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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2r3mSCXCyclin-dependent kinase 22.7.11.22

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2r3mSCXCyclin-dependent kinase 22.7.11.221.000
2r3p3SCCyclin-dependent kinase 22.7.11.220.757
2r3kSCQCyclin-dependent kinase 22.7.11.220.663
2r3lSCWCyclin-dependent kinase 22.7.11.220.628
3ezrEZRCyclin-dependent kinase 22.7.11.220.619
2c6iDT1Cyclin-dependent kinase 22.7.11.220.613
2r3iSCFCyclin-dependent kinase 22.7.11.220.612
4ek816KCyclin-dependent kinase 22.7.11.220.609
2r3jSCJCyclin-dependent kinase 22.7.11.220.608
2r3q5SCCyclin-dependent kinase 22.7.11.220.605
3r7yZ04Cyclin-dependent kinase 22.7.11.220.603
4fkt48KCyclin-dependent kinase 22.7.11.220.602
3iggEFQCyclin-dependent kinase 22.7.11.220.600
2r3o2SCCyclin-dependent kinase 22.7.11.220.597
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.596
2r3r6SCCyclin-dependent kinase 22.7.11.220.595
3lfsA07Cyclin-dependent kinase 22.7.11.220.594
4acm7YGCyclin-dependent kinase 22.7.11.220.594
3lfnA27Cyclin-dependent kinase 22.7.11.220.589
3rm618ZCyclin-dependent kinase 22.7.11.220.585
4fks46KCyclin-dependent kinase 22.7.11.220.585
2r3fSC8Cyclin-dependent kinase 22.7.11.220.584
2a0cCK9Cyclin-dependent kinase 22.7.11.220.582
3r1yX76Cyclin-dependent kinase 22.7.11.220.580
3r7iX9ICyclin-dependent kinase 22.7.11.220.575
3qruX19Cyclin-dependent kinase 22.7.11.220.573
3rm719ZCyclin-dependent kinase 22.7.11.220.573
2w06FRVCyclin-dependent kinase 22.7.11.220.572
1p2a5BNCyclin-dependent kinase 22.7.11.220.569
2w05FRTCyclin-dependent kinase 22.7.11.220.567
3ezvEZVCyclin-dependent kinase 22.7.11.220.567
1ykr628Cyclin-dependent kinase 22.7.11.220.566
3qxoX65Cyclin-dependent kinase 22.7.11.220.566
3lfqA28Cyclin-dependent kinase 22.7.11.220.565
3r1sX73Cyclin-dependent kinase 22.7.11.220.565
3pj8404Cyclin-dependent kinase 22.7.11.220.562
2uzoC62Cyclin-dependent kinase 22.7.11.220.560
3r7uX96Cyclin-dependent kinase 22.7.11.220.559
3rpv26ZCyclin-dependent kinase 22.7.11.220.559
3r7vZ02Cyclin-dependent kinase 22.7.11.220.558
2fvdLIACyclin-dependent kinase 22.7.11.220.554
3rahO1ZCyclin-dependent kinase 22.7.11.220.553
3sqq99ZCyclin-dependent kinase 22.7.11.220.553
3ig7EFPCyclin-dependent kinase 22.7.11.220.552
1pxmCK5Cyclin-dependent kinase 22.7.11.220.549
1ke7LS3Cyclin-dependent kinase 22.7.11.220.548
3rni21ZCyclin-dependent kinase 22.7.11.220.548
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.547
1v1k3FPCyclin-dependent kinase 22.7.11.220.545
3r8pZ46Cyclin-dependent kinase 22.7.11.220.541
2r64740Cyclin-dependent kinase 22.7.11.220.540
3qxpX64Cyclin-dependent kinase 22.7.11.220.540
3r8lZ30Cyclin-dependent kinase 22.7.11.220.540
3r83Z14Cyclin-dependent kinase 22.7.11.220.539
1w0xOLOCyclin-dependent kinase 22.7.11.220.538
2a4lRRCCyclin-dependent kinase 22.7.11.220.538
2r3gSC9Cyclin-dependent kinase 22.7.11.220.537
3qqhX0ACyclin-dependent kinase 22.7.11.220.537
1gih1PUCyclin-dependent kinase 22.7.11.220.536
3le62BZCyclin-dependent kinase 22.7.11.220.536
3s1h56ZCyclin-dependent kinase 22.7.11.220.536
4fkr45KCyclin-dependent kinase 22.7.11.220.535
2uznC96Cyclin-dependent kinase 22.7.11.220.534
3qzhX69Cyclin-dependent kinase 22.7.11.220.534
1y91CT9Cyclin-dependent kinase 22.7.11.220.533
2vttLZDCyclin-dependent kinase 22.7.11.220.533
3rjc06ZCyclin-dependent kinase 22.7.11.220.533
1h1r6CPCyclin-dependent kinase 22.7.11.220.531
2c6o4SPCyclin-dependent kinase 22.7.11.220.531
3r9nZ68Cyclin-dependent kinase 22.7.11.220.531
3qqfX07Cyclin-dependent kinase 22.7.11.220.530
3roy22ZCyclin-dependent kinase 22.7.11.220.530
1oitHDTCyclin-dependent kinase 22.7.11.220.529
3r71X86Cyclin-dependent kinase 22.7.11.220.529
2b52D42Cyclin-dependent kinase 22.7.11.220.528
4fkq42KCyclin-dependent kinase 22.7.11.220.528
3rak03ZCyclin-dependent kinase 22.7.11.220.527
3s2pPMUCyclin-dependent kinase 22.7.11.220.527
4lyn1YGCyclin-dependent kinase 22.7.11.220.527
2xmyCDKCyclin-dependent kinase 22.7.11.220.526
4fkpLS5Cyclin-dependent kinase 22.7.11.220.526
2w1hL0FCyclin-dependent kinase 22.7.11.220.525
3qwjX6ACyclin-dependent kinase 22.7.11.220.525
3r73X87Cyclin-dependent kinase 22.7.11.220.525
1fvt106Cyclin-dependent kinase 22.7.11.220.524
1pxoCK7Cyclin-dependent kinase 22.7.11.220.524
2c69CT8Cyclin-dependent kinase 22.7.11.220.524
3qqlX03Cyclin-dependent kinase 22.7.11.220.524
3r9dX6BCyclin-dependent kinase 22.7.11.220.524
1oiyN41Cyclin-dependent kinase 22.7.11.220.523
2bhhRYUCyclin-dependent kinase 22.7.11.220.523
2btrU73Cyclin-dependent kinase 22.7.11.220.523
1pxpCK8Cyclin-dependent kinase 22.7.11.220.522
3ddqRRCCyclin-dependent kinase 22.7.11.220.521
3qrtX14Cyclin-dependent kinase 22.7.11.220.521
3qtxX43Cyclin-dependent kinase 22.7.11.220.521
3rk909ZCyclin-dependent kinase 22.7.11.220.521
1w8cN69Cyclin-dependent kinase 22.7.11.220.520
1ke5LS1Cyclin-dependent kinase 22.7.11.220.519
4bgh3I6Cyclin-dependent kinase 22.7.11.220.517
1ke6LS2Cyclin-dependent kinase 22.7.11.220.516
1oiqHDUCyclin-dependent kinase 22.7.11.220.516
1b39ATPCyclin-dependent kinase 22.7.11.220.515
4fki09KCyclin-dependent kinase 22.7.11.220.515
2j9mPY8Cyclin-dependent kinase 22.7.11.220.514
2wpa889Cyclin-dependent kinase 22.7.11.220.514
1gii1PUCyclin-dependent kinase 22.7.11.220.513
3r7eX88Cyclin-dependent kinase 22.7.11.220.513
3qtuX44Cyclin-dependent kinase 22.7.11.220.512
3ral04ZCyclin-dependent kinase 22.7.11.220.512
1urwI1PCyclin-dependent kinase 22.7.11.220.511
1g5sI17Cyclin-dependent kinase 22.7.11.220.510
2vtnLZ7Cyclin-dependent kinase 22.7.11.220.509
2vu3LZECyclin-dependent kinase 22.7.11.220.509
3qx2X63Cyclin-dependent kinase 22.7.11.220.509
4fkv61KCyclin-dependent kinase 22.7.11.220.509
2vtqLZACyclin-dependent kinase 22.7.11.220.508
3rmf20ZCyclin-dependent kinase 22.7.11.220.508
3rpo24ZCyclin-dependent kinase 22.7.11.220.508
3qtrX36Cyclin-dependent kinase 22.7.11.220.507
2bheBRYCyclin-dependent kinase 22.7.11.220.506
3qtzX42Cyclin-dependent kinase 22.7.11.220.505
1ke8LS4Cyclin-dependent kinase 22.7.11.220.503
3r28XA0Cyclin-dependent kinase 22.7.11.220.503
2b53D23Cyclin-dependent kinase 22.7.11.220.502
2vtsLZCCyclin-dependent kinase 22.7.11.220.502
1oguST8Cyclin-dependent kinase 22.7.11.220.501
2b55D31Cyclin-dependent kinase 22.7.11.220.500
4eor4SPCyclin-dependent kinase 22.7.11.220.500
2vv9IM9Cyclin-dependent kinase 22.7.11.220.499
3unk0BYCyclin-dependent kinase 22.7.11.220.499
1oirHDYCyclin-dependent kinase 22.7.11.220.498
1vyw292Cyclin-dependent kinase 22.7.11.220.498
3r9hZ67Cyclin-dependent kinase 22.7.11.220.498
1pxlCK4Cyclin-dependent kinase 22.7.11.220.497
2vtiLZ3Cyclin-dependent kinase 22.7.11.220.496
4bcpT3CCyclin-dependent kinase 22.7.11.220.496
2duv371Cyclin-dependent kinase 22.7.11.220.495
3qu0X40Cyclin-dependent kinase 22.7.11.220.495
3sw418KCyclin-dependent kinase 22.7.11.220.495
1h0vUN4Cyclin-dependent kinase 22.7.11.220.494
3sw719KCyclin-dependent kinase 22.7.11.220.494
1vyzN5BCyclin-dependent kinase 22.7.11.220.493
2w17I19Cyclin-dependent kinase 22.7.11.220.493
3qzfX66Cyclin-dependent kinase 22.7.11.220.493
3rk708ZCyclin-dependent kinase 22.7.11.220.493
4erwSTUCyclin-dependent kinase 22.7.11.220.493
1h1s4SPCyclin-dependent kinase 22.7.11.220.492
1aq1STUCyclin-dependent kinase 22.7.11.220.491
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.491
3qzgX67Cyclin-dependent kinase 22.7.11.220.491
1e9hINRCyclin-dependent kinase 22.7.11.220.490
3r8zZ63Cyclin-dependent kinase 22.7.11.220.490
3raiX85Cyclin-dependent kinase 22.7.11.220.490
3tiz3TICyclin-dependent kinase 22.7.11.220.490
1h0w207Cyclin-dependent kinase 22.7.11.220.488
2c68CT6Cyclin-dependent kinase 22.7.11.220.487
1pxkCK3Cyclin-dependent kinase 22.7.11.220.486
3dogNNNCyclin-dependent kinase 22.7.11.220.486
3fz1B98Cyclin-dependent kinase 22.7.11.220.486
3qqkX02Cyclin-dependent kinase 22.7.11.220.486
2c6lDT4Cyclin-dependent kinase 22.7.11.220.485
3pxyJWSCyclin-dependent kinase 22.7.11.220.485
4fx360KCyclin-dependent kinase 22.7.11.220.485
1oiuN76Cyclin-dependent kinase 22.7.11.220.484
3rk507ZCyclin-dependent kinase 22.7.11.220.483
4fkw62KCyclin-dependent kinase 22.7.11.220.483
4kd11QKCyclin-dependent kinase 22.7.11.220.482
2wihP48Cyclin-dependent kinase 22.7.11.220.481
3qziX72Cyclin-dependent kinase 22.7.11.220.481
3r8vZ62Cyclin-dependent kinase 22.7.11.220.481
2iw94SPCyclin-dependent kinase 22.7.11.220.480
4eok4SPCyclin-dependent kinase 22.7.11.220.479
3ti1B49Cyclin-dependent kinase 22.7.11.220.478
4bcmT7ZCyclin-dependent kinase 22.7.11.220.478
1oi9N20Cyclin-dependent kinase 22.7.11.220.476
4ek610KCyclin-dependent kinase 22.7.11.220.476
1pyePM1Cyclin-dependent kinase 22.7.11.220.474
2btsU32Cyclin-dependent kinase 22.7.11.220.474
3r1qX75Cyclin-dependent kinase 22.7.11.220.474
3ddpRC8Cyclin-dependent kinase 22.7.11.220.473
4fko20KCyclin-dependent kinase 22.7.11.220.472
1ke9LS5Cyclin-dependent kinase 22.7.11.220.471
2c5yMTWCyclin-dependent kinase 22.7.11.220.471
2x1nX1NCyclin-dependent kinase 22.7.11.220.471
3rkb12ZCyclin-dependent kinase 22.7.11.220.471
1b38ATPCyclin-dependent kinase 22.7.11.220.470
1e1xNW1Cyclin-dependent kinase 22.7.11.220.470
2iw84SPCyclin-dependent kinase 22.7.11.220.470
2wxvWXVCyclin-dependent kinase 22.7.11.220.470
4eol1ROCyclin-dependent kinase 22.7.11.220.468
1h1q2A6Cyclin-dependent kinase 22.7.11.220.467
1pkdUCNCyclin-dependent kinase 22.7.11.220.467
2c6mDT5Cyclin-dependent kinase 22.7.11.220.467
2c4g514Cyclin-dependent kinase 22.7.11.220.466
2pvlP55Casein kinase II subunit alpha2.7.11.10.465
2vthLZ2Cyclin-dependent kinase 22.7.11.220.465
4eon1ROCyclin-dependent kinase 22.7.11.220.465
4ez30S0Cyclin-dependent kinase 22.7.11.220.465
3qwkX62Cyclin-dependent kinase 22.7.11.220.463
2iw6QQ2Cyclin-dependent kinase 22.7.11.220.462
3r6xX84Cyclin-dependent kinase 22.7.11.220.462
4fklCK2Cyclin-dependent kinase 22.7.11.220.462
1unlRRCCyclin-dependent-like kinase 52.7.11.10.461
3nynSGVG protein-coupled receptor kinase 62.7.11.160.461
2c6kDT2Cyclin-dependent kinase 22.7.11.220.460
3s0o50ZCyclin-dependent kinase 22.7.11.220.460
3unj0BXCyclin-dependent kinase 22.7.11.220.460
1h1pCMGCyclin-dependent kinase 22.7.11.220.458
4bcoT6QCyclin-dependent kinase 22.7.11.220.458
1ckpPVBCyclin-dependent kinase 22.7.11.220.457
3qtqX35Cyclin-dependent kinase 22.7.11.220.457
3wblPDYCyclin-dependent kinase 22.7.11.220.457
3tnwF18Cyclin-dependent kinase 22.7.11.220.456
4cfnJYMCyclin-dependent kinase 22.7.11.220.456
2b54D05Cyclin-dependent kinase 22.7.11.220.455
2i40BLZCyclin-dependent kinase 22.7.11.220.455
3r8uZ31Cyclin-dependent kinase 22.7.11.220.455
3my5RFZCyclin-dependent kinase 22.7.11.220.453
3sheI85MAP kinase-activated protein kinase 32.7.11.10.453
1gij2PUCyclin-dependent kinase 22.7.11.220.451
3ql8X01Cyclin-dependent kinase 22.7.11.220.451
3qtsX46Cyclin-dependent kinase 22.7.11.220.451
1fvv107Cyclin-dependent kinase 22.7.11.220.450
1r78FMDCyclin-dependent kinase 22.7.11.220.450
2cchATPCyclin-dependent kinase 22.7.11.220.450
4bcnT9NCyclin-dependent kinase 22.7.11.220.450
1di8DTQCyclin-dependent kinase 22.7.11.220.449
3at4CCKCasein kinase II subunit alpha2.7.11.10.447
3rpy27ZCyclin-dependent kinase 22.7.11.220.447
2ds11CDCyclin-dependent kinase 22.7.11.220.446
3rzb02ZCyclin-dependent kinase 22.7.11.220.446
2c6tDT5Cyclin-dependent kinase 22.7.11.220.445
2uzbC75Cyclin-dependent kinase 22.7.11.220.445
3py0SU9Cyclin-dependent kinase 22.7.11.220.444
4bcqTJFCyclin-dependent kinase 22.7.11.220.444
1v0oINRCell division control protein 2 homolog2.7.11.220.443
2zjwREFCasein kinase II subunit alpha2.7.11.10.442
3lq5SLQCyclin-dependent kinase 92.7.11.220.442
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.441
4fv3EK6Mitogen-activated protein kinase 12.7.11.240.441
2uzeC95Cyclin-dependent kinase 22.7.11.220.440