Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2pch | SAH | Diphthine synthase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2pch | SAH | Diphthine synthase | / | 1.000 | |
| 2dv3 | SAH | Diphthine synthase | / | 0.830 | |
| 2e7r | SAH | Diphthine synthase | / | 0.824 | |
| 2pcg | SAH | Diphthine synthase | / | 0.813 | |
| 2hux | SAH | Diphthine synthase | / | 0.809 | |
| 2dxx | SAH | Diphthine synthase | / | 0.804 | |
| 2pca | SAH | Diphthine synthase | / | 0.798 | |
| 2eld | SAH | Diphthine synthase | / | 0.785 | |
| 2e8q | SAH | Diphthine synthase | / | 0.781 | |
| 2pb5 | SAH | Diphthine synthase | / | 0.777 | |
| 2en5 | SAH | Diphthine synthase | / | 0.776 | |
| 1wng | SAH | Diphthine synthase | / | 0.770 | |
| 2p5c | SAH | Diphthine synthase | / | 0.764 | |
| 2owg | SAH | Diphthine synthase | / | 0.762 | |
| 2el0 | SAH | Diphthine synthase | / | 0.760 | |
| 2p9d | SAH | Diphthine synthase | / | 0.759 | |
| 2el3 | SAH | Diphthine synthase | / | 0.758 | |
| 2eh4 | SAH | Diphthine synthase | / | 0.746 | |
| 2ek4 | SAH | Diphthine synthase | / | 0.746 | |
| 2pck | SAH | Diphthine synthase | / | 0.744 | |
| 2pb4 | SAH | Diphthine synthase | / | 0.742 | |
| 2dxw | SAH | Diphthine synthase | / | 0.734 | |
| 2ejk | SAH | Diphthine synthase | / | 0.734 | |
| 2pb6 | SAH | Diphthine synthase | / | 0.733 | |
| 2ek7 | SAH | Diphthine synthase | / | 0.729 | |
| 2dv7 | SAH | Diphthine synthase | / | 0.726 | |
| 2dxv | SAH | Diphthine synthase | / | 0.720 | |
| 2huv | SAH | Diphthine synthase | / | 0.712 | |
| 2e4n | SAH | Diphthine synthase | / | 0.707 | |
| 2p6i | SAH | Diphthine synthase | / | 0.707 | |
| 2ele | SAH | Diphthine synthase | / | 0.704 | |
| 2egb | SAH | Diphthine synthase | / | 0.700 | |
| 2egl | SAH | Diphthine synthase | / | 0.698 | |
| 2p5f | SAH | Diphthine synthase | / | 0.693 | |
| 2emr | SAH | Diphthine synthase | / | 0.691 | |
| 2dsg | SAH | Diphthine synthase | / | 0.687 | |
| 2ed5 | SAH | Diphthine synthase | / | 0.687 | |
| 2dv4 | SAH | Diphthine synthase | / | 0.686 | |
| 2e8s | SAH | Diphthine synthase | / | 0.686 | |
| 2e16 | SAH | Diphthine synthase | / | 0.685 | |
| 2pcm | SAH | Diphthine synthase | / | 0.684 | |
| 2dv5 | SAH | Diphthine synthase | / | 0.679 | |
| 2e8r | SAH | Diphthine synthase | / | 0.677 | |
| 2p2x | SAH | Diphthine synthase | / | 0.677 | |
| 2dsh | SAH | Diphthine synthase | / | 0.676 | |
| 2ejj | SAH | Diphthine synthase | / | 0.672 | |
| 2eka | SAH | Diphthine synthase | / | 0.671 | |
| 2egs | SAH | Diphthine synthase | / | 0.670 | |
| 2huq | SAH | Diphthine synthase | / | 0.668 | |
| 2p6d | SAH | Diphthine synthase | / | 0.668 | |
| 2p6k | SAH | Diphthine synthase | / | 0.667 | |
| 1vce | SAH | Diphthine synthase | / | 0.663 | |
| 2eh5 | SAH | Diphthine synthase | / | 0.663 | |
| 2emu | SAH | Diphthine synthase | / | 0.663 | |
| 2dsi | SAH | Diphthine synthase | / | 0.661 | |
| 2eni | SAH | Diphthine synthase | / | 0.660 | |
| 2ehl | SAH | Diphthine synthase | / | 0.657 | |
| 2owv | SAH | Diphthine synthase | / | 0.657 | |
| 2e07 | SAH | Diphthine synthase | / | 0.656 | |
| 2hr8 | SAH | Diphthine synthase | / | 0.654 | |
| 2p6l | SAH | Diphthine synthase | / | 0.644 | |
| 2e08 | SAH | Diphthine synthase | / | 0.643 | |
| 2ek3 | SAH | Diphthine synthase | / | 0.642 | |
| 2pci | SAH | Diphthine synthase | / | 0.636 | |
| 2z6r | SAH | Diphthine synthase | / | 0.630 | |
| 2dek | SAH | Diphthine synthase | / | 0.625 | |
| 2e8h | SAH | Diphthine synthase | / | 0.623 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.611 | |
| 2hut | SAH | Diphthine synthase | / | 0.608 | |
| 2ek2 | SAH | Diphthine synthase | / | 0.607 | |
| 2eh2 | SAH | Diphthine synthase | / | 0.606 | |
| 2owk | SAH | Diphthine synthase | / | 0.604 | |
| 2eeq | SAH | Diphthine synthase | / | 0.584 | |
| 2owf | SAH | Diphthine synthase | / | 0.578 | |
| 2owu | SAH | Diphthine synthase | / | 0.575 | |
| 2e15 | SAH | Diphthine synthase | / | 0.569 | |
| 2e17 | SAH | Diphthine synthase | / | 0.569 | |
| 2ejz | SAH | Diphthine synthase | / | 0.563 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.508 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.498 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.494 | |
| 1f8f | NAD | Benzyl alcohol dehydrogenase | / | 0.493 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.489 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.485 | |
| 2xhd | 7T9 | Glutamate receptor 2 | / | 0.483 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.482 | |
| 1dhr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.481 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.479 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.478 | |
| 4iql | FMN | Enoyl-(Acyl-carrier-protein) reductase II | / | 0.477 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.475 | |
| 1lbc | CYZ | Glutamate receptor 2 | / | 0.474 | |
| 3upk | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.474 | |
| 2ahr | NAP | Pyrroline-5-carboxylate reductase | / | 0.473 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.473 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.473 | |
| 3ijo | B4D | Glutamate receptor 2 | / | 0.473 | |
| 2z7h | GG3 | Geranylgeranyl pyrophosphate synthase | / | 0.472 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.472 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.472 | |
| 1pjc | NAD | Alanine dehydrogenase | / | 0.471 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.470 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.470 | |
| 2y3s | TIR | TamL | / | 0.470 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.470 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.469 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.469 | |
| 3up5 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.469 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.469 | |
| 4r21 | STR | Cytochrome P450 family 17 polypeptide 2 | / | 0.469 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.468 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.468 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.468 | |
| 2bf4 | FMN | NADPH--cytochrome P450 reductase | / | 0.468 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.468 | |
| 4wri | OKA | Okadaic acid binding protein 2-alpha | / | 0.468 | |
| 2clq | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.467 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.467 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.467 | |
| 3f3s | NAD | Lambda-crystallin homolog | / | 0.467 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.467 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.467 | |
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.467 | |
| 1x1d | SAH | C-20 methyltransferase | / | 0.466 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.466 | |
| 3vqs | JT1 | Genome polyprotein | / | 0.466 | |
| 4i1i | NAD | Malate dehydrogenase | / | 0.466 | |
| 1fy7 | COA | Histone acetyltransferase ESA1 | / | 0.465 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.465 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.465 | |
| 3u4o | 08E | Genome polyprotein | 2.7.7.48 | 0.465 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.464 | |
| 3bc3 | OPT | Cathepsin L1 | 3.4.22.15 | 0.464 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.464 | |
| 3ig6 | 438 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.464 | |
| 4dpu | AGS | Mevalonate diphosphate decarboxylase | / | 0.464 | |
| 4pl0 | ANP | Microcin-J25 export ATP-binding/permease protein McjD | / | 0.464 | |
| 5eb5 | FAD | (R)-mandelonitrile lyase 1 | 4.1.2.10 | 0.464 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.463 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.463 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.463 | |
| 3tfu | PL8 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.463 | |
| 3vn2 | TLS | Peroxisome proliferator-activated receptor gamma | / | 0.463 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.463 | |
| 1mj9 | COA | Histone acetyltransferase ESA1 | / | 0.462 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.462 | |
| 2i7p | ACO | Pantothenate kinase 3 | 2.7.1.33 | 0.462 | |
| 1bim | 0QB | Renin | 3.4.23.15 | 0.461 | |
| 1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.461 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.461 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.461 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.461 | |
| 4h3j | 10W | Beta-secretase 1 | 3.4.23.46 | 0.461 | |
| 2fgj | ATP | Alpha-hemolysin translocation ATP-binding protein HlyB | / | 0.460 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.460 | |
| 3uoz | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.460 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.460 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.460 | |
| 4wud | ANP | DNA gyrase subunit B | / | 0.460 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.459 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.459 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.459 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.459 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.459 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.459 | |
| 3a3g | DLZ | Lumazine protein | / | 0.459 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.459 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.459 | |
| 4z63 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.459 | |
| 3frq | ERY | Erythromycin resistance repressor protein | / | 0.458 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.458 | |
| 3uoy | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.458 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.458 | |
| 1o97 | FAD | Electron transfer flavoprotein subunit alpha | / | 0.457 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.457 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.457 | |
| 4wuc | ANP | DNA gyrase subunit B | / | 0.457 | |
| 1zio | AP5 | Adenylate kinase | / | 0.456 | |
| 2a87 | FAD | Thioredoxin reductase | 1.8.1.9 | 0.456 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.456 | |
| 2y3r | TRK | TamL | / | 0.456 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.456 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.456 | |
| 4djy | 0KR | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 4fv7 | E94 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.456 | |
| 4jlm | 1NN | Deoxycytidine kinase | 2.7.1.74 | 0.456 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.455 | |
| 2c27 | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.455 | |
| 2qd3 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.455 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.455 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.455 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.455 | |
| 4prx | ADP | DNA gyrase subunit B | / | 0.455 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.455 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 2bjf | DXC | Choloylglycine hydrolase | 3.5.1.24 | 0.454 | |
| 2bn4 | FMN | NADPH--cytochrome P450 reductase | / | 0.454 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.454 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.454 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.454 | |
| 4ips | 1G4 | Mycocyclosin synthase | 1.14.21.9 | 0.454 | |
| 4oqy | NDP | (S)-imine reductase | / | 0.454 | |
| 4xuh | SFI | Peroxisome proliferator-activated receptor gamma | / | 0.454 | |
| 1opm | IYG | Peptidyl-glycine alpha-amidating monooxygenase | 1.14.17.3 | 0.453 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.453 | |
| 2ifa | FMN | Uncharacterized protein | / | 0.453 | |
| 2rcy | NAP | Pyrroline-5-carboxylate reductase | / | 0.453 | |
| 3d8b | ADP | Fidgetin-like protein 1 | 3.6.4 | 0.453 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 3ruf | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.453 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.453 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.453 | |
| 5dp2 | NAP | CurF | / | 0.453 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.452 | |
| 2i4z | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.452 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.452 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.452 | |
| 4f32 | N32 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | / | 0.452 | |
| 4i1n | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.452 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.451 | |
| 1nuq | NXX | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.451 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.451 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.451 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.451 | |
| 2q5g | 1FA | Peroxisome proliferator-activated receptor delta | / | 0.451 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.451 | |
| 3dxm | N24 | Actin-related protein 3 | / | 0.451 | |
| 4qi7 | FAD | Cellobiose dehydrogenase | / | 0.451 | |
| 4yao | FMN | NADPH--cytochrome P450 reductase | / | 0.451 | |
| 1juv | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.450 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.450 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.450 | |
| 3ihg | VAK | Aklavinone 12-hydroxylase RdmE | / | 0.450 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.450 | |
| 3to6 | LYS_CMC | Histone acetyltransferase ESA1 | / | 0.450 | |
| 4frk | DWD | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.450 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.450 | |
| 5c8w | PCG | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.450 | |
| 1l2t | ATP | Uncharacterized ABC transporter ATP-binding protein MJ0796 | / | 0.449 | |
| 1u3d | FAD | Cryptochrome-1 | / | 0.449 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.449 | |
| 2fgk | ATP | Alpha-hemolysin translocation ATP-binding protein HlyB | / | 0.449 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.449 | |
| 3i5z | Z48 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.449 | |
| 3kc3 | MK2 | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.449 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.449 | |
| 3zh8 | C58 | Protein kinase C iota type | 2.7.11.13 | 0.449 | |
| 4b65 | FAD | L-ornithine N(5)-monooxygenase | / | 0.449 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.449 | |
| 4gl4 | NAI | Alcohol dehydrogenase class-3 | / | 0.449 | |
| 4hxy | NDP | Plm1 | / | 0.449 | |
| 4xr9 | NAD | CalS8 | / | 0.449 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.448 | |
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.448 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.448 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.448 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.448 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.448 | |
| 2pj4 | 414 | Carboxypeptidase B | / | 0.448 | |
| 2w3b | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 3bnk | FMN | Flavoredoxin | / | 0.448 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 3hyo | ADP | Pyridoxal kinase | / | 0.448 | |
| 3swq | EPU | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.448 | |
| 3tne | RIT | Candidapepsin-1 | 3.4.23.24 | 0.448 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.448 | |
| 4h3f | 10O | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 1jed | ADP | Sulfate adenylyltransferase | / | 0.447 | |
| 1rdt | 570 | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.447 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.447 | |
| 1y4l | SVR | Basic phospholipase A2 homolog 2 | / | 0.447 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.447 | |
| 3ndc | SAH | Precorrin-4 C(11)-methyltransferase | 2.1.1.133 | 0.447 | |
| 4eu9 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.447 | |
| 4m49 | 22Y | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.447 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.447 | |
| 5c1m | CLR | Mu-type opioid receptor | / | 0.447 | |
| 1jg0 | DDT | Thymidylate synthase | / | 0.446 | |
| 1nbo | NAD | Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic | 1.2.1.13 | 0.446 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.446 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.446 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.446 | |
| 2qbu | SAH | Precorrin-2 methyltransferase | / | 0.446 | |
| 3ik6 | HCZ | Glutamate receptor 2 | / | 0.446 | |
| 3sf6 | FDA | Glutaryl-CoA dehydrogenase | / | 0.446 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.446 | |
| 4ejn | 0R4 | RAC-alpha serine/threonine-protein kinase | 2.7.11.1 | 0.446 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.446 | |
| 4m6j | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.445 | |
| 1cdo | NAD | Alcohol dehydrogenase 1 | 1.1.1.1 | 0.445 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.445 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.445 | |
| 2cmj | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.445 | |
| 2gna | GDU | UDP-N-acetylglucosamine 4,6-dehydratase (inverting) | 4.2.1.115 | 0.445 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.445 | |
| 2q7v | FAD | Thioredoxin reductase | / | 0.445 | |
| 2vwq | NAP | Glucose 1-dehydrogenase | / | 0.445 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.445 | |
| 2xc3 | RT8 | Steroid C26-monooxygenase | 1.14.13.141 | 0.445 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.445 | |
| 2xx9 | 1NF | Glutamate receptor 2 | / | 0.445 | |
| 2znp | K55 | Peroxisome proliferator-activated receptor delta | / | 0.445 | |
| 3c14 | FOK | Adenylate cyclase type 2 | / | 0.445 | |
| 3c14 | FOK | Adenylate cyclase type 5 | / | 0.445 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3p2e | SAH | 16S rRNA (adenine(1408)-N(1))-methyltransferase | 2.1.1.180 | 0.445 | |
| 3uov | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.445 | |
| 4b1r | ITC | Tetracycline repressor protein class D | / | 0.445 | |
| 4dd8 | BAT | Disintegrin and metalloproteinase domain-containing protein 8 | 3.4.24 | 0.445 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 1nvs | UCM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.444 | |
| 1udy | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.444 | |
| 2b53 | D23 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 2ewm | NAD | (S)-1-Phenylethanol dehydrogenase | 1.1.1.311 | 0.444 | |
| 2yyi | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.444 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.444 | |
| 3orf | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.444 | |
| 3pfd | FDA | Acyl-CoA dehydrogenase FadE25 | / | 0.444 | |
| 3qgf | 46F | Genome polyprotein | 2.7.7.48 | 0.444 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.444 | |
| 4lcj | NAD | C-terminal-binding protein 2 | / | 0.444 | |
| 5af7 | FAD | Acyl-CoA dehydrogenase | / | 0.444 | |
| 1bil | 0IU | Renin | 3.4.23.15 | 0.443 | |
| 1cbf | SAH | Cobalt-precorrin-4 C(11)-methyltransferase | 2.1.1.271 | 0.443 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.443 | |
| 1civ | NAP | Malate dehydrogenase [NADP], chloroplastic | 1.1.1.82 | 0.443 | |
| 1e3s | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.443 | |
| 1ja1 | FMN | NADPH--cytochrome P450 reductase | / | 0.443 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.443 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.443 | |
| 2cgv | 3B3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 2fr0 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.443 | |
| 2rhg | IGP | Tryptophan synthase alpha chain | / | 0.443 | |
| 2zrx | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.443 | |
| 3bl7 | DD1 | m7GpppX diphosphatase | 3.6.1.59 | 0.443 | |
| 3csc | ACO | Citrate synthase, mitochondrial | 2.3.3.1 | 0.443 | |
| 3dh7 | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.443 | |
| 3djj | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.443 | |
| 3kb1 | ADP | Iron-sulfur cluster carrier protein | / | 0.443 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 3phj | DHK | Shikimate dehydrogenase (NADP(+)) | / | 0.443 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.443 | |
| 4emt | C2E | Stimulator of interferon genes protein | / | 0.443 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.443 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.443 | |
| 5ao1 | DG3 | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.443 | |
| 5fl3 | ADP | Pili retraction protein PilT | / | 0.443 | |
| 1f0x | FAD | D-lactate dehydrogenase | 1.1.1.28 | 0.442 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.442 | |
| 1ja0 | FMN | NADPH--cytochrome P450 reductase | / | 0.442 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 1ma0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.442 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.442 | |
| 2af3 | COA | Phosphate acetyltransferase | 2.3.1.8 | 0.442 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.442 | |
| 2iqg | F2I | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 2qs3 | UBE | Glutamate receptor ionotropic, kainate 1 | / | 0.442 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.442 | |
| 4h1e | 10J | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4i8z | G08 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 5hws | NAP | 2-dehydropantoate 2-reductase | / | 0.442 | |
| 1e1q | ANP | ATP synthase subunit alpha, mitochondrial | / | 0.441 | |
| 1e1q | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.441 | |
| 1eio | GCH | Gastrotropin | / | 0.441 | |
| 1k7f | IAV | Tryptophan synthase alpha chain | / | 0.441 | |
| 1r6t | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.441 | |
| 2b7a | IZA | Tyrosine-protein kinase JAK2 | / | 0.441 | |
| 2b8l | 5HA | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 2hyd | ADP | Putative multidrug export ATP-binding/permease protein SAV1866 | 3.6.3 | 0.441 | |
| 2zjm | F1M | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 3a0t | ADP | Sensor histidine kinase | / | 0.441 | |
| 3a3y | OBN | Sodium/potassium-transporting ATPase subunit alpha | / | 0.441 | |
| 3ggo | NAI | Prephenate dehydrogenase | / | 0.441 | |
| 3ieu | GDP | GTPase Era | / | 0.441 | |
| 3m30 | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.441 | |
| 3m30 | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.441 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.441 | |
| 3r9u | FAD | Thioredoxin reductase | / | 0.441 | |
| 3syi | FAD | Sulfide-quinone reductase | / | 0.441 | |
| 3v2u | ATP | Protein GAL3 | / | 0.441 | |
| 3vvp | BNU | Uncharacterized protein | / | 0.441 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.441 | |
| 4xgx | ADP | FAD:protein FMN transferase | / | 0.441 | |
| 5dqr | FAD | 7-hydroxymethyl chlorophyll a reductase, chloroplastic | 1.17.7.2 | 0.441 | |
| 1f8w | FAD | NADH peroxidase | 1.11.1.1 | 0.440 | |
| 1nhh | ANP | DNA mismatch repair protein MutL | / | 0.440 | |
| 1owm | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.440 | |
| 1phg | MYT | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 1tv8 | SAM | GTP 3',8-cyclase | 4.1.99.18 | 0.440 | |
| 1u3c | FAD | Cryptochrome-1 | / | 0.440 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.440 | |
| 2bb3 | SAH | Cobalamin biosynthesis precorrin-6Y methylase (CbiE) | / | 0.440 | |
| 2ekl | NAD | D-3-phosphoglycerate dehydrogenase | / | 0.440 | |
| 3gvh | NAD | Malate dehydrogenase | / | 0.440 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.440 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.440 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.440 | |
| 3uyl | TYD | Probable NDP-rhamnosyltransferase | / | 0.440 | |
| 3v0o | 4GW | Histo-blood group ABO system transferase | / | 0.440 | |
| 3vsw | R31 | Renin | 3.4.23.15 | 0.440 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 4dfg | 0JV | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 4dxd | 9PC | Cell division protein FtsZ | / | 0.440 | |
| 4mlp | 2CX | Cryptochrome-2 | / | 0.440 | |
| 4rpg | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.440 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 5eai | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 |