Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2pevNDPAldose reductase1.1.1.21

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2pevNDPAldose reductase1.1.1.211.000
2pf8NDPAldose reductase1.1.1.210.864
2iq0NAPAldose reductase1.1.1.210.695
1az2NAPAldose reductase1.1.1.210.673
2pfhNDPAldose reductase1.1.1.210.646
1z8aNAPAldose reductase1.1.1.210.644
2acqNAPAldose reductase1.1.1.210.637
2j8tNAPAldose reductase1.1.1.210.631
3q65NAPAldose reductase1.1.1.210.623
1ah4NAPAldose reductase1.1.1.210.620
1x98NAPAldose reductase1.1.1.210.615
2acuNAPAldose reductase1.1.1.210.613
3q67NAPAldose reductase1.1.1.210.605
3v36NAPAldose reductase1.1.1.210.605
3qkzNAPAldose reductase-related protein 11.1.1.210.600
1adsNAPAldose reductase1.1.1.210.599
3h7rNAPAldo-keto reductase family 4 member C8/0.586
2acsNAPAldose reductase1.1.1.210.575
1x96NAPAldose reductase1.1.1.210.573
1c9wNAPAldose reductase-related protein 2/0.569
1q5mNDPProstaglandin-E(2) 9-reductase1.1.1.1890.568
3h7uNAPNADPH-dependent aldo-keto reductase, chloroplastic/0.556
4pmjNAPPutative oxidoreductase/0.554
1k8cNAPNAD(P)H-dependent D-xylose reductase1.1.1.3070.538
3o3rNAPAldose reductase-related protein 11.1.1.210.538
3buvNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.534
2hejNDPAldo-keto reductase family 1 member C211.1.10.531
1mi3NADNAD(P)H-dependent D-xylose reductase1.1.1.3070.521
3wg6NDPNADPH-dependent conjugated polyketone reductase C1/0.518
1s1rNAPAldo-keto reductase family 1 member C3/0.516
3wbwNDPPutative 2,5-diketo-D-gluconic acid reductase/0.516
4dz5NAPAldo-keto reductase family 1 member C3/0.516
3uzwNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.514
4aubNAPL-glyceraldehyde 3-phosphate reductase1.1.10.513
4xo7NAPAldo-keto reductase family 1 member C2/0.512
1zgdNAPChalcone reductase/0.511
4g5dNDPProstaglandin F synthase1.1.1.1880.511
2p5nNDPAldo-keto reductase family 1 member C211.1.10.510
1lqaNDPProtein tas/0.508
4jtqNAPAldo-keto reductase family 1 member C2/0.506
5c7hNDPPutative oxidoreductase/0.505
2hdjNDPAldo-keto reductase family 1 member C2/0.503
3g1rNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.501
1r38NAPNAD(P)H-dependent D-xylose reductase1.1.1.3070.498
1vp5NAPOxidoreductase, aldo/keto reductase family/0.498
1ye6NADNAD(P)H-dependent D-xylose reductase1.1.1.3070.498
4l1xNAPAldo-keto reductase family 1 member C2/0.495
3wczNAPAldo-keto reductase AKR2E4/0.492
2fvlNAPAldo-keto reductase family 1 member C41.1.1.2250.489
1ye6NAPNAD(P)H-dependent D-xylose reductase1.1.1.3070.482
1ef3NAPAldose reductase1.1.1.210.478
3dopNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.478
4jtcNAPVoltage-gated potassium channel subunit beta-2/0.477
1z9aNADNAD(P)H-dependent D-xylose reductase1.1.1.3070.476
4jq3NAPAldo-keto reductase family 1 member C2/0.471
4xznNAPAldo-keto reductase family 1 member B101.1.10.471
4xzmNAPAldo-keto reductase family 1 member B101.1.10.470
1ye4NADNAD(P)H-dependent D-xylose reductase1.1.1.3070.467
3caqNDP3-oxo-5-beta-steroid 4-dehydrogenase/0.467
1a80NDP2,5-diketo-D-gluconic acid reductase A1.1.1.3460.466
4ijrNDPD-arabinose dehydrogenase [NAD(P)+] heavy chain1.1.1.1170.465
1sm9NADNAD(P)H-dependent D-xylose reductase1.1.1.3070.463
2r9rNAPVoltage-gated potassium channel subunit beta-2/0.460
1og6NAPOxidoreductase YdhF10.459
2vdgNDPAldose reductase1.1.1.210.459
3bv7NAP3-oxo-5-beta-steroid 4-dehydrogenase/0.454
1pz1NAPGeneral stress protein 69/0.452
3lnmNAPVoltage-gated potassium channel subunit beta-2/0.451
1lwiNAP3-alpha-hydroxysteroid dehydrogenase1.1.1.500.447