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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2qu6857Vascular endothelial growth factor receptor 22.7.10.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2qu6857Vascular endothelial growth factor receptor 22.7.10.11.000
3vnt0JAVascular endothelial growth factor receptor 22.7.10.10.563
3b8q900Vascular endothelial growth factor receptor 22.7.10.10.557
3cp9C19Vascular endothelial growth factor receptor 22.7.10.10.538
3dtwA96Vascular endothelial growth factor receptor 22.7.10.10.524
2p2i608Vascular endothelial growth factor receptor 22.7.10.10.516
2oiqSTIProto-oncogene tyrosine-protein kinase Src2.7.10.20.514
3efl706Vascular endothelial growth factor receptor 22.7.10.10.512
4c8b0LIReceptor-interacting serine/threonine-protein kinase 22.7.11.10.506
2hyySTITyrosine-protein kinase ABL12.7.10.20.502
4o2z046Mitogen-activated protein kinase/0.496
4aseAV9Vascular endothelial growth factor receptor 22.7.10.10.493
2og81N8Tyrosine-protein kinase Lck2.7.10.20.492
1iepSTITyrosine-protein kinase ABL12.7.10.20.483
4agwNG7Proto-oncogene tyrosine-protein kinase Src2.7.10.20.480
3hng8STVascular endothelial growth factor receptor 12.7.10.10.474
4fc00T2Serine/threonine-protein kinase B-raf2.7.11.10.464
3hv5R24Mitogen-activated protein kinase 14/0.462
4qrc0LIFibroblast growth factor receptor 42.7.10.10.447
4ksp1SUSerine/threonine-protein kinase B-raf2.7.11.10.441