sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2pja | 33Z | Carboxypeptidase B |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2pja | 33Z | Carboxypeptidase B | / | 1.000 | |
| 2pj4 | 414 | Carboxypeptidase B | / | 0.610 | |
| 3fx6 | BPX | Carboxypeptidase A1 | 3.4.17.1 | 0.530 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.510 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.497 | |
| 2ag5 | NAD | 3-hydroxybutyrate dehydrogenase type 2 | / | 0.493 | |
| 3fvl | BHK | Carboxypeptidase A1 | 3.4.17.1 | 0.492 | |
| 3vyf | VYF | Renin | 3.4.23.15 | 0.490 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.488 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.488 | |
| 4dpi | 0N1 | Beta-secretase 1 | 3.4.23.46 | 0.486 | |
| 4opg | FDA | Conserved Archaeal protein | / | 0.485 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.481 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.481 | |
| 4exg | 916 | Beta-secretase 1 | 3.4.23.46 | 0.481 | |
| 3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.479 | |
| 1f8f | NAD | Benzyl alcohol dehydrogenase | / | 0.478 | |
| 3rpe | FAD | Putative modulator of drug activity | / | 0.478 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.478 | |
| 4eqs | FAD | Coenzyme A disulfide reductase | / | 0.478 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.476 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.476 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.476 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.475 | |
| 4lcj | NAD | C-terminal-binding protein 2 | / | 0.475 | |
| 2b3d | FAD | Modulator of drug activity B | / | 0.474 | |
| 4rvf | TYD | D-mycarose 3-C-methyltransferase | / | 0.474 | |
| 3vsx | R32 | Renin | 3.4.23.15 | 0.473 | |
| 4to2 | DGT | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.473 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.472 | |
| 4ewo | 996 | Beta-secretase 1 | 3.4.23.46 | 0.472 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.471 | |
| 1r6u | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.470 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.469 | |
| 1req | DCA | Methylmalonyl-CoA mutase large subunit | 5.4.99.2 | 0.468 | |
| 2ges | COK | Pantothenate kinase | 2.7.1.33 | 0.468 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.468 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.468 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.467 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.467 | |
| 3p84 | FMN | Pentaerythritol tetranitrate reductase | / | 0.467 | |
| 1nuu | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.466 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.466 | |
| 4awt | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.466 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.466 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.466 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.465 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.465 | |
| 2jk6 | FAD | Trypanothione reductase | / | 0.465 | |
| 2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.465 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.465 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.464 | |
| 2qs4 | LY5 | Glutamate receptor ionotropic, kainate 1 | / | 0.464 | |
| 3cos | NAD | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.464 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.463 | |
| 1yqz | FAD | Coenzyme A disulfide reductase | / | 0.463 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.463 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.463 | |
| 2j07 | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.463 | |
| 2j08 | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.463 | |
| 2trt | TAC | Tetracycline repressor protein class D | / | 0.463 | |
| 3lq4 | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.463 | |
| 4to4 | DCP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.463 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.463 | |
| 2c1z | U2F | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.462 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.462 | |
| 3zbr | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.462 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.461 | |
| 4bxk | 1IU | Angiotensin-converting enzyme | 3.2.1 | 0.461 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.460 | |
| 1typ | FAD | Trypanothione reductase | 1.8.1.12 | 0.460 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.460 | |
| 2w0h | FAD | Trypanothione reductase | / | 0.460 | |
| 2wf3 | ZY3 | Beta-secretase 1 | 3.4.23.46 | 0.460 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.459 | |
| 2zu8 | GDD | Mannosyl-3-phosphoglycerate synthase | 2.4.1.217 | 0.459 | |
| 3f63 | GTX | Glutathione transferase GST1-4 | / | 0.459 | |
| 3ov7 | ATP | CCA-adding enzyme | 2.7.7.72 | 0.459 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.459 | |
| 4die | C5P | Cytidylate kinase | / | 0.459 | |
| 4hmz | 18T | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.459 | |
| 4rxq | DUT | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.459 | |
| 1nhq | FAD | NADH peroxidase | 1.11.1.1 | 0.458 | |
| 3eks | CY9 | Actin-5C | / | 0.458 | |
| 3k5c | 0BI | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 3qdl | FMN | Oxygen-insensitive NADPH nitroreductase | / | 0.458 | |
| 3vsw | R31 | Renin | 3.4.23.15 | 0.458 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.458 | |
| 4eqw | FAD | Coenzyme A disulfide reductase | / | 0.458 | |
| 4yco | FMN | tRNA-dihydrouridine(16) synthase | / | 0.458 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.457 | |
| 1j21 | ATP | Argininosuccinate synthase | / | 0.457 | |
| 1pfy | MSP | Methionine--tRNA ligase | 6.1.1.10 | 0.457 | |
| 1rwb | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.457 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.457 | |
| 2f3r | G5P | Guanylate kinase | 2.7.4.8 | 0.457 | |
| 2o7o | DXT | Tetracycline repressor protein class D | / | 0.457 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.457 | |
| 4b63 | NAP | L-ornithine N(5)-monooxygenase | / | 0.457 | |
| 1bil | 0IU | Renin | 3.4.23.15 | 0.456 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.456 | |
| 3ivm | ZPR | Prolyl endopeptidase | / | 0.456 | |
| 3nsh | 957 | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 3vye | VYE | Renin | 3.4.23.15 | 0.456 | |
| 4em4 | FAD | Coenzyme A disulfide reductase | / | 0.456 | |
| 4frj | DWB | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 4i0i | 957 | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.455 | |
| 1het | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.455 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.455 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.455 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.455 | |
| 1j36 | LPR | Angiotensin-converting enzyme | 3.4.15.1 | 0.454 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.454 | |
| 2wf1 | ZY1 | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 2xve | FAD | Putative flavin-containing monooxygenase | / | 0.454 | |
| 3h0b | B35 | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 3vg1 | 0GT | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 4hb9 | FAD | Uncharacterized protein | / | 0.454 | |
| 1qrp | HH0 | Pepsin A-4 | 3.4.23.1 | 0.453 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.453 | |
| 2ome | NAD | C-terminal-binding protein 2 | / | 0.453 | |
| 3lpi | Z74 | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 3vf3 | 0GS | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 4eak | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.453 | |
| 4yxm | 2BA | DNA integrity scanning protein DisA | / | 0.453 | |
| 1n7h | NDP | GDP-mannose 4,6 dehydratase 2 | 4.2.1.47 | 0.452 | |
| 1x7h | NDP | Putative ketoacyl reductase | 1.3.1 | 0.452 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 2j09 | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.452 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.452 | |
| 2vpr | TDC | Tetracycline repressor protein class H | / | 0.452 | |
| 3aut | NAI | Glucose 1-dehydrogenase 4 | 1.1.1.47 | 0.452 | |
| 3p8j | FMN | Pentaerythritol tetranitrate reductase | / | 0.452 | |
| 4jld | ADP | Adenylate kinase | / | 0.452 | |
| 1np7 | FAD | Cryptochrome DASH | / | 0.451 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.451 | |
| 2nmt | MIM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.451 | |
| 3cib | 314 | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 4b79 | NAD | Probable short-chain dehydrogenase | / | 0.451 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.451 | |
| 4ohf | 5GP | Cytosolic IMP-GMP specific 5'-nucleotidase | / | 0.451 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.451 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.450 | |
| 1wm1 | PTB | Proline iminopeptidase | 3.4.11.5 | 0.450 | |
| 3hdq | GDU | UDP-galactopyranose mutase | / | 0.450 | |
| 3hy9 | 098 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.450 | |
| 3tr0 | 5GP | Guanylate kinase | / | 0.450 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.450 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.449 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.449 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.449 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.449 | |
| 3ukf | GDU | UDP-galactopyranose mutase | / | 0.449 | |
| 3v0p | 4GW | Histo-blood group ABO system transferase | / | 0.449 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.449 | |
| 4dy4 | FMN | NAD(P)H dehydrogenase (quinone) | / | 0.449 | |
| 4fco | 0U4 | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 1d4d | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.448 | |
| 1i2b | NAD | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.448 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.448 | |
| 1ylu | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.448 | |
| 1yqz | COA | Coenzyme A disulfide reductase | / | 0.448 | |
| 2b8l | 5HA | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 3f3s | NAD | Lambda-crystallin homolog | / | 0.448 | |
| 4gz6 | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.448 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.448 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.448 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.447 | |
| 1h6d | NDP | Glucose--fructose oxidoreductase | 1.1.99.28 | 0.447 | |
| 1vso | AT1 | Glutamate receptor ionotropic, kainate 1 | / | 0.447 | |
| 2oah | QIN | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 2x92 | X92 | Angiotensin-converting enzyme | 3.4.15.1 | 0.447 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.447 | |
| 3zgz | 84T | Leucine--tRNA ligase | / | 0.447 | |
| 4eb7 | PLP | Cysteine desulfurase IscS 2 | / | 0.447 | |
| 4ge9 | 0L0 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.447 | |
| 4kp7 | 1UQ | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic | 1.1.1.267 | 0.447 | |
| 1c7o | PPG | Hemolysin | / | 0.446 | |
| 1icv | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.446 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.446 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.446 | |
| 2ad5 | ADP | CTP synthase | / | 0.446 | |
| 2bjh | FER | Feruloyl esterase A | 3.1.1.73 | 0.446 | |
| 3a5y | KAA | Elongation factor P--(R)-beta-lysine ligase | / | 0.446 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.446 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.446 | |
| 3mt8 | 17T | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.446 | |
| 3pb3 | SAH | 16S rRNA (adenine(1408)-N(1))-methyltransferase | 2.1.1.180 | 0.446 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.446 | |
| 4ef8 | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.446 | |
| 4rxs | TTP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.446 | |
| 5a1t | NAI | L-lactate dehydrogenase | / | 0.446 | |
| 5b0o | ADP | Flagellum-specific ATP synthase | 3.6.3.14 | 0.446 | |
| 5er0 | FAD | Uncharacterized NAD(FAD)-dependent dehydrogenase | / | 0.446 | |
| 1orr | CDP | CDP-paratose 2-epimerase | / | 0.445 | |
| 2hm1 | LIQ | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.445 | |
| 3ean | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.445 | |
| 1fxs | NAP | GDP-L-fucose synthase | / | 0.444 | |
| 1kvk | ATP | Mevalonate kinase | 2.7.1.36 | 0.444 | |
| 1lf2 | R37 | Plasmepsin-2 | 3.4.23.39 | 0.444 | |
| 1r6t | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.444 | |
| 1rp7 | TZD | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.444 | |
| 2fbw | CBE | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | 1.3.5.1 | 0.444 | |
| 2fbw | CBE | Succinate dehydrogenase cytochrome b, large subunit | / | 0.444 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.444 | |
| 2is0 | I03 | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.444 | |
| 2ph6 | 712 | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 2xpw | OTC | Tetracycline repressor protein class D | / | 0.444 | |
| 2zru | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.444 | |
| 2zs9 | ADP | Pantothenate kinase | 2.7.1.33 | 0.444 | |
| 3fcc | ATP | D-alanine--poly(phosphoribitol) ligase subunit 1 | / | 0.444 | |
| 3img | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.444 | |
| 3kb6 | NAD | D-lactate dehydrogenase | / | 0.444 | |
| 3mjh | GTP | Ras-related protein Rab-5A | / | 0.444 | |
| 3nxq | RX4 | Angiotensin-converting enzyme | 3.2.1 | 0.444 | |
| 3qvp | FAD | Glucose oxidase | 1.1.3.4 | 0.444 | |
| 3u9e | COA | Lmo1369 protein | / | 0.444 | |
| 3uoy | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.444 | |
| 3up4 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.444 | |
| 3v2u | ATP | Protein GAL3 | / | 0.444 | |
| 4cf6 | CBD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 4dd8 | BAT | Disintegrin and metalloproteinase domain-containing protein 8 | 3.4.24 | 0.444 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.443 | |
| 1h6c | NDP | Glucose--fructose oxidoreductase | 1.1.99.28 | 0.443 | |
| 1kny | APC | Kanamycin nucleotidyltransferase | 2.7.7 | 0.443 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.443 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.443 | |
| 2h6i | CYS_VAL_LEU_SER_GER | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.443 | |
| 2vtt | LZD | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 3vkj | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.443 | |
| 3wwm | ADP | [LysW]-aminoadipate kinase | / | 0.443 | |
| 4a2z | VIQ | Glycylpeptide N-tetradecanoyltransferase | / | 0.443 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.443 | |
| 4gi5 | FAD | Putative NAD(P)H dehydrogenase (Quinone) | / | 0.443 | |
| 4i1i | NAD | Malate dehydrogenase | / | 0.443 | |
| 5e5h | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.443 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.442 | |
| 2zsa | ADP | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 3dm6 | 757 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 3g0b | T22 | Dipeptidyl peptidase 4 | / | 0.442 | |
| 3int | GDU | UDP-galactopyranose mutase | 5.4.99.9 | 0.442 | |
| 3own | 3OW | Renin | 3.4.23.15 | 0.442 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.442 | |
| 3zho | FMN | NAD(P)H dehydrogenase (quinone) | / | 0.442 | |
| 4itm | ATP | Tetraacyldisaccharide 4'-kinase | / | 0.442 | |
| 4qfz | TTP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.442 | |
| 4uth | FMN | Xenobiotic reductase | / | 0.442 | |
| 6req | 3CP | Methylmalonyl-CoA mutase large subunit | 5.4.99.2 | 0.442 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.441 | |
| 1kqo | DND | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.441 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.441 | |
| 1ylr | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.441 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.441 | |
| 2g5w | 8PG | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.441 | |
| 2gqa | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.441 | |
| 2ntr | L00 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 2vkv | TDC | Tetracycline repressor protein class D | / | 0.441 | |
| 2xy3 | DUP | SPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS | 3.6.1.23 | 0.441 | |
| 3iqi | ASN_GLU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.441 | |
| 3muo | ZPR | Prolyl endopeptidase | / | 0.441 | |
| 3qe2 | FMN | NADPH--cytochrome P450 reductase | / | 0.441 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
| 4ca8 | 3ES | Angiotensin-converting enzyme | 3.4.15.1 | 0.441 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.441 | |
| 4d89 | BXD | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4dja | FAD | (6-4) photolyase | / | 0.441 | |
| 4dna | FAD | Probable glutathione reductase | / | 0.441 | |
| 4gdc | NDP | UDP-galactopyranose mutase | / | 0.441 | |
| 4gdd | NAI | UDP-galactopyranose mutase | / | 0.441 | |
| 4j7h | TRH | PCZA361.3 | / | 0.441 | |
| 4mih | FAD | Pyranose 2-oxidase | 1.1.3.10 | 0.441 | |
| 4rxp | DTP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.441 | |
| 4yao | FMN | NADPH--cytochrome P450 reductase | / | 0.441 | |
| 1kw9 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.440 | |
| 1mj9 | COA | Histone acetyltransferase ESA1 | / | 0.440 | |
| 1s4p | GDP | Glycolipid 2-alpha-mannosyltransferase | / | 0.440 | |
| 2c12 | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.440 | |
| 2g21 | L1B | Renin | 3.4.23.15 | 0.440 | |
| 2g94 | ZPQ | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.440 | |
| 2ign | FAD | Pyranose 2-oxidase | / | 0.440 | |
| 2j4d | FAD | Cryptochrome DASH, chloroplastic/mitochondrial | / | 0.440 | |
| 2qbu | SAH | Precorrin-2 methyltransferase | / | 0.440 | |
| 2xyd | 3ES | Angiotensin-converting enzyme | 3.2.1 | 0.440 | |
| 2ztu | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.440 | |
| 3a3g | DLZ | Lumazine protein | / | 0.440 | |
| 3c8b | ARG_ARG_GLY_ILE_NH2 | Botulinum neurotoxin type A | 3.4.24.69 | 0.440 | |
| 3int | FDA | UDP-galactopyranose mutase | 5.4.99.9 | 0.440 | |
| 3k5f | AYH | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.440 | |
| 4aws | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.440 | |
| 4b2g | V1N | Uncharacterized protein | / | 0.440 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.440 | |
| 4j0v | 1H7 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4nes | UD1 | UDP-N-acetylglucosamine 2-epimerase | 5.1.3.14 | 0.440 | |
| 4tlz | NAP | KtzI | / | 0.440 | |
| 5fs7 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.440 | |
| 4u14 | 0HK | Muscarinic acetylcholine receptor M3 | / | 0.440 |