scPDB - Distribution of Binding site Similarity values of 2q1l entry / Site 3

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
2q1l	882	3-hydroxy-3-methylglutaryl-coenzyme A reductase	1.1.1.34

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
2q1l	882	3-hydroxy-3-methylglutaryl-coenzyme A reductase	1.1.1.34	1.000
2r4f	RIE	3-hydroxy-3-methylglutaryl-coenzyme A reductase	1.1.1.34	0.635
2q6b	HR2	3-hydroxy-3-methylglutaryl-coenzyme A reductase	1.1.1.34	0.590
1dq9	HMG	3-hydroxy-3-methylglutaryl-coenzyme A reductase	1.1.1.34	0.557
3cd5	7HI	3-hydroxy-3-methylglutaryl-coenzyme A reductase	1.1.1.34	0.545
2q6c	HR1	3-hydroxy-3-methylglutaryl-coenzyme A reductase	1.1.1.34	0.527
1dq8	COA	3-hydroxy-3-methylglutaryl-coenzyme A reductase	1.1.1.34	0.481
3k3b	ADP	Kinesin-like protein KIF11	/	0.445
1ayl	ATP	Phosphoenolpyruvate carboxykinase (ATP)	/	0.440