sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2rg6 | 287 | Mitogen-activated protein kinase 14 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2rg6 | 287 | Mitogen-activated protein kinase 14 | / | 1.000 | |
| 2bal | PQA | Mitogen-activated protein kinase 14 | / | 0.608 | |
| 3iph | G11 | Mitogen-activated protein kinase 14 | / | 0.605 | |
| 3fkl | FKL | Mitogen-activated protein kinase 14 | / | 0.603 | |
| 2rg5 | 279 | Mitogen-activated protein kinase 14 | / | 0.601 | |
| 3fln | 3FN | Mitogen-activated protein kinase 14 | / | 0.590 | |
| 3nww | 3NW | Mitogen-activated protein kinase 14 | / | 0.588 | |
| 3mpt | 1GK | Mitogen-activated protein kinase 14 | / | 0.587 | |
| 3dt1 | P40 | Mitogen-activated protein kinase 14 | / | 0.586 | |
| 4aa5 | NQB | Mitogen-activated protein kinase 14 | / | 0.586 | |
| 4aac | AAV | Mitogen-activated protein kinase 14 | / | 0.583 | |
| 3ocg | OCG | Mitogen-activated protein kinase 14 | / | 0.578 | |
| 3fsk | RO6 | Mitogen-activated protein kinase 14 | / | 0.577 | |
| 3flz | FLZ | Mitogen-activated protein kinase 14 | / | 0.576 | |
| 3mvm | 39P | Mitogen-activated protein kinase 14 | / | 0.569 | |
| 4kin | 1M8 | Mitogen-activated protein kinase 14 | / | 0.569 | |
| 4kip | 1R9 | Mitogen-activated protein kinase 14 | / | 0.563 | |
| 3l8x | N4D | Mitogen-activated protein kinase 14 | / | 0.556 | |
| 3fi4 | FI4 | Mitogen-activated protein kinase 14 | / | 0.554 | |
| 2qd9 | LGF | Mitogen-activated protein kinase 14 | / | 0.551 | |
| 3mvl | 38P | Mitogen-activated protein kinase 14 | / | 0.550 | |
| 4kiq | 1RA | Mitogen-activated protein kinase 14 | / | 0.550 | |
| 3fmh | 533 | Mitogen-activated protein kinase 14 | / | 0.548 | |
| 3s4q | NK0 | Mitogen-activated protein kinase 14 | / | 0.542 | |
| 4aa4 | QC0 | Mitogen-activated protein kinase 14 | / | 0.542 | |
| 3fly | FLY | Mitogen-activated protein kinase 14 | / | 0.538 | |
| 3flw | FLW | Mitogen-activated protein kinase 14 | / | 0.532 | |
| 3gfe | P37 | Mitogen-activated protein kinase 14 | / | 0.531 | |
| 3hl7 | I47 | Mitogen-activated protein kinase 14 | / | 0.529 | |
| 3bv2 | P38 | Mitogen-activated protein kinase 14 | / | 0.524 | |
| 3fmk | FMK | Mitogen-activated protein kinase 14 | / | 0.523 | |
| 4lop | SB4 | Mitogen-activated protein kinase 14 | / | 0.518 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.511 | |
| 3itz | P66 | Mitogen-activated protein kinase 14 | / | 0.507 | |
| 1zz2 | B11 | Mitogen-activated protein kinase 14 | / | 0.506 | |
| 2ghl | LIB | Mitogen-activated protein kinase 14 | / | 0.504 | |
| 2zb0 | GK3 | Mitogen-activated protein kinase 14 | / | 0.504 | |
| 2gtn | LIE | Mitogen-activated protein kinase 14 | / | 0.503 | |
| 3d7z | GK5 | Mitogen-activated protein kinase 14 | / | 0.503 | |
| 4eh6 | 0ON | Mitogen-activated protein kinase 14 | / | 0.503 | |
| 3bv3 | P39 | Mitogen-activated protein kinase 14 | / | 0.502 | |
| 1ywn | LIF | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.501 | |
| 3uvq | FS8 | Mitogen-activated protein kinase 14 | / | 0.501 | |
| 3b2w | 9NH | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.499 | |
| 3u8w | 09J | Mitogen-activated protein kinase 14 | / | 0.499 | |
| 3b8r | 887 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.494 | |
| 3hvc | GG5 | Mitogen-activated protein kinase 14 | / | 0.494 | |
| 4loo | SB4 | Mitogen-activated protein kinase 14 | / | 0.494 | |
| 2oiq | STI | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.493 | |
| 2pl0 | STI | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.493 | |
| 2zb1 | GK4 | Mitogen-activated protein kinase 14 | / | 0.493 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.493 | |
| 1y57 | MPZ | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.492 | |
| 1ouy | 094 | Mitogen-activated protein kinase 14 | / | 0.491 | |
| 3uib | SB2 | Putative mitogen-activated protein kinase | / | 0.487 | |
| 3uyt | 0CK | Casein kinase I isoform delta | 2.7.11.1 | 0.487 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.486 | |
| 3ule | C69 | Actin-related protein 3 | / | 0.485 | |
| 3uvp | 048 | Mitogen-activated protein kinase 14 | / | 0.485 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.483 | |
| 2gfs | PQB | Mitogen-activated protein kinase 14 | / | 0.482 | |
| 2x6t | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.482 | |
| 3v8w | 0G2 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.482 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.482 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.481 | |
| 4xq9 | NAD | Homospermidine synthase | 2.5.1.44 | 0.481 | |
| 4loq | SB4 | Mitogen-activated protein kinase 14 | / | 0.480 | |
| 4ynt | FDA | Glucose oxidase, putative | / | 0.480 | |
| 1qpe | PP2 | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.479 | |
| 3fmn | 530 | Mitogen-activated protein kinase 14 | / | 0.479 | |
| 4id7 | 1G0 | Activated CDC42 kinase 1 | / | 0.479 | |
| 1iep | STI | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.478 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.478 | |
| 4kzo | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.478 | |
| 1e6w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.477 | |
| 2p2h | 994 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.477 | |
| 2vyn | NAD | Glyceraldehyde-3-phosphate dehydrogenase A | / | 0.477 | |
| 4bkj | STI | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.476 | |
| 4i23 | 1C9 | Epidermal growth factor receptor | 2.7.10.1 | 0.476 | |
| 2og8 | 1N8 | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.475 | |
| 3kjr | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.475 | |
| 3t2z | FAD | Sulfide-quinone reductase | / | 0.475 | |
| 4xrg | NAD | Homospermidine synthase | 2.5.1.44 | 0.475 | |
| 2e9u | A25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.474 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.474 | |
| 3iw5 | DF3 | Mitogen-activated protein kinase 14 | / | 0.474 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.474 | |
| 1rw8 | 580 | TGF-beta receptor type-1 | 2.7.11.30 | 0.473 | |
| 2hfp | NSI | Peroxisome proliferator-activated receptor gamma | / | 0.473 | |
| 3bgb | LJG | Gag-Pol polyprotein | 3.4.23.16 | 0.473 | |
| 3ggg | NAD | Prephenate dehydrogenase | / | 0.473 | |
| 3hll | I45 | Mitogen-activated protein kinase 14 | / | 0.473 | |
| 4jvf | 17X | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.473 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.473 | |
| 3hja | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.472 | |
| 3i59 | N6R | CRP-like cAMP-activated global transcriptional regulator | / | 0.472 | |
| 3lfa | 1N1 | Mitogen-activated protein kinase 14 | / | 0.472 | |
| 3opd | HIE | Heat shock protein 83 | / | 0.472 | |
| 4ji9 | 1M3 | Tyrosine-protein kinase JAK2 | / | 0.472 | |
| 2gek | GDP | Phosphatidyl-myo-inositol mannosyltransferase | 2.4.1.57 | 0.471 | |
| 2yyi | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.471 | |
| 3gc9 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.471 | |
| 4at0 | FAD | Possible succinate dehydrogenase | / | 0.471 | |
| 4fuy | EK2 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.471 | |
| 1vjy | 460 | TGF-beta receptor type-1 | 2.7.11.30 | 0.470 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.470 | |
| 2iml | FMN | Uncharacterized protein | / | 0.470 | |
| 3t14 | FAD | Sulfide-quinone reductase | / | 0.470 | |
| 4eh7 | 0OO | Mitogen-activated protein kinase 14 | / | 0.470 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.469 | |
| 5cvf | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.469 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.468 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.468 | |
| 2vwx | 7X4 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.468 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.468 | |
| 4jin | 1L7 | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.468 | |
| 4p8r | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.468 | |
| 1gqt | ACP | Ribokinase | / | 0.467 | |
| 3ac2 | KSE | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.467 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.467 | |
| 3bbt | FMM | Receptor tyrosine-protein kinase erbB-4 | 2.7.10.1 | 0.467 | |
| 4ftk | H9K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.467 | |
| 1adf | TAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.466 | |
| 1ot7 | IU5 | Bile acid receptor | / | 0.466 | |
| 1szm | BI4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.466 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.466 | |
| 2ewm | NAD | (S)-1-Phenylethanol dehydrogenase | 1.1.1.311 | 0.466 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.466 | |
| 2y6o | 1N1 | Ephrin type-A receptor 4 | 2.7.10.1 | 0.466 | |
| 3cuk | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.466 | |
| 3dmt | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.466 | |
| 4a87 | NAR | Major pollen allergen Bet v 1-A | / | 0.466 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.466 | |
| 5itz | LOC | Tubulin beta-2B chain | / | 0.466 | |
| 1cx4 | CMP | cAMP-dependent protein kinase type II-beta regulatory subunit | / | 0.465 | |
| 1yba | NAD | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.465 | |
| 2ivp | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.465 | |
| 3c7q | XIN | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.465 | |
| 3gu8 | 3GU | Death-associated protein kinase 1 | 2.7.11.1 | 0.465 | |
| 3tvu | B37 | Acetyl-CoA carboxylase | / | 0.465 | |
| 3uku | C69 | Actin-related protein 3 | / | 0.465 | |
| 4xye | NAD | Formate dehydrogenase | / | 0.465 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.465 | |
| 1d3g | BRE | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.464 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.464 | |
| 1g4t | FTP | Thiamine-phosphate synthase | / | 0.464 | |
| 2gtm | LID | Mitogen-activated protein kinase 14 | / | 0.464 | |
| 2wdz | NAD | Galactitol dehydrogenase | / | 0.464 | |
| 4bdh | WVI | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.464 | |
| 4fc7 | NAP | Peroxisomal 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.464 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.464 | |
| 1bxo | PP7 | Penicillopepsin-1 | 3.4.23.20 | 0.463 | |
| 1ie3 | NAD | Malate dehydrogenase | / | 0.463 | |
| 1k6c | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.463 | |
| 2itw | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.463 | |
| 2ozu | ACO | Histone acetyltransferase KAT6A | / | 0.463 | |
| 3sz0 | FAD | Sulfide-quinone reductase | / | 0.463 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.463 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.463 | |
| 1gd1 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.462 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.462 | |
| 1kr2 | TAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.462 | |
| 1qxs | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.462 | |
| 2acx | ANP | G protein-coupled receptor kinase 6 | 2.7.11.16 | 0.462 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.462 | |
| 3c0i | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.462 | |
| 3w0g | W07 | Vitamin D3 receptor | / | 0.462 | |
| 3zuy | TCH | Transporter | / | 0.462 | |
| 4eh3 | NAR | Mitogen-activated protein kinase 14 | / | 0.462 | |
| 4qo9 | 627 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.462 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.462 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.461 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.461 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 3ids | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.461 | |
| 3r3s | NAD | Putative oxidoreductase | / | 0.461 | |
| 3roc | 29A | Mitogen-activated protein kinase 14 | / | 0.461 | |
| 3w0j | T08 | Vitamin D3 receptor | / | 0.461 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.461 | |
| 4ku5 | DCC | 3-oxoacyl-[ACP] synthase III | / | 0.461 | |
| 1o0s | NAI | NAD-dependent malic enzyme, mitochondrial | 1.1.1.38 | 0.460 | |
| 2itx | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.460 | |
| 2ivn | ANP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.460 | |
| 2xsz | ATP | RuvB-like 2 | 3.6.4.12 | 0.460 | |
| 2y3r | TRK | TamL | / | 0.460 | |
| 3gbu | ATP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.460 | |
| 4er6 | AW2 | Histone-lysine N-methyltransferase, H3 lysine-79 specific | 2.1.1.43 | 0.460 | |
| 4otw | DB8 | Receptor tyrosine-protein kinase erbB-3 | 2.7.10.1 | 0.460 | |
| 4xqc | NAD | Homospermidine synthase | 2.5.1.44 | 0.460 | |
| 1i7g | AZ2 | Peroxisome proliferator-activated receptor alpha | / | 0.459 | |
| 1ipe | NDP | Tropinone reductase 2 | 1.1.1.236 | 0.459 | |
| 1npt | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.459 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.459 | |
| 1uuo | BRF | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.459 | |
| 1y5r | C0R | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.459 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.459 | |
| 2igo | FAD | Pyranose 2-oxidase | / | 0.459 | |
| 2y3s | TIR | TamL | / | 0.459 | |
| 3cbl | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.459 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.459 | |
| 3e5r | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1, cytosolic | 1.2.1.12 | 0.459 | |
| 3ekp | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.459 | |
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.459 | |
| 3vfq | AR6 | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.459 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.459 | |
| 4bf2 | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.459 | |
| 4jr3 | KJR | Epidermal growth factor receptor | 2.7.10.1 | 0.459 | |
| 5a3b | APR | SIR2 family protein | / | 0.459 | |
| 5bsg | NAP | Pyrroline-5-carboxylate reductase | / | 0.459 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 1mg5 | NAI | Alcohol dehydrogenase | 1.1.1.1 | 0.458 | |
| 1nqa | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.458 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.458 | |
| 3ac3 | KSH | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.458 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.458 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.458 | |
| 3ggp | NAD | Prephenate dehydrogenase | / | 0.458 | |
| 3jyn | NDP | Quinone oxidoreductase | / | 0.458 | |
| 3lsh | FAD | Pyranose 2-oxidase | / | 0.458 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.458 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.458 | |
| 3zep | 1NX | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.458 | |
| 4e5y | NDP | GDP-L-fucose synthase | 1.1.1.271 | 0.458 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.457 | |
| 1lso | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.457 | |
| 1osv | CHC | Bile acid receptor | / | 0.457 | |
| 1ykf | NAP | NADP-dependent isopropanol dehydrogenase | 1.1.1.80 | 0.457 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.457 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.457 | |
| 3ds6 | A17 | Mitogen-activated protein kinase 14 | / | 0.457 | |
| 3hdm | MMG | Serine/threonine-protein kinase Sgk1 | 2.7.11.1 | 0.457 | |
| 3uxy | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.457 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 4jq8 | KJ8 | Epidermal growth factor receptor | 2.7.10.1 | 0.457 | |
| 4o0r | X4Z | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.457 | |
| 1c70 | L75 | Protease | / | 0.456 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.456 | |
| 1lsj | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.456 | |
| 1nfr | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.456 | |
| 1qvn | FRI | Interleukin-2 | / | 0.456 | |
| 2a5u | QYT | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.456 | |
| 2c0i | L1G | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.456 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.456 | |
| 2p9e | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.456 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.456 | |
| 2vx0 | 7X7 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.456 | |
| 2xk9 | XK9 | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.456 | |
| 2xvd | AS6 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.456 | |
| 3b8q | 900 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.456 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.456 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 3syi | FAD | Sulfide-quinone reductase | / | 0.456 | |
| 4dgg | I76 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.456 | |
| 4g1d | 0VK | Vitamin D3 receptor A | / | 0.456 | |
| 4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.456 | |
| 4xgi | NAD | Glutamate dehydrogenase | / | 0.456 | |
| 5jsc | FAD | Putative acyl-CoA dehydrogenase | / | 0.456 | |
| 1h73 | ANP | Homoserine kinase | 2.7.1.39 | 0.455 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.455 | |
| 1u2g | APR | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.455 | |
| 1zyj | BI5 | Mitogen-activated protein kinase 14 | / | 0.455 | |
| 2g5c | NAD | Prephenate dehydrogenase | / | 0.455 | |
| 2qo5 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.455 | |
| 2wmu | ZYU | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.455 | |
| 2y3r | TIR | TamL | / | 0.455 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.455 | |
| 3czr | 3CZ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.455 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.455 | |
| 4agw | NG7 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.455 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.455 | |
| 4fn4 | NAD | Short chain dehydrogenase | / | 0.455 | |
| 5eyp | LOC | Tubulin beta chain | / | 0.455 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.454 | |
| 1qcf | PP1 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.454 | |
| 1zp9 | ATP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.454 | |
| 2itv | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.454 | |
| 2xyu | Q9G | Ephrin type-A receptor 4 | 2.7.10.1 | 0.454 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.454 | |
| 3bts | NAD | Galactose/lactose metabolism regulatory protein GAL80 | / | 0.454 | |
| 3cvu | FAD | RE11660p | / | 0.454 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.454 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.454 | |
| 4kl9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 4nwz | FAD | FAD-dependent pyridine nucleotide-disulfide oxidoreductase | / | 0.454 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.454 | |
| 1c1d | NAI | Phenylalanine dehydrogenase | / | 0.453 | |
| 2ahr | NAP | Pyrroline-5-carboxylate reductase | / | 0.453 | |
| 2brh | DFW | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.453 | |
| 2gsd | NAD | Formate dehydrogenase | / | 0.453 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.453 | |
| 2o4r | VD5 | Vitamin D3 receptor | / | 0.453 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.453 | |
| 3dxm | N24 | Actin-related protein 3 | / | 0.453 | |
| 3r5y | F42 | Uncharacterized protein | / | 0.453 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.453 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.453 | |
| 4b8z | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.453 | |
| 4kto | FAD | Putative isovaleryl-CoA dehydrogenase protein | / | 0.453 | |
| 4mdh | NAD | Malate dehydrogenase, cytoplasmic | 1.1.1.37 | 0.453 | |
| 4nie | NBH | Nuclear receptor ROR-gamma | / | 0.453 | |
| 4plp | NAD | Homospermidine synthase | 2.5.1.44 | 0.453 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.453 | |
| 5eai | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.453 | |
| 1bw9 | NAD | Phenylalanine dehydrogenase | / | 0.452 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.452 | |
| 1pjk | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.452 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.452 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.452 | |
| 3bbr | BHY | Glutamate receptor 2 | / | 0.452 | |
| 3cif | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.452 | |
| 3clb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.452 | |
| 3cmc | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.452 | |
| 3hp5 | 52P | Mitogen-activated protein kinase 14 | / | 0.452 | |
| 3ksd | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1 | / | 0.452 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.452 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.452 | |
| 2gej | GDD | Phosphatidyl-myo-inositol mannosyltransferase | 2.4.1.57 | 0.451 | |
| 2j5x | GSP | ADP-ribosylation factor 6 | / | 0.451 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.451 | |
| 2q4w | FAD | Cytokinin dehydrogenase 7 | 1.5.99.12 | 0.451 | |
| 2qn3 | F55 | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.451 | |
| 2rew | REW | Peroxisome proliferator-activated receptor alpha | / | 0.451 | |
| 2yn8 | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.451 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.451 | |
| 3n7u | NAD | Formate dehydrogenase, chloroplastic/mitochondrial | / | 0.451 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.451 | |
| 3vs4 | VSF | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.451 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.451 | |
| 4bb4 | 32W | Ephrin type-B receptor 4 | 2.7.10.1 | 0.451 | |
| 4cec | 2SS | Integrase | / | 0.451 | |
| 4irn | FAD | AnaB | / | 0.451 | |
| 4ki8 | ADP | 60 kDa chaperonin | / | 0.451 | |
| 5eb5 | FAD | (R)-mandelonitrile lyase 1 | 4.1.2.10 | 0.451 | |
| 1yw2 | PGJ | Mitogen-activated protein kinase 14 | / | 0.450 | |
| 2cgw | 3C3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.450 | |
| 2g37 | FAD | Proline dehydrogenase | / | 0.450 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 2pa3 | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.450 | |
| 2yir | YIR | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.450 | |
| 2zla | VDB | Vitamin D3 receptor | / | 0.450 | |
| 3lfe | Z84 | Mitogen-activated protein kinase 14 | / | 0.450 | |
| 3pgq | GY3 | Acetyl-CoA carboxylase | / | 0.450 | |
| 3sp6 | IL2 | Peroxisome proliferator-activated receptor alpha | / | 0.450 | |
| 3tqa | NDP | Dihydrofolate reductase | / | 0.450 | |
| 3tz3 | B36 | Acetyl-CoA carboxylase | / | 0.450 | |
| 3vt4 | 5YI | Vitamin D3 receptor | / | 0.450 | |
| 4b8w | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.450 | |
| 4c8b | 0LI | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.450 | |
| 4g2f | C07 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.450 | |
| 4h4u | NDP | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.450 | |
| 4jq7 | KJQ | Epidermal growth factor receptor | 2.7.10.1 | 0.450 | |
| 4lb2 | DM5 | Serum albumin | / | 0.450 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.450 | |
| 5e8w | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.450 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 1dg8 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1k7l | 544 | Peroxisome proliferator-activated receptor alpha | / | 0.449 | |
| 1ywr | LI9 | Mitogen-activated protein kinase 14 | / | 0.449 | |
| 2c0o | L2G | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.449 | |
| 2dq7 | STU | Tyrosine-protein kinase Fyn | 2.7.10.2 | 0.449 | |
| 2om9 | AJA | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 2p9c | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.449 | |
| 2wq7 | FAD | RE11660p | / | 0.449 | |
| 2zb3 | NDP | Prostaglandin reductase 2 | 1.3.1.48 | 0.449 | |
| 2zlc | VDX | Vitamin D3 receptor | / | 0.449 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.449 | |
| 3w0i | O11 | Vitamin D3 receptor | / | 0.449 | |
| 3w0q | ANP | Hygromycin-B 4-O-kinase | 2.7.1.163 | 0.449 | |
| 3zt0 | ZT0 | Integrase | / | 0.449 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.449 | |
| 4dja | FAD | (6-4) photolyase | / | 0.449 | |
| 4fj0 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.449 | |
| 4fod | 0UV | ALK tyrosine kinase receptor | 2.7.10.1 | 0.449 | |
| 4hjo | AQ4 | Epidermal growth factor receptor | 2.7.10.1 | 0.449 | |
| 4jvb | 1M0 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.449 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.449 | |
| 4nka | 2K7 | Fibroblast growth factor receptor 1 | / | 0.449 | |
| 5br4 | NAD | Lactaldehyde reductase | 1.1.1.77 | 0.449 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.449 | |
| 1a7k | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.448 | |
| 1gyp | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.448 | |
| 1ml3 | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.448 | |
| 1rrm | APR | Lactaldehyde reductase | 1.1.1.77 | 0.448 | |
| 1trg | CB3 | Thymidylate synthase | / | 0.448 | |
| 2ev9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.448 | |
| 2nua | COA | Succinate--CoA ligase [ADP-forming] subunit alpha | 6.2.1.5 | 0.448 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.448 | |
| 2y05 | NAP | Prostaglandin reductase 1 | / | 0.448 | |
| 3ak4 | NAD | NADH-dependent quinuclidinone reductase | / | 0.448 | |
| 3bhi | NAP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.448 | |
| 3d8v | UD1 | Bifunctional protein GlmU | / | 0.448 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.448 | |
| 3pm9 | FAD | Putative oxidoreductase | / | 0.448 | |
| 3vs1 | VSA | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.448 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 4bgi | I4I | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 4o70 | 1QK | Bromodomain-containing protein 4 | / | 0.448 | |
| 4okn | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.448 | |
| 4uyf | 73B | Bromodomain-containing protein 2 | / | 0.448 | |
| 4z26 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.448 | |
| 5lc1 | NAD | L-threonine 3-dehydrogenase | / | 0.448 | |
| 1b16 | NAQ | Alcohol dehydrogenase | 1.1.1.1 | 0.447 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.447 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.447 | |
| 1dxo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.447 | |
| 1fm6 | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.447 | |
| 1ie9 | VDX | Vitamin D3 receptor | / | 0.447 | |
| 1o8c | NDP | Probable acrylyl-CoA reductase AcuI | 1.3.1.84 | 0.447 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.447 | |
| 1rfv | ADP | Pyridoxal kinase | 2.7.1.35 | 0.447 | |
| 1sby | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.447 | |
| 1wn3 | HXC | Phenylacetic acid degradation protein PaaI | / | 0.447 | |
| 1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.447 | |
| 1yhj | R6C | Pyridoxal kinase | 2.7.1.35 | 0.447 | |
| 1yon | A2R | 2-dehydropantoate 2-reductase | 1.1.1.169 | 0.447 | |
| 2avv | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 2cmj | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.447 | |
| 2f1k | NAP | Prephenate dehydrogenase | / | 0.447 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.447 | |
| 2has | C3O | Vitamin D3 receptor | / | 0.447 | |
| 2pg0 | FAD | Acyl-CoA dehydrogenase | / | 0.447 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 2uxp | CLM | HTH-type transcriptional regulator TtgR | / | 0.447 | |
| 2wq6 | FAD | RE11660p | / | 0.447 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.447 | |
| 2yyl | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.447 | |
| 3a28 | NAD | L-2,3-butanediol dehydrogenase | 1.1.1.76 | 0.447 | |
| 3aty | FMN | Prostaglandin F2a synthase | / | 0.447 | |
| 3el8 | PD5 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.447 | |
| 3s55 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.447 | |
| 3sx2 | NAD | Uncharacterized protein | / | 0.447 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.447 | |
| 4ia2 | BIV | Vitamin D3 receptor A | / | 0.447 | |
| 4mv8 | ACP | Biotin carboxylase | 6.3.4.14 | 0.447 | |
| 4ruo | BIV | Vitamin D3 receptor A | / | 0.447 | |
| 4xum | IMN | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 4xwz | FAD | Fructosyl amine:oxygen oxidoreductase | / | 0.447 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.446 | |
| 1kvk | ATP | Mevalonate kinase | 2.7.1.36 | 0.446 | |
| 1nbo | NAD | Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic | 1.2.1.13 | 0.446 | |
| 1p31 | EPU | UDP-N-acetylmuramate--L-alanine ligase | 6.3.2.8 | 0.446 | |
| 1zth | ADP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.446 | |
| 2c0c | NAP | Prostaglandin reductase 3 | 1 | 0.446 | |
| 2e48 | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.446 | |
| 2gv8 | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.446 | |
| 2nr4 | FMN | Conserved protein | / | 0.446 | |
| 2r0u | M54 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.446 | |
| 2vwz | 7X6 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.446 | |
| 2wmq | ZYQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.446 | |
| 2x8e | X8E | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.446 | |
| 2zva | 1N1 | Tyrosine-protein kinase Lyn | 2.7.10.2 | 0.446 | |
| 3em6 | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 3fko | FKO | Mitogen-activated protein kinase 14 | / | 0.446 | |
| 3gi6 | D78 | Gag-Pol polyprotein | / | 0.446 | |
| 3mpa | SB2 | Mitogen-activated protein kinase 14 | / | 0.446 | |
| 3p6o | ETG | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 3tri | NAP | Pyrroline-5-carboxylate reductase | / | 0.446 | |
| 3tuc | FPW | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.446 | |
| 3u4c | NDP | NADPH-dependent reductase BacG | / | 0.446 | |
| 4a99 | FAD | TetX family tetracycline inactivation enzyme | / | 0.446 | |
| 4f7i | NAD | 3-isopropylmalate dehydrogenase | 1.1.1.85 | 0.446 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.446 | |
| 4r21 | STR | Cytochrome P450 family 17 polypeptide 2 | / | 0.446 | |
| 5ack | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.446 | |
| 5dp2 | NAP | CurF | / | 0.446 | |
| 1agw | SU2 | Fibroblast growth factor receptor 1 | / | 0.445 | |
| 1bxq | PP8 | Penicillopepsin-1 | 3.4.23.20 | 0.445 | |
| 1iy8 | NAD | Levodione reductase | / | 0.445 | |
| 1u8f | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.445 | |
| 2bl4 | NAD | Lactaldehyde reductase | 1.1.1.77 | 0.445 | |
| 2e9n | 76A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.445 | |
| 2itt | AEE | Epidermal growth factor receptor | 2.7.10.1 | 0.445 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.445 | |
| 2vtb | FAD | Cryptochrome DASH, chloroplastic/mitochondrial | / | 0.445 | |
| 2wec | PP5 | Penicillopepsin-1 | 3.4.23.20 | 0.445 | |
| 3fhy | ATP | Pyridoxal kinase | 2.7.1.35 | 0.445 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.445 | |
| 3hub | 469 | Mitogen-activated protein kinase 14 | / | 0.445 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.445 | |
| 3lsm | SFD | Pyranose 2-oxidase | / | 0.445 | |
| 3mwu | BK3 | Calmodulin-domain protein kinase 1, putative | / | 0.445 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 3rj5 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.445 | |
| 3uyl | TYD | Probable NDP-rhamnosyltransferase | / | 0.445 | |
| 4g9k | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.445 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.445 | |
| 4gk4 | L90 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.445 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.445 | |
| 4nxu | ADP | Mitochondrial dynamics protein MID51 | / | 0.445 | |
| 4pd6 | URI | Nucleoside permease | / | 0.445 | |
| 4qi4 | FAD | Cellobiose dehydrogenase | / | 0.445 | |
| 4wkq | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.445 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.444 | |
| 1kt3 | RTL | Retinol-binding protein 4 | / | 0.444 | |
| 1mjb | ACO | Histone acetyltransferase ESA1 | / | 0.444 | |
| 1nq5 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.444 | |
| 1ny3 | ADP | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.444 | |
| 1tqm | ANP | RIO-type serine/threonine-protein kinase Rio2 | 2.7.11.1 | 0.444 | |
| 2a1t | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.444 | |
| 2brn | DF1 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 2fto | CB3 | Thymidylate synthase | / | 0.444 | |
| 2idw | 017 | Protease | / | 0.444 | |
| 2itu | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.444 | |
| 2j83 | BAT | Ulilysin | 3.4.24 | 0.444 | |
| 2onm | ADP | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.444 | |
| 2uxh | QUE | HTH-type transcriptional regulator TtgR | / | 0.444 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.444 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 3bc3 | OPT | Cathepsin L1 | 3.4.22.15 | 0.444 | |
| 3dey | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.444 | |
| 3fls | FLS | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 3hx4 | ANP | Calmodulin-domain protein kinase 1 | / | 0.444 | |
| 3ioc | A5D | Pantothenate synthetase | 6.3.2.1 | 0.444 | |
| 3klm | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.444 | |
| 3kpk | FAD | Sulfide-quinone reductase | / | 0.444 | |
| 3lvf | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1 | / | 0.444 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 3vrt | YS2 | Vitamin D3 receptor | / | 0.444 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.444 | |
| 4h6r | FDA | Proline dehydrogenase | / | 0.444 | |
| 4im0 | 1FV | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.444 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.444 | |
| 4is3 | NAD | 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2 | 1.17.98.1 | 0.444 | |
| 5a3c | NAD | SIR2 family protein | / | 0.444 | |
| 5hes | 032 | Mitogen-activated protein kinase kinase kinase 20 | 2.7.11.25 | 0.444 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.443 | |
| 1dss | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.443 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1ma0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.443 | |
| 1me7 | MOA | Inosine-5'-monophosphate dehydrogenase | / | 0.443 | |
| 1ouk | 084 | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 1ygk | RRC | Pyridoxal kinase | 2.7.1.35 | 0.443 | |
| 2f2c | AP9 | Cyclin-dependent kinase 6 | 2.7.11.22 | 0.443 | |
| 2fy4 | COA | Choline O-acetyltransferase | 2.3.1.6 | 0.443 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.443 | |
| 2i0d | MUT | Protease | / | 0.443 | |
| 2itn | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.443 | |
| 2ww4 | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.443 | |
| 3a3y | OBN | Sodium/potassium-transporting ATPase subunit alpha | / | 0.443 | |
| 3a4v | NAD | NDP-sugar epimerase | / | 0.443 | |
| 3cps | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.443 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.443 | |
| 3hng | 8ST | Vascular endothelial growth factor receptor 1 | 2.7.10.1 | 0.443 | |
| 3iaa | TYD | CalG2 | / | 0.443 | |
| 3if9 | FAD | Glycine oxidase | 1.4.3.19 | 0.443 | |
| 3k4c | FAD | Pyranose 2-oxidase | / | 0.443 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.443 | |
| 3sju | NDP | Keto reductase | / | 0.443 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.443 | |
| 3tqh | NDP | Quinone oxidoreductase | / | 0.443 | |
| 3w0y | DS4 | Vitamin D3 receptor | / | 0.443 | |
| 4o59 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.443 | |
| 4qe6 | JN3 | Bile acid receptor | / | 0.443 | |
| 4u97 | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.443 | |
| 4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.443 | |
| 4yt5 | H4M | H(2)-forming methylenetetrahydromethanopterin dehydrogenase-related protein MJ1338 | / | 0.443 | |
| 5ahs | FAD | Acyl-CoA dehydrogenase | / | 0.443 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.443 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 1qor | NDP | Quinone oxidoreductase 1 | / | 0.442 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.442 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.442 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.442 | |
| 2e9z | UTP | Genome polyprotein | / | 0.442 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.442 | |
| 2ql6 | ADP | Nicotinamide riboside kinase 1 | / | 0.442 | |
| 2zyb | KSL | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.442 | |
| 3d7k | D7K | Benzaldehyde lyase | / | 0.442 | |
| 3fkn | FKN | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.442 | |
| 3k4n | FAD | Pyranose 2-oxidase | / | 0.442 | |
| 3ol5 | SAW | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 3r9u | FAD | Thioredoxin reductase | / | 0.442 | |
| 3ruc | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.442 | |
| 3t2k | FAD | Sulfide-quinone reductase | / | 0.442 | |
| 3vwd | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.442 | |
| 3w2o | 03P | Epidermal growth factor receptor | 2.7.10.1 | 0.442 | |
| 4an9 | 2P7 | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.442 | |
| 4b7d | QLE | Cytochrome P450 monooxygenase PikC | / | 0.442 | |
| 4dpl | NAP | Malonyl-CoA reductase | 1.2.1.75 | 0.442 | |
| 4i3v | NAD | Aldehyde dehydrogenase (NAD+) | / | 0.442 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.442 | |
| 4k9d | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.442 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.442 | |
| 1geg | NAD | Diacetyl reductase [(S)-acetoin forming] | 1.1.1.304 | 0.441 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 1i7i | AZ2 | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 1j39 | UPG | DNA beta-glucosyltransferase | / | 0.441 | |
| 2ch6 | ADP | N-acetyl-D-glucosamine kinase | 2.7.1.59 | 0.441 | |
| 2gr1 | FAD | Ferredoxin reductase | / | 0.441 | |
| 2hrc | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.441 | |
| 2i5b | ADP | Pyridoxine kinase | / | 0.441 | |
| 2npa | MMB | Peroxisome proliferator-activated receptor alpha | / | 0.441 | |
| 2prh | 238 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.441 | |
| 2q7v | FAD | Thioredoxin reductase | / | 0.441 | |
| 2uxw | TH3 | Very long-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.9 | 0.441 | |
| 3csc | ACO | Citrate synthase, mitochondrial | 2.3.3.1 | 0.441 | |
| 3d5q | T30 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
| 3iae | D7K | Benzaldehyde lyase | / | 0.441 | |
| 3iod | A6D | Pantothenate synthetase | 6.3.2.1 | 0.441 | |
| 3qwf | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.441 | |
| 3sgl | FAD | tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC | / | 0.441 | |
| 3w32 | W32 | Epidermal growth factor receptor | 2.7.10.1 | 0.441 | |
| 4cf8 | V7H | Integrase | / | 0.441 | |
| 4die | C5P | Cytidylate kinase | / | 0.441 | |
| 4fqs | LYA | Thymidylate synthase ThyA | / | 0.441 | |
| 4ftm | 1HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 4h73 | NDP | Aldehyde dehydrogenase | / | 0.441 | |
| 4jlo | ADP | Adenylate kinase | / | 0.441 | |
| 6cts | CIC | Citrate synthase, mitochondrial | 2.3.3.1 | 0.441 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.440 | |
| 1err | RAL | Estrogen receptor | / | 0.440 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.440 | |
| 1hwz | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.440 | |
| 1lwi | NAP | 3-alpha-hydroxysteroid dehydrogenase | 1.1.1.50 | 0.440 | |
| 1m13 | HYF | Nuclear receptor subfamily 1 group I member 2 | / | 0.440 | |
| 1np7 | FAD | Cryptochrome DASH | / | 0.440 | |
| 1nqo | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.440 | |
| 1xu7 | CPS | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 | |
| 1yqd | NAP | Sinapyl alcohol dehydrogenase | / | 0.440 | |
| 1zmd | NAI | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.440 | |
| 2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.440 | |
| 2h8h | H8H | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.440 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.440 | |
| 2i4u | DJR | Protease | / | 0.440 | |
| 2oor | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.440 | |
| 2pob | GW4 | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 2xhd | 7T9 | Glutamate receptor 2 | / | 0.440 | |
| 2zjw | REF | Casein kinase II subunit alpha | 2.7.11.1 | 0.440 | |
| 3cyl | VIT | Basic phospholipase A2 homolog piratoxin-2 | / | 0.440 | |
| 3l8s | BFF | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 3vry | B43 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.440 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.440 | |
| 4h4q | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.440 | |
| 4i7f | NVE | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 4kqw | NAP | Ketol-acid reductoisomerase (NADP(+)) | / | 0.440 | |
| 4ocv | ANP | Aminoglycoside phosphotransferase | / | 0.440 | |
| 5koi | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.440 | |
| 4z9g | 1Q5 | Corticotropin-releasing factor receptor 1 | / | 0.440 |