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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2rh9IGPTryptophan synthase alpha chain

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2rh9IGPTryptophan synthase alpha chain/1.000
1kfbIGPTryptophan synthase alpha chain/0.759
2rhgIGPTryptophan synthase alpha chain/0.728
1beuIPLTryptophan synthase alpha chain/0.703
1k7fIAVTryptophan synthase alpha chain/0.675
1kfcIPLTryptophan synthase alpha chain/0.656
1qoqIGPTryptophan synthase alpha chain/0.649
1k8y13PTryptophan synthase alpha chain/0.575
1a5sFIPTryptophan synthase alpha chain/0.548
2clfF6FTryptophan synthase alpha chain/0.548
4zqcF6FTryptophan synthase alpha chain/0.532
1a5bIGPTryptophan synthase alpha chain/0.522
4y6gF6FTryptophan synthase alpha chain/0.519
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.508
4boeCLRJapanin/0.502
4g7gVFVLanosterol 14-alpha-demethylase/0.501
4yr9NADL-threonine 3-dehydrogenase, mitochondrial1.1.1.1030.499
2i4jDRJPeroxisome proliferator-activated receptor gamma/0.495
2uxoTACHTH-type transcriptional regulator TtgR/0.495
1xddAAYIntegrin alpha-L/0.494
2rlcCHDCholoylglycine hydrolase3.5.1.240.494
2clmF6FTryptophan synthase alpha chain/0.491
1kkq471Peroxisome proliferator-activated receptor alpha/0.487
3em0CHDFatty acid-binding protein 6, ileal (gastrotropin)/0.486
2xc3RT8Steroid C26-monooxygenase1.14.13.1410.485
3k1wBFXRenin3.4.23.150.485
3g70A5TRenin3.4.23.150.484
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.482
4eywL0RCarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.482
1bvrNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.481
1ddsMTXDihydrofolate reductase1.5.1.30.480
3f03FMNPentaerythritol tetranitrate reductase/0.480
4du82P0Mevalonate diphosphate decarboxylase/0.480
1f8gNADNAD(P) transhydrogenase subunit alpha part 11.6.1.20.479
3u9eCOALmo1369 protein/0.479
4iqlFMNEnoyl-(Acyl-carrier-protein) reductase II/0.479
4ocpADPN-acetylhexosamine 1-kinase2.7.1.1620.479
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.477
2trsIPLTryptophan synthase alpha chain/0.477
3ixp834Ecdysone receptor/0.476
2jkkBI9Focal adhesion kinase 12.7.10.20.475
3atzFMNProstaglandin F2a synthase/0.475
1bwlFMNNADPH dehydrogenase 11.6.99.10.474
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.474
2clhF19Tryptophan synthase alpha chain/0.474
2znnS44Peroxisome proliferator-activated receptor alpha/0.474
3irm1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.474
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.474
1h73ANPHomoserine kinase2.7.1.390.473
3ibqATPPyridoxal kinase/0.473
4m4922YL-lactate dehydrogenase A chain1.1.1.270.473
4nbwNADShort-chain dehydrogenase/reductase SDR/0.473
1draMTXDihydrofolate reductase1.5.1.30.472
2pobGW4Peroxisome proliferator-activated receptor gamma/0.472
1zgyBRLPeroxisome proliferator-activated receptor gamma/0.471
2cleF6FTryptophan synthase alpha chain/0.471
2g1r3IGRenin3.4.23.150.471
3p82FMNPentaerythritol tetranitrate reductase/0.471
1zrzBI1Protein kinase C iota type2.7.11.130.470
3h3sH15Collagen type IV alpha-3-binding protein/0.470
4g9kFADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.470
1gg5FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.469
3jziJZLBiotin carboxylase6.3.4.140.469
4bc7FADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.469
4o1mNADEnoyl-acyl carrier reductase/0.469
2iyfERYOleandomycin glycosyltransferase2.4.10.468
2jj2ANPATP synthase subunit beta, mitochondrial3.6.3.140.468
4bquCLRJapanin/0.468
5a9sNAPPutative dehydrogenase/0.468
2d29FADAcyl-CoA dehydrogenase/0.467
3b6zCO7Enoyl reductase LovC10.467
3h3qH13Collagen type IV alpha-3-binding protein/0.467
4eji0QACytochrome P450 2A131.14.14.10.467
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.466
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.466
3hyoADPPyridoxal kinase/0.466
4opgFDAConserved Archaeal protein/0.466
4u03GTPCyclic GMP-AMP synthase/0.466
1me6IVSPlasmepsin-23.4.23.390.465
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.465
2il2LIXRenin3.4.23.150.465
2xw19NVSerum albumin/0.465
4k6fNAPPutative Acetoacetyl-CoA reductase/0.465
4wx2F6FTryptophan synthase alpha chain/0.465
4wx2F6FTryptophan synthase beta chain4.2.1.200.465
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.464
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.464
1qy5NECEndoplasmin/0.464
2i4zDRHPeroxisome proliferator-activated receptor gamma/0.464
2w9hTOPDihydrofolate reductase1.5.1.30.464
3mpjFADGlutaryl-CoA dehydrogenase1.3.99.320.464
4x7uZM3Mycinamicin III 3''-O-methyltransferase2.1.1.2370.464
1jolFFODihydrofolate reductase1.5.1.30.463
2a94AP0L-lactate dehydrogenase1.1.1.270.463
4bfuZVUPantothenate kinase2.7.1.330.463
4biiPYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.463
4dquNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.463
4nbtNAD3-oxoacyl-[acyl-carrier-protein] reductase/0.463
4oplFDAConserved Archaeal protein/0.463
1mvsDTMDihydrofolate reductase1.5.1.30.462
1rb3MTXDihydrofolate reductase1.5.1.30.462
1tj0FADBifunctional protein PutA1.5.5.20.462
1wxjIPLTryptophan synthase alpha chain/0.462
2rqfJH3Hemolymph juvenile hormone binding protein/0.462
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.462
3oadLPORenin3.4.23.150.462
3p62FMNPentaerythritol tetranitrate reductase/0.462
3rudNADUDP-N-acetylglucosamine 4-epimerase/0.462
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.462
4x7zZM3Mycinamicin III 3''-O-methyltransferase2.1.1.2370.462
1bwsNDPGDP-L-fucose synthase/0.461
1h69FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.461
1kzjCB3Thymidylate synthase/0.461
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.461
3gbuATPUncharacterized sugar kinase PH14592.7.10.461
4bfvZVVPantothenate kinase2.7.1.330.461
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.461
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.461
1k8zIAGTryptophan synthase alpha chain/0.460
1xe55FEPlasmepsin-23.4.23.390.460
2bjfDXCCholoylglycine hydrolase3.5.1.240.460
2g1y5IGRenin3.4.23.150.460
2v9jATP5'-AMP-activated protein kinase subunit gamma-1/0.460
4a81DXCMajor pollen allergen Bet v 1-A/0.460
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.460
4eudCOASuccinyl-CoA:acetate CoA-transferase/0.460
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.460
1k7l544Peroxisome proliferator-activated receptor alpha/0.459
1p0hACOMycothiol acetyltransferase2.3.1.1890.459
1xe65FPPlasmepsin-23.4.23.390.459
2cy0NAPShikimate dehydrogenase (NADP(+))/0.459
2drcMTXDihydrofolate reductase1.5.1.30.459
2ejkSAHDiphthine synthase/0.459
2emuSAHDiphthine synthase/0.459
2i4pDRHPeroxisome proliferator-activated receptor gamma/0.459
2ohvNHLGlutamate racemase/0.459
2qimZEAClass 10 plant pathogenesis-related protein/0.459
2vn0TDZCytochrome P450 2C8/0.459
2yxuATPPyridoxal kinase2.7.1.350.459
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.459
3gw9VNILanosterol 14-alpha-demethylase/0.459
3phiNDPShikimate dehydrogenase (NADP(+))/0.459
4dfrMTXDihydrofolate reductase1.5.1.30.459
4e2bFMNDehydrogenase/0.459
4i13FOLDihydrofolate reductase1.5.1.30.459
4yswFADXanthine dehydrogenase/oxidase/0.459
1hygNAPL-2-hydroxycarboxylate dehydrogenase (NAD(P)(+))/0.458
1n77ATPGlutamate--tRNA ligase6.1.1.170.458
2c27ACOMycothiol acetyltransferase2.3.1.1890.458
4a8v2ANMajor pollen allergen Bet v 1-J/0.458
4iarERM5-hydroxytryptamine receptor 1B/0.458
4k28NADShikimate dehydrogenase family protein/0.458
5hwoHMGHydroxymethylglutaryl-CoA synthase/0.458
1re7FOLDihydrofolate reductase1.5.1.30.457
1x1cSAHC-20 methyltransferase/0.457
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.457
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.457
3gqvNAPEnoyl reductase LovC10.457
3gwfNAPCyclohexanone monooxygenase/0.457
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.457
4ct1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.457
4eakATP5'-AMP-activated protein kinase subunit gamma-1/0.457
4g3jVNTLanosterol 14-alpha-demethylase/0.457
1h50FMNPentaerythritol tetranitrate reductase/0.456
2gv8NDPThiol-specific monooxygenase1.14.130.456
2he5NDPAldo-keto reductase family 1 member C211.1.10.456
2hk9NAPShikimate dehydrogenase (NADP(+))/0.456
2yylFAD4-hydroxyphenylacetate 3-monooxygenase oxygenase component1.14.14.90.456
3oeyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.456
4imoPWZProstaglandin-H2 D-isomerase5.3.99.20.456
4xumIMNPeroxisome proliferator-activated receptor gamma/0.456
4zirANPEnergy-coupling factor transporter ATP-binding protein EcfA23.6.30.456
4zirANPEnergy-coupling factor transporter ATP-binding protein EcfA1/0.456
1dirNADDihydropteridine reductase1.5.1.340.455
1zp9ATPRIO-type serine/threonine-protein kinase Rio12.7.11.10.455
1zthADPRIO-type serine/threonine-protein kinase Rio12.7.11.10.455
2ww4ADP4-diphosphocytidyl-2-C-methyl-D-erythritol kinase2.7.1.1480.455
2znpK55Peroxisome proliferator-activated receptor delta/0.455
3vt7VDXVitamin D3 receptor/0.455
3wrhCAMCamphor 5-monooxygenase1.14.15.10.455
4xugF9FTryptophan synthase alpha chain/0.455
4xznNAPAldo-keto reductase family 1 member B101.1.10.455
1tdrMTXDihydrofolate reductase1.5.1.30.454
1y9dTPPPyruvate oxidase1.2.3.30.454
2ahrNAPPyrroline-5-carboxylate reductase/0.454
2i7pACOPantothenate kinase 32.7.1.330.454
2owkSAHDiphthine synthase/0.454
2y9qANPMitogen-activated protein kinase 12.7.11.240.454
3otbDGTProbable tRNA(His) guanylyltransferase2.7.7.790.454
4fw8NAI3-oxoacyl-(Acyl-carrier-protein) reductase/0.454
4r21STRCytochrome P450 family 17 polypeptide 2/0.454
4xguADPPutative pachytene checkpoint protein 2/0.454
1f8fNADBenzyl alcohol dehydrogenase/0.453
2bpw1INGag-Pol polyprotein3.4.23.160.453
2g5cNADPrephenate dehydrogenase/0.453
2gmjFADElectron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial1.5.5.10.453
3cxw7CPSerine/threonine-protein kinase pim-12.7.11.10.453
3h3r14HCollagen type IV alpha-3-binding protein/0.453
4bfxZVXPantothenate kinase2.7.1.330.453
4jx1CAHCamphor 5-monooxygenase1.14.15.10.453
4q71FADBifunctional protein PutA/0.453
4q72FADBifunctional protein PutA/0.453
4v2gITCTetracycline repressor protein class D/0.453
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.453
1ddrMTXDihydrofolate reductase1.5.1.30.452
1fm7DFVChalcone--flavonone isomerase 15.5.1.60.452
1i5eU5PUracil phosphoribosyltransferase/0.452
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.452
1rneC60Renin3.4.23.150.452
1s5kCOAAminoglycoside N(6')-acetyltransferase type 1/0.452
2rcyNAPPyrroline-5-carboxylate reductase/0.452
3gkaFMNN-ethylmaleimide reductase/0.452
3p67FMNPentaerythritol tetranitrate reductase/0.452
3sp9IL2Peroxisome proliferator-activated receptor delta/0.452
4a802ANMajor pollen allergen Bet v 1-A/0.452
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.452
4dreNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.452
4m9aFDAAcyl-CoA dehydrogenase/0.452
2aqkNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.451
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.451
2dxvSAHDiphthine synthase/0.451
2g1s4IGRenin3.4.23.150.451
2hutSAHDiphthine synthase/0.451
2p2xSAHDiphthine synthase/0.451
2po7CHDFerrochelatase, mitochondrial4.99.1.10.451
3a0tADPSensor histidine kinase/0.451
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.451
3eigMTXDihydrofolate reductase1.5.1.30.451
3g6zA7TRenin3.4.23.150.451
3imgBZ2Pantothenate synthetase6.3.2.10.451
3lpfZ77Beta-glucuronidase3.2.1.310.451
4enhFVXCholesterol 24-hydroxylase/0.451
4yaoFMNNADPH--cytochrome P450 reductase/0.451
1h74ADPHomoserine kinase2.7.1.390.450
1nlmUD1UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase/0.450
1txtCAAHMG-CoA synthase/0.450
2c29NAPDihydroflavonol 4-reductase/0.450
2el0SAHDiphthine synthase/0.450
2gjlFMNNitronate monooxygenase1.13.12.160.450
2hr8SAHDiphthine synthase/0.450
2pncCLUPrimary amine oxidase, liver isozyme/0.450
2pnjCHDFerrochelatase, mitochondrial4.99.1.10.450
2x7hPFNProstaglandin reductase 310.450
2yj5ATPCopper-transporting ATPase/0.450
2yyiFAD4-hydroxyphenylacetate 3-monooxygenase oxygenase component1.14.14.90.450
3a1cACPProbable copper-exporting P-type ATPase A3.6.3.540.450
3a28NADL-2,3-butanediol dehydrogenase1.1.1.760.450
3d4pNADL-lactate dehydrogenase 11.1.1.270.450
3kb1ADPIron-sulfur cluster carrier protein/0.450
4a83DXCMajor pollen allergen Bet v 1-A/0.450
4ej0NAPADP-L-glycero-D-manno-heptose-6-epimerase/0.450
4is3NAD3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 21.17.98.10.450
4jazSTLPeroxisome proliferator-activated receptor gamma/0.450
4kbyC2EStimulator of interferon genes protein/0.450
4lxa1YSBeta-secretase 13.4.23.460.450
4q73FADBifunctional protein PutA/0.450
4rrvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.450
4xj3GTPCyclic GMP-AMP synthase/0.450
5hg0SAMPantothenate synthetase/0.450
1ee9NADMethylenetetrahydrofolate dehydrogenase [NAD(+)]1.5.1.150.449
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.449
1p0fNAPNADP-dependent alcohol dehydrogenase1.1.1.20.449
1x1aSAMC-20 methyltransferase/0.449
2ktdPUCProstaglandin-H2 D-isomerase5.3.99.20.449
3gobHXXDdmC/0.449
3och2MXDihydrofolate reductase1.5.1.30.449
4a87NARMajor pollen allergen Bet v 1-A/0.449
4bfzZVZPantothenate kinase2.7.1.330.449
4hbm0Y7E3 ubiquitin-protein ligase Mdm26.3.20.449
4jicFMNGTN Reductase/0.449
4m55NADUDP-glucuronic acid decarboxylase 14.1.1.350.449
4opiFDAConserved Archaeal protein/0.449
4opuFDAConserved Archaeal protein/0.449
4x5iFOLDihydrofolate reductase1.5.1.30.449
4zowCLMMultidrug transporter MdfA/0.449
5eb5FAD(R)-mandelonitrile lyase 14.1.2.100.449
6cp4CAMCamphor 5-monooxygenase1.14.15.10.449
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.448
1osvCHCBile acid receptor/0.448
1ykdCMPAdenylate cyclase/0.448
1zxmANPDNA topoisomerase 2-alpha5.99.1.30.448
2a7r5GPGMP reductase 2/0.448
2oapANPType II secretion system protein (GspE-2)/0.448
2ojg19AMitogen-activated protein kinase 12.7.11.240.448
2tctCTCTetracycline repressor protein class D/0.448
2znq401Peroxisome proliferator-activated receptor delta/0.448
3cid318Beta-secretase 13.4.23.460.448
3r9iADPSeptum site-determining protein MinD/0.448
3toh079Gag-Pol polyprotein2.7.7.490.448
3uoyFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.448
3wrjCAMCamphor 5-monooxygenase1.14.15.10.448
4trnNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.448
4zjuNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.448
5hs1VORLanosterol 14-alpha demethylase/0.448
1ju2FAD(R)-mandelonitrile lyase 24.1.2.100.447
1mj9COAHistone acetyltransferase ESA1/0.447
2c54NADGDP-mannose 3,5-epimerase5.1.3.180.447
2fy4COACholine O-acetyltransferase2.3.1.60.447
2gtk208Peroxisome proliferator-activated receptor gamma/0.447
2iko7IGRenin3.4.23.150.447
2v13C40Renin3.4.23.150.447
3fwgCAMCamphor 5-monooxygenase1.14.15.10.447
3ig6438Urokinase-type plasminogen activator3.4.21.730.447
3nugNADPyridoxal 4-dehydrogenase1.1.1.1070.447
4bgiI4IEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.447
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.447
4dbzNDPPutative ketoacyl reductase1.3.10.447
4la7A1OAbscisic acid receptor PYL2/0.447
4x7wMVIMycinamicin III 3''-O-methyltransferase2.1.1.2370.447
4xcvNDPProbable hydroxyacid dehydrogenase protein/0.447
4z5wILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.447
1cf3FADGlucose oxidase1.1.3.40.446
1dyhDZFDihydrofolate reductase1.5.1.30.446
1fm4DXCMajor pollen allergen Bet v 1-L/0.446
1fmlRTLRetinol dehydratase/0.446
1fx9MJIPhospholipase A2, major isoenzyme3.1.1.40.446
1ha3MAUElongation factor Tu-A/0.446
1i7gAZ2Peroxisome proliferator-activated receptor alpha/0.446
1i7iAZ2Peroxisome proliferator-activated receptor gamma/0.446
2gmhFADElectron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial1.5.5.10.446
2qs4LY5Glutamate receptor ionotropic, kainate 1/0.446
2zbaZBATrichothecene 3-O-acetyltransferase/0.446
2znoS44Peroxisome proliferator-activated receptor gamma/0.446
3adaNADSubunit alpha of sarocosine oxidase/0.446
3akn11DFatty acid-binding protein, intestinal/0.446
3b70NAPEnoyl reductase LovC10.446
3mk6ACOPantothenate kinase 32.7.1.330.446
3oagLPQRenin3.4.23.150.446
3of2NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.446
3uzwNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.446
3v2uATPProtein GAL3/0.446
3w8eNAD3-hydroxybutyrate dehydrogenase/0.446
4a6cQG9Gag-Pol polyprotein3.4.23.160.446
4djaFAD(6-4) photolyase/0.446
4g6gFADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.446
4g74FADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.446
4mkhAP5Adenylate kinase/0.446
4nd3NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.446
4wda2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.446
4xsvC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.446
4yryFADGlutamate synthase, beta subunit/0.446
4z63ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.446
5ah5LSSLeucine--tRNA ligase/0.446
1c6yMK1Protease/0.445
1c9k5GPBifunctional adenosylcobalamin biosynthesis protein CobU/0.445
1fmjRTLRetinol dehydratase/0.445
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.445
1t2cNAIL-lactate dehydrogenase1.1.1.270.445
1xs7MMIBeta-secretase 13.4.23.460.445
2cjfRP43-dehydroquinate dehydratase4.2.1.100.445
2ejzSAHDiphthine synthase/0.445
2q8sL92Peroxisome proliferator-activated receptor gamma/0.445
2vbdV10Isopenicillin N synthase1.21.3.10.445
3ai2NDPNADPH-sorbose reductase/0.445
3b2sB2STrichothecene 3-O-acetyltransferase/0.445
3g49NAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.445
3gfbNADL-threonine 3-dehydrogenase/0.445
3h3t16HCollagen type IV alpha-3-binding protein/0.445
3vdqNAD3-hydroxybutyrate dehydrogenase/0.445
4i6aHMG3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.880.445
5a0yCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.445
5a0yCOMMethyl-coenzyme M reductase I subunit beta2.8.4.10.445
1e3eNAIAlcohol dehydrogenase 41.1.1.10.444
1l3iSAHProbable cobalt-precorrin-6B C(15)-methyltransferase (decarboxylating)/0.444
1q19SSCCarbapenam-3-carboxylate synthase6.3.3.60.444
1qlhNADAlcohol dehydrogenase E chain1.1.1.10.444
1zeoC01Peroxisome proliferator-activated receptor gamma/0.444
2c1bCQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.444
2cbrA80Cellular retinoic acid-binding protein 1/0.444
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.444
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.444
2g1o2IGRenin3.4.23.150.444
2g226IGRenin3.4.23.150.444
2ivpATPtRNA N6-adenosine threonylcarbamoyltransferase/0.444
2ojtUBAGlutamate receptor ionotropic, kainate 1/0.444
2vwqNAPGlucose 1-dehydrogenase/0.444
2y8qADP5'-AMP-activated protein kinase subunit gamma-1/0.444
3a3yOBNSodium/potassium-transporting ATPase subunit alpha/0.444
3bgxMEFThymidylate synthase/0.444
3fwfCAMCamphor 5-monooxygenase1.14.15.10.444
3iqhTYR_ASP_ILECysteine synthase2.5.1.470.444
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.444
3nr4PYVAbscisic acid receptor PYL2/0.444
3w2eNADNADH-cytochrome b5 reductase 31.6.2.20.444
4ambDUDPutative glycosyl transferase/0.444
4bbyFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.444
4cd2FOLDihydrofolate reductase1.5.1.30.444
4e2dFMNDehydrogenase/0.444
4eqwCOACoenzyme A disulfide reductase/0.444
4ipw1G7Mycocyclosin synthase1.14.21.90.444
4nmbFADBifunctional protein PutA/0.444
4qxp1YEStimulator of interferon genes protein/0.444
4yqfGDPSeptin-9/0.444
1a50FIPTryptophan synthase alpha chain/0.443
1iidNHMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.443
1m78NDPDihydrofolate reductase1.5.1.30.443
1rc4DDFDihydrofolate reductase1.5.1.30.443
1rfuADPPyridoxal kinase2.7.1.350.443
2cgv3B3Serine/threonine-protein kinase Chk12.7.11.10.443
2dftADPShikimate kinase2.7.1.710.443
2e8rSAHDiphthine synthase/0.443
2fzwNADAlcohol dehydrogenase class-31.1.1.10.443
2q2vNADBeta-D-hydroxybutyrate dehydrogenase/0.443
3eljGS7Mitogen-activated protein kinase 82.7.11.240.443
3fwjCAMCamphor 5-monooxygenase1.14.15.10.443
3g72A6TRenin3.4.23.150.443
3hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.443
3il1B5DGlutamate receptor 2/0.443
3imeBZ2Pantothenate synthetase6.3.2.10.443
3iqiASN_GLU_ASN_ILECysteine synthase2.5.1.470.443
3t3c017Gag-Pol polyprotein3.4.23.160.443
3tifADPUncharacterized ABC transporter ATP-binding protein MJ0796/0.443
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.443
4hp8NAP2-deoxy-D-gluconate 3-dehydrogenase/0.443
4nwzFADFAD-dependent pyridine nucleotide-disulfide oxidoreductase/0.443
4qi5FADCellobiose dehydrogenase/0.443
4xuhSFIPeroxisome proliferator-activated receptor gamma/0.443
5k5zANPUncharacterized protein/0.443
1ay0TPPTransketolase 12.2.1.10.442
1bil0IURenin3.4.23.150.442
1dr2TAPDihydrofolate reductase1.5.1.30.442
1orkATCTetracycline repressor protein class D/0.442
1pqc444Oxysterols receptor LXR-beta/0.442
1qyw5SDEstradiol 17-beta-dehydrogenase 11.1.1.620.442
1u8vFAD4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase/0.442
1umaIN2Prothrombin3.4.21.50.442
1yb5NAPQuinone oxidoreductase1.6.5.50.442
2c3qGTXGlutathione S-transferase theta-12.5.1.180.442
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.442
2e1mFADL-glutamate oxidase/0.442
2ebaFADPutative glutaryl-CoA dehydrogenase/0.442
2g263LGRenin3.4.23.150.442
2iqgF2IBeta-secretase 13.4.23.460.442
2v5aLZLBiotin carboxylase6.3.4.140.442
2vbpVB1Isopenicillin N synthase1.21.3.10.442
2z4sADPChromosomal replication initiator protein DnaA/0.442
3bhiNAPCarbonyl reductase [NADPH] 11.1.1.1840.442
3bi2FADPolyamine oxidase FMS1/0.442
3flkNAITartrate dehydrogenase/decarboxylase1.1.1.930.442
3hl0NADMaleylacetate reductase/0.442
3oetNADErythronate-4-phosphate dehydrogenase/0.442
3qt62P0Mevalonate diphosphate decarboxylase/0.442
3swqEPUUDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.442
3u33FADPutative acyl-CoA dehydrogenase AidB1.3.990.442
3u9fCLMChloramphenicol acetyltransferase2.3.1.280.442
3vmmP0DAlanine--anticapsin ligase/0.442
4e5pNADPhosphonate dehydrogenase1.20.1.10.442
4eagATP5'-AMP-activated protein kinase subunit gamma-1/0.442
4f32N323-oxoacyl-[acyl-carrier-protein] synthase 2/0.442
4fhd0TTSpore photoproduct lyase/0.442
4g6hNAIRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.442
4ge70K5Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.442
4jq9FADDihydrolipoyl dehydrogenase/0.442
4ktl1CQCytochrome P450/0.442
4nieNBHNuclear receptor ROR-gamma/0.442
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.442
1dhfFOLDihydrofolate reductase1.5.1.30.441
1eioGCHGastrotropin/0.441
1g1aNADdTDP-glucose 4,6-dehydratase/0.441
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.441
1j49NADD-lactate dehydrogenase1.1.1.280.441
1nvtNAPShikimate dehydrogenase (NADP(+))/0.441
1pjcNADAlanine dehydrogenase/0.441
1z7yAA5Cysteine synthase 12.5.1.470.441
2dhfDZFDihydrofolate reductase1.5.1.30.441
2en5SAHDiphthine synthase/0.441
2hunNAD336aa long hypothetical dTDP-glucose 4,6-dehydratase/0.441
2iodMYCDihydroflavonol 4-reductase1.1.1.2190.441
2om9AJAPeroxisome proliferator-activated receptor gamma/0.441
2owuSAHDiphthine synthase/0.441
2q59240Peroxisome proliferator-activated receptor gamma/0.441
2uxpCLMHTH-type transcriptional regulator TtgR/0.441
2v16C47Renin3.4.23.150.441
2vprTDCTetracycline repressor protein class H/0.441
3dghFADThioredoxin reductase 1, mitochondrial1.8.1.90.441
3gb4D3MDdmC/0.441
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.441
3lzs017Gag-Pol polyprotein3.4.23.160.441
3qv1NADGlyceraldehyde-3-phosphate dehydrogenase GAPA1, chloroplastic1.2.1.130.441
3ruhNADUDP-N-acetylglucosamine 4-epimerase/0.441
3vvpBNUUncharacterized protein/0.441
4briUNPEctonucleoside triphosphate diphosphohydrolase I/0.441
4ejmNAPPutative zinc-binding dehydrogenase/0.441
4frkDWDBeta-secretase 13.4.23.460.441
4h6rFDAProline dehydrogenase/0.441
4ktoFADPutative isovaleryl-CoA dehydrogenase protein/0.441
4r20AERCytochrome P450 family 17 polypeptide 2/0.441
4tuvCPZCytochrome P450 1191.140.441
4uwmFMN3,6-diketocamphane 1,6 monooxygenase1.14.130.441
3sn6P0GBeta-2 adrenergic receptor/0.441
1mjbACOHistone acetyltransferase ESA1/0.440
1nzdUPGDNA beta-glucosyltransferase/0.440
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.440
2cv1ATPGlutamate--tRNA ligase6.1.1.170.440
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.440
2feuCAMCamphor 5-monooxygenase1.14.15.10.440
2fw3BUICarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.440
2fznFADBifunctional protein PutA1.5.5.20.440
2irzI02Beta-secretase 13.4.23.460.440
2nnlNAPDihydroflavonol 4-reductase1.1.1.2190.440
2ou2ACOHistone acetyltransferase KAT5/0.440
2y3sTIRTamL/0.440
3fhxPLPPyridoxal kinase2.7.1.350.440
3fwiCAMCamphor 5-monooxygenase1.14.15.10.440
3tvuB37Acetyl-CoA carboxylase/0.440
3zhsTD6Multifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.440
3ziaADPATP synthase subunit beta, mitochondrial3.6.3.140.440
4a862ANMajor pollen allergen Bet v 1-A/0.440
4ead0NPThymidine phosphorylase2.4.2.40.440
4f4dCHDFerrochelatase, mitochondrial4.99.1.10.440
4h3qANPMitogen-activated protein kinase 12.7.11.240.440
4kgnSAHtRNA (cytidine(34)-2'-O)-methyltransferase/0.440
4ocvANPAminoglycoside phosphotransferase/0.440