Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2p35SAHTrans-aconitate 2-methyltransferase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2p35SAHTrans-aconitate 2-methyltransferase/1.000
1rneC60Renin3.4.23.150.484
4dh60KNBeta-secretase 13.4.23.460.484
5e8jSAHmRNA cap guanine-N7 methyltransferase2.1.1.560.463
4h3j10WBeta-secretase 13.4.23.460.459
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.455
4u8iFDAUDP-galactopyranose mutase/0.454
3em0CHDFatty acid-binding protein 6, ileal (gastrotropin)/0.452
1bil0IURenin3.4.23.150.451
1xe55FEPlasmepsin-23.4.23.390.450
2yltFADPhenylacetone monooxygenase1.14.13.920.450
2zjmF1MBeta-secretase 13.4.23.460.449
4b7754MBeta-secretase 13.4.23.460.449
3vsxR32Renin3.4.23.150.447
4djy0KRBeta-secretase 13.4.23.460.447
2v13C40Renin3.4.23.150.446
1w4xFADPhenylacetone monooxygenase1.14.13.920.445
4gdeFDAUDP-galactopyranose mutase/0.445
2f3eAXQBeta-secretase 13.4.23.460.442
2ylzFADPhenylacetone monooxygenase1.14.13.920.441
1me6IVSPlasmepsin-23.4.23.390.440
3d91REMRenin3.4.23.150.440