sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2p1v | 5TN | Retinoic acid receptor RXR-alpha |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2p1v | 5TN | Retinoic acid receptor RXR-alpha | / | 1.000 | |
| 2p1u | 4TN | Retinoic acid receptor RXR-alpha | / | 0.718 | |
| 1rdt | L79 | Retinoic acid receptor RXR-alpha | / | 0.585 | |
| 3fc6 | REA | Retinoic acid receptor RXR-alpha | / | 0.575 | |
| 1fm6 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.571 | |
| 1mzn | BM6 | Retinoic acid receptor RXR-alpha | / | 0.566 | |
| 2p1t | 3TN | Retinoic acid receptor RXR-alpha | / | 0.565 | |
| 1xiu | REA | Retinoic acid receptor RXR | / | 0.554 | |
| 1fby | REA | Retinoic acid receptor RXR-alpha | / | 0.553 | |
| 3uvv | REA | Retinoic acid receptor RXR-alpha | / | 0.549 | |
| 1fm9 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.547 | |
| 3fal | REA | Retinoic acid receptor RXR-alpha | / | 0.544 | |
| 2acl | REA | Retinoic acid receptor RXR-alpha | / | 0.539 | |
| 1uhl | MEI | Retinoic acid receptor RXR-beta | / | 0.536 | |
| 1mvc | BM6 | Retinoic acid receptor RXR-alpha | / | 0.535 | |
| 3h0a | 9RA | Retinoic acid receptor RXR-alpha | / | 0.526 | |
| 1k74 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.524 | |
| 3oap | REA | Retinoic acid receptor RXR-alpha | / | 0.520 | |
| 4k4j | 1O8 | Retinoic acid receptor RXR-alpha | / | 0.518 | |
| 4m8h | R4M | Retinoic acid receptor RXR-alpha | / | 0.515 | |
| 4m8e | 29V | Retinoic acid receptor RXR-alpha | / | 0.509 | |
| 4k6i | 9RA | Retinoic acid receptor RXR-alpha | / | 0.507 | |
| 1xls | REA | Retinoic acid receptor RXR-alpha | / | 0.497 | |
| 1q5d | EPB | Epothilone C/D epoxidase | 1.14 | 0.453 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.452 | |
| 4apu | A2K | Progesterone receptor | / | 0.451 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.449 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.447 | |
| 3t8x | T8X | T-cell surface glycoprotein CD1b | / | 0.446 | |
| 1osv | CHC | Bile acid receptor | / | 0.445 | |
| 3bxx | QUE | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.445 | |
| 1xds | DRA | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.442 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.442 | |
| 3uza | T4G | Adenosine receptor A2a | / | 0.441 | |
| 2xc3 | RT8 | Steroid C26-monooxygenase | 1.14.13.141 | 0.440 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 3p99 | LNP | Lanosterol 14-alpha-demethylase | / | 0.440 |