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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2pb6SAHDiphthine synthase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
2pb6SAHDiphthine synthase/1.000
2e4nSAHDiphthine synthase/0.853
2ek4SAHDiphthine synthase/0.833
2emuSAHDiphthine synthase/0.830
2eldSAHDiphthine synthase/0.824
2huxSAHDiphthine synthase/0.811
2e8qSAHDiphthine synthase/0.806
2dsgSAHDiphthine synthase/0.804
2el3SAHDiphthine synthase/0.800
2pb4SAHDiphthine synthase/0.800
2en5SAHDiphthine synthase/0.784
2ek2SAHDiphthine synthase/0.778
2ek7SAHDiphthine synthase/0.770
2emrSAHDiphthine synthase/0.762
2e16SAHDiphthine synthase/0.760
2e8sSAHDiphthine synthase/0.752
2dv3SAHDiphthine synthase/0.751
2z6rSAHDiphthine synthase/0.749
2huvSAHDiphthine synthase/0.748
2ehlSAHDiphthine synthase/0.745
2pchSAHDiphthine synthase/0.742
2p6lSAHDiphthine synthase/0.741
2e8rSAHDiphthine synthase/0.739
2e17SAHDiphthine synthase/0.736
2owkSAHDiphthine synthase/0.731
2pcmSAHDiphthine synthase/0.731
2dxvSAHDiphthine synthase/0.729
2eh5SAHDiphthine synthase/0.726
2dxwSAHDiphthine synthase/0.724
2eh2SAHDiphthine synthase/0.724
2dekSAHDiphthine synthase/0.721
2eniSAHDiphthine synthase/0.721
2dv4SAHDiphthine synthase/0.718
2pcgSAHDiphthine synthase/0.706
2p6dSAHDiphthine synthase/0.705
1wngSAHDiphthine synthase/0.704
2ed5SAHDiphthine synthase/0.695
2el0SAHDiphthine synthase/0.691
2dv7SAHDiphthine synthase/0.690
2e07SAHDiphthine synthase/0.690
2hutSAHDiphthine synthase/0.684
1vceSAHDiphthine synthase/0.681
2eleSAHDiphthine synthase/0.670
2e7rSAHDiphthine synthase/0.669
2eh4SAHDiphthine synthase/0.666
2ejkSAHDiphthine synthase/0.666
2ekaSAHDiphthine synthase/0.665
2owgSAHDiphthine synthase/0.664
2e8hSAHDiphthine synthase/0.661
2pcaSAHDiphthine synthase/0.661
2eglSAHDiphthine synthase/0.660
2huqSAHDiphthine synthase/0.658
2pciSAHDiphthine synthase/0.658
2p6kSAHDiphthine synthase/0.651
2e15SAHDiphthine synthase/0.649
2ek3SAHDiphthine synthase/0.649
2pckSAHDiphthine synthase/0.649
2hr8SAHDiphthine synthase/0.641
2p9dSAHDiphthine synthase/0.636
2eeqSAHDiphthine synthase/0.632
2owuSAHDiphthine synthase/0.630
2dxxSAHDiphthine synthase/0.629
2pb5SAHDiphthine synthase/0.626
2owvSAHDiphthine synthase/0.623
2p5fSAHDiphthine synthase/0.610
2ejjSAHDiphthine synthase/0.608
2ed3SAHDiphthine synthase/0.605
2ejzSAHDiphthine synthase/0.604
2dsiSAHDiphthine synthase/0.602
2dshSAHDiphthine synthase/0.595
2e08SAHDiphthine synthase/0.589
2p5cSAHDiphthine synthase/0.589
2p2xSAHDiphthine synthase/0.588
2p6iSAHDiphthine synthase/0.580
2egsSAHDiphthine synthase/0.571
2owfSAHDiphthine synthase/0.570
2dv5SAHDiphthine synthase/0.569
2egbSAHDiphthine synthase/0.565
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.530
1xe55FEPlasmepsin-23.4.23.390.522
4jnkZHKL-lactate dehydrogenase A chain1.1.1.270.513
3gw9VNILanosterol 14-alpha-demethylase/0.508
4g2l0WLHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.504
4g7gVFVLanosterol 14-alpha-demethylase/0.494
1w6hTITPlasmepsin-23.4.23.390.493
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.491
4iqlFMNEnoyl-(Acyl-carrier-protein) reductase II/0.491
4q71FADBifunctional protein PutA/0.491
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.490
3up5FAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.490
4bfzZVZPantothenate kinase2.7.1.330.490
2bf4FMNNADPH--cytochrome P450 reductase/0.489
2hunNAD336aa long hypothetical dTDP-glucose 4,6-dehydratase/0.489
2pswCOAN-alpha-acetyltransferase 50/0.489
3tfuPL8Adenosylmethionine-8-amino-7-oxononanoate aminotransferase2.6.1.620.489
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.487
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.487
1ps9MDE2,4-dienoyl-CoA reductase1.3.1.340.486
2yy2IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.486
2ztmNADD(-)-3-hydroxybutyrate dehydrogenase/0.486
3djjFADGlutathione reductase, mitochondrial1.8.1.70.485
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.485
4bfxZVXPantothenate kinase2.7.1.330.485
1me6IVSPlasmepsin-23.4.23.390.484
3hl0NADMaleylacetate reductase/0.482
1lbcCYZGlutamate receptor 2/0.481
3d91REMRenin3.4.23.150.481
3uozFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.481
2il2LIXRenin3.4.23.150.479
4egbNADdTDP-glucose 4,6-dehydratase/0.479
1hdrNADDihydropteridine reductase1.5.1.340.478
3dh7FMNIsopentenyl-diphosphate delta-isomerase/0.478
1f8fNADBenzyl alcohol dehydrogenase/0.477
1h8hATPATP synthase subunit alpha, mitochondrial/0.477
1h8hATPATP synthase subunit beta, mitochondrial3.6.3.140.477
1xe65FPPlasmepsin-23.4.23.390.477
2ifaFMNUncharacterized protein/0.477
2qbuSAHPrecorrin-2 methyltransferase/0.477
4b4vL34Bifunctional protein FolD/0.477
1dhrNADDihydropteridine reductase1.5.1.340.476
1juvNDPDihydrofolate reductase1.5.1.30.476
2xhd7T9Glutamate receptor 2/0.476
3em0CHDFatty acid-binding protein 6, ileal (gastrotropin)/0.476
4dzzADPPlasmid partitioning protein ParF/0.476
4wudANPDNA gyrase subunit B/0.476
3dyqIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.475
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.475
3wv9FEGHmd co-occurring protein HcgE/0.475
1gg5FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.474
1x1aSAMC-20 methyltransferase/0.474
2gjlFMNNitronate monooxygenase1.13.12.160.474
2jb4A14Isopenicillin N synthase1.21.3.10.474
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.474
3iqhTYR_ASP_ILECysteine synthase2.5.1.470.474
3zoiM2WIsopenicillin N synthase1.21.3.10.474
4a83DXCMajor pollen allergen Bet v 1-A/0.474
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.473
2q5g1FAPeroxisome proliferator-activated receptor delta/0.473
2x7hPFNProstaglandin reductase 310.473
3ig6438Urokinase-type plasminogen activator3.4.21.730.473
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.473
2cmjNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.472
2qs3UBEGlutamate receptor ionotropic, kainate 1/0.472
2rlcCHDCholoylglycine hydrolase3.5.1.240.472
2y3sTIRTamL/0.472
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.472
4prvADPDNA gyrase subunit B/0.472
2c20NADUDP-glucose 4-epimerase/0.471
1g1aNADdTDP-glucose 4,6-dehydratase/0.470
1g63FMNEpidermin decarboxylase4.1.10.470
1xddAAYIntegrin alpha-L/0.470
2ojtUBAGlutamate receptor ionotropic, kainate 1/0.470
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.470
2q4bNAPUncharacterized protein At5g02240/0.470
3k3ePDBHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.470
1hb3SCVIsopenicillin N synthase1.21.3.10.469
1ma0NADAlcohol dehydrogenase class-31.1.1.10.469
1z7yAA5Cysteine synthase 12.5.1.470.469
2ozuACOHistone acetyltransferase KAT6A/0.469
2rbeNDPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.469
2x06NADL-sulfolactate dehydrogenase/0.469
2wyvNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.468
3bv7NAP3-oxo-5-beta-steroid 4-dehydrogenase/0.468
3slkNDPPolyketide synthase extender module 2/0.468
4a8v2ANMajor pollen allergen Bet v 1-J/0.468
4dbzNDPPutative ketoacyl reductase1.3.10.468
4i8zG08Gag-Pol polyprotein3.4.23.160.468
4q0kGA3Phytohormone-binding protein/0.468
4xuhSFIPeroxisome proliferator-activated receptor gamma/0.468
1hb1OCVIsopenicillin N synthase1.21.3.10.467
1xl5190Gag-Pol polyprotein3.4.23.160.467
2ztvNADD(-)-3-hydroxybutyrate dehydrogenase/0.467
3oev3OEProteasome subunit beta type-53.4.25.10.467
3oev3OEProteasome subunit beta type-63.4.25.10.467
4ejmNAPPutative zinc-binding dehydrogenase/0.467
1bim0QBRenin3.4.23.150.466
1cdoNADAlcohol dehydrogenase 11.1.1.10.466
1dirNADDihydropteridine reductase1.5.1.340.466
1kbo340NAD(P)H dehydrogenase [quinone] 11.6.5.20.466
1msmJE2Gag-Pol polyprotein3.4.23.160.466
2g8yNADHydroxycarboxylate dehydrogenase B/0.466
2gv8NDPThiol-specific monooxygenase1.14.130.466
3a3gDLZLumazine protein/0.466
3e8xNAPBH1520 protein/0.466
3ijoB4DGlutamate receptor 2/0.466
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.466
1mjaCOAHistone acetyltransferase ESA1/0.465
2ahrNAPPyrroline-5-carboxylate reductase/0.465
2b4rAESGlyceraldehyde-3-phosphate dehydrogenase/0.465
2he5NDPAldo-keto reductase family 1 member C211.1.10.465
2iyfERYOleandomycin glycosyltransferase2.4.10.465
2vwqNAPGlucose 1-dehydrogenase/0.465
2y60M8FIsopenicillin N synthase1.21.3.10.465
3flkNAITartrate dehydrogenase/decarboxylase1.1.1.930.465
3jsxCC2NAD(P)H dehydrogenase [quinone] 11.6.5.20.465
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.465
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.465
4gsuDWZL,D-transpeptidase 22.3.20.465
4irnFADAnaB/0.465
4pl0ANPMicrocin-J25 export ATP-binding/permease protein McjD/0.465
5dp2NAPCurF/0.465
1qiqACCIsopenicillin N synthase1.21.3.10.464
1siqFADGlutaryl-CoA dehydrogenase, mitochondrial1.3.8.60.464
1tehNADAlcohol dehydrogenase class-31.1.1.10.464
2fw3BUICarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.464
3d8bADPFidgetin-like protein 13.6.40.464
3in6FMNUncharacterized protein/0.464
3orfNADDihydropteridine reductase1.5.1.340.464
3te5NAI5'-AMP-activated protein kinase subunit gamma/0.464
3uoyFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.464
4hbgNDP3-oxoacyl-[acyl-carrier-protein] reductase1.1.1.1000.464
4wriOKAOkadaic acid binding protein 2-alpha/0.464
4z3dNDPCarbonyl reductase [NADPH] 11.1.1.1840.464
1t2cNAIL-lactate dehydrogenase1.1.1.270.463
1udaUFGUDP-glucose 4-epimerase5.1.3.20.463
2a94AP0L-lactate dehydrogenase1.1.1.270.463
2bjfDXCCholoylglycine hydrolase3.5.1.240.463
2rhgIGPTryptophan synthase alpha chain/0.463
3vn2TLSPeroxisome proliferator-activated receptor gamma/0.463
4dxd9PCCell division protein FtsZ/0.463
4eb7PLPCysteine desulfurase IscS 2/0.463
4j0v1H7Beta-secretase 13.4.23.460.463
2a87FADThioredoxin reductase1.8.1.90.462
2iviACWIsopenicillin N synthase1.21.3.10.462
3clxX22E3 ubiquitin-protein ligase XIAP6.3.20.462
4enhFVXCholesterol 24-hydroxylase/0.462
4kb9G79Protease/0.462
4nbwNADShort-chain dehydrogenase/reductase SDR/0.462
5eb5FAD(R)-mandelonitrile lyase 14.1.2.100.462
1mj9COAHistone acetyltransferase ESA1/0.461
1pjcNADAlanine dehydrogenase/0.461
1vikBAYGag-Pol polyprotein/0.461
2g1s4IGRenin3.4.23.150.461
4bc7FADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.461
4xr9NADCalS8/0.461
1e1qANPATP synthase subunit alpha, mitochondrial/0.460
1e1qANPATP synthase subunit beta, mitochondrial3.6.3.140.460
2c27ACOMycothiol acetyltransferase2.3.1.1890.460
2cftPLPPyridoxal phosphate phosphatase/0.460
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.460
2ien017Gag-Pol polyprotein3.4.23.160.460
2irzI02Beta-secretase 13.4.23.460.460
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.460
3i59N6RCRP-like cAMP-activated global transcriptional regulator/0.460
4ipw1G7Mycocyclosin synthase1.14.21.90.460
4m10ICDProstaglandin G/H synthase 21.14.99.10.460
4trnNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.460
2f81017Gag-Pol polyprotein3.4.23.160.459
2fxv5GPXanthine phosphoribosyltransferase2.4.2.220.459
2givACOHistone acetyltransferase KAT8/0.459
2y65ADPKinesin heavy chain/0.459
3a0tADPSensor histidine kinase/0.459
3lqfNADGalactitol dehydrogenase/0.459
3pwm017Gag-Pol polyprotein3.4.23.160.459
4opgFDAConserved Archaeal protein/0.459
4oxyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.459
1c7oPPGHemolysin/0.458
1e5qNDPSaccharopine dehydrogenase [NADP(+), L-glutamate-forming]1.5.1.100.458
1nupNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.458
1q5mNDPProstaglandin-E(2) 9-reductase1.1.1.1890.458
1x7hNDPPutative ketoacyl reductase1.3.10.458
2bn4FMNNADPH--cytochrome P450 reductase/0.458
2viyVG3Beta-secretase 13.4.23.460.458
3lzs017Gag-Pol polyprotein3.4.23.160.458
3phiNDPShikimate dehydrogenase (NADP(+))/0.458
3uovFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.458
3vt7VDXVitamin D3 receptor/0.458
4eakATP5'-AMP-activated protein kinase subunit gamma-1/0.458
4yaoFMNNADPH--cytochrome P450 reductase/0.458
5a0yCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.458
5a0yCOMMethyl-coenzyme M reductase I subunit beta2.8.4.10.458
5eaiFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.458
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.457
1fy7COAHistone acetyltransferase ESA1/0.457
1mp0NADAlcohol dehydrogenase class-31.1.1.10.457
1q0zAKAAclacinomycin methylesterase RdmC3.1.1.950.457
1qorNDPQuinone oxidoreductase 1/0.457
2npfMOUElongation factor 2/0.457
2rcyNAPPyrroline-5-carboxylate reductase/0.457
2znq401Peroxisome proliferator-activated receptor delta/0.457
3nsh957Beta-secretase 13.4.23.460.457
3p62FMNPentaerythritol tetranitrate reductase/0.457
3vdqNAD3-hydroxybutyrate dehydrogenase/0.457
3widNAPGlucose 1-dehydrogenase/0.457
4i0i957Beta-secretase 13.4.23.460.457
4jlj1NMDeoxycytidine kinase2.7.1.740.457
4oztP1AEcdysone receptor, putative/0.457
5jscFADPutative acyl-CoA dehydrogenase/0.457
1beuIPLTryptophan synthase alpha chain/0.456
1xl8152Peroxisomal carnitine O-octanoyltransferase2.3.1.1370.456
2hydADPPutative multidrug export ATP-binding/permease protein SAV18663.6.30.456
2w3bNDPDihydrofolate reductase1.5.1.30.456
3itjFADThioredoxin reductase 11.8.1.90.456
3sdkP3NProteasome subunit beta type-53.4.25.10.456
3sdkP3NProteasome subunit beta type-63.4.25.10.456
3vqsJT1Genome polyprotein/0.456
4gl4NAIAlcohol dehydrogenase class-3/0.456
2p83MR0Beta-secretase 13.4.23.460.455
2xfiXFIBeta-secretase 13.4.23.460.455
2z54AB1Gag-Pol polyprotein3.4.23.160.455
3lpjZ75Beta-secretase 13.4.23.460.455
3w8eNAD3-hydroxybutyrate dehydrogenase/0.455
4a81DXCMajor pollen allergen Bet v 1-A/0.455
4g3jVNTLanosterol 14-alpha-demethylase/0.455
4nd3NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.455
4z5wILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.455
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.455
4djhJDCKappa-type opioid receptor/0.455
1fm4DXCMajor pollen allergen Bet v 1-L/0.454
1lf2R37Plasmepsin-23.4.23.390.454
1orrNADCDP-paratose 2-epimerase/0.454
1tqf32PBeta-secretase 13.4.23.460.454
1v9aSAHUncharacterized protein/0.454
1xs7MMIBeta-secretase 13.4.23.460.454
1yqzCOACoenzyme A disulfide reductase/0.454
2q1wNADPutative nucleotide sugar epimerase/ dehydratase/0.454
3eheNADUDP-glucose 4-epimerase (GalE-1)/0.454
3lpkZ76Beta-secretase 13.4.23.460.454
3own3OWRenin3.4.23.150.454
3qe2FMNNADPH--cytochrome P450 reductase/0.454
3qfrFMNNADPH--cytochrome P450 reductase/0.454
4nbtNAD3-oxoacyl-[acyl-carrier-protein] reductase/0.454
1dxoFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.453
1g6kNADGlucose 1-dehydrogenase1.1.1.470.453
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.453
2fgjATPAlpha-hemolysin translocation ATP-binding protein HlyB/0.453
2vkeTACTetracycline repressor protein class D/0.453
2wecPP5Penicillopepsin-13.4.23.200.453
3bk2U5PRibonuclease J/0.453
3r7kFDAProbable acyl CoA dehydrogenase/0.453
3u9eCOALmo1369 protein/0.453
3uylTYDProbable NDP-rhamnosyltransferase/0.453
3vvpBNUUncharacterized protein/0.453
4bbyFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.453
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.453
4i1iNADMalate dehydrogenase/0.453
5adhAPRAlcohol dehydrogenase E chain1.1.1.10.453
1dr3TAPDihydrofolate reductase1.5.1.30.452
1gzuNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.452
1tj0FADBifunctional protein PutA1.5.5.20.452
1xkvATPPhosphoenolpyruvate carboxykinase (ATP)/0.452
2a92NAIL-lactate dehydrogenase/0.452
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.452
2fzwNADAlcohol dehydrogenase class-31.1.1.10.452
2p3b3TLV-1 PROTEASE protein/0.452
2p3b3TLV-1 protease/0.452
2pj4414Carboxypeptidase B/0.452
2x0iNAIMalate dehydrogenase/0.452
2xx91NFGlutamate receptor 2/0.452
2y1tDUDSPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS3.6.1.230.452
2y4gTIRTamL/0.452
3qwbNDPProbable quinone oxidoreductase1.6.5.50.452
3sf6FDAGlutaryl-CoA dehydrogenase/0.452
4bb3KKAIsopenicillin N synthase1.21.3.10.452
4mlp2CXCryptochrome-2/0.452
4r21STRCytochrome P450 family 17 polypeptide 2/0.452
1iy8NADLevodione reductase/0.451
1rx0FADIsobutyryl-CoA dehydrogenase, mitochondrial1.3.990.451
1x1bSAHC-20 methyltransferase/0.451
2bu9HFVIsopenicillin N synthase1.21.3.10.451
2dvlFADAcyl-CoA dehydrogenase/0.451
2g1r3IGRenin3.4.23.150.451
2w06FRVCyclin-dependent kinase 22.7.11.220.451
2znnS44Peroxisome proliferator-activated receptor alpha/0.451
3a3yOBNSodium/potassium-transporting ATPase subunit alpha/0.451
3iltTRUGlutamate receptor 2/0.451
3jzdNADMaleylacetate reductase/0.451
3lpiZ74Beta-secretase 13.4.23.460.451
3oibFDAPutative acyl-CoA dehydrogenase/0.451
3pqbVGPPutative oxidoreductase/0.451
3tneRITCandidapepsin-13.4.23.240.451
3zh8C58Protein kinase C iota type2.7.11.130.451
4cvmANPUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase/0.451
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.451
4i6aHMG3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.880.451
4jjiNADAlcohol dehydrogenase class-3/0.451
4ktoFADPutative isovaleryl-CoA dehydrogenase protein/0.451
1bxoPP7Penicillopepsin-13.4.23.200.450
1lf3EH5Plasmepsin-23.4.23.390.450
1omoNADAlanine dehydrogenase/0.450
1xvaSAMGlycine N-methyltransferase2.1.1.200.450
1y4lSVRBasic phospholipase A2 homolog 2/0.450
1zdwFLVPrenyltransferase/0.450
2b53D23Cyclin-dependent kinase 22.7.11.220.450
2dgnDOIAdenylosuccinate synthetase isozyme 1/0.450
2ewmNAD(S)-1-Phenylethanol dehydrogenase1.1.1.3110.450
2g226IGRenin3.4.23.150.450
2ylzFADPhenylacetone monooxygenase1.14.13.920.450
3iahNAPPutative oxoacyl-(Acyl carrier protein) reductase/0.450
3ivgFG5Pantothenate synthetase6.3.2.10.450
3m6iNADL-arabinitol 4-dehydrogenase1.1.1.120.450
3u33FADPutative acyl-CoA dehydrogenase AidB1.3.990.450
3wagTYDGlycosyltransferase/0.450
4fv7E94Mitogen-activated protein kinase 12.7.11.240.450
4h3f10OBeta-secretase 13.4.23.460.450
1egeFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.449
1x1dSAHC-20 methyltransferase/0.449
2hk9NAPShikimate dehydrogenase (NADP(+))/0.449
2v7qATPATP synthase subunit alpha, mitochondrial/0.449
2v7qATPATP synthase subunit beta, mitochondrial3.6.3.140.449
3cic316Beta-secretase 13.4.23.460.449
3f3sNADLambda-crystallin homolog/0.449
3nutSAHPrecorrin-3 methylase/0.449
3phjDHKShikimate dehydrogenase (NADP(+))/0.449
3raiX85Cyclin-dependent kinase 22.7.11.220.449
3up4FAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.449
3vt8YI3Vitamin D3 receptor/0.449
3zkyWT4Isopenicillin N synthase1.21.3.10.449
4bcaFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.449
4eywL0RCarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.449
4lutDCSAlanine racemase/0.449
5b1yNDP3-oxoacyl-[acyl-carrier-protein] reductase/0.449
1bwsNDPGDP-L-fucose synthase/0.448
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.448
1nzfUPGDNA beta-glucosyltransferase/0.448
1y7lASN_LEU_ASN_ILECysteine synthase2.5.1.470.448
1zioAP5Adenylate kinase/0.448
2b4tAESGlyceraldehyde-3-phosphate dehydrogenase/0.448
2ym1NAPPhenylacetone monooxygenase1.14.13.920.448
2zvcSAHPrecorrin-3 C17-methyltransferase/0.448
3d4pNADL-lactate dehydrogenase 11.1.1.270.448
3jziJZLBiotin carboxylase6.3.4.140.448
3lqsPSZD-alanine aminotransferase2.6.1.210.448
3qbhQBHBeta-secretase 13.4.23.460.448
4b65FADL-ornithine N(5)-monooxygenase/0.448
4dptAGSMevalonate diphosphate decarboxylase/0.448
4ji91M3Tyrosine-protein kinase JAK2/0.448
1bk0ACVIsopenicillin N synthase1.21.3.10.447
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.447
1eveE20Acetylcholinesterase3.1.1.70.447
1hygNAPL-2-hydroxycarboxylate dehydrogenase (NAD(P)(+))/0.447
1ja0FMNNADPH--cytochrome P450 reductase/0.447
1jueFMNDihydroorotate dehydrogenase A (fumarate)1.3.98.10.447
1kp3ATPArgininosuccinate synthase6.3.4.50.447
1t9gFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.447
2g247IGRenin3.4.23.150.447
2hrcCHDFerrochelatase, mitochondrial4.99.1.10.447
2npiATPmRNA cleavage and polyadenylation factor CLP1/0.447
3ik6HCZGlutamate receptor 2/0.447
3l9lL9LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.447
3owaFADAcyl-CoA dehydrogenase/0.447
3qgf46FGenome polyprotein2.7.7.480.447
4dpy2P0Mevalonate diphosphate decarboxylase/0.447
4dx9SER_ALA_VAL_THRIntegrin beta-1/0.447
4dx9SER_ALA_VAL_THRIntegrin beta-1-binding protein 1/0.447
4jtqNAPAldo-keto reductase family 1 member C2/0.447
4l7f1V5Mitogen-activated protein kinase 82.7.11.240.447
5af7FADAcyl-CoA dehydrogenase/0.447
5hwsNAP2-dehydropantoate 2-reductase/0.447
5irnADPNucleotide binding oligomerization domain containing 2/0.447
1bil0IURenin3.4.23.150.446
1i7gAZ2Peroxisome proliferator-activated receptor alpha/0.446
2gz8F3FOrf1a polyprotein/0.446
2is0I03Beta-secretase 13.4.23.460.446
3b70NAPEnoyl reductase LovC10.446
3ixj586Beta-secretase 13.4.23.460.446
3zdfNADGlyceraldehyde-3-phosphate dehydrogenase/0.446
4ef8FMNDihydroorotate dehydrogenase (fumarate)/0.446
4f4dCHDFerrochelatase, mitochondrial4.99.1.10.446
4jl5ADPAdenylate kinase/0.446
4uwmFMN3,6-diketocamphane 1,6 monooxygenase1.14.130.446
4xguADPPutative pachytene checkpoint protein 2/0.446
5c1mCLRMu-type opioid receptor/0.446
5dozNDPJamJ/0.446
1cf3FADGlucose oxidase1.1.3.40.445
1drhNAPDihydrofolate reductase1.5.1.30.445
1jedADPSulfate adenylyltransferase/0.445
1m0b0ZQGag-Pol polyprotein3.4.23.160.445
1pd9CO4Dihydrofolate reductase1.5.1.30.445
1t88CAMCamphor 5-monooxygenase1.14.15.10.445
1uzwCDHIsopenicillin N synthase1.21.3.10.445
1z1fSTLResveratrol synthase/0.445
2g1n1IGRenin3.4.23.150.445
2gstGPSGlutathione S-transferase Mu 12.5.1.180.445
2hizLIJBeta-secretase 13.4.23.460.445
2oapANPType II secretion system protein (GspE-2)/0.445
2rl1UD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.445
2rqfJH3Hemolymph juvenile hormone binding protein/0.445
2xtnGTPGTPase IMAP family member 2/0.445
3eksCY9Actin-5C/0.445
3i25MV7Beta-secretase 13.4.23.460.445
3kkzSAMUncharacterized protein/0.445
3rufNADUDP-N-acetylglucosamine 4-epimerase/0.445
3tr05GPGuanylate kinase/0.445
3v0p4GWHisto-blood group ABO system transferase/0.445
3w78CBDFMN-dependent NADH-azoreductase/0.445
4a84DXCMajor pollen allergen Bet v 1-A/0.445
4acxS8ZBeta-secretase 13.4.23.460.445
4djy0KRBeta-secretase 13.4.23.460.445
1cbfSAHCobalt-precorrin-4 C(11)-methyltransferase2.1.1.2710.444
1ep1FMNDihydroorotate dehydrogenase B (NAD(+)), catalytic subunit1.3.1.140.444
1nhpFADNADH peroxidase1.11.1.10.444
1rneC60Renin3.4.23.150.444
2ag5NAD3-hydroxybutyrate dehydrogenase type 2/0.444
2i7nACOPantothenate kinase 12.7.1.330.444
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.444
3ndcSAHPrecorrin-4 C(11)-methyltransferase2.1.1.1330.444
3qfaFADThioredoxin reductase 1, cytoplasmic1.8.1.90.444
3uzwNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.444
4bftZVTPantothenate kinase2.7.1.330.444
4bfuZVUPantothenate kinase2.7.1.330.444
4hp8NAP2-deoxy-D-gluconate 3-dehydrogenase/0.444
4ips1G4Mycocyclosin synthase1.14.21.90.444
4nd4NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.444
4uugPXGBranched-chain amino acid aminotransferase, putative/0.444
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.444
5c6cCMPcGMP-dependent protein kinase 22.7.11.120.444
5hwrCOAHydroxymethylglutaryl-CoA synthase/0.444
1bwlFMNNADPH dehydrogenase 11.6.99.10.443
1bxkNADdTDP-glucose 4,6-dehydratase 2/0.443
1hbvGANGag-Pol polyprotein/0.443
1kkq471Peroxisome proliferator-activated receptor alpha/0.443
1n2sNAIdTDP-4-dehydrorhamnose reductase1.1.1.1330.443
1vp6CMPCyclic nucleotide-gated potassium channel mll3241/0.443
1x1cSAHC-20 methyltransferase/0.443
3to6LYS_CMCHistone acetyltransferase ESA1/0.443
4a802ANMajor pollen allergen Bet v 1-A/0.443
4ambDUDPutative glycosyl transferase/0.443
4eagATP5'-AMP-activated protein kinase subunit gamma-1/0.443
4f5yC2EStimulator of interferon genes protein/0.443
4iae1DXAlr2278 protein/0.443
4kp71UQ1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic1.1.1.2670.443
4l0qNADAlcohol dehydrogenase class-3/0.443
1nqw5YL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.442
1nuuNADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.442
1p5rCOAFormyl-CoA:oxalate CoA-transferase/0.442
2fznFADBifunctional protein PutA1.5.5.20.442
2gz7D3FOrf1a polyprotein/0.442
2iko7IGRenin3.4.23.150.442
2wedPP6Penicillopepsin-13.4.23.200.442
2zbaZBATrichothecene 3-O-acetyltransferase/0.442
2ztsADPUncharacterized protein/0.442
2zvbSAHPrecorrin-3 C17-methyltransferase/0.442
3dys5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.442
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.442
3vswR31Renin3.4.23.150.442
4a312CBGlycylpeptide N-tetradecanoyltransferase/0.442
4dmmNAP3-oxoacyl-[acyl-carrier-protein] reductase/0.442
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.442
4gz612VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.442
4jnkNAIL-lactate dehydrogenase A chain1.1.1.270.442
4plpNADHomospermidine synthase2.5.1.440.442
1civNAPMalate dehydrogenase [NADP], chloroplastic1.1.1.820.441
1dr2TAPDihydrofolate reductase1.5.1.30.441
1egdFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.441
1f8wFADNADH peroxidase1.11.1.10.441
1nzdUPGDNA beta-glucosyltransferase/0.441
1rp0AHZThiamine thiazole synthase, chloroplastic/0.441
1yb5NAPQuinone oxidoreductase1.6.5.50.441
2ch6ADPN-acetyl-D-glucosamine kinase2.7.1.590.441
2ft9CHDFatty acid-binding protein 2, liver/0.441
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.441
2omeNADC-terminal-binding protein 2/0.441
2p4j23IBeta-secretase 13.4.23.460.441
2vcmM11Isopenicillin N synthase1.21.3.10.441
2y3rTIRTamL/0.441
3coy53HPantothenate synthetase6.3.2.10.441
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.441
3iqiASN_GLU_ASN_ILECysteine synthase2.5.1.470.441
3jv7NADSecondary alcohol dehydrogenase/0.441
3keuATPPyridoxal kinase2.7.1.350.441
3lb8FADPutidaredoxin reductase1.18.1.50.441
3mvqNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.441
3so9017Pol protein/0.441
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.441
4du82P0Mevalonate diphosphate decarboxylase/0.441
4ewo996Beta-secretase 13.4.23.460.441
4gkvNADAlcohol dehydrogenase, propanol-preferring1.1.1.10.441
4i0h1BLBeta-secretase 13.4.23.460.441
4wucANPDNA gyrase subunit B/0.441
5cmsAPRO-acetyl-ADP-ribose deacetylase/0.441
5eioNAP[LysW]-L-2-aminoadipate 6-phosphate reductase/0.441
1a4iNDPC-1-tetrahydrofolate synthase, cytoplasmic1.5.1.50.440
1bdlIM1Gag-Pol polyprotein3.4.23.160.440
1bxqPP8Penicillopepsin-13.4.23.200.440
1fxsNAPGDP-L-fucose synthase/0.440
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.440
1qbqHFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.440
1qbqHFPProtein farnesyltransferase subunit beta2.5.1.580.440
1qoqIGPTryptophan synthase alpha chain/0.440
1qr6NADNAD-dependent malic enzyme, mitochondrial1.1.1.380.440
1w4zNAPPutative ketoacyl reductase1.3.10.440
1xq6NAPUncharacterized protein At5g02240/0.440
2a5kAZPReplicase polyprotein 1ab3.4.220.440
2ddoATPPyridoxine/pyridoxal/pyridoxamine kinase/0.440
2dftADPShikimate kinase2.7.1.710.440
2iebZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
2nnlNAPDihydroflavonol 4-reductase1.1.1.2190.440
2p8uCOAHydroxymethylglutaryl-CoA synthase, cytoplasmic2.3.3.100.440
2uxpCLMHTH-type transcriptional regulator TtgR/0.440
2vbdV10Isopenicillin N synthase1.21.3.10.440
3hadNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.440
3ieuGDPGTPase Era/0.440
3jsiWTCHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.440
3q43D66M1 family aminopeptidase3.4.110.440
3qt62P0Mevalonate diphosphate decarboxylase/0.440
3wqmB29Diterpene synthase3.1.7.80.440
4fxy0W2Neurolysin, mitochondrial3.4.24.160.440
4iv6FDAIsovaleryl-CoA dehydrogenase/0.440
4px9ADPATP-dependent RNA helicase DDX3X3.6.4.130.440
4x7uZM3Mycinamicin III 3''-O-methyltransferase2.1.1.2370.440
4z64ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.440
4zjuNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.440