Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
PDB ID | HET | Uniprot Name | EC Number |
---|---|---|---|
2pd9 | FID | Aldose reductase | 1.1.1.21 |
PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
---|---|---|---|---|---|
2pd9 | FID | Aldose reductase | 1.1.1.21 | 1.000 | |
2agt | FID | Aldose reductase | 1.1.1.21 | 0.720 | |
2pdw | FID | Aldose reductase | 1.1.1.21 | 0.699 | |
2is7 | 2CL | Aldose reductase | 1.1.1.21 | 0.681 | |
2pdk | SBI | Aldose reductase | 1.1.1.21 | 0.655 | |
1ef3 | FID | Aldose reductase | 1.1.1.21 | 0.645 | |
1eko | I84 | Aldose reductase | 1.1.1.21 | 0.639 | |
2f2k | TGG | Aldose reductase | 1.1.1.21 | 0.638 | |
2pdy | FID | Aldose reductase | 1.1.1.21 | 0.624 | |
3p2v | DOY | Aldose reductase | 1.1.1.21 | 0.616 | |
1pwm | FID | Aldose reductase | 1.1.1.21 | 0.612 | |
2nvc | ITA | Aldose reductase | 1.1.1.21 | 0.599 | |
4gab | FID | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.597 | |
3v35 | NTI | Aldose reductase | 1.1.1.21 | 0.596 | |
3s3g | TLT | Aldose reductase | 1.1.1.21 | 0.594 | |
1zua | TOL | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.586 | |
3u2c | SUZ | Aldose reductase | 1.1.1.21 | 0.585 | |
2pdj | 393 | Aldose reductase | 1.1.1.21 | 0.582 | |
5liu | 388 | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.581 | |
1ah0 | SBI | Aldose reductase | 1.1.1.21 | 0.566 | |
2fzd | TOL | Aldose reductase | 1.1.1.21 | 0.558 | |
2inz | OHP | Aldose reductase | 1.1.1.21 | 0.558 | |
2pdu | 393 | Aldose reductase | 1.1.1.21 | 0.553 | |
1el3 | I84 | Aldose reductase | 1.1.1.21 | 0.550 | |
3m4h | 388 | Aldose reductase | 1.1.1.21 | 0.547 | |
2fzb | TOL | Aldose reductase | 1.1.1.21 | 0.543 | |
4wev | SUZ | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.537 | |
3lql | LDT | Aldose reductase | 1.1.1.21 | 0.534 | |
3lz5 | LDT | Aldose reductase | 1.1.1.21 | 0.534 | |
3ght | LDT | Aldose reductase | 1.1.1.21 | 0.529 | |
4i9z | 5BA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.528 | |
3wav | DWV | Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 | 3.1.4.39 | 0.525 | |
3h4g | FID | Alcohol dehydrogenase [NADP(+)] | 1.1.1.2 | 0.523 | |
4gca | 2X9 | Aldose reductase | 1.1.1.21 | 0.521 | |
2vrj | NCW | Beta-glucosidase A | 3.2.1.21 | 0.520 | |
1uho | VDN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.519 | |
2ikj | 393 | Aldose reductase | 1.1.1.21 | 0.519 | |
2pdl | TOL | Aldose reductase | 1.1.1.21 | 0.517 | |
1az1 | ALR | Aldose reductase | 1.1.1.21 | 0.513 | |
2iqd | LPA | Aldose reductase | 1.1.1.21 | 0.511 | |
1zq5 | E04 | Aldo-keto reductase family 1 member C3 | / | 0.510 | |
4pab | THG | Dimethylglycine dehydrogenase, mitochondrial | 1.5.8.4 | 0.509 | |
2hv5 | ZST | Aldose reductase | 1.1.1.21 | 0.508 | |
2iki | 388 | Aldose reductase | 1.1.1.21 | 0.508 | |
1t41 | ID5 | Aldose reductase | 1.1.1.21 | 0.505 | |
2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.505 | |
4oew | 5IO | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.503 | |
4paa | THG | Dimethylglycine dehydrogenase, mitochondrial | 1.5.8.4 | 0.503 | |
4g2w | NI0 | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.502 | |
1us0 | LDT | Aldose reductase | 1.1.1.21 | 0.501 | |
2ipw | 2CL | Aldose reductase | 1.1.1.21 | 0.500 | |
2hvn | ZST | Aldose reductase | 1.1.1.21 | 0.499 | |
3lbo | LDT | Aldose reductase | 1.1.1.21 | 0.499 | |
1xor | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.498 | |
2pdx | ZST | Aldose reductase | 1.1.1.21 | 0.498 | |
1isg | AGS | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 | 3.2.2.6 | 0.496 | |
1tfz | 869 | 4-hydroxyphenylpyruvate dioxygenase | 1.13.11.27 | 0.493 | |
8cat | NDP | Catalase | 1.11.1.6 | 0.493 | |
1ry0 | PG2 | Aldo-keto reductase family 1 member C3 | / | 0.492 | |
2dux | ZST | Aldose reductase | 1.1.1.21 | 0.492 | |
4oex | 5EO | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.491 | |
1e1f | PSG | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic | 3.2.1.182 | 0.489 | |
3qeo | LLT | Deoxycytidine kinase | 2.7.1.74 | 0.489 | |
4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.489 | |
4gts | 7TP | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.489 | |
1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.488 | |
4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.488 | |
1tbb | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.487 | |
3f3y | 4OA | Bile salt sulfotransferase | 2.8.2.14 | 0.487 | |
3uzz | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.487 | |
3w5e | NVW | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.486 | |
3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.486 | |
1rxj | BNI | Streptavidin | / | 0.485 | |
2pdf | ZST | Aldose reductase | 1.1.1.21 | 0.485 | |
4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.485 | |
4xwt | U5P | Ribonuclease J | / | 0.485 | |
2pdc | 393 | Aldose reductase | 1.1.1.21 | 0.484 | |
2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.484 | |
3aiv | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic | 3.2.1.182 | 0.484 | |
4fam | 0SZ | Aldo-keto reductase family 1 member C3 | / | 0.484 | |
4g2y | NI5 | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.484 | |
4llk | MEW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.483 | |
1z89 | 62P | Aldose reductase | 1.1.1.21 | 0.482 | |
2f38 | 15M | Aldo-keto reductase family 1 member C3 | / | 0.481 | |
2h44 | 7CA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.481 | |
1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.480 | |
5dsy | UHB | Poly [ADP-ribose] polymerase 2 | 2.4.2.30 | 0.480 | |
4blc | NDP | Catalase | 1.11.1.6 | 0.479 | |
4h7c | 10H | Aldo-keto reductase family 1 member C3 | / | 0.479 | |
1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.478 | |
2w3m | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.478 | |
3pz3 | PZ3 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.478 | |
1dlr | MXA | Dihydrofolate reductase | 1.5.1.3 | 0.477 | |
1pax | DHQ | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.477 | |
3r7m | SUZ | Aldo-keto reductase family 1 member C3 | / | 0.477 | |
1ycg | FMN | Nitric oxide reductase | 1 | 0.476 | |
3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.476 | |
3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.476 | |
4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.476 | |
1upw | 444 | Oxysterols receptor LXR-beta | / | 0.475 | |
2f98 | NGV | Aklanonic acid methyl ester cyclase AcmA | 5.5.1.23 | 0.475 | |
4zzi | 1NS | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.475 | |
2hzq | STR | Apolipoprotein D | / | 0.474 | |
2o8h | 227 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.474 | |
3c49 | KU8 | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.474 | |
3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.474 | |
4dbs | 0HV | Aldo-keto reductase family 1 member C3 | / | 0.474 | |
1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.473 | |
1zz1 | SHH | Histone deacetylase-like amidohydrolase | 3.5.1 | 0.473 | |
3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.473 | |
1dls | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.472 | |
1y2b | DEE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.472 | |
2toh | HBI | Tyrosine 3-monooxygenase | 1.14.16.2 | 0.472 | |
4tvj | 09L | Poly [ADP-ribose] polymerase 2 | 2.4.2.30 | 0.472 | |
3d3p | 20A | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.471 | |
3dr7 | GPD | GDP-perosamine synthase | / | 0.471 | |
1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.470 | |
1hfr | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
1kms | LIH | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
2aj4 | ANP | Galactokinase | 2.7.1.6 | 0.470 | |
2ipi | AKY | Aclacinomycin-N/aclacinomycin-A oxidase | / | 0.470 | |
2r6j | NDP | Eugenol synthase 1 | 1.1.1.318 | 0.470 | |
4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.470 | |
4hhz | 15S | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.470 | |
1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.469 | |
1w29 | TS1 | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.469 | |
1x8l | OXR | Retinol dehydratase | / | 0.469 | |
2vdy | HCY | Corticosteroid-binding globulin | / | 0.469 | |
3fx4 | FX4 | Alcohol dehydrogenase [NADP(+)] | 1.1.1.2 | 0.469 | |
1dgb | NDP | Catalase | 1.11.1.6 | 0.468 | |
1udt | VIA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.468 | |
3g5e | Q74 | Aldose reductase | 1.1.1.21 | 0.468 | |
4dbw | 511 | Aldo-keto reductase family 1 member C3 | / | 0.468 | |
1ut6 | A8N | Acetylcholinesterase | 3.1.1.7 | 0.467 | |
2acl | L05 | Oxysterols receptor LXR-alpha | / | 0.467 | |
2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.467 | |
2xi4 | AFT | Acetylcholinesterase | 3.1.1.7 | 0.467 | |
3cv7 | C2U | Alcohol dehydrogenase [NADP(+)] | 1.1.1.2 | 0.467 | |
3r8g | IZP | Aldo-keto reductase family 1 member C3 | / | 0.467 | |
4ia0 | 5BB | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.467 | |
1kyy | INI | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.466 | |
1oyn | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.466 | |
1pwl | BFI | Aldose reductase | 1.1.1.21 | 0.466 | |
1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.466 | |
3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.466 | |
1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.465 | |
1ry8 | RUT | Aldo-keto reductase family 1 member C3 | / | 0.465 | |
1v3q | 2DI | Purine nucleoside phosphorylase | 2.4.2.1 | 0.465 | |
1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.465 | |
2b8j | ADN | Class B acid phosphatase | 3.1.3.2 | 0.465 | |
2e94 | 364 | Geranylgeranyl pyrophosphate synthase | / | 0.465 | |
3cas | ASD | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.465 | |
3g4k | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.465 | |
3nub | UD0 | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.465 | |
3r6i | JMS | Aldo-keto reductase family 1 member C3 | / | 0.465 | |
3u57 | DH8 | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.465 | |
3v94 | WYQ | Phosphodiesterase | / | 0.465 | |
4ajg | F07 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.465 | |
4li6 | 1XO | Tankyrase-1 | 2.4.2.30 | 0.465 | |
4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.465 | |
1s36 | CEI | Obelin | / | 0.464 | |
1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.464 | |
2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.464 | |
3cui | X4S | Exoglucanase/xylanase | 3.2.1.91 | 0.464 | |
3nn6 | HNK | 6-hydroxy-L-nicotine oxidase | / | 0.464 | |
3nu0 | 3TU | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
4ckr | DI1 | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.464 | |
4i5x | FLF | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.464 | |
1p91 | SAM | 23S rRNA (guanine(745)-N(1))-methyltransferase | / | 0.463 | |
1w19 | T1P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.463 | |
1zgc | A2E | Acetylcholinesterase | 3.1.1.7 | 0.463 | |
2a8g | GNG | Avidin | / | 0.463 | |
2vi5 | Y19 | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.463 | |
2xuf | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.463 | |
3i9k | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase | 3.2.2.6 | 0.463 | |
3qpo | PFR | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.463 | |
3uyk | 0CX | Probable NDP-rhamnosyltransferase | / | 0.463 | |
1kyv | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.462 | |
1odn | APV | Isopenicillin N synthase | 1.21.3.1 | 0.462 | |
2bjs | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.462 | |
2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.462 | |
2pdp | 393 | Aldose reductase | 1.1.1.21 | 0.462 | |
3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.462 | |
3zj7 | C1K | Strictosidine-O-beta-D-glucosidase | 3.2.1.105 | 0.462 | |
7cat | NDP | Catalase | 1.11.1.6 | 0.462 | |
1dgf | NDP | Catalase | 1.11.1.6 | 0.461 | |
1pq6 | 965 | Oxysterols receptor LXR-beta | / | 0.461 | |
1xf0 | ASD | Aldo-keto reductase family 1 member C3 | / | 0.461 | |
2pdb | ZST | Aldose reductase | 1.1.1.21 | 0.461 | |
2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.461 | |
4dbu | BT9 | Aldo-keto reductase family 1 member C3 | / | 0.461 | |
4jpg | 1OX | Pyruvate kinase PKM | 2.7.1.40 | 0.461 | |
4kn1 | 04J | Folate receptor beta | / | 0.461 | |
4mvh | 2F5 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.461 | |
1lel | BH7 | Avidin | / | 0.460 | |
1s9d | AFB | Cytohesin-2 | / | 0.460 | |
1s9d | AFB | ADP-ribosylation factor 1 | / | 0.460 | |
2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
2jf6 | S55 | Strictosidine-O-beta-D-glucosidase | 3.2.1.105 | 0.460 | |
2pdh | 47D | Aldose reductase | 1.1.1.21 | 0.460 | |
1drf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
1nqu | RDL | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.459 | |
2gyw | OBI | Acetylcholinesterase | 3.1.1.7 | 0.459 | |
2pb1 | NFG | Glucan 1,3-beta-glucosidase | / | 0.459 | |
2pd5 | ZST | Aldose reductase | 1.1.1.21 | 0.459 | |
2q0g | UPU | Poly(A) polymerase, putative | / | 0.459 | |
2wsa | 646 | Glycylpeptide N-tetradecanoyltransferase | / | 0.459 | |
3u5y | SCG | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.459 | |
4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.459 | |
4ajm | 3A6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.459 | |
4jq3 | ZOM | Aldo-keto reductase family 1 member C2 | / | 0.459 | |
4keb | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
4kq6 | DLZ | 6,7-dimethyl-8-ribityllumazine synthase | / | 0.459 | |
5agk | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.459 | |
1d3d | BZT | Prothrombin | 3.4.21.5 | 0.458 | |
1gt5 | BZQ | Odorant-binding protein | / | 0.458 | |
1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.458 | |
2ha6 | SCK | Acetylcholinesterase | 3.1.1.7 | 0.458 | |
2qg4 | UGA | UDP-glucose 6-dehydrogenase | 1.1.1.22 | 0.458 | |
3bur | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.458 | |
3m0i | ZST | Aldose reductase | 1.1.1.21 | 0.458 | |
4m6k | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
5cxv | 0HK | Muscarinic acetylcholine receptor M1 | / | 0.458 | |
1q9m | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.457 | |
2fzj | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
2oaz | I96 | Methionine aminopeptidase 2 | / | 0.457 | |
3sl6 | JN8 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.457 | |
4n3l | 2FN | Prothrombin | 3.4.21.5 | 0.457 | |
4yu1 | 53N | Aldose reductase | 1.1.1.21 | 0.457 | |
1dgg | NDP | Catalase | 1.11.1.6 | 0.456 | |
1m67 | BOA | Glycerol-3-phosphate dehydrogenase [NAD(+)], glycosomal | 1.1.1.8 | 0.456 | |
1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
1t13 | INI | 6,7-dimethyl-8-ribityllumazine synthase 2 | / | 0.456 | |
1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.456 | |
1xoq | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.456 | |
2cle | F6F | Tryptophan synthase alpha chain | / | 0.456 | |
2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
4bjb | P34 | Tankyrase-2 | 2.4.2.30 | 0.456 | |
1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
1kw9 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.455 | |
2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.455 | |
2gmv | UN8 | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | 4.1.1.32 | 0.455 | |
2vqq | TFG | Histone deacetylase 4 | 3.5.1.98 | 0.455 | |
2xlt | NA0 | Putative flavin-containing monooxygenase | / | 0.455 | |
3hxe | BD8 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.455 | |
3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
3qfr | FAD | NADPH--cytochrome P450 reductase | / | 0.455 | |
3std | MQ0 | Scytalone dehydratase | 4.2.1.94 | 0.455 | |
4jqa | ID8 | Aldo-keto reductase family 1 member C2 | / | 0.455 | |
4muw | 2F4 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.455 | |
5epv | ACP | Blue-light-activated histidine kinase | 2.7.13.3 | 0.455 | |
1enp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic | 1.3.1.9 | 0.454 | |
2pdn | 47D | Aldose reductase | 1.1.1.21 | 0.454 | |
2po3 | T4K | 4-dehydrase | / | 0.454 | |
3ug8 | IMN | Aldo-keto reductase family 1 member C3 | / | 0.454 | |
3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
4ajd | F04 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.454 | |
4ddl | 0JQ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.454 | |
1ohj | COP | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
2f99 | AKV | Aklanonic acid methyl ester cyclase AcmA | 5.5.1.23 | 0.453 | |
2ikh | LIT | Aldose reductase | 1.1.1.21 | 0.453 | |
2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
3c3d | FO1 | 2-phospho-L-lactate transferase | / | 0.453 | |
3caq | NDP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.453 | |
3gyf | 51P | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
3k7t | FAD | 6-hydroxy-L-nicotine oxidase | / | 0.453 | |
3len | ZST | Aldose reductase | 1.1.1.21 | 0.453 | |
3mb9 | ZST | Aldose reductase | 1.1.1.21 | 0.453 | |
3wi2 | P98 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.453 | |
4lm4 | JPZ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.453 | |
5a4v | QUE | Glutathione S-transferase F2 | 2.5.1.18 | 0.453 | |
4mqt | 2CU | Muscarinic acetylcholine receptor M2 | / | 0.453 | |
1dgh | NDP | Catalase | 1.11.1.6 | 0.452 | |
1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.452 | |
1lnm | DTX | Bilin-binding protein | / | 0.452 | |
1t40 | ID5 | Aldose reductase | 1.1.1.21 | 0.452 | |
2zhe | 13U | Prothrombin | 3.4.21.5 | 0.452 | |
2zs9 | ADP | Pantothenate kinase | 2.7.1.33 | 0.452 | |
3nxt | D2E | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
5cc9 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
1re0 | AFB | ADP-ribosylation factor 1 | / | 0.451 | |
1re0 | AFB | ARF guanine-nucleotide exchange factor 1 | / | 0.451 | |
1vot | HUP | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
1w19 | T4P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.451 | |
1y2d | 4DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.451 | |
1zgv | 501 | Prothrombin | 3.4.21.5 | 0.451 | |
2fb8 | 215 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.451 | |
2gvc | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.451 | |
2ovv | PFH | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.451 | |
2pdm | ZST | Aldose reductase | 1.1.1.21 | 0.451 | |
2r7n | ADP | 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase | / | 0.451 | |
2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
3r8h | ZOM | Aldo-keto reductase family 1 member C3 | / | 0.451 | |
4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.451 | |
4dyp | 0MS | Nucleoprotein | / | 0.451 | |
4kfj | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
2rh1 | CAU | Beta-2 adrenergic receptor | / | 0.451 | |
1efy | BZC | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.450 | |
1fml | RTL | Retinol dehydratase | / | 0.450 | |
1z5u | CMP | Class B acid phosphatase | / | 0.450 | |
2hvo | ZST | Aldose reductase | 1.1.1.21 | 0.450 | |
2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.450 | |
2ouy | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.450 | |
2rd6 | 78P | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.450 | |
3rl4 | 5GP | Metallophosphoesterase MPPED2 | 3.1 | 0.450 | |
3ugr | IMN | Aldo-keto reductase family 1 member C3 | / | 0.450 | |
4heu | 15J | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.450 | |
4jtq | FLP | Aldo-keto reductase family 1 member C2 | / | 0.450 | |
1ro6 | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.449 | |
1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.449 | |
2vqo | TFG | Histone deacetylase 4 | 3.5.1.98 | 0.449 | |
3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.449 | |
3djl | FAD | Putative acyl-CoA dehydrogenase AidB | 1.3.99 | 0.449 | |
3iak | EV1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.449 | |
3nwl | NDP | Catalase | 1.11.1.6 | 0.449 | |
3uzx | AOM | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.449 | |
1gm8 | SOX | Penicillin G acylase | 3.5.1.11 | 0.448 | |
1rkw | PNT | HTH-type transcriptional regulator QacR | / | 0.448 | |
2fjm | 073 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.448 | |
2jl1 | NAP | Triphenylmethane reductase | / | 0.448 | |
2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
3ai0 | PNW | Beta-glucosidase | / | 0.448 | |
3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
3fzn | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.448 | |
3ghu | LDT | Aldose reductase | 1.1.1.21 | 0.448 | |
3vf6 | 0H6 | Glucokinase | 2.7.1.2 | 0.448 | |
4fcb | 0T7 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.448 | |
4qa0 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.448 | |
5cto | NTD | 4-hydroxyphenylpyruvate dioxygenase | 1.13.11.27 | 0.448 | |
5a8e | XTK | Beta-1 adrenergic receptor | / | 0.448 | |
1d3p | BT3 | Prothrombin | 3.4.21.5 | 0.447 | |
1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.447 | |
1oyt | FSN | Prothrombin | 3.4.21.5 | 0.447 | |
1p8d | CO1 | Oxysterols receptor LXR-beta | / | 0.447 | |
1v08 | NTZ | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic | 3.2.1.182 | 0.447 | |
1ygj | RMC | Pyridoxal kinase | 2.7.1.35 | 0.447 | |
2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.447 | |
2c94 | TSF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.447 | |
3khu | UPG | UDP-glucose 6-dehydrogenase | 1.1.1.22 | 0.447 | |
3sl8 | JN7 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.447 | |
4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.447 | |
4dyn | 0MR | Nucleoprotein | / | 0.447 | |
4hf4 | 15H | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.447 | |
4ts7 | ADP | Purine phosphoribosyltransferase (GpT-1) | / | 0.447 | |
4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.447 | |
1d6w | 00R | Prothrombin | 3.4.21.5 | 0.446 | |
1sg0 | STL | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.446 | |
1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
1vkg | CRI | Histone deacetylase 8 | 3.5.1.98 | 0.446 | |
1zkn | IBM | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.446 | |
2bdy | UNB | Prothrombin | 3.4.21.5 | 0.446 | |
2ipj | FFA | Aldo-keto reductase family 1 member C2 | / | 0.446 | |
2qcx | PF1 | Aminopyrimidine aminohydrolase | / | 0.446 | |
2xug | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
2y0j | AXC | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.446 | |
3buv | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.446 | |
3ojx | FAD | NADPH--cytochrome P450 reductase | / | 0.446 | |
4bb2 | STR | Corticosteroid-binding globulin | / | 0.446 | |
4hhy | 15R | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.446 | |
1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
1fxu | GU7 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.445 | |
1s2c | FLF | Aldo-keto reductase family 1 member C3 | / | 0.445 | |
1z3n | 3NA | Aldose reductase | 1.1.1.21 | 0.445 | |
2cf9 | 348 | Prothrombin | 3.4.21.5 | 0.445 | |
2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.445 | |
2gl0 | ADN | Uncharacterized protein | / | 0.445 | |
2wnb | C5P | CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 | 2.4.99.4 | 0.445 | |
2xuk | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
3l3r | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
4drh | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.445 | |
4drh | RAP | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.445 | |
1jf0 | CZH | Obelin | / | 0.444 | |
1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.444 | |
1s3w | TQT | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.444 | |
2dv0 | ZST | Aldose reductase | 1.1.1.21 | 0.444 | |
2i16 | LDT | Aldose reductase | 1.1.1.21 | 0.444 | |
2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.444 | |
2pdi | ZST | Aldose reductase | 1.1.1.21 | 0.444 | |
2qjp | ANJ | Cytochrome b | / | 0.444 | |
2wu4 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
3aiq | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1b, chloroplastic | 3.2.1.182 | 0.444 | |
3c1o | NAP | Eugenol synthase | / | 0.444 | |
3cr0 | 809 | Wee1-like protein kinase | 2.7.10.2 | 0.444 | |
3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.444 | |
3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.444 | |
4a16 | H34 | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
4c2z | 646 | Glycylpeptide N-tetradecanoyltransferase 1 | / | 0.444 | |
4phl | PIL | Phosphodiesterase | / | 0.444 | |
4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.444 | |
1q83 | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
1w76 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
1z71 | L17 | Prothrombin | 3.4.21.5 | 0.443 | |
1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.443 | |
2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
2xuh | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
3b9g | IMH | IAG-nucleoside hydrolase | / | 0.443 | |
3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.443 | |
3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
3ghr | LDT | Aldose reductase | 1.1.1.21 | 0.443 | |
3gi2 | GHW | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
3gwf | FAD | Cyclohexanone monooxygenase | / | 0.443 | |
3iu9 | T07 | Methionine aminopeptidase 2 | / | 0.443 | |
3m64 | 393 | Aldose reductase | 1.1.1.21 | 0.443 | |
3o73 | O73 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.443 | |
3pn1 | IVH | DNA ligase | / | 0.443 | |
3qpn | PFK | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.443 | |
3tfu | PL8 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.443 | |
3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.443 | |
4af7 | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.443 | |
4ajf | F03 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.443 | |
4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
4drj | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.443 | |
4drj | RAP | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.443 | |
4ky4 | 04J | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.443 | |
4yfy | 0FX | VioF | / | 0.443 | |
2y04 | 68H | Beta-1 adrenergic receptor | / | 0.443 | |
1frb | ZST | Aldose reductase-related protein 2 | / | 0.442 | |
1ja1 | FMN | NADPH--cytochrome P450 reductase | / | 0.442 | |
1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
1w4l | GL8 | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
2bd0 | BIO | Sepiapterin reductase | / | 0.442 | |
2puc | GUN | HTH-type transcriptional repressor PurR | / | 0.442 | |
3af0 | GDP | Pantothenate kinase | 2.7.1.33 | 0.442 | |
3b8x | G4M | Putative pyridoxamine 5-phosphate-dependent dehydrase | / | 0.442 | |
3d2d | REN | Reticuline oxidase | 1.21.3.3 | 0.442 | |
3g58 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
3hbf | MYC | Flavonoid 3-O-glucosyltransferase | 2.4.1 | 0.442 | |
3up3 | XCA | aceDAF-12 | / | 0.442 | |
4gv2 | 5ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.442 | |
4hh4 | SAH | CcbJ | / | 0.442 | |
4jvm | XDI | Estrogen sulfotransferase | 2.8.2.4 | 0.442 | |
4kn0 | MTX | Folate receptor beta | / | 0.442 | |
1nqv | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.441 | |
1std | BFS | Scytalone dehydratase | 4.2.1.94 | 0.441 | |
2get | COK | Pantothenate kinase | 2.7.1.33 | 0.441 | |
2ovy | PFJ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
2vq3 | NAP | Metalloreductase STEAP3 | / | 0.441 | |
2ycw | CAU | Beta-1 adrenergic receptor | / | 0.441 | |
2zc9 | 22U | Prothrombin | 3.4.21.5 | 0.441 | |
3mjr | AC2 | Deoxycytidine kinase | 2.7.1.74 | 0.441 | |
3uzx | AOX | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.441 | |
4b77 | 54M | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
4bvh | OCZ | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.441 | |
4c1i | EH9 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.441 | |
4fal | 0T0 | Aldo-keto reductase family 1 member C3 | / | 0.441 | |
4gi4 | 0EX | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.441 | |
4kxj | P34 | Nucleoprotein | / | 0.441 | |
1mdt | APU | Diphtheria toxin | / | 0.440 | |
1nce | CB3 | Thymidylate synthase | / | 0.440 | |
1yhj | R6C | Pyridoxal kinase | 2.7.1.35 | 0.440 | |
1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.440 | |
2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.440 | |
2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.440 | |
2c9z | QUE | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.440 | |
2iuz | D1H | Endochitinase B1 | 3.2.1.14 | 0.440 | |
2oac | GTB | Glutathione S-transferase P 1 | 2.5.1.18 | 0.440 | |
2psj | CEI | Renilla-luciferin 2-monooxygenase | 1.13.12.5 | 0.440 | |
2uuk | 897 | Prothrombin | 3.4.21.5 | 0.440 | |
3l3m | A92 | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.440 | |
3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.440 | |
4epq | 0RR | Poly(ADP-ribose) glycohydrolase | / | 0.440 | |
4jq2 | SUZ | Aldo-keto reductase family 1 member C2 | / | 0.440 |