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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2q0lFADThioredoxin reductase1.8.1.9

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2q0lFADThioredoxin reductase1.8.1.91.000
2q0kFADThioredoxin reductase1.8.1.90.596
3ishFADThioredoxin reductase1.8.1.90.506
4gcmFADThioredoxin reductase1.8.1.90.478
1cl0FADThioredoxin reductase1.8.1.90.473
4ccrFADThioredoxin reductase/0.460
1tdeFADThioredoxin reductase1.8.1.90.458
3s5wFADL-ornithine N(5)-monooxygenase/0.453
4ccqFADThioredoxin reductase/0.452
4jq9FADDihydrolipoyl dehydrogenase/0.447
3ctyFADProbable thioredoxin reductase/0.441