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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2rl52RLVascular endothelial growth factor receptor 22.7.10.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
2rl52RLVascular endothelial growth factor receptor 22.7.10.11.000
3b8q900Vascular endothelial growth factor receptor 22.7.10.10.593
5bvw1N1Epithelial discoidin domain-containing receptor 12.7.10.10.575
3be2RAJVascular endothelial growth factor receptor 22.7.10.10.568
3ctj320Hepatocyte growth factor receptor2.7.10.10.566
4fnyI3KALK tyrosine kinase receptor2.7.10.10.565
3oezSTIProto-oncogene tyrosine-protein kinase Src2.7.10.20.555
3hv3R49Mitogen-activated protein kinase 14/0.529
2og81N8Tyrosine-protein kinase Lck2.7.10.20.526
2oh4GIGVascular endothelial growth factor receptor 22.7.10.10.526
2gqg1N1Tyrosine-protein kinase ABL12.7.10.20.525
2bakAQZMitogen-activated protein kinase 14/0.520
4a9yAQZMitogen-activated protein kinase 14/0.520
2oiqSTIProto-oncogene tyrosine-protein kinase Src2.7.10.20.515
3gcq1BUMitogen-activated protein kinase 14/0.515
4tyj0LIFibroblast growth factor receptor 42.7.10.10.513
4twnB96Ephrin type-A receptor 32.7.10.10.511
3prfFP3Serine/threonine-protein kinase B-raf2.7.11.10.510
2pl0STITyrosine-protein kinase Lck2.7.10.20.509
2ofv242Tyrosine-protein kinase Lck2.7.10.20.506
4equG6ISerine/threonine-protein kinase 102.7.11.10.505
2y6o1N1Ephrin type-A receptor 42.7.10.10.504
3oct1N1Tyrosine-protein kinase BTK2.7.10.20.503
3eta351Insulin receptor2.7.10.10.502
4eevL1XHepatocyte growth factor receptor2.7.10.10.500
3cth319Hepatocyte growth factor receptor2.7.10.10.499
3lfeZ84Mitogen-activated protein kinase 14/0.498
2oscMUHAngiopoietin-1 receptor2.7.10.10.497
4v010LIFibroblast growth factor receptor 1 (Fms-related tyrosine kinase 2, Pfeiffer syndrome), isoform CRA_b/0.497
2g2hP16Tyrosine-protein kinase ABL12.7.10.20.496
4fk3325Serine/threonine-protein kinase B-raf2.7.11.10.496
4uxq0LIFibroblast growth factor receptor 42.7.10.10.496
2f4jVX6Tyrosine-protein kinase ABL12.7.10.20.495
2qu5276Vascular endothelial growth factor receptor 22.7.10.10.494
3ce31FNHepatocyte growth factor receptor2.7.10.10.493
4aseAV9Vascular endothelial growth factor receptor 22.7.10.10.493
4qrc0LIFibroblast growth factor receptor 42.7.10.10.493
3vo30KFVascular endothelial growth factor receptor 22.7.10.10.492
1bygSTUTyrosine-protein kinase CSK/0.490
2hziJINTyrosine-protein kinase ABL12.7.10.20.490
3ds6A17Mitogen-activated protein kinase 14/0.490
4dggI76Proto-oncogene tyrosine-protein kinase Src2.7.10.20.490
2p2h994Vascular endothelial growth factor receptor 22.7.10.10.489
3tubFPUTyrosine-protein kinase SYK2.7.10.20.487
3b8r887Vascular endothelial growth factor receptor 22.7.10.10.486
1m17AQ4Epidermal growth factor receptor2.7.10.10.485
4bkjSTIEpithelial discoidin domain-containing receptor 12.7.10.10.485
1m52P17Tyrosine-protein kinase ABL12.7.10.20.484
3iw8HIZMitogen-activated protein kinase 14/0.484
4ckrDI1Epithelial discoidin domain-containing receptor 12.7.10.10.484
4mxxDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.484
2dw4FADLysine-specific histone demethylase 1A10.483
1x8b824Wee1-like protein kinase2.7.10.20.479
2yn8STUEphrin type-B receptor 42.7.10.10.479
3bi6396Wee1-like protein kinase2.7.10.20.479
3emlZMAAdenosine receptor A2a/0.479
2qo9ANPEphrin type-A receptor 32.7.10.10.477
2xkc4VQSerine/threonine-protein kinase Nek22.7.11.10.477
3dkoIHZEphrin type-A receptor 72.7.10.10.477
4bj9UHBTankyrase-22.4.2.300.477
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.476
3qlg1N1Proto-oncogene tyrosine-protein kinase Src2.7.10.20.476
2zm1KSFTyrosine-protein kinase Lck2.7.10.20.475
4ag8AXIVascular endothelial growth factor receptor 22.7.10.10.475
4b144XBGlycylpeptide N-tetradecanoyltransferase/0.475
1drfFOLDihydrofolate reductase1.5.1.30.474
3ue4DB8Tyrosine-protein kinase ABL12.7.10.20.474
3v94WYQPhosphodiesterase/0.474
3vw8DF6Hepatocyte growth factor receptor2.7.10.10.474
4gk2L66Ephrin type-A receptor 32.7.10.10.474
4hni16WCasein kinase I isoform epsilon2.7.11.10.474
5iua6DXAdenosine receptor A2a/0.474
3qri919Tyrosine-protein kinase ABL12.7.10.20.473
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.472
3gytDL4Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.472
3l8sBFFMitogen-activated protein kinase 14/0.472
3vrzVRZTyrosine-protein kinase HCK2.7.10.20.472
4feq0T8Tyrosine-protein kinase receptor TYRO32.7.10.10.472
1qcfPP1Tyrosine-protein kinase HCK2.7.10.20.471
3vjoANPEpidermal growth factor receptor2.7.10.10.471
4bbxLKFcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.471
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.470
1pd9CO4Dihydrofolate reductase1.5.1.30.470
3zewSTUEphrin type-B receptor 42.7.10.10.470
1w83L11Mitogen-activated protein kinase 14/0.469
1y57MPZProto-oncogene tyrosine-protein kinase Src2.7.10.20.469
3ac2KSETyrosine-protein kinase Lck2.7.10.20.469
3biz61EWee1-like protein kinase2.7.10.20.469
3d7zGK5Mitogen-activated protein kinase 14/0.469
4b1fKRHGlutamate racemase/0.469
4g2fC07Ephrin type-A receptor 32.7.10.10.469
4i6f1C7Serine/threonine-protein kinase PLK22.7.11.210.469
1mvsDTMDihydrofolate reductase1.5.1.30.468
1xuoLA1Integrin alpha-L/0.468
2vwx7X4Ephrin type-B receptor 42.7.10.10.468
3c7qXINVascular endothelial growth factor receptor 22.7.10.10.468
3s4qNK0Mitogen-activated protein kinase 14/0.468
4agcAXIVascular endothelial growth factor receptor 22.7.10.10.468
4jq8KJ8Epidermal growth factor receptor2.7.10.10.468
1s3vTQDDihydrofolate reductase1.5.1.30.467
2wpxACOOrf14/0.467
1uhoVDNcGMP-specific 3',5'-cyclic phosphodiesterase/0.466
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.466
3e5aVX6Aurora kinase A2.7.11.10.466
3oom507Activin receptor type-12.7.11.300.466
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.466
5iu4ZMAAdenosine receptor A2a/0.466
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.465
2hk51BMTyrosine-protein kinase HCK2.7.10.20.465
2ittAEEEpidermal growth factor receptor2.7.10.10.465
2vn0TDZCytochrome P450 2C8/0.465
2z2w770Wee1-like protein kinase2.7.10.20.465
3c1xCKKHepatocyte growth factor receptor2.7.10.10.465
3g0fB49Mast/stem cell growth factor receptor Kit2.7.10.10.465
3mvm39PMitogen-activated protein kinase 14/0.465
3w5eNVWcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.465
2a19ANPInterferon-induced, double-stranded RNA-activated protein kinase2.7.11.10.464
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.464
3bbtFMMReceptor tyrosine-protein kinase erbB-42.7.10.10.464
3el8PD5Proto-oncogene tyrosine-protein kinase Src2.7.10.20.464
3nrrD16Bifunctional dihydrofolate reductase-thymidylate synthase/0.464
3qlfPD5Proto-oncogene tyrosine-protein kinase Src2.7.10.20.464
4b13X25Glycylpeptide N-tetradecanoyltransferase/0.464
4j6dTESCytochrome P450 monooxygenase/0.464
5ajqDB8Serine/threonine-protein kinase 102.7.11.10.464
5e8xSTUTGF-beta receptor type-12.7.11.300.464
2ejzSAHDiphthine synthase/0.463
2hkoFADLysine-specific histone demethylase 1A10.463
2nnqT4BFatty acid-binding protein, adipocyte/0.463
3ssnMVIMycinamicin VI 2''-O-methyltransferase/0.463
2lfoGCHFatty acid-binding protein, liver/0.462
3gc9B45Mitogen-activated protein kinase 112.7.11.240.462
4c62XWWTyrosine-protein kinase JAK2/0.462
5uviZMAAdenosine receptor A2a/0.462
1ove358Mitogen-activated protein kinase 14/0.461
2d29FADAcyl-CoA dehydrogenase/0.461
3d4bDZDNAD-dependent protein deacetylase/0.461
3itzP66Mitogen-activated protein kinase 14/0.461
4j531J4Serine/threonine-protein kinase PLK12.7.11.210.461
4jq7KJQEpidermal growth factor receptor2.7.10.10.461
2ewaSB2Mitogen-activated protein kinase 14/0.460
2vwz7X6Ephrin type-B receptor 42.7.10.10.460
2xk3XK3Serine/threonine-protein kinase Nek22.7.11.10.460
3cjgKIMVascular endothelial growth factor receptor 22.7.10.10.460
3vs2VSBTyrosine-protein kinase HCK2.7.10.20.460
2jedLG8Protein kinase C theta type2.7.11.130.459
2xyuQ9GEphrin type-A receptor 42.7.10.10.459
3b2w9NHTyrosine-protein kinase Lck2.7.10.20.459
3hub469Mitogen-activated protein kinase 14/0.459
3l0lHC3Nuclear receptor ROR-gamma/0.459
4hvs647Mast/stem cell growth factor receptor Kit2.7.10.10.459
1blzACVIsopenicillin N synthase1.21.3.10.458
1hb1OCVIsopenicillin N synthase1.21.3.10.458
1upw444Oxysterols receptor LXR-beta/0.458
2i1m5CNMacrophage colony-stimulating factor 1 receptor2.7.10.10.458
2jc6QPPCalcium/calmodulin-dependent protein kinase type 1D2.7.11.170.458
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.458
3wg6NDPNADPH-dependent conjugated polyketone reductase C1/0.458
4af3VX6Aurora kinase B2.7.11.10.458
4b12C23Glycylpeptide N-tetradecanoyltransferase/0.458
4g34924Eukaryotic translation initiation factor 2-alpha kinase 32.7.11.10.458
4j6cSTRCytochrome P450 monooxygenase/0.458
4jib1L6cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.458
4rh10TTSpore photoproduct lyase/0.458
4xey1N1Tyrosine-protein kinase ABL12.7.10.20.458
5k2bZMAAdenosine receptor A2a/0.458
3uzaT4GAdenosine receptor A2a/0.458
2io6330Wee1-like protein kinase2.7.10.20.457
3a4oSTUTyrosine-protein kinase Lyn2.7.10.20.457
3f82353Hepatocyte growth factor receptor2.7.10.10.457
3p9tTCLRepressor/0.457
3tdaPN0Cytochrome P450 2D6/0.457
3tvxPNXcAMP-specific 3',5'-cyclic phosphodiesterase 4A3.1.4.530.457
4bb432WEphrin type-B receptor 42.7.10.10.457
1uwhBAXSerine/threonine-protein kinase B-raf2.7.11.10.456
1xdsDRAAclacinomycin 10-hydroxylase RdmB4.1.10.456
2chw039Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.456
2jkcFADFlavin-dependent tryptophan halogenase PrnA1.14.19.90.456
3bfa9ODOdorant binding protein ASP1/0.456
3pqbVGPPutative oxidoreductase/0.456
3t2kFADSulfide-quinone reductase/0.456
4gi2NAPCrotonyl-CoA carboxylase/reductase/0.456
1fmjRTLRetinol dehydratase/0.455
1q5dEPBEpothilone C/D epoxidase1.140.455
1trgCB3Thymidylate synthase/0.455
2fb8215Serine/threonine-protein kinase B-raf2.7.11.10.455
2qoqANPEphrin type-A receptor 32.7.10.10.455
2xnn430Serine/threonine-protein kinase Nek22.7.11.10.455
3el7PD3Proto-oncogene tyrosine-protein kinase Src2.7.10.20.455
3qm4PN0Cytochrome P450 2D6/0.455
3up3XCAaceDAF-12/0.455
4j6bPLOCytochrome P450 monooxygenase/0.455
4jbtASDCytochrome P450 monooxygenase/0.455
4k9yK9YFocal adhesion kinase 12.7.10.20.455
4mxoDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.455
4wo5324Serine/threonine-protein kinase B-raf2.7.11.10.455
1vjy460TGF-beta receptor type-12.7.11.300.454
3a1l2CCCytochrome P450/0.454
3sl6JN8cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.454
3sruQ26Dihydrofolate reductase1.5.1.30.454
4htx19FcGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.454
5fm7ADPRuvB-like helicase/0.454
3reyXACAdenosine receptor A2a/0.454
2gtnLIEMitogen-activated protein kinase 14/0.453
2y60M8FIsopenicillin N synthase1.21.3.10.453
3g0eB49Mast/stem cell growth factor receptor Kit2.7.10.10.453
3vs4VSFTyrosine-protein kinase HCK2.7.10.20.453
3vtbTKAVitamin D3 receptor/0.453
4gk4L90Ephrin type-A receptor 32.7.10.10.453
4jr3KJREpidermal growth factor receptor2.7.10.10.453
4kwi1TJReductase homolog/0.453
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.453
1ezfIN0Squalene synthase2.5.1.210.452
1yhoTRRDihydrofolate reductase1.5.1.30.452
2ph5NADHomospermidine synthase/0.452
4at3LTIBDNF/NT-3 growth factors receptor2.7.10.10.452
4bc6XZNSerine/threonine-protein kinase 102.7.11.10.452
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.452
1cqp803Integrin alpha-L/0.451
1s3uTQDDihydrofolate reductase1.5.1.30.451
2xkdT3MSerine/threonine-protein kinase Nek22.7.11.10.451
2zb1GK4Mitogen-activated protein kinase 14/0.451
3t14FADSulfide-quinone reductase/0.451
3zoiM2WIsopenicillin N synthase1.21.3.10.451
4b117I1Glycylpeptide N-tetradecanoyltransferase/0.451
4i1nFOLDihydrofolate reductase1.5.1.30.451
4i231C9Epidermal growth factor receptor2.7.10.10.451
5f0a1FBcGMP-dependent protein kinase, putative/0.451
5iu86DZAdenosine receptor A2a/0.451
1fgiSU1Fibroblast growth factor receptor 1/0.450
1r2jFADFkbI/0.450
1y2d4DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.450
2c0oL2GTyrosine-protein kinase HCK2.7.10.20.450
2i0ePDSProtein kinase C beta type2.7.11.130.450
3upkUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.450
3vs3VSETyrosine-protein kinase HCK2.7.10.20.450
3vs6VSHTyrosine-protein kinase HCK2.7.10.20.450
3zh8C58Protein kinase C iota type2.7.11.130.450
4h9506UDihydrofolate reductase1.5.1.30.450
4id71G0Activated CDC42 kinase 1/0.450
5dp2NAPCurF/0.450
1mvtDTMDihydrofolate reductase1.5.1.30.449
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.449
1zg32HIIsoflavone 4'-O-methyltransferase/0.449
2vx07X7Ephrin type-B receptor 42.7.10.10.449
2x9fX9FEphrin type-B receptor 42.7.10.10.449
3abaFLICytochrome P450/0.449
3cr0809Wee1-like protein kinase2.7.10.20.449
3e92G6AMitogen-activated protein kinase 14/0.449
3f5p741Insulin-like growth factor 1 receptor2.7.10.10.449
3is9AC7Gag-Pol polyprotein2.7.7.490.449
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.449
3zkyWT4Isopenicillin N synthase1.21.3.10.449
4g310WHEukaryotic translation initiation factor 2-alpha kinase 32.7.11.10.449
4gg70J8Hepatocyte growth factor receptor2.7.10.10.449
4jlj1NMDeoxycytidine kinase2.7.1.740.449
1ia4TQ6Dihydrofolate reductase1.5.1.30.448
1touB1VFatty acid-binding protein, adipocyte/0.448
1uu8BI13-phosphoinositide-dependent protein kinase 12.7.11.10.448
1v7aFRCAdenosine deaminase3.5.4.40.448
1xlsREARetinoic acid receptor RXR-alpha/0.448
2y98MIVMycinamicin IV hydroxylase/epoxidase/0.448
2ze2T27Gag-Pol polyprotein2.7.7.490.448
3cqeP91Wee1-like protein kinase2.7.10.20.448
3fzt4JZProtein-tyrosine kinase 2-beta2.7.10.20.448
3td8D2RDihydrofolate reductase1.5.1.30.448
4fewPP2Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.448
4gk3L87Ephrin type-A receptor 32.7.10.10.448
4qa0SHHHistone deacetylase 83.5.1.980.448
1jioDEB6-deoxyerythronolide B hydroxylase/0.447
1ly4COQDihydrofolate reductase1.5.1.30.447
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.447
1qxlFR8Adenosine deaminase3.5.4.40.447
2itqITQEpidermal growth factor receptor2.7.10.10.447
2yneYNEGlycylpeptide N-tetradecanoyltransferase/0.447
3b9lAZZSerum albumin/0.447
3g45988cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.447
3g58988cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.447
3uvvREARetinoic acid receptor RXR-alpha/0.447
4ajdF04cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.447
4f640S8Fibroblast growth factor receptor 1/0.447
7catNDPCatalase1.11.1.60.447
1crbRTLRetinol-binding protein 1/0.446
1rgsCMPcAMP-dependent protein kinase type I-alpha regulatory subunit/0.446
2azzTCHPhospholipase A2, major isoenzyme3.1.1.40.446
2po7CHDFerrochelatase, mitochondrial4.99.1.10.446
3hu2AGSTransitional endoplasmic reticulum ATPase3.6.4.60.446
3k9uACOSpermidine N(1)-acetyltransferase/0.446
3ocgOCGMitogen-activated protein kinase 14/0.446
1db48INPhospholipase A2, membrane associated/0.445
1o5rFR9Adenosine deaminase3.5.4.40.445
2xkfBX1Serine/threonine-protein kinase Nek22.7.11.10.445
2zd1T27Gag-Pol polyprotein2.7.7.490.445
3d3p20AcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.445
3oafOAGDihydrofolate reductase1.5.1.30.445
3qlhT27Gag-Pol polyprotein2.7.7.490.445
3qly55VUncharacterized protein/0.445
4b8mVX6Aurora kinase B-A2.7.11.10.445
4bgiI4IEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.445
4fjz4FJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
4qmnDB8Serine/threonine-protein kinase 242.7.11.10.445
4xe606UDihydrofolate reductase1.5.1.30.445
3qakUKAAdenosine receptor A2a/0.445
1mewXMPInosine-5'-monophosphate dehydrogenase/0.444
1ndzFR5Adenosine deaminase3.5.4.40.444
3byzH11Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.444
3d3eD3ECorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.444
3rinI2OMitogen-activated protein kinase 14/0.444
4aotGW8Serine/threonine-protein kinase 102.7.11.10.444
4ddrMMVDihydrofolate reductase1.5.1.30.444
4fhf0TTSpore photoproduct lyase/0.444
4qzuRTLRetinol-binding protein 2/0.444
4xli1N1Abelson tyrosine-protein kinase 22.7.10.20.444
5cp8TCUEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.444
1ia3TQ5Dihydrofolate reductase1.5.1.30.443
1vruAAPGag-Pol polyprotein2.7.7.490.443
1w06W05Isopenicillin N synthase1.21.3.10.443
2bxmIMNSerum albumin/0.443
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.443
2yac937Serine/threonine-protein kinase PLK12.7.11.210.443
2ym3YM3Serine/threonine-protein kinase Chk12.7.11.10.443
2zb8IMNProstaglandin reductase 21.3.1.480.443
3ac1KZITyrosine-protein kinase Lck2.7.10.20.443
4c58824Cyclin-G-associated kinase2.7.11.10.443
4c77N01Phenylacetone monooxygenase1.14.13.920.443
4cjx9L9C-1-tetrahydrofolate synthase, cytoplasmic, putative/0.443
4eh60ONMitogen-activated protein kinase 14/0.443
4hf415HcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.443
4i22IREEpidermal growth factor receptor2.7.10.10.443
1hfqMOTDihydrofolate reductase1.5.1.30.442
1synF89Thymidylate synthase/0.442
1uzwCDHIsopenicillin N synthase1.21.3.10.442
2xk730ESerine/threonine-protein kinase Nek22.7.11.10.442
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.442
2ydoADNAdenosine receptor A2a/0.442
3bheBZNGag-Pol polyprotein3.4.23.160.442
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.442
3sgv2BJDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.442
4a2aATPCell division protein FtsA/0.442
4a4o664Serine/threonine-protein kinase PLK12.7.11.210.442
4e37NDPCatalase1.11.1.60.442
4f1sF1SPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
4ocvANPAminoglycoside phosphotransferase/0.442
4rlh0WEEnoyl-[acyl-carrier-protein] reductase [NADH]/0.442
4uhrNGIAdenosine receptor A2a/0.442
3uzcT4EAdenosine receptor A2a/0.442
1jpaANPEphrin type-B receptor 22.7.10.10.441
1ne6SP1cAMP-dependent protein kinase type I-alpha regulatory subunit/0.441
1pqc444Oxysterols receptor LXR-beta/0.441
1rd4L08Integrin alpha-L/0.441
2aq8NAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
2bu9HFVIsopenicillin N synthase1.21.3.10.441
2j4z626Aurora kinase A2.7.11.10.441
2py3ACPFibroblast growth factor receptor 2/0.441
2ykbYKBHeat shock protein HSP 90-alpha/0.441
2zbaZBATrichothecene 3-O-acetyltransferase/0.441
3ac3KSHTyrosine-protein kinase Lck2.7.10.20.441
3c1tMYCDihydroflavonol 4-reductase1.1.1.2190.441
3clbTMQBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.441
3fcoIIGCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.441
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
3n5xXFKNitric oxide synthase, brain1.14.13.390.441
3oq13OQCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.441
3stdMQ0Scytalone dehydratase4.2.1.940.441
3ziaADPATP synthase subunit beta, mitochondrial3.6.3.140.441
4afeGGYSerine/threonine-protein kinase Nek22.7.11.10.441
4biiPYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
4dymIYZActivin receptor type-12.7.11.300.441
4gqkADPActin cross-linking toxin VgrG1/0.441
4j521J3Serine/threonine-protein kinase PLK12.7.11.210.441
4jlk1NODeoxycytidine kinase2.7.1.740.441
4llkMEWcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.441
2eb3ANPEpidermal growth factor receptor2.7.10.10.440
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.440
2jb4A14Isopenicillin N synthase1.21.3.10.440
2vx17X8Ephrin type-B receptor 42.7.10.10.440
3mdmFJZCholesterol 24-hydroxylase/0.440
3slkNDPPolyketide synthase extender module 2/0.440
3wi2P98cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.440
4acg6LQGlycogen synthase kinase-3 beta2.7.11.260.440
4bb6HD1Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.440
4elb34SDihydrofolate reductase/0.440
4iarERM5-hydroxytryptamine receptor 1B/0.440
4jrvKJVEpidermal growth factor receptor2.7.10.10.440