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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2p0aANPSynapsin-3

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2p0aANPSynapsin-3/1.000
1px2ATPSynapsin-1/0.540
4iwyADPRibosomal protein S6--L-glutamate ligase/0.466
2vbdV10Isopenicillin N synthase1.21.3.10.449
3rv3ADPBiotin carboxylase6.3.4.140.449
1qiqACCIsopenicillin N synthase1.21.3.10.448
2i8cADPD-alanine--D-alanine ligase/0.440
2iviACWIsopenicillin N synthase1.21.3.10.440
4iwxADPRibosomal protein S6--L-glutamate ligase/0.440