Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2pci | SAH | Diphthine synthase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2pci | SAH | Diphthine synthase | / | 1.000 | |
| 2dek | SAH | Diphthine synthase | / | 0.683 | |
| 2e8h | SAH | Diphthine synthase | / | 0.680 | |
| 2ek2 | SAH | Diphthine synthase | / | 0.676 | |
| 2dsg | SAH | Diphthine synthase | / | 0.675 | |
| 2egb | SAH | Diphthine synthase | / | 0.674 | |
| 2emu | SAH | Diphthine synthase | / | 0.674 | |
| 2emr | SAH | Diphthine synthase | / | 0.671 | |
| 2dxw | SAH | Diphthine synthase | / | 0.670 | |
| 2e08 | SAH | Diphthine synthase | / | 0.670 | |
| 2owu | SAH | Diphthine synthase | / | 0.668 | |
| 2e8q | SAH | Diphthine synthase | / | 0.666 | |
| 2eh5 | SAH | Diphthine synthase | / | 0.666 | |
| 2p5f | SAH | Diphthine synthase | / | 0.666 | |
| 2p6i | SAH | Diphthine synthase | / | 0.666 | |
| 2owk | SAH | Diphthine synthase | / | 0.665 | |
| 2ehl | SAH | Diphthine synthase | / | 0.664 | |
| 2dxv | SAH | Diphthine synthase | / | 0.663 | |
| 2e7r | SAH | Diphthine synthase | / | 0.663 | |
| 2dv4 | SAH | Diphthine synthase | / | 0.662 | |
| 2egl | SAH | Diphthine synthase | / | 0.662 | |
| 2p5c | SAH | Diphthine synthase | / | 0.662 | |
| 2p6l | SAH | Diphthine synthase | / | 0.662 | |
| 2ele | SAH | Diphthine synthase | / | 0.661 | |
| 2pb6 | SAH | Diphthine synthase | / | 0.661 | |
| 2dv7 | SAH | Diphthine synthase | / | 0.660 | |
| 2eh2 | SAH | Diphthine synthase | / | 0.660 | |
| 2ejk | SAH | Diphthine synthase | / | 0.660 | |
| 2dsh | SAH | Diphthine synthase | / | 0.659 | |
| 2eni | SAH | Diphthine synthase | / | 0.659 | |
| 2pcg | SAH | Diphthine synthase | / | 0.659 | |
| 2pcm | SAH | Diphthine synthase | / | 0.657 | |
| 1wng | SAH | Diphthine synthase | / | 0.656 | |
| 2dsi | SAH | Diphthine synthase | / | 0.656 | |
| 2el0 | SAH | Diphthine synthase | / | 0.656 | |
| 2p2x | SAH | Diphthine synthase | / | 0.656 | |
| 2p6d | SAH | Diphthine synthase | / | 0.656 | |
| 2pch | SAH | Diphthine synthase | / | 0.656 | |
| 2ek3 | SAH | Diphthine synthase | / | 0.655 | |
| 2ek7 | SAH | Diphthine synthase | / | 0.655 | |
| 2hux | SAH | Diphthine synthase | / | 0.655 | |
| 2dv3 | SAH | Diphthine synthase | / | 0.654 | |
| 1vce | SAH | Diphthine synthase | / | 0.653 | |
| 2e16 | SAH | Diphthine synthase | / | 0.653 | |
| 2huq | SAH | Diphthine synthase | / | 0.653 | |
| 2pck | SAH | Diphthine synthase | / | 0.653 | |
| 2en5 | SAH | Diphthine synthase | / | 0.652 | |
| 2dv5 | SAH | Diphthine synthase | / | 0.651 | |
| 2e07 | SAH | Diphthine synthase | / | 0.651 | |
| 2eh4 | SAH | Diphthine synthase | / | 0.651 | |
| 2p6k | SAH | Diphthine synthase | / | 0.650 | |
| 2dxx | SAH | Diphthine synthase | / | 0.649 | |
| 2ed5 | SAH | Diphthine synthase | / | 0.649 | |
| 2e17 | SAH | Diphthine synthase | / | 0.648 | |
| 2e4n | SAH | Diphthine synthase | / | 0.648 | |
| 2e8r | SAH | Diphthine synthase | / | 0.647 | |
| 2owg | SAH | Diphthine synthase | / | 0.647 | |
| 2e8s | SAH | Diphthine synthase | / | 0.645 | |
| 2pb5 | SAH | Diphthine synthase | / | 0.645 | |
| 2eeq | SAH | Diphthine synthase | / | 0.644 | |
| 2egs | SAH | Diphthine synthase | / | 0.644 | |
| 2el3 | SAH | Diphthine synthase | / | 0.644 | |
| 2e15 | SAH | Diphthine synthase | / | 0.643 | |
| 2eka | SAH | Diphthine synthase | / | 0.643 | |
| 2hut | SAH | Diphthine synthase | / | 0.642 | |
| 2pb4 | SAH | Diphthine synthase | / | 0.642 | |
| 2z6r | SAH | Diphthine synthase | / | 0.641 | |
| 2p9d | SAH | Diphthine synthase | / | 0.640 | |
| 2owv | SAH | Diphthine synthase | / | 0.639 | |
| 2ejj | SAH | Diphthine synthase | / | 0.635 | |
| 2eld | SAH | Diphthine synthase | / | 0.631 | |
| 2huv | SAH | Diphthine synthase | / | 0.631 | |
| 2pca | SAH | Diphthine synthase | / | 0.618 | |
| 2hr8 | SAH | Diphthine synthase | / | 0.617 | |
| 2ek4 | SAH | Diphthine synthase | / | 0.615 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.597 | |
| 2owf | SAH | Diphthine synthase | / | 0.577 | |
| 2ejz | SAH | Diphthine synthase | / | 0.566 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.520 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.506 | |
| 1e1q | ANP | ATP synthase subunit alpha, mitochondrial | / | 0.498 | |
| 1e1q | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.498 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.495 | |
| 3vqs | JT1 | Genome polyprotein | / | 0.494 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.493 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.493 | |
| 2rhg | IGP | Tryptophan synthase alpha chain | / | 0.492 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.485 | |
| 2xhd | 7T9 | Glutamate receptor 2 | / | 0.485 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.484 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.483 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.481 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.479 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.478 | |
| 2rcy | NAP | Pyrroline-5-carboxylate reductase | / | 0.478 | |
| 4wud | ANP | DNA gyrase subunit B | / | 0.478 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.477 | |
| 2y3s | TIR | TamL | / | 0.476 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.476 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.476 | |
| 2bn4 | FMN | NADPH--cytochrome P450 reductase | / | 0.475 | |
| 2qbu | SAH | Precorrin-2 methyltransferase | / | 0.475 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.474 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.472 | |
| 1bmf | ANP | ATP synthase subunit alpha, mitochondrial | / | 0.471 | |
| 1bmf | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.471 | |
| 1y4l | SVR | Basic phospholipase A2 homolog 2 | / | 0.471 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.471 | |
| 3sp6 | IL2 | Peroxisome proliferator-activated receptor alpha | / | 0.471 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.471 | |
| 1tj0 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.470 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.470 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.470 | |
| 1h8h | ATP | ATP synthase subunit alpha, mitochondrial | / | 0.469 | |
| 1h8h | ATP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.469 | |
| 4djh | JDC | Kappa-type opioid receptor | / | 0.469 | |
| 2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.468 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.468 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.468 | |
| 1ep1 | FMN | Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit | 1.3.1.14 | 0.467 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.467 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.467 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.467 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.467 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.467 | |
| 1kfb | IGP | Tryptophan synthase alpha chain | / | 0.466 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.466 | |
| 2q5g | 1FA | Peroxisome proliferator-activated receptor delta | / | 0.466 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.466 | |
| 3m2u | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.466 | |
| 4dx9 | SER_ALA_VAL_THR | Integrin beta-1 | / | 0.466 | |
| 4dx9 | SER_ALA_VAL_THR | Integrin beta-1-binding protein 1 | / | 0.466 | |
| 2qs3 | UBE | Glutamate receptor ionotropic, kainate 1 | / | 0.465 | |
| 3ijo | B4D | Glutamate receptor 2 | / | 0.465 | |
| 5eb5 | FAD | (R)-mandelonitrile lyase 1 | 4.1.2.10 | 0.465 | |
| 2wed | PP6 | Penicillopepsin-1 | 3.4.23.20 | 0.464 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.464 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.464 | |
| 3ig6 | 438 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.464 | |
| 4djy | 0KR | Beta-secretase 1 | 3.4.23.46 | 0.464 | |
| 4lcj | NAD | C-terminal-binding protein 2 | / | 0.464 | |
| 1beu | IPL | Tryptophan synthase alpha chain | / | 0.463 | |
| 1bim | 0QB | Renin | 3.4.23.15 | 0.463 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.463 | |
| 1e5q | NDP | Saccharopine dehydrogenase [NADP(+), L-glutamate-forming] | 1.5.1.10 | 0.463 | |
| 1f8f | NAD | Benzyl alcohol dehydrogenase | / | 0.463 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.463 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.463 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.463 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.463 | |
| 3bg7 | FAD | Pyranose 2-oxidase | / | 0.463 | |
| 3i5z | Z48 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.463 | |
| 3ieu | GDP | GTPase Era | / | 0.463 | |
| 3m30 | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.463 | |
| 3m30 | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.463 | |
| 3nut | SAH | Precorrin-3 methylase | / | 0.463 | |
| 1f8w | FAD | NADH peroxidase | 1.11.1.1 | 0.462 | |
| 1k7f | IAV | Tryptophan synthase alpha chain | / | 0.462 | |
| 1lbc | CYZ | Glutamate receptor 2 | / | 0.462 | |
| 1mp0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.462 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.462 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.462 | |
| 2y1t | DUD | SPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS | 3.6.1.23 | 0.462 | |
| 2z7h | GG3 | Geranylgeranyl pyrophosphate synthase | / | 0.462 | |
| 3up5 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.462 | |
| 3vn2 | TLS | Peroxisome proliferator-activated receptor gamma | / | 0.462 | |
| 4mqy | 2CW | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.462 | |
| 1dhr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.461 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.461 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.461 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.461 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.461 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.461 | |
| 5hws | NAP | 2-dehydropantoate 2-reductase | / | 0.461 | |
| 1x1d | SAH | C-20 methyltransferase | / | 0.460 | |
| 2clq | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.460 | |
| 3orf | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.460 | |
| 3zh8 | C58 | Protein kinase C iota type | 2.7.11.13 | 0.460 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.460 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.460 | |
| 4ft7 | H3K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.460 | |
| 4l7f | 1V5 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.460 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.459 | |
| 2ahr | NAP | Pyrroline-5-carboxylate reductase | / | 0.459 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.459 | |
| 3to6 | LYS_CMC | Histone acetyltransferase ESA1 | / | 0.459 | |
| 3vvp | BNU | Uncharacterized protein | / | 0.459 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.459 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.459 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.459 | |
| 1o97 | FAD | Electron transfer flavoprotein subunit alpha | / | 0.458 | |
| 3ndc | SAH | Precorrin-4 C(11)-methyltransferase | 2.1.1.133 | 0.458 | |
| 4eak | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.458 | |
| 1vp6 | CMP | Cyclic nucleotide-gated potassium channel mll3241 | / | 0.457 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.457 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 2bf4 | FMN | NADPH--cytochrome P450 reductase | / | 0.456 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.456 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.456 | |
| 2npi | ATP | mRNA cleavage and polyadenylation factor CLP1 | / | 0.456 | |
| 2pob | GW4 | Peroxisome proliferator-activated receptor gamma | / | 0.456 | |
| 2w06 | FRV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
| 2xx9 | 1NF | Glutamate receptor 2 | / | 0.456 | |
| 3lzs | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.456 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.456 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.456 | |
| 4bie | IE6 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.456 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.456 | |
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.456 | |
| 4ohv | ANP | Protein clpf-1 | / | 0.456 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.455 | |
| 1u8v | FAD | 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase | / | 0.455 | |
| 2z54 | AB1 | Gag-Pol polyprotein | 3.4.23.16 | 0.455 | |
| 4iql | FMN | Enoyl-(Acyl-carrier-protein) reductase II | / | 0.455 | |
| 4wuc | ANP | DNA gyrase subunit B | / | 0.455 | |
| 4z63 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.455 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.454 | |
| 1mjb | ACO | Histone acetyltransferase ESA1 | / | 0.454 | |
| 1orr | NAD | CDP-paratose 2-epimerase | / | 0.454 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.454 | |
| 2bb3 | SAH | Cobalamin biosynthesis precorrin-6Y methylase (CbiE) | / | 0.454 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.454 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.454 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.454 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.454 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.454 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.454 | |
| 4c0b | ATP | mRNA cleavage and polyadenylation factor CLP1 | / | 0.454 | |
| 4ge7 | 0K5 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.454 | |
| 4i8z | G08 | Gag-Pol polyprotein | 3.4.23.16 | 0.454 | |
| 4prv | ADP | DNA gyrase subunit B | / | 0.454 | |
| 4wri | OKA | Okadaic acid binding protein 2-alpha | / | 0.454 | |
| 5adh | APR | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.454 | |
| 2af3 | COA | Phosphate acetyltransferase | 2.3.1.8 | 0.453 | |
| 2b53 | D23 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 2bjf | DXC | Choloylglycine hydrolase | 3.5.1.24 | 0.453 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.453 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 2zvc | SAH | Precorrin-3 C17-methyltransferase | / | 0.453 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 3ruf | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.453 | |
| 3v0p | 4GW | Histo-blood group ABO system transferase | / | 0.453 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.453 | |
| 4dh6 | 0KN | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 4gyz | D5M | Tyrosyl-DNA phosphodiesterase 2 | 3.1.4 | 0.453 | |
| 4m49 | 22Y | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.453 | |
| 4z5w | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.453 | |
| 1j1z | ATP | Argininosuccinate synthase | / | 0.452 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.452 | |
| 1nlm | UD1 | UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase | / | 0.452 | |
| 2y3r | TIR | TamL | / | 0.452 | |
| 3oix | FMN | Dihydroorotate dehydrogenase | / | 0.452 | |
| 3suf | SUE | Polyprotein | / | 0.452 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.452 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.451 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.451 | |
| 1ep3 | FMN | Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit | 1.3.1.14 | 0.451 | |
| 1ma0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.451 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 1t9g | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.451 | |
| 1vik | BAY | Gag-Pol polyprotein | / | 0.451 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 3bnk | FMN | Flavoredoxin | / | 0.451 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.451 | |
| 3sf6 | FDA | Glutaryl-CoA dehydrogenase | / | 0.451 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.451 | |
| 1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.450 | |
| 2a5k | AZP | Replicase polyprotein 1ab | 3.4.22 | 0.450 | |
| 2ifa | FMN | Uncharacterized protein | / | 0.450 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.450 | |
| 2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.450 | |
| 3a3y | OBN | Sodium/potassium-transporting ATPase subunit alpha | / | 0.450 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.450 | |
| 3mvq | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.450 | |
| 4h3j | 10W | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 4xr9 | NAD | CalS8 | / | 0.450 | |
| 5d3q | GDP | Dynamin-1 | 3.6.5.5 | 0.450 | |
| 5dqr | FAD | 7-hydroxymethyl chlorophyll a reductase, chloroplastic | 1.17.7.2 | 0.450 | |
| 1xl5 | 190 | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.449 | |
| 2ck3 | ANP | ATP synthase subunit alpha, mitochondrial | / | 0.449 | |
| 2ck3 | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.449 | |
| 2v7q | ATP | ATP synthase subunit alpha, mitochondrial | / | 0.449 | |
| 2v7q | ATP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.449 | |
| 2w9s | TOP | Dihydrofolate reductase type 1 from Tn4003 | 1.5.1.3 | 0.449 | |
| 2yyi | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.449 | |
| 3ump | ATP | ATP-dependent 6-phosphofructokinase isozyme 2 | 2.7.1.11 | 0.449 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.449 | |
| 4fk8 | FAD | Ferredoxin--NADP reductase | / | 0.449 | |
| 4h80 | 04T | Aldehyde dehydrogenase, dimeric NADP-preferring | / | 0.449 | |
| 4i1i | NAD | Malate dehydrogenase | / | 0.449 | |
| 4xuh | SFI | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 2b4q | NAP | Rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.448 | |
| 2ome | NAD | C-terminal-binding protein 2 | / | 0.448 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 3em3 | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 3i6i | NDP | Putative leucoanthocyanidin reductase 1 | / | 0.448 | |
| 3tne | RIT | Candidapepsin-1 | 3.4.23.24 | 0.448 | |
| 4dpu | AGS | Mevalonate diphosphate decarboxylase | / | 0.448 | |
| 4dpy | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.448 | |
| 5c77 | SAH | Protein arginine N-methyltransferase SFM1 | / | 0.448 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.448 | |
| 1hyg | NAP | L-2-hydroxycarboxylate dehydrogenase (NAD(P)(+)) | / | 0.447 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.447 | |
| 3a3g | DLZ | Lumazine protein | / | 0.447 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 3l9l | L9L | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.447 | |
| 3oht | 1N1 | Mitogen-activated protein kinase | / | 0.447 | |
| 3u9e | COA | Lmo1369 protein | / | 0.447 | |
| 3ut5 | LOC | Tubulin beta chain | / | 0.447 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.447 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.447 | |
| 4dpf | 0LG | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 4kla | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.447 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.447 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.446 | |
| 1j9z | FAD | NADPH--cytochrome P450 reductase | / | 0.446 | |
| 1lf3 | EH5 | Plasmepsin-2 | 3.4.23.39 | 0.446 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.446 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.446 | |
| 3bc3 | OPT | Cathepsin L1 | 3.4.22.15 | 0.446 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.446 | |
| 3ea0 | ATP | ATPase, ParA family | / | 0.446 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.446 | |
| 3ixj | 586 | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 3pnd | FAD | FAD:protein FMN transferase | / | 0.446 | |
| 3u33 | FAD | Putative acyl-CoA dehydrogenase AidB | 1.3.99 | 0.446 | |
| 3uoy | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.446 | |
| 3v0o | 4GW | Histo-blood group ABO system transferase | / | 0.446 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.446 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.446 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.446 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 4mv8 | ACP | Biotin carboxylase | 6.3.4.14 | 0.446 | |
| 4r21 | STR | Cytochrome P450 family 17 polypeptide 2 | / | 0.446 | |
| 1gee | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.445 | |
| 1pdh | FAS | p-hydroxybenzoate hydroxylase | / | 0.445 | |
| 1tj2 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.445 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.445 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.445 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.445 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.445 | |
| 3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.445 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.445 | |
| 4q4k | FMN | Uncharacterized protein | / | 0.445 | |
| 1tv8 | SAM | GTP 3',8-cyclase | 4.1.99.18 | 0.444 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.444 | |
| 2ien | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 2jj2 | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.444 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.444 | |
| 2q4b | NAP | Uncharacterized protein At5g02240 | / | 0.444 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.444 | |
| 2w3b | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 3ad9 | NAD | Subunit alpha of sarocosine oxidase | / | 0.444 | |
| 3dxm | N24 | Actin-related protein 3 | / | 0.444 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3img | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.444 | |
| 3lb8 | FAD | Putidaredoxin reductase | 1.18.1.5 | 0.444 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.444 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.444 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.444 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.443 | |
| 1eio | GCH | Gastrotropin | / | 0.443 | |
| 1opm | IYG | Peptidyl-glycine alpha-amidating monooxygenase | 1.14.17.3 | 0.443 | |
| 1phg | MYT | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 1udy | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.443 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 2b7a | IZA | Tyrosine-protein kinase JAK2 | / | 0.443 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 3a1c | ACP | Probable copper-exporting P-type ATPase A | 3.6.3.54 | 0.443 | |
| 3c1y | 2BA | DNA integrity scanning protein DisA | / | 0.443 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.443 | |
| 3tfu | PL8 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.443 | |
| 4iv6 | FDA | Isovaleryl-CoA dehydrogenase | / | 0.443 | |
| 4l4x | NDP | AmphI | / | 0.443 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.443 | |
| 4yao | FMN | NADPH--cytochrome P450 reductase | / | 0.443 | |
| 5f8e | SAH | Possible transcriptional regulatory protein | / | 0.443 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 1nuu | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.442 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.442 | |
| 2fn7 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.442 | |
| 2h9i | EAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 2y3r | TRK | TamL | / | 0.442 | |
| 3a4v | NAD | NDP-sugar epimerase | / | 0.442 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.442 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.442 | |
| 4ips | 1G4 | Mycocyclosin synthase | 1.14.21.9 | 0.442 | |
| 4nd4 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.442 | |
| 1civ | NAP | Malate dehydrogenase [NADP], chloroplastic | 1.1.1.82 | 0.441 | |
| 1nyx | DRF | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.441 | |
| 1rfv | ADP | Pyridoxal kinase | 2.7.1.35 | 0.441 | |
| 1zth | ADP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.441 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.441 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.441 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.441 | |
| 2i4z | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 2npa | MMB | Peroxisome proliferator-activated receptor alpha | / | 0.441 | |
| 2psw | COA | N-alpha-acetyltransferase 50 | / | 0.441 | |
| 2ylz | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.441 | |
| 3v3m | 0EN | Replicase polyprotein 1a | 3.4.19.12 | 0.441 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.441 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.441 | |
| 4emt | C2E | Stimulator of interferon genes protein | / | 0.441 | |
| 4kug | NAD | 3-hydroxybutyryl-CoA dehydrogenase | / | 0.441 | |
| 4xj4 | 3AT | Cyclic GMP-AMP synthase | / | 0.441 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.441 | |
| 1a9z | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.440 | |
| 1dxo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 1ege | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.440 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.440 | |
| 1omo | NAD | Alanine dehydrogenase | / | 0.440 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.440 | |
| 2cft | PLP | Pyridoxal phosphate phosphatase | / | 0.440 | |
| 2dft | ADP | Shikimate kinase | 2.7.1.71 | 0.440 | |
| 2fon | FAD | Acyl-coenzyme A oxidase | / | 0.440 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 2vnk | FAD | NADPH:ferredoxin reductase | / | 0.440 | |
| 2x06 | NAD | L-sulfolactate dehydrogenase | / | 0.440 | |
| 3ahn | 3A1 | Oligopeptidase | / | 0.440 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.440 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.440 | |
| 3lpi | Z74 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.440 | |
| 3pmy | 41L | Endothiapepsin | 3.4.23.22 | 0.440 | |
| 3pwm | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 3rai | X85 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.440 | |
| 3s87 | ADP | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.440 | |
| 4mv1 | ADP | Biotin carboxylase | 6.3.4.14 | 0.440 |