Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2p2i608Vascular endothelial growth factor receptor 22.7.10.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2p2i608Vascular endothelial growth factor receptor 22.7.10.11.000
2qu6857Vascular endothelial growth factor receptor 22.7.10.10.619
3efl706Vascular endothelial growth factor receptor 22.7.10.10.599
3hng8STVascular endothelial growth factor receptor 12.7.10.10.573
3b8q900Vascular endothelial growth factor receptor 22.7.10.10.567
3dtwA96Vascular endothelial growth factor receptor 22.7.10.10.564
4aseAV9Vascular endothelial growth factor receptor 22.7.10.10.555
3cp9C19Vascular endothelial growth factor receptor 22.7.10.10.550
4c8b0LIReceptor-interacting serine/threonine-protein kinase 22.7.11.10.544
3vnt0JAVascular endothelial growth factor receptor 22.7.10.10.542
2oiqSTIProto-oncogene tyrosine-protein kinase Src2.7.10.20.527
4agwNG7Proto-oncogene tyrosine-protein kinase Src2.7.10.20.524
4fc00T2Serine/threonine-protein kinase B-raf2.7.11.10.524
5hi2BAXSerine/threonine-protein kinase B-raf2.7.11.10.518
3vhkBPKVascular endothelial growth factor receptor 22.7.10.10.515
4ksp1SUSerine/threonine-protein kinase B-raf2.7.11.10.515
2hyySTITyrosine-protein kinase ABL12.7.10.20.512
4o2z046Mitogen-activated protein kinase/0.511
3hv5R24Mitogen-activated protein kinase 14/0.510
4qrc0LIFibroblast growth factor receptor 42.7.10.10.508
2xir00JVascular endothelial growth factor receptor 22.7.10.10.504
4aa0AA0Mitogen-activated protein kinase 14/0.496
1iepSTITyrosine-protein kinase ABL12.7.10.20.494
3kq7KQ7Mitogen-activated protein kinase 14/0.492
4eyjN61Mitogen-activated protein kinase 132.7.11.240.481
3ctj320Hepatocyte growth factor receptor2.7.10.10.467
2og81N8Tyrosine-protein kinase Lck2.7.10.20.450
3ksdNADGlyceraldehyde-3-phosphate dehydrogenase 1/0.450
3eta351Insulin receptor2.7.10.10.446
3if9FADGlycine oxidase1.4.3.190.442
3w2rW2REpidermal growth factor receptor2.7.10.10.441
2c0tL3GTyrosine-protein kinase HCK2.7.10.20.440
3iw8HIZMitogen-activated protein kinase 14/0.440