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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2p5nNDPAldo-keto reductase family 1 member C211.1.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2p5nNDPAldo-keto reductase family 1 member C211.1.11.000
2hejNDPAldo-keto reductase family 1 member C211.1.10.599
1q5mNDPProstaglandin-E(2) 9-reductase1.1.1.1890.494
2fvlNAPAldo-keto reductase family 1 member C41.1.1.2250.486
4jtqNAPAldo-keto reductase family 1 member C2/0.473
1s1rNAPAldo-keto reductase family 1 member C3/0.458
2hdjNDPAldo-keto reductase family 1 member C2/0.452
4xo7NAPAldo-keto reductase family 1 member C2/0.447