | |
| 3e92 | G6A | Mitogen-activated protein kinase 14 | / | 0.449 | |
| 3f5p | 741 | Insulin-like growth factor 1 receptor | 2.7.10.1 | 0.449 | |
| 3is9 | AC7 | Gag-Pol polyprotein | 2.7.7.49 | 0.449 | |
| 3v8w | 0G2 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.449 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 4g31 | 0WH | Eukaryotic translation initiation factor 2-alpha kinase 3 | 2.7.11.1 | 0.449 | |
| 4gg7 | 0J8 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.449 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.449 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1tou | B1V | Fatty acid-binding protein, adipocyte | / | 0.448 | |
| 1uu8 | BI1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.448 | |
| 1v7a | FRC | Adenosine deaminase | 3.5.4.4 | 0.448 | |
| 1xls | REA | Retinoic acid receptor RXR-alpha | / | 0.448 | |
| 2y98 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.448 | |
| 2ze2 | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.448 | |
| 3cqe | P91 | Wee1-like protein kinase | 2.7.10.2 | 0.448 | |
| 3fzt | 4JZ | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.448 | |
| 3td8 | D2R | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 4few | PP2 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.448 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.448 | |
| 4qa0 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.448 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.447 | |
| 1ly4 | COQ | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1qpd | STU | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.447 | |
| 1qxl | FR8 | Adenosine deaminase | 3.5.4.4 | 0.447 | |
| 2itq | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.447 | |
| 2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.447 | |
| 3b9l | AZZ | Serum albumin | / | 0.447 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.447 | |
| 3g58 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.447 | |
| 3uvv | REA | Retinoic acid receptor RXR-alpha | / | 0.447 | |
| 4ajd | F04 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.447 | |
| 4f64 | 0S8 | Fibroblast growth factor receptor 1 | / | 0.447 | |
| 7cat | NDP | Catalase | 1.11.1.6 | 0.447 | |
| 1crb | RTL | Retinol-binding protein 1 | / | 0.446 | |
| 1rgs | CMP | cAMP-dependent protein kinase type I-alpha regulatory subunit | / | 0.446 | |
| 2azz | TCH | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.446 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.446 | |
| 3hu2 | AGS | Transitional endoplasmic reticulum ATPase | 3.6.4.6 | 0.446 | |
| 3k9u | ACO | Spermidine N(1)-acetyltransferase | / | 0.446 | |
| 3ocg | OCG | Mitogen-activated protein kinase 14 | / | 0.446 | |
| 1db4 | 8IN | Phospholipase A2, membrane associated | / | 0.445 | |
| 1o5r | FR9 | Adenosine deaminase | 3.5.4.4 | 0.445 | |
| 2xkf | BX1 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.445 | |
| 2zd1 | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.445 | |
| 3d3p | 20A | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.445 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 3qlh | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.445 | |
| 3qly | 55V | Uncharacterized protein | / | 0.445 | |
| 4b8m | VX6 | Aurora kinase B-A | 2.7.11.1 | 0.445 | |
| 4bgi | I4I | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 4fjz | 4FJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 4qmn | DB8 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.445 | |
| 4xe6 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 3qak | UKA | Adenosine receptor A2a | / | 0.445 | |
| 1mew | XMP | Inosine-5'-monophosphate dehydrogenase | / | 0.444 | |
| 1ndz | FR5 | Adenosine deaminase | 3.5.4.4 | 0.444 | |
| 3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.444 | |
| 3d3e | D3E | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.444 | |
| 3rin | I2O | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 4aot | GW8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.444 | |
| 4ddr | MMV | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 4fhf | 0TT | Spore photoproduct lyase | / | 0.444 | |
| 4qzu | RTL | Retinol-binding protein 2 | / | 0.444 | |
| 4xli | 1N1 | Abelson tyrosine-protein kinase 2 | 2.7.10.2 | 0.444 | |
| 5cp8 | TCU | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1vru | AAP | Gag-Pol polyprotein | 2.7.7.49 | 0.443 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 2bxm | IMN | Serum albumin | / | 0.443 | |
| 2wmq | ZYQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 2yac | 937 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.443 | |
| 2ym3 | YM3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 2zb8 | IMN | Prostaglandin reductase 2 | 1.3.1.48 | 0.443 | |
| 3ac1 | KZI | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.443 | |
| 4c58 | 824 | Cyclin-G-associated kinase | 2.7.11.1 | 0.443 | |
| 4c77 | N01 | Phenylacetone monooxygenase | 1.14.13.92 | 0.443 | |
| 4cjx | 9L9 | C-1-tetrahydrofolate synthase, cytoplasmic, putative | / | 0.443 | |
| 4eh6 | 0ON | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 4hf4 | 15H | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.443 | |
| 4i22 | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.443 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1syn | F89 | Thymidylate synthase | / | 0.442 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 2xk7 | 30E | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.442 | |
| 2ydi | YDI | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 2ydo | ADN | Adenosine receptor A2a | / | 0.442 | |
| 3bhe | BZN | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 3c0g | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.442 | |
| 3sgv | 2BJ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.442 | |
| 4a2a | ATP | Cell division protein FtsA | / | 0.442 | |
| 4a4o | 664 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.442 | |
| 4e37 | NDP | Catalase | 1.11.1.6 | 0.442 | |
| 4f1s | F1S | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 4ocv | ANP | Aminoglycoside phosphotransferase | / | 0.442 | |
| 4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.442 | |
| 4uhr | NGI | Adenosine receptor A2a | / | 0.442 | |
| 3uzc | T4E | Adenosine receptor A2a | / | 0.442 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.441 | |
| 1ne6 | SP1 | cAMP-dependent protein kinase type I-alpha regulatory subunit | / | 0.441 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.441 | |
| 1rd4 | L08 | Integrin alpha-L | / | 0.441 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 2j4z | 626 | Aurora kinase A | 2.7.11.1 | 0.441 | |
| 2py3 | ACP | Fibroblast growth factor receptor 2 | / | 0.441 | |
| 2ykb | YKB | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.441 | |
| 3ac3 | KSH | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.441 | |
| 3c1t | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.441 | |
| 3clb | TMQ | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.441 | |
| 3fco | IIG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3n5x | XFK | Nitric oxide synthase, brain | 1.14.13.39 | 0.441 | |
| 3oq1 | 3OQ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
| 3std | MQ0 | Scytalone dehydratase | 4.2.1.94 | 0.441 | |
| 3zia | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.441 | |
| 4afe | GGY | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.441 | |
| 4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 4dym | IYZ | Activin receptor type-1 | 2.7.11.30 | 0.441 | |
| 4gqk | ADP | Actin cross-linking toxin VgrG1 | / | 0.441 | |
| 4j52 | 1J3 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.441 | |
| 4jlk | 1NO | Deoxycytidine kinase | 2.7.1.74 | 0.441 | |
| 4llk | MEW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
| 2eb3 | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.440 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 2vx1 | 7X8 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.440 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.440 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.440 | |
| 3wi2 | P98 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.440 | |
| 4acg | 6LQ | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.440 | |
| 4bb6 | HD1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 | |
| 4elb | 34S | Dihydrofolate reductase | / | 0.440 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.440 | |
| 4jrv | KJV | Epidermal growth factor receptor | 2.7.10.1 | 0.440 |