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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2qhxFE1Pteridine reductase 11.5.1.33

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2qhxFE1Pteridine reductase 11.5.1.331.000
2bfaCB3Pteridine reductase 11.5.1.330.721
2bfpH4BPteridine reductase 11.5.1.330.636
1e92HBIPteridine reductase 11.5.1.330.621
2bf7HBIPteridine reductase 11.5.1.330.573
3h4vDVPPteridine reductase 11.5.1.330.565
2bfmTOPPteridine reductase 11.5.1.330.515
1p33MTXPteridine reductase 11.5.1.330.495
2vz0D64Pteridine reductase/0.442
4i6f1C7Serine/threonine-protein kinase PLK22.7.11.210.442