Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
PDB ID | HET | Uniprot Name | EC Number |
---|---|---|---|
2r9x | WH6 | Beta-lactamase | 3.5.2.6 |
PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
---|---|---|---|---|---|
2r9x | WH6 | Beta-lactamase | 3.5.2.6 | 1.000 | |
2r9w | 23C | Beta-lactamase | 3.5.2.6 | 0.612 | |
1xgi | NST | Beta-lactamase | 3.5.2.6 | 0.606 | |
1xgj | HTC | Beta-lactamase | 3.5.2.6 | 0.591 | |
2pu2 | DK2 | Beta-lactamase | 3.5.2.6 | 0.542 | |
4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.451 | |
3ruf | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.447 | |
1bil | 0IU | Renin | 3.4.23.15 | 0.445 | |
1l2s | STC | Beta-lactamase | 3.5.2.6 | 0.444 | |
3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.444 | |
3cic | 316 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
3etd | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.443 | |
3d91 | REM | Renin | 3.4.23.15 | 0.442 | |
3djg | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.442 | |
2p2m | PRX | Acetyl-coenzyme A synthetase | / | 0.441 | |
3cls | FAD | Electron transfer flavoprotein subunit alpha | / | 0.440 | |
3jqp | A2P | Ferredoxin--NADP reductase, apicoplast | / | 0.440 | |
4amb | DUD | Putative glycosyl transferase | / | 0.440 |