sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2q5o | TPW | Indole-3-pyruvate decarboxylase | 4.1.1.74 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2q5o | TPW | Indole-3-pyruvate decarboxylase | 4.1.1.74 | 1.000 | |
| 2q5q | TPW | Indole-3-pyruvate decarboxylase | 4.1.1.74 | 0.716 | |
| 4zp1 | TPP | Pyruvate decarboxylase | 4.1.1.1 | 0.591 | |
| 1y9d | TPP | Pyruvate oxidase | 1.2.3.3 | 0.542 | |
| 5ahk | TPP | Acetolactate synthase II, large subunit | / | 0.535 | |
| 2ihu | TP9 | N(2)-(2-carboxyethyl)arginine synthase | / | 0.533 | |
| 3ey9 | TDP | Pyruvate dehydrogenase [ubiquinone] | 1.2.5.1 | 0.531 | |
| 2pan | TDP | Glyoxylate carboligase | 4.1.1.47 | 0.525 | |
| 1upa | TPP | N(2)-(2-carboxyethyl)arginine synthase | / | 0.519 | |
| 2jlc | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.519 | |
| 5ej7 | TD6 | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.517 | |
| 5ej4 | TD6 | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.514 | |
| 1upb | TPP | N(2)-(2-carboxyethyl)arginine synthase | / | 0.508 | |
| 1upc | TPP | N(2)-(2-carboxyethyl)arginine synthase | / | 0.504 | |
| 1pyd | TDP | Pyruvate decarboxylase isozyme 1 | / | 0.503 | |
| 4k9o | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.503 | |
| 4k9n | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.501 | |
| 1mcz | TDP | Benzoylformate decarboxylase | 4.1.1.7 | 0.498 | |
| 2ag0 | TPP | Benzaldehyde lyase | / | 0.496 | |
| 4juf | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.496 | |
| 5ej9 | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.492 | |
| 1ozh | HE3 | Acetolactate synthase, catabolic | 2.2.1.6 | 0.491 | |
| 1ra3 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.490 | |
| 2ihv | TPP | N(2)-(2-carboxyethyl)arginine synthase | / | 0.489 | |
| 2jla | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.489 | |
| 2iht | TPP | N(2)-(2-carboxyethyl)arginine synthase | / | 0.488 | |
| 5eso | TDP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.488 | |
| 1ovm | TPP | Indole-3-pyruvate decarboxylase | 4.1.1.74 | 0.486 | |
| 2ag1 | TPP | Benzaldehyde lyase | / | 0.486 | |
| 3etg | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.485 | |
| 5eja | TD6 | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.484 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.483 | |
| 3stx | BKA | Methylketone synthase I | / | 0.480 | |
| 5esd | TDP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.479 | |
| 1pvd | TPP | Pyruvate decarboxylase isozyme 1 | / | 0.478 | |
| 2xpu | TDC | Tetracycline repressor protein class D | / | 0.478 | |
| 4jub | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.478 | |
| 2x7j | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.476 | |
| 2w93 | TPP | Pyruvate decarboxylase isozyme 1 | / | 0.469 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.469 | |
| 2uz1 | TPP | Benzaldehyde lyase | / | 0.467 | |
| 1hwz | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.465 | |
| 4k9p | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.465 | |
| 4y9q | C2E | Uncharacterized protein | / | 0.465 | |
| 2v3w | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.464 | |
| 5ej6 | TD6 | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.464 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.463 | |
| 2vk4 | TPP | Pyruvate decarboxylase | 4.1.1.1 | 0.463 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.463 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.463 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.462 | |
| 3cgf | JNF | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.461 | |
| 3ete | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.461 | |
| 3kyb | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.461 | |
| 3liv | E16 | Protease | / | 0.461 | |
| 4bid | IE8 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.461 | |
| 2b0m | 201 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.460 | |
| 3ih0 | ANP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.460 | |
| 5br7 | FAD | UDP-galactopyranose mutase | / | 0.460 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.459 | |
| 4i22 | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.459 | |
| 4z24 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.459 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.459 | |
| 1p0h | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.458 | |
| 1ysx | 4EB | Serum albumin | / | 0.458 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.458 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.458 | |
| 3oe1 | TDL | Pyruvate decarboxylase | 4.1.1.1 | 0.458 | |
| 4ks8 | B49 | Serine/threonine-protein kinase PAK 6 | 2.7.11.1 | 0.458 | |
| 4ly9 | 1YY | Glucokinase regulatory protein | / | 0.458 | |
| 2yir | YIR | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.457 | |
| 3w0y | DS4 | Vitamin D3 receptor | / | 0.457 | |
| 4jbq | VX6 | Aurora kinase A | 2.7.11.1 | 0.457 | |
| 4uyf | 73B | Bromodomain-containing protein 2 | / | 0.457 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.457 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.456 | |
| 1xq6 | NAP | Uncharacterized protein At5g02240 | / | 0.456 | |
| 1ybm | NAP | Uncharacterized protein At5g02240 | / | 0.456 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 3v8w | 0G2 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.456 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.456 | |
| 1lik | ADN | Adenosine kinase | 2.7.1.20 | 0.455 | |
| 1qpb | TPP | Pyruvate decarboxylase isozyme 1 | / | 0.455 | |
| 2b7a | IZA | Tyrosine-protein kinase JAK2 | / | 0.455 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 2qnq | QN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.455 | |
| 3ruk | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.455 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.455 | |
| 4dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 3a60 | STU | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.454 | |
| 3crl | ANP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.454 | |
| 5fs7 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.454 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.453 | |
| 1qvn | FRI | Interleukin-2 | / | 0.453 | |
| 3gbu | ATP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.453 | |
| 3ort | AGS | Serine/threonine protein kinase | / | 0.453 | |
| 3say | OFT | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.453 | |
| 3t3c | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.453 | |
| 4a6c | QG9 | Gag-Pol polyprotein | 3.4.23.16 | 0.453 | |
| 2bu8 | ADP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.452 | |
| 2ch6 | ADP | N-acetyl-D-glucosamine kinase | 2.7.1.59 | 0.452 | |
| 2o1x | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.452 | |
| 2v4l | ABJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.452 | |
| 2zl9 | VDA | Vitamin D3 receptor | / | 0.452 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.452 | |
| 3r7k | FDA | Probable acyl CoA dehydrogenase | / | 0.452 | |
| 4b8w | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.452 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.452 | |
| 4jlc | SU6 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.452 | |
| 4nh8 | 2LC | Heat shock protein HSP 90-alpha | / | 0.452 | |
| 4xcv | NDP | Probable hydroxyacid dehydrogenase protein | / | 0.452 | |
| 5k2a | ZMA | Adenosine receptor A2a | / | 0.452 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.451 | |
| 1uy7 | PU4 | Heat shock protein HSP 90-alpha | / | 0.451 | |
| 2fvl | NAP | Aldo-keto reductase family 1 member C4 | 1.1.1.225 | 0.451 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.451 | |
| 3el4 | ROC | Gag-Pol polyprotein | 3.4.23.16 | 0.451 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.451 | |
| 3lzu | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.451 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.451 | |
| 1qy5 | NEC | Endoplasmin | / | 0.450 | |
| 1uye | PU9 | Heat shock protein HSP 90-alpha | / | 0.450 | |
| 2cdu | FAD | NADH oxidase | / | 0.450 | |
| 2izr | BRK | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.450 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 2xb5 | I7T | Tetracycline repressor protein class D | / | 0.450 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.450 | |
| 3w0j | T08 | Vitamin D3 receptor | / | 0.450 | |
| 4jaz | STL | Peroxisome proliferator-activated receptor gamma | / | 0.450 | |
| 4o2b | LOC | Tubulin beta-2B chain | / | 0.450 | |
| 4xj4 | 3AT | Cyclic GMP-AMP synthase | / | 0.450 | |
| 4ydu | ADP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.450 | |
| 1glf | ADP | Glycerol kinase | / | 0.449 | |
| 1npv | L27 | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 1osv | CHC | Bile acid receptor | / | 0.449 | |
| 1rm5 | NDP | Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic | 1.2.1.13 | 0.449 | |
| 1xkv | ATP | Phosphoenolpyruvate carboxykinase (ATP) | / | 0.449 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.449 | |
| 3lq2 | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.449 | |
| 3p2e | SAH | 16S rRNA (adenine(1408)-N(1))-methyltransferase | 2.1.1.180 | 0.449 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.449 | |
| 4dqc | 017 | Gag-Pol polyprotein | / | 0.449 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 1ryi | FAD | Glycine oxidase | 1.4.3.19 | 0.448 | |
| 2o12 | FMN | Chorismate synthase | / | 0.448 | |
| 2qbn | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 2vna | NAP | Prostaglandin reductase 2 | 1.3.1.48 | 0.448 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.448 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.448 | |
| 4hjo | AQ4 | Epidermal growth factor receptor | 2.7.10.1 | 0.448 | |
| 4l8u | 9AZ | Serum albumin | / | 0.448 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.447 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.447 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.447 | |
| 1udy | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.447 | |
| 2b53 | D23 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 4b7d | QLE | Cytochrome P450 monooxygenase PikC | / | 0.447 | |
| 4l9k | EHF | Serum albumin | / | 0.447 | |
| 5bqf | NAP | Probable hydroxyacid dehydrogenase protein | / | 0.447 | |
| 5eai | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.447 | |
| 4z34 | ON7 | Lysophosphatidic acid receptor 1 | / | 0.447 | |
| 2qi4 | MZ6 | Gag-Pol polyprotein | / | 0.446 | |
| 2znp | K55 | Peroxisome proliferator-activated receptor delta | / | 0.446 | |
| 4b10 | NHW | Glycylpeptide N-tetradecanoyltransferase | / | 0.446 | |
| 4bdc | ODH | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.446 | |
| 4g21 | 0VP | Vitamin D3 receptor A | / | 0.446 | |
| 4gb2 | 0LQ | Gag-Pol polyprotein | 2.7.7.49 | 0.446 | |
| 5c88 | COA | N-alpha-acetyltransferase | / | 0.446 | |
| 1gle | ADP | Glycerol kinase | / | 0.445 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.445 | |
| 1pjk | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.445 | |
| 1trg | CB3 | Thymidylate synthase | / | 0.445 | |
| 2b9w | FAD | Putative aminooxidase | / | 0.445 | |
| 2q4b | NAP | Uncharacterized protein At5g02240 | / | 0.445 | |
| 3dmt | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.445 | |
| 3hwx | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.445 | |
| 3lki | ATP | Fructokinase | / | 0.445 | |
| 3v9y | 24L | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 4dqh | 017 | Gag-Pol polyprotein | / | 0.445 | |
| 4jvb | 1M0 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.445 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.445 | |
| 5dos | ATP | Aurora kinase A | 2.7.11.1 | 0.445 | |
| 5ej8 | TD6 | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.445 | |
| 5il2 | SAH | N6-adenosine-methyltransferase 70 kDa subunit | / | 0.445 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 1gii | 1PU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 1gjv | AGS | [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial | 2.7.11.4 | 0.444 | |
| 1q4t | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.444 | |
| 2e0a | ANP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | 2.7.11.2 | 0.444 | |
| 2fy4 | COA | Choline O-acetyltransferase | 2.3.1.6 | 0.444 | |
| 2j4z | 626 | Aurora kinase A | 2.7.11.1 | 0.444 | |
| 2ycf | YCF | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.444 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.444 | |
| 3bu5 | ATP | Insulin receptor | 2.7.10.1 | 0.444 | |
| 3d2p | COA | Amino-acid acetyltransferase | / | 0.444 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.444 | |
| 3pgp | ACO | Uncharacterized protein | / | 0.444 | |
| 3zuy | TCH | Transporter | / | 0.444 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.444 | |
| 4o70 | 1QK | Bromodomain-containing protein 4 | / | 0.444 | |
| 4ww0 | ADP | ATP-dependent zinc metalloprotease FtsH | / | 0.444 | |
| 1bsv | NDP | GDP-L-fucose synthase | / | 0.443 | |
| 1h1s | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 1hos | PHP | Gag-Pol polyprotein | / | 0.443 | |
| 1itz | TPP | Transketolase, chloroplastic | 2.2.1.1 | 0.443 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.443 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.443 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.443 | |
| 2c31 | TZD | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.443 | |
| 2q70 | DC8 | Estrogen receptor | / | 0.443 | |
| 2qi0 | MZ3 | Gag-Pol polyprotein | / | 0.443 | |
| 3c0i | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.443 | |
| 3lpb | NVB | Tyrosine-protein kinase JAK2 | / | 0.443 | |
| 3lu8 | IQX | Serum albumin | / | 0.443 | |
| 3r4p | FU7 | Heat shock protein HSP 90-alpha | / | 0.443 | |
| 4gyi | ADP | Uncharacterized protein | / | 0.443 | |
| 4ylf | FAD | Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit homolog | / | 0.443 | |
| 5c03 | AGS | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.443 | |
| 1glb | ADP | Glycerol kinase | / | 0.442 | |
| 1pr9 | NAP | L-xylulose reductase | 1.1.1.10 | 0.442 | |
| 1t85 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 1ykr | 628 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 2b9f | ADP | Mitogen-activated protein kinase FUS3 | 2.7.11.24 | 0.442 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.442 | |
| 2tps | TPS | Thiamine-phosphate synthase | / | 0.442 | |
| 3ec0 | GRL | Gag-Pol polyprotein | 3.4.23.47 | 0.442 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.442 | |
| 3qrw | NDP | Putative ketoacyl reductase | 1.3.1 | 0.442 | |
| 3t11 | 3T1 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 4ach | KDI | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.442 | |
| 4bgi | I4I | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 4ryv | ZEA | Protein LlR18A | / | 0.442 | |
| 4wbo | ANW | Rhodopsin kinase | / | 0.442 | |
| 1ae1 | NAP | Tropinone reductase 1 | / | 0.441 | |
| 1g4t | FTP | Thiamine-phosphate synthase | / | 0.441 | |
| 1ipe | NDP | Tropinone reductase 2 | 1.1.1.236 | 0.441 | |
| 1qxs | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.441 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.441 | |
| 1uyh | PU0 | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 2e9u | A25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 2h55 | DZ8 | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 2hc0 | AB2 | Protease | / | 0.441 | |
| 2q7v | FAD | Thioredoxin reductase | / | 0.441 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.441 | |
| 2y8q | ADP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.441 | |
| 2ycr | HCW | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.441 | |
| 2z6i | FMN | 2-nitropropane dioxygenase | / | 0.441 | |
| 3bbr | BHY | Glutamate receptor 2 | / | 0.441 | |
| 3bgb | LJG | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 3frq | ERY | Erythromycin resistance repressor protein | / | 0.441 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.441 | |
| 3ump | ATP | ATP-dependent 6-phosphofructokinase isozyme 2 | 2.7.1.11 | 0.441 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.441 | |
| 4e5y | NDP | GDP-L-fucose synthase | 1.1.1.271 | 0.441 | |
| 4fv9 | E71 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.441 | |
| 4hse | ADP | Chaperone protein ClpB | / | 0.441 | |
| 4ruj | VDX | Vitamin D3 receptor A | / | 0.441 | |
| 1dxo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 1eup | ASD | 6-deoxyerythronolide B hydroxylase | / | 0.440 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 1q5k | TMU | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.440 | |
| 2a1t | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.440 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.440 | |
| 2fto | CB3 | Thymidylate synthase | / | 0.440 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.440 | |
| 2itt | AEE | Epidermal growth factor receptor | 2.7.10.1 | 0.440 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 2jdv | L20 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.440 | |
| 2x3n | FAD | Probable FAD-dependent monooxygenase | / | 0.440 | |
| 3dk1 | G05 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 3ekt | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 3hrf | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.440 | |
| 3kgc | LY7 | Glutamate receptor 2 | / | 0.440 | |
| 3r2b | 05B | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.440 | |
| 3w0g | W07 | Vitamin D3 receptor | / | 0.440 | |
| 3zep | 1NX | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.440 | |
| 4aos | FAD | Steroid monooxygenase | / | 0.440 | |
| 4e37 | NDP | Catalase | 1.11.1.6 | 0.440 | |
| 4f9m | FCM | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 4fod | 0UV | ALK tyrosine kinase receptor | 2.7.10.1 | 0.440 | |
| 4hjf | C2E | GGDEF family protein | / | 0.440 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.440 |