sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2pak | TYD | TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase | 5.3.2.3 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2pak | TYD | TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase | 5.3.2.3 | 1.000 | |
| 2pam | TYD | TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase | 5.3.2.3 | 0.769 | |
| 2pa7 | TYD | TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase | 5.3.2.3 | 0.579 | |
| 4mzu | TYD | WxcM-like protein | / | 0.510 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.480 | |
| 4h9t | HL4 | Phosphotriesterase | / | 0.471 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.467 | |
| 1s64 | 778 | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.461 | |
| 4zu4 | 4TG | WxcM-like protein | / | 0.458 | |
| 1zg3 | 2HI | Isoflavone 4'-O-methyltransferase | / | 0.454 | |
| 4xnw | 2ID | P2Y purinoceptor 1 | / | 0.450 | |
| 1kr2 | TAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.449 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.449 | |
| 3ete | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.449 | |
| 4fj2 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.446 | |
| 1ci0 | FMN | Pyridoxamine 5'-phosphate oxidase | 1.4.3.5 | 0.445 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.445 | |
| 1szf | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.444 | |
| 1bwf | ATF | Glycerol kinase | / | 0.443 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.443 | |
| 4en4 | ATP | Pyridoxal kinase | 2.7.1.35 | 0.441 | |
| 4o8a | FAD | Bifunctional protein PutA | 1.2.1.88 | 0.441 | |
| 1o01 | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.440 | |
| 2zsa | ADP | Pantothenate kinase | 2.7.1.33 | 0.440 |