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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2qo9ANPEphrin type-A receptor 32.7.10.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2qo9ANPEphrin type-A receptor 32.7.10.11.000
4g2fC07Ephrin type-A receptor 32.7.10.10.645
2qo7ANPEphrin type-A receptor 32.7.10.10.638
4gk3L87Ephrin type-A receptor 32.7.10.10.597
2qoqANPEphrin type-A receptor 32.7.10.10.595
2henADPEphrin type-B receptor 22.7.10.10.584
2qocANPEphrin type-A receptor 32.7.10.10.584
2y6o1N1Ephrin type-A receptor 42.7.10.10.581
1jpaANPEphrin type-B receptor 22.7.10.10.561
4gk2L66Ephrin type-A receptor 32.7.10.10.561
4gk4L90Ephrin type-A receptor 32.7.10.10.557
2xyuQ9GEphrin type-A receptor 42.7.10.10.549
4gmy0X5Tyrosine-protein kinase JAK2/0.529
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.524
2acxANPG protein-coupled receptor kinase 62.7.11.160.524
4bb432WEphrin type-B receptor 42.7.10.10.523
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.521
2yn8STUEphrin type-B receptor 42.7.10.10.521
3vjoANPEpidermal growth factor receptor2.7.10.10.516
2py3ACPFibroblast growth factor receptor 2/0.514
2vwu7X1Ephrin type-B receptor 42.7.10.10.514
4riyADPEpidermal growth factor receptor2.7.10.10.512
2xvdAS6Ephrin type-B receptor 42.7.10.10.509
4mxxDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.509
2wmxZY6Serine/threonine-protein kinase Chk12.7.11.10.508
2ituITQEpidermal growth factor receptor2.7.10.10.506
2hog710Serine/threonine-protein kinase Chk12.7.11.10.504
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.504
2itvANPEpidermal growth factor receptor2.7.10.10.499
3zewSTUEphrin type-B receptor 42.7.10.10.499
4fswHK6Serine/threonine-protein kinase Chk12.7.11.10.498
4aw0ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.497
1bygSTUTyrosine-protein kinase CSK/0.496
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.496
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.496
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.495
1qcfPP1Tyrosine-protein kinase HCK2.7.10.20.493
5e8wSTUTGF-beta receptor type-12.7.11.300.493
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.492
4i231C9Epidermal growth factor receptor2.7.10.10.492
2ym3YM3Serine/threonine-protein kinase Chk12.7.11.10.490
3ac1KZITyrosine-protein kinase Lck2.7.10.20.490
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.490
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.489
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.489
4xey1N1Tyrosine-protein kinase ABL12.7.10.20.489
2ittAEEEpidermal growth factor receptor2.7.10.10.488
2of4979Tyrosine-protein kinase Lck2.7.10.20.488
2wmtZYTSerine/threonine-protein kinase Chk12.7.11.10.488
2x9fX9FEphrin type-B receptor 42.7.10.10.487
2ym5YM5Serine/threonine-protein kinase Chk12.7.11.10.487
4wkqIREEpidermal growth factor receptor2.7.10.10.487
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.487
2pzpACPFibroblast growth factor receptor 2/0.486
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.486
1u54ACPActivated CDC42 kinase 1/0.484
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.484
4oa9ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.484
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.483
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.483
2wmuZYUSerine/threonine-protein kinase Chk12.7.11.10.483
3vs2VSBTyrosine-protein kinase HCK2.7.10.20.483
4jia1K3Tyrosine-protein kinase JAK2/0.483
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.482
2itnANPEpidermal growth factor receptor2.7.10.10.482
4j97ACPFibroblast growth factor receptor 2/0.482
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.481
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.480
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.480
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.480
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.479
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.479
4fl1ANPTyrosine-protein kinase SYK2.7.10.20.479
4qmtH1NSerine/threonine-protein kinase 242.7.11.10.479
2vwz7X6Ephrin type-B receptor 42.7.10.10.478
2wmwZYWSerine/threonine-protein kinase Chk12.7.11.10.478
1zrzBI1Protein kinase C iota type2.7.11.130.477
2pwlACPFibroblast growth factor receptor 2/0.477
2pz5ACPFibroblast growth factor receptor 2/0.477
2ym44YMSerine/threonine-protein kinase Chk12.7.11.10.477
3gxlQIGTGF-beta receptor type-12.7.11.300.477
3vw6IM6Mitogen-activated protein kinase kinase kinase 52.7.11.250.477
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.476
2vwx7X4Ephrin type-B receptor 42.7.10.10.476
2vx17X8Ephrin type-B receptor 42.7.10.10.476
1oiyN41Cyclin-dependent kinase 22.7.11.220.475
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.475
2wmsZYSSerine/threonine-protein kinase Chk12.7.11.10.475
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.475
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.474
2bdjHETProto-oncogene tyrosine-protein kinase Src2.7.10.20.474
2j0m4STFocal adhesion kinase 12.7.10.20.474
2of2547Tyrosine-protein kinase Lck2.7.10.20.474
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.474
4gvjADPNon-receptor tyrosine-protein kinase TYK22.7.10.20.474
2hk51BMTyrosine-protein kinase HCK2.7.10.20.473
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.473
4wboANWRhodopsin kinase/0.473
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.472
4k33ACPFibroblast growth factor receptor 32.7.10.10.472
1m17AQ4Epidermal growth factor receptor2.7.10.10.470
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.470
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.470
4c58824Cyclin-G-associated kinase2.7.11.10.470
4fob0USALK tyrosine kinase receptor2.7.10.10.470
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.469
2vwy7X5Ephrin type-B receptor 42.7.10.10.469
4dymIYZActivin receptor type-12.7.11.300.469
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.468
2eb3ANPEpidermal growth factor receptor2.7.10.10.468
1mqbANPEphrin type-A receptor 22.7.10.10.467
2biyATP3-phosphoinositide-dependent protein kinase 12.7.11.10.467
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.467
3qc9ADPRhodopsin kinase/0.467
4c02TAKActivin receptor type-12.7.11.300.467
4j95ACPFibroblast growth factor receptor 2/0.467
4nm0ADPGlycogen synthase kinase-3 beta2.7.11.260.467
5e8xSTUTGF-beta receptor type-12.7.11.300.467
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.466
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.466
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.465
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.465
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.465
2etm7PYFocal adhesion kinase 12.7.10.20.465
2wmrZYRSerine/threonine-protein kinase Chk12.7.11.10.465
3cr0809Wee1-like protein kinase2.7.10.20.465
3lcdBDYMacrophage colony-stimulating factor 1 receptor2.7.10.10.465
3mdvCL6Cholesterol 24-hydroxylase/0.465
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.465
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.465
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.464
2wmvZYVSerine/threonine-protein kinase Chk12.7.11.10.464
3a4oSTUTyrosine-protein kinase Lyn2.7.10.20.464
3cukFADD-amino-acid oxidase1.4.3.30.464
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.464
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.464
4jq8KJ8Epidermal growth factor receptor2.7.10.10.464
4qo9627Serine/threonine-protein kinase 242.7.11.10.464
1u4dDBQActivated CDC42 kinase 1/0.463
2c0tL3GTyrosine-protein kinase HCK2.7.10.20.463
2vx07X7Ephrin type-B receptor 42.7.10.10.463
2yitYITSerine/threonine-protein kinase Chk22.7.11.10.463
3mpjFADGlutaryl-CoA dehydrogenase1.3.99.320.463
4mxoDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.463
4rrvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.463
1gufNDPEnoyl-[acyl-carrier-protein] reductase 1, mitochondrial1.3.1.100.462
1pkgADPMast/stem cell growth factor receptor Kit2.7.10.10.462
1q8yADPSerine/threonine-protein kinase SKY12.7.11.10.462
1vjy460TGF-beta receptor type-12.7.11.300.462
2zva1N1Tyrosine-protein kinase Lyn2.7.10.20.462
3rwpABQ3-phosphoinositide-dependent protein kinase 12.7.11.10.462
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.462
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.462
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.462
1uu3LY43-phosphoinositide-dependent protein kinase 12.7.11.10.461
1y57MPZProto-oncogene tyrosine-protein kinase Src2.7.10.20.461
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.461
2vww7X2Ephrin type-B receptor 42.7.10.10.461
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.461
4ft9H4KSerine/threonine-protein kinase Chk12.7.11.10.461
1gqtACPRibokinase/0.460
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.460
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.460
2dcnADP2-keto-3-deoxy-gluconate kinase/0.460
2itpAEEEpidermal growth factor receptor2.7.10.10.460
2rioADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.460
3ac3KSHTyrosine-protein kinase Lck2.7.10.20.460
3tucFPWTyrosine-protein kinase SYK2.7.10.20.460
4id71G0Activated CDC42 kinase 1/0.460
4jq7KJQEpidermal growth factor receptor2.7.10.10.460
4qmzB49Serine/threonine-protein kinase 242.7.11.10.460
2hxq373Serine/threonine-protein kinase Chk12.7.11.10.459
2izrBRKCasein kinase I isoform gamma-32.7.11.10.459
3v5j0F2Tyrosine-protein kinase ITK/TSK2.7.10.20.459
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.458
2v7a627Tyrosine-protein kinase ABL12.7.10.20.458
2wotZZGTGF-beta receptor type-12.7.11.300.458
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.458
3ad6KSCTyrosine-protein kinase Lck2.7.10.20.458
3hmm855TGF-beta receptor type-12.7.11.300.458
4c57FEFCyclin-G-associated kinase2.7.11.10.458
4fsnA58Serine/threonine-protein kinase Chk12.7.11.10.458
4jr3KJREpidermal growth factor receptor2.7.10.10.458
4mf029ZTyrosine-protein kinase ITK/TSK2.7.10.20.458
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.458
5a3cNADSIR2 family protein/0.458
1c9k5GPBifunctional adenosylcobalamin biosynthesis protein CobU/0.457
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
4j99ACPFibroblast growth factor receptor 2/0.457
4l3l5FIRibosomal protein S6 kinase beta-12.7.11.10.457
1rw8580TGF-beta receptor type-12.7.11.300.456
1zthADPRIO-type serine/threonine-protein kinase Rio12.7.11.10.456
3i60E86Mitogen-activated protein kinase 12.7.11.240.456
3ue4DB8Tyrosine-protein kinase ABL12.7.10.20.456
3uqdATPATP-dependent 6-phosphofructokinase isozyme 22.7.1.110.456
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.456
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.455
1pyxANPGlycogen synthase kinase-3 beta2.7.11.260.455
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.455
2itzIREEpidermal growth factor receptor2.7.10.10.455
2izuP01Casein kinase I isoform gamma-32.7.11.10.455
2p2h994Vascular endothelial growth factor receptor 22.7.10.10.455
2wxvWXVCyclin-dependent kinase 22.7.11.220.455
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.455
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.454
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.454
2x2mX2MProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.454
3a7jADPSerine/threonine-protein kinase 242.7.11.10.454
3c4wATPRhodopsin kinase/0.454
3sj7NDP3-oxoacyl-(Acyl-carrier-protein) reductase, putative/0.454
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.454
4ct1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.454
4enhFVXCholesterol 24-hydroxylase/0.454
4fyn0VETyrosine-protein kinase SYK2.7.10.20.454
4mxyDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.454
4mxzDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.454
5aacVGHALK tyrosine kinase receptor2.7.10.10.454
2yexYEXSerine/threonine-protein kinase Chk12.7.11.10.453
3bkbSTUTyrosine-protein kinase Fes/Fps2.7.10.20.453
3c50ADPRhodopsin kinase/0.453
3oom507Activin receptor type-12.7.11.300.453
3we45FIRibosomal protein S6 kinase beta-12.7.11.10.453
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.453
4gb90WRPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.453
4i22IREEpidermal growth factor receptor2.7.10.10.453
4ji91M3Tyrosine-protein kinase JAK2/0.453
4qmpDKISerine/threonine-protein kinase 242.7.11.10.453
5aaaVGHALK tyrosine kinase receptor2.7.10.10.453
1siqFADGlutaryl-CoA dehydrogenase, mitochondrial1.3.8.60.452
2gs7ANPEpidermal growth factor receptor2.7.10.10.452
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.452
3vryB43Tyrosine-protein kinase HCK2.7.10.20.452
4kioG5KTyrosine-protein kinase ITK/TSK2.7.10.20.452
4qmlANPSerine/threonine-protein kinase 242.7.11.10.452
4qms1N1Serine/threonine-protein kinase 242.7.11.10.452
4qnaX11Serine/threonine-protein kinase 242.7.11.10.452
2b7aIZATyrosine-protein kinase JAK2/0.451
2i0y5CNMacrophage colony-stimulating factor 1 receptor2.7.10.10.451
2ycqUPXSerine/threonine-protein kinase Chk22.7.11.10.451
3a7hATPSerine/threonine-protein kinase 242.7.11.10.451
3fhyATPPyridoxal kinase2.7.1.350.451
3iahNAPPutative oxoacyl-(Acyl carrier protein) reductase/0.451
3nlb5BESerine/threonine-protein kinase Chk12.7.11.10.451
4ezk0SDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.451
4yryFADGlutamate synthase, beta subunit/0.451
1csnATPCasein kinase I homolog 12.7.11.10.450
2fy4COACholine O-acetyltransferase2.3.1.60.450
3b8r887Vascular endothelial growth factor receptor 22.7.10.10.450
3gw9VNILanosterol 14-alpha-demethylase/0.450
3t8oATPRhodopsin kinase/0.450
4dbzNDPPutative ketoacyl reductase1.3.10.450
4ftaH5KSerine/threonine-protein kinase Chk12.7.11.10.450
4jlcSU6Serine/threonine-protein kinase TBK12.7.11.10.450
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.449
2p33J07Mitogen-activated protein kinase 102.7.11.240.449
2ycrHCWSerine/threonine-protein kinase Chk22.7.11.10.449
4dggI76Proto-oncogene tyrosine-protein kinase Src2.7.10.20.449
4fsqHK3Serine/threonine-protein kinase Chk12.7.11.10.449
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.449
1iidNHMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.448
2pvyACPFibroblast growth factor receptor 2/0.448
2pziAXXSerine/threonine-protein kinase PknG2.7.11.10.448
2vd5BI8Myotonin-protein kinase2.7.11.10.448
2vkvTDCTetracycline repressor protein class D/0.448
2yfxVGHALK tyrosine kinase receptor2.7.10.10.448
2zm1KSFTyrosine-protein kinase Lck2.7.10.20.448
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.448
4b99R4LMitogen-activated protein kinase 72.7.11.240.448
4dieC5PCytidylate kinase/0.448
4fv3EK6Mitogen-activated protein kinase 12.7.11.240.448
4i5vB4PDiadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase 2/0.448
4utdACPAurora kinase A2.7.11.10.448
1bwsNDPGDP-L-fucose synthase/0.447
2cgv3B3Serine/threonine-protein kinase Chk12.7.11.10.447
2pmlANPUncharacterized protein/0.447
3ac2KSETyrosine-protein kinase Lck2.7.10.20.447
3c4xATPRhodopsin kinase/0.447
3q4zANPSerine/threonine-protein kinase PAK 12.7.11.10.447
3s1dZIRCytokinin dehydrogenase 11.5.99.120.447
3sf6FDAGlutaryl-CoA dehydrogenase/0.447
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.447
4ft5H2KSerine/threonine-protein kinase Chk12.7.11.10.447
4fw8NAI3-oxoacyl-(Acyl-carrier-protein) reductase/0.447
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.447
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.447
4y93746Tyrosine-protein kinase/0.447
2a1tFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.446
2hmaSAMtRNA-specific 2-thiouridylase MnmA/0.446
2itwITQEpidermal growth factor receptor2.7.10.10.446
2izsBRQCasein kinase I isoform gamma-32.7.11.10.446
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.446
3zh8C58Protein kinase C iota type2.7.11.130.446
4anqVGHALK tyrosine kinase receptor2.7.10.10.446
4dfn0K1Tyrosine-protein kinase SYK2.7.10.20.446
4ftm1HKSerine/threonine-protein kinase Chk12.7.11.10.446
1u5rATPSerine/threonine-protein kinase TAO22.7.11.10.445
2d8aNADL-threonine 3-dehydrogenase/0.445
3r83Z14Cyclin-dependent kinase 22.7.11.220.445
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.445
3vs3VSETyrosine-protein kinase HCK2.7.10.20.445
4fod0UVALK tyrosine kinase receptor2.7.10.10.445
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.445
4i0s1B5Tyrosine-protein kinase SYK2.7.10.20.445
4rqvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.445
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.444
1g2vTTPGlucose-1-phosphate thymidylyltransferase/0.444
2bfyH1NAurora kinase B-A2.7.11.10.444
2c6eHPMAurora kinase A2.7.11.10.444
2y05NAPProstaglandin reductase 1/0.444
3mdmFJZCholesterol 24-hydroxylase/0.444
3umoATPATP-dependent 6-phosphofructokinase isozyme 22.7.1.110.444
3vnhFUUKelch-like ECH-associated protein 1/0.444
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.444
4tuvCPZCytochrome P450 1191.140.444
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.444
1kzjCB3Thymidylate synthase/0.443
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.443
2xb5I7TTetracycline repressor protein class D/0.443
2xbjXBJSerine/threonine-protein kinase Chk22.7.11.10.443
2xp2VGHALK tyrosine kinase receptor2.7.10.10.443
2ylxFADPhenylacetone monooxygenase1.14.13.920.443
2zdt46CMitogen-activated protein kinase 102.7.11.240.443
3lj3WYEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
3mfuANPPeripheral plasma membrane protein CASK2.7.11.10.443
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.443
3orzBI43-phosphoinositide-dependent protein kinase 12.7.11.10.443
3q3cNADNAD-dependent L-serine dehydrogenase/0.443
4ansVGHALK tyrosine kinase receptor2.7.10.10.443
4ekl0RFRAC-alpha serine/threonine-protein kinase2.7.11.10.443
1q4l679Glycogen synthase kinase-3 beta2.7.11.260.442
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.442
2excJNKMitogen-activated protein kinase 102.7.11.240.442
2pe039Z3-phosphoinositide-dependent protein kinase 12.7.11.10.442
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.442
2qhn582Serine/threonine-protein kinase Chk12.7.11.10.442
2x9dITCTetracycline repressor protein class D/0.442
2ylzFADPhenylacetone monooxygenase1.14.13.920.442
3dt1P40Mitogen-activated protein kinase 14/0.442
3zm422TDual specificity mitogen-activated protein kinase kinase 12.7.12.20.442
4awiAQ2Mitogen-activated protein kinase 82.7.11.240.442
4bgg844Activin receptor type-12.7.11.300.442
4jqeANPCasein kinase II subunit alpha2.7.11.10.442
4k8aK8AFocal adhesion kinase 12.7.10.20.442
4oavACP2-5A-dependent ribonuclease3.1.260.442
4qmySTUSerine/threonine-protein kinase 242.7.11.10.442
1h1wATP3-phosphoinositide-dependent protein kinase 12.7.11.10.441
1nhhANPDNA mismatch repair protein MutL/0.441
1nzdUPGDNA beta-glucosyltransferase/0.441
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.441
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.441
3dogNNNCyclin-dependent kinase 22.7.11.220.441
3oqkS52Renin3.4.23.150.441
3pxkPXKFocal adhesion kinase 12.7.10.20.441
4ct2ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.441
4q71FADBifunctional protein PutA/0.441
4xf7ACPCarbohydrate/pyrimidine kinase, PfkB family/0.441
4yr9NADL-threonine 3-dehydrogenase, mitochondrial1.1.1.1030.441
1e8zSTUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
1fwkADPHomoserine kinase2.7.1.390.440
1fxsNAPGDP-L-fucose synthase/0.440
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.440
1qlhNADAlcohol dehydrogenase E chain1.1.1.10.440
1y0s331Peroxisome proliferator-activated receptor delta/0.440
2c0oL2GTyrosine-protein kinase HCK2.7.10.20.440
2cgu3A3Serine/threonine-protein kinase Chk12.7.11.10.440
2r5tANPSerine/threonine-protein kinase Sgk12.7.11.10.440
3fr8NDPKetol-acid reductoisomerase, chloroplastic1.1.1.860.440
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.440
3nbvANPKetohexokinase/0.440
3oibFDAPutative acyl-CoA dehydrogenase/0.440
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.440
3vs4VSFTyrosine-protein kinase HCK2.7.10.20.440
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.440
4e730NRMitogen-activated protein kinase 82.7.11.240.440
4ftn2HKSerine/threonine-protein kinase Chk12.7.11.10.440
4i6aHMG3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.880.440
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.440
4mf129YTyrosine-protein kinase ITK/TSK2.7.10.20.440
5jsfNAD17-beta-hydroxysteroid dehydrogenase 141.1.10.440