sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2qt0 | NNR | Nicotinamide riboside kinase 1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2qt0 | NNR | Nicotinamide riboside kinase 1 | / | 1.000 | |
| 2ql6 | TIZ | Nicotinamide riboside kinase 1 | / | 0.507 | |
| 2g7y | MO9 | Cathepsin S | 3.4.22.27 | 0.479 | |
| 2rd6 | 78P | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.459 | |
| 3l3l | L3L | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.457 | |
| 4dbw | 511 | Aldo-keto reductase family 1 member C3 | / | 0.455 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.454 | |
| 1q6n | P90 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.453 | |
| 1ro9 | 8BR | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.452 | |
| 2c1z | KMP | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.452 | |
| 4g1n | NZT | Pyruvate kinase PKM | 2.7.1.40 | 0.450 | |
| 1nqu | RDL | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.445 | |
| 1udt | VIA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.444 | |
| 4kn1 | 04J | Folate receptor beta | / | 0.443 | |
| 3w5e | NVW | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.442 | |
| 5a4w | QCT | Glutathione S-transferase F2 | 2.5.1.18 | 0.442 | |
| 1xf0 | ASD | Aldo-keto reductase family 1 member C3 | / | 0.440 |