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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2qiqCYVReplicase polyprotein 1ab

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
2qiqCYVReplicase polyprotein 1ab/1.000
3v3m0ENReplicase polyprotein 1a3.4.19.120.551
2gz7D3FOrf1a polyprotein/0.507
2op9WR1Orf1ab polyprotein/0.482
2gz8F3FOrf1a polyprotein/0.478
2gtbAZPOrf1ab polyprotein/0.452
3ig6438Urokinase-type plasminogen activator3.4.21.730.451
2a5kAZPReplicase polyprotein 1ab3.4.220.448
5dp2NAPCurF/0.448
2vn1FK5Peptidylprolyl isomerase/0.442