scPDB - Distribution of Binding site Similarity values of 2qzr entry / Site 1

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
2qzr	S79	Queuine tRNA-ribosyltransferase	2.4.2.29

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
2qzr	S79	Queuine tRNA-ribosyltransferase	2.4.2.29	1.000
2bbf	344	Queuine tRNA-ribosyltransferase	2.4.2.29	0.601
1k4h	APQ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.600
1n2v	BDI	Queuine tRNA-ribosyltransferase	2.4.2.29	0.599
1k4g	AIQ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.597
1y5x	E89	Queuine tRNA-ribosyltransferase	2.4.2.29	0.576
4gg9	0WW	Queuine tRNA-ribosyltransferase	2.4.2.29	0.564
1q4w	DQU	Queuine tRNA-ribosyltransferase	2.4.2.29	0.551
4fps	0UX	Queuine tRNA-ribosyltransferase	2.4.2.29	0.550
4gh1	0WX	Queuine tRNA-ribosyltransferase	2.4.2.29	0.548
3gc5	2MQ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.538
4q8p	CKR	Queuine tRNA-ribosyltransferase	2.4.2.29	0.531
1y5w	NEZ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.530
1f3e	DPZ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.527
2z1w	BDI	Queuine tRNA-ribosyltransferase	2.4.2.29	0.521
1q63	AIQ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.520
4giy	0WY	Queuine tRNA-ribosyltransferase	2.4.2.29	0.516
3ge7	AFQ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.515
1efz	PRF	Queuine tRNA-ribosyltransferase	2.4.2.29	0.511
3gc4	AAQ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.511
4fr1	0V2	Queuine tRNA-ribosyltransferase	2.4.2.29	0.509
4fsa	0V3	Queuine tRNA-ribosyltransferase	2.4.2.29	0.492
4o9c	COA	Acetyl-CoA acetyltransferase	2.3.1.9	0.492
1p0e	PRF	Queuine tRNA-ribosyltransferase	2.4.2.29	0.490
4gi4	0EX	Queuine tRNA-ribosyltransferase	2.4.2.29	0.486
1q65	BHB	Queuine tRNA-ribosyltransferase	2.4.2.29	0.483
2z1x	PRF	Queuine tRNA-ribosyltransferase	2.4.2.29	0.479
1c3x	8IG	Purine nucleoside phosphorylase	2.4.2.1	0.478
1f8g	NAD	NAD(P) transhydrogenase subunit alpha part 1	1.6.1.2	0.478
3sm0	AEK	Queuine tRNA-ribosyltransferase	2.4.2.29	0.476
2w3a	TOP	Dihydrofolate reductase	1.5.1.3	0.474
3qgf	46F	Genome polyprotein	2.7.7.48	0.472
1gky	5GP	Guanylate kinase	2.7.4.8	0.471
3cow	52H	Pantothenate synthetase	6.3.2.1	0.471
4hsh	QEI	Queuine tRNA-ribosyltransferase	2.4.2.29	0.471
4i8v	BHF	Cytochrome P450 1A1	1.14.14.1	0.469
2cle	F6F	Tryptophan synthase alpha chain	/	0.468
3img	BZ3	Pantothenate synthetase	6.3.2.1	0.468
2ivn	ANP	tRNA N6-adenosine threonylcarbamoyltransferase	/	0.467
1pqc	444	Oxysterols receptor LXR-beta	/	0.465
1cf3	FAD	Glucose oxidase	1.1.3.4	0.464
3rsv	3RS	Beta-secretase 1	3.4.23.46	0.463
3arv	SAU	Chitinase A	/	0.460
1ez0	NAP	NADP-dependent fatty aldehyde dehydrogenase	1.2.1.4	0.459
1pq9	44B	Oxysterols receptor LXR-beta	/	0.459
3oaf	OAG	Dihydrofolate reductase	1.5.1.3	0.458
4bbh	YBN	Glycylpeptide N-tetradecanoyltransferase	/	0.456
4gh3	0EV	Queuine tRNA-ribosyltransferase	2.4.2.29	0.456
2jds	L20	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.455
3h3r	14H	Collagen type IV alpha-3-binding protein	/	0.455
3bll	BPQ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.454
3coy	53H	Pantothenate synthetase	6.3.2.1	0.454
4g95	OAG	Dihydrofolate reductase	1.5.1.3	0.454
1q0z	AKA	Aclacinomycin methylesterase RdmC	3.1.1.95	0.453
2e16	SAH	Diphthine synthase	/	0.453
3gxo	MQA	Mitomycin biosynthesis 6-O-methyltransferase	/	0.453
3ox4	NAD	Alcohol dehydrogenase 2	1.1.1.1	0.453
2pid	YSA	Tyrosine--tRNA ligase, mitochondrial	6.1.1.1	0.452
1jnr	FAD	Adenylylsulfate reductase, subunit A (AprA)	/	0.451
4f1y	CNI	Glutamate receptor 3	/	0.451
4lwa	Q13	Nitric oxide synthase oxygenase	1.14.13.165	0.451
3nxv	D2F	Dihydrofolate reductase	1.5.1.3	0.450
5bp9	SAH	Putative methyltransferase protein	/	0.450
1pxg	PRF	Queuine tRNA-ribosyltransferase	2.4.2.29	0.449
4h6p	FMN	Chromate reductase	/	0.449
4x7z	ZM3	Mycinamicin III 3''-O-methyltransferase	2.1.1.237	0.449
1sq5	ADP	Pantothenate kinase	2.7.1.33	0.448
1vbi	NAD	Malate/L-lactate dehydrogenase family protein	/	0.448
1q66	KMB	Queuine tRNA-ribosyltransferase	2.4.2.29	0.447
4ug9	1EW	Nitric oxide synthase oxygenase	1.14.13.165	0.447
2fm5	M99	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.446
2y03	5FW	Beta-1 adrenergic receptor	/	0.446
3zxi	TYA	Tyrosine--tRNA ligase, mitochondrial	6.1.1.1	0.446
4gv0	8ME	Poly [ADP-ribose] polymerase 3	2.4.2.30	0.446
5iu8	6DZ	Adenosine receptor A2a	/	0.446
1r5y	DQU	Queuine tRNA-ribosyltransferase	2.4.2.29	0.445
1yhj	R6C	Pyridoxal kinase	2.7.1.35	0.445
2dvl	FAD	Acyl-CoA dehydrogenase	/	0.445
2gnh	H52	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.445
3ioc	A5D	Pantothenate synthetase	6.3.2.1	0.445
3rl4	5GP	Metallophosphoesterase MPPED2	3.1	0.445
4jlm	1NN	Deoxycytidine kinase	2.7.1.74	0.445
4xq9	NAD	Homospermidine synthase	2.5.1.44	0.445
5c6c	CMP	cGMP-dependent protein kinase 2	2.7.11.12	0.445
5k2b	ZMA	Adenosine receptor A2a	/	0.445
2azz	TCH	Phospholipase A2, major isoenzyme	3.1.1.4	0.444
3b4y	F42	F420-dependent glucose-6-phosphate dehydrogenase	/	0.444
4bv9	NDP	Ketimine reductase mu-crystallin	1.5.1.25	0.444
4mlp	2CX	Cryptochrome-2	/	0.444
3eml	ZMA	Adenosine receptor A2a	/	0.444
3coz	54H	Pantothenate synthetase	6.3.2.1	0.443
4a30	QMI	Glycylpeptide N-tetradecanoyltransferase	/	0.443
1ozq	PRF	Queuine tRNA-ribosyltransferase	2.4.2.29	0.442
2azy	CHD	Phospholipase A2, major isoenzyme	3.1.1.4	0.442
2f2s	COA	Acetyl-CoA acetyltransferase, mitochondrial	2.3.1.9	0.442
2fja	FAD	Adenylylsulfate reductase, subunit A (AprA)	/	0.442
2h94	FAD	Lysine-specific histone demethylase 1A	1	0.442
2p2q	PRX	Acetyl-coenzyme A synthetase	/	0.442
3c0g	3AM	Peripheral plasma membrane protein CASK	2.7.11.1	0.442
3cr0	809	Wee1-like protein kinase	2.7.10.2	0.442
3qi4	IBM	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	/	0.442
4iwo	1H4	Serine/threonine-protein kinase TBK1	2.7.11.1	0.442
4rh1	0TT	Spore photoproduct lyase	/	0.442
1q0r	AKT	Aclacinomycin methylesterase RdmC	3.1.1.95	0.441
3dyl	PCG	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	/	0.441
4cdm	FO1	Deoxyribodipyrimidine photolyase	/	0.441
4hvx	QEI	Queuine tRNA-ribosyltransferase	2.4.2.29	0.441
5c1m	CLR	Mu-type opioid receptor	/	0.441
1lb9	DNQ	Glutamate receptor 2	/	0.440
1t4c	COA	Formyl-CoA:oxalate CoA-transferase	/	0.440
2ow0	6MR	Matrix metalloproteinase-9	3.4.24.35	0.440
3ckq	UPG	Glucosyl-3-phosphoglycerate synthase	2.4.1.266	0.440
4s1i	PLP	Pyridoxal kinase, putative	/	0.440
3uzc	T4E	Adenosine receptor A2a	/	0.440