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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2r6kGTXGlutathione S-transferase A12.5.1.18

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2r6kGTXGlutathione S-transferase A12.5.1.181.000
3l0hGTXGlutathione S-transferase A12.5.1.180.741
1k3yGTXGlutathione S-transferase A12.5.1.180.687
1pl2ABYGlutathione S-transferase A12.5.1.180.633
3ktlGTXGlutathione S-transferase A12.5.1.180.627
2r3xGTXGlutathione S-transferase A12.5.1.180.623
1guhGSBGlutathione S-transferase A12.5.1.180.620
1pl1ABYGlutathione S-transferase A12.5.1.180.616
1gsfEAAGlutathione S-transferase A12.5.1.180.535
1b48HAGGlutathione S-transferase A42.5.1.180.463
1uaeUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.458
4a1oAMZBifunctional purine biosynthesis protein PurH2.1.2.30.458
4qfxDGTDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.450
1nquRDL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.446
1qs2NADVip2Ac/0.446
4lutDCSAlanine racemase/0.440